Papillary Microcarcinoma of Thyroid in Resected Benign Multinodular Goiters Shows Correlation with Weight of the Specimen.
Practically, every old simple goiter changes into multi-nodular goiter. Extreme thyroid enlargement is mainly produced by multi-nodular goiter and is more commonly mistaken for tumor
than any other variety of thyroids illness.
Neoplastic alteration may occur in these hyperplastic places which are very tiny and can be
missed by pathologists in slides stained with routine methods.
The incidence of thyroid carcinoma has increased in recent years due to improvement in diagnostic techniques, e.g. an increase in fine needle aspiration cytology and radiology procedures like ultrasound, computed tomography-scan and magnetic resonance imaging.
The thyroid cancer in Pakistan is accountable for 1.2% cases of all cancers. Earlier information from Pakistan showed PTC to comprise 57-89% of all thyroid malignancies.
Unfortunately, recent data for thyroid malignancies papillary microcarcinoma of thyroid in Pakistan is not available, but most probably the small tumors might have been picked up incidentally in employment health screening or using imaging studies for other medical conditions.
Unlike western world the healthcare system in Pakistan does not have a proper thyroid
screening program. PMCT is considered to be the most common type of papillary carcinoma in the USA.
The PMCT is defined as a tumor one cm or less, that is generally found incidentally on histopathologic examination after thyroidectomy. It is basically discovered by vigilant assessment of removed thyroid specimens.
The identification of PMCT in thyroid surgical pathology specimens ranges from 1-24% in one series and in 6-36% of autopsy specimens in another study. PMCT is increasing in all age groups and in the United States it is more common after 45-years. This change linking age and frequency have vital prognostic and management options.
Pathol Lab Med Open J. 2021; 1(1): 63-69. doi: 10.17140/PLMOJ-1-110