The Effect of L-Carnitine, Green Tea Extract and Lotus Leaf Extract on the Body Fat Percentage in High Energy Diet-Induced Obese Rats.
Obesity is a global concern. According to the estimation of the World Obesity Federation, the global number of overweight or obese adults will increase from 2 billion in 2014 to 2.7 billion by 2025. Obesity control is a major challenge to global public health. Compared with healthy people, obese people are more likely to suffer from diabetes, metabolic syndrome, dyslipidemia, hypertension, cardiovascular disease, knee arthritis, etc.
Green tea contains lots of antioxidant substances, such as catechins and tannins. Green tea can suppress oxidation in a dose dependent manner, and its resistance to oxidation is six-fold than
that of black tea. Previous studies confirmed that green tea is rich in catechins, which can regulate blood lipids, promote metabolism and reduce weight. An adult who drinks green tea containing 583
mg of catechins every day can reduce BMI, body fat, waist circumference and hip circumference.
As there is higher oil and fat content in high energy diet, besides the increase in blood free fatty
acid and triglyceride concentrations, the concentrations of liver triglycerides and cholesterol in the rats also increased significantly
In addition, the part of nuciferine also has the effect of improving lipid metabolism and anti-oxidation. Studies have shown that in vitro experiments, using oleic acid to induce Hepa G2 cells for experiments, nuciferine can reduce triglyceride accumulation and effectively reduce fatty acid content. Previous study indicated that nuciferine can reduce the weight gain and fat accumulation of high fat diet-fed rats, affect the intestinal microbial composition, increase short-chain fatty acids. The anti-obesity effect may be related to the composition of the intestinal flora and the regulation of potential functions.