Rapid Diagnosis of Hemosiderin-Laden Macrophages With Diff-Quick Stain.
A 77-year-old healthy woman was referred to our hospital with sudden
hemoptysis.
Chest X-ray showed moderate consolidation in the right upper
lung fields.
On hospital day urgent bronchoscopy was performed and sequential
Bronchoalveolar lavage fluid obtained from segment 2 of
the right lung was progressively more hemorrhagic.
Of note, cytological evaluation with rapid Diff-quick stain
demonstrated the presence of numerous large Alveolar
Macrophages engulfing yellow-colored material, so-called
Hemosiderin-laden macrophages together with abundant red blood cells
in the background.
On Papanicolaou staining, intracytoplasmic hemosiderin
accumulation in the AMs was seen as faint, brown-colored,
dense deposits. She was thus tentatively
diagnosed with idiopathic alveolar hemorrhage.
Chest X-ray showed moderate
consolidation in the right upper lung fields.
Of note, cytological evaluation with rapid Diff-quick stain demonstrated
the presence of numerous large Alveolar Macrophages engulfing
yellow-colored material, so-called Hemosiderin-laden macrophages
together with abundant red blood cells in the background.
A and B. Cytological evaluation with rapid Diff-quick stain
demonstrated
the presence of numerous large Alveolar Macrophages
engulfing yellow-colored material.
On hospital day urgent bronchoscopy was performed and sequential
Bronchoalveolar lavage fluid obtained from segment 2 of
the right lung was progressively more hemorrhagic.
Of note, cytological evaluation with rapid Diff-quick stain
demonstrated the presence of numerous large Alveolar.
Macrophages engulfing yellow-colored material,
so-called Hemosiderin-laden macrophages together with abundant red blood cells
in the background.
Pulm Res Respir Med Open J. 2016; 2(4): 128. doi: 10.17140/PRRMOJ-2-122
