The Effects of the Oral Supplementation with a Natural Keratin Hydrolysate (Kera-Diet®) on Hair and Nails: Randomized, Placebo and Benchmark-Controlled Clinical Trial on Healthy Females.
Telogen effluvium and its acute form are two of the commonest occurrences in a
trichology clinic, with patients claiming excessive hair shedding. ATE can occur in people of any age and ethnicity and is considered to be a quite common condition in either sex even if women are more
likely to have a lowered quality of life and restricted social contacts as compared to men as a result of hair loss.
Brittle nail syndrome is a common condition affecting up to 20% of the population, especially women
over 50 years of age. Nails affected by BNS appear ragged, thin, and dull. The clinical features of BNS include horizontal splits within the nail plate and increased longitudinal ridging or splitting. In BNS oral supplementation, trace elements and amino acids have been reported to be useful to ameliorate the nail plate condition.
We hypothesized that a nutritional approach, with nutrients of which the composition is
close to the human keratin, could be effective to decrease hair loss during telogen effluvium and to improve
brittle nails condition. At this purpose, a clinical study was designed to investigate
the efficacy of a natural keratin hydrolysate obtained from a non-human
source on both aTE and BNS. Furthermore, it demonstrates the role of nutrients in both aTE and BNS.
Trichol Cosmetol Open J. 2021; 4(1): 7-16. doi: 10.17140/TCOJ-4-115
