Relationship Between Serum Vitamin D Levels and Childhood Recurrent Tonsillitis.
Many factors are associated with the development of recurrent tonsillitis. These include patient incompliance, premature cessation of antibiotherapy, inadequate antibiotic absorbance, bacterial tolerance, bacterial load, bacterial biofilms, and immune system deficiencies.
To compare between recurrent tonsillitis patients undergoing three to seven tonsillitis episodes per year within less than two years with controls having less than three tonsillitis episodes per year on the basis of vitamin D levels.
A total of 426 patients were enrolled in this study. The patients were divided into two
groups according to the number of acute tonsillitis episodes: Those who had less than three
episodes per year (Group A) and those with three to seven episodes per year (Group B).
The total number of episodes of acute tonsillitis
within one year, demographic characteristics of the patients and the mean serum 25-hydroxyvitamin D levels of both groups were compared.
This is the first study investigating vitamin D levels among patients for the diagnosis of recurrent tonsillitis during the follow-up. However, further prospective randomized controlled studies are conducted to gain a better understanding as to whether vitamin D supplementation would reduce the tonsillectomy rates in the diagnosis of recurrent tonsillitis.
Acute tonsillopharyngitis is a clinical presentation which is usually characterized by clinical
acute inflammatory manifestations such as hyperemic tonsils and pharynx, exudation, and ulceration.
As previously described by Paradise et al, recurrent tonsillitis is defined as seven episodes of the condition within one year or five episodes in the preceding two years and more or three episodes in the preceding three years and more.
Otolaryngol Open J. 2017; 3(1): 16-21. doi: 10.17140/OTLOJ-3-135