The Effect of Adenotonsillectomy on Mean Platelet Volume and Neutrophil-to-Lymphocyte Ratio.
To explore the effect of adenotonsillectomy on mean platelet volume levels and neutrophil to lymphocyte ratio values in children with obstructive sleep apnea syndrome.
In total, 127 children who underwent adenotonsillectomy with a diagnosis of OSAS were
included in the study.
Mean pre-operative MPV values were 8.12±1.28 femtoliters and mean post-operative MPV values were 7.96±1.01 fL, respectively. Post-operative MPV values were significantly lower than pre-operative measurements.
Mean pre-operative NLR levels were 1.46±0.82 and post-operative NLR values were 1.42±1.01, respectively. Post-operative NLR values were significantly lower than pre-operative NLR values.
We observed statistically significant lower MPV levels and NLR values after adenotonsillectomy in children with OSAS.
Future randomized studies should explore the relationship between the MPV levels, NLR values and parameters in polysomnography in larger numbers of patients with OSAS.
Obstructive sleep apnea caused by repetitive upper airway obstruction, is a syndrome
characterized by recurrent episodes of sleep apnea and hypopnea. The incidence of OSA in
children is reported lower than adult.
Obstructive sleep apnea syndrome may inspire
poor concentration, excessive daytime somnolence, morning headaches, metabolic, cardiopulmonary and cardiovascular diseases, and a lower quality of life.
utilized to diagnose and evaluate the severity of OSAS, and it is accepted as the gold standard
diagnostic method for OSAS. The most common cause of OSAS in children is adenotonsillar
Mean platelet volume is used as a parameter of platelet functions. Larger
platelets are more reactive than platelets of normal platelets.
In conclusion, we observed statistically significant lower MPV
levels and NLR values after adenotonsillectomy in children with
Otolaryngol Open J. 2016; 2(4): 101-104. doi: 10.17140/OTLOJ-2-122