Medicinal Value of Croton macrostachyus and Solanum incanum against Causative Agent of Foodborne Diseases

*Corresponding author: Tagesu Abdisa*


Foodborne diseases are a public health threat which causes a large economic impact across the worldwide. Escherichia coli (E. coli), Listeria monocytogenes (L. monocytogenes), Salmonella species (S. species), Staphylococcus aureus (S. aureus) and many more other organisms are the leading causes of foodborne illness and death in the world. Increment of antibiotic resistance exhibited by the actions of microbial infectious agents has led to screening of several medicinal plants for their potential antimicrobial activity. Therefore, the aim of this paper is to review on the medicinal value of Croton macrostachyus (C. macrostachyus) and Solanum incanum (S.incanum) against causative agents of foodborne disease. Antimicrobial compounds of medicinal plants differ from antibiotics as they have fewer side effects, better patient tolerance, relatively less expensive, acceptance due to a long history of use and being renewable in nature. There are so many medicinal plants used to treat foodborne diseases which associated with gastroenteritis in humans and animals, among plants S. incanum and C. macrostachyus are the common for treatment of foodborne diseases associated with diarrhea. S. incanum has different bioactive substances which have medicinal importance against skin diseases, abdominal pains, fever, stomachaches and indigestion, treatment of dandruff, wounds, sore throat, angina, ear inflammation, liver disorders, wart and ringworm and treatment of cow driosis, dermatophilosis, foot rot, pasteurellosis, black leg, fasciolosis and snake bite. Bioactive compounds which present in S. incanum are including alkaloids, steroids, saponins, tannins, glycosides, flavonoid and terpenoids. C. macrostachyus is medicinal plant which have bioactive compounds including terpenoids, alkaloids, flavonoids, lignoids, proanthcyanidins, sesquiterpenoids and lupeol, saponnins, resins, crotepeoxide. C. macrostachyus have medicinal value in treatment of malaria, rabies, gonorrhea, wound, diarrhea, hepatitis, jaundice, abdominal pain, cancer, toothache, pneumonia, typhoidand gastrointestinal disorder. Which is also used as abortifacient and uterotonic to expel retained placenta. Therefore, S. incanum and C. Macrostachyus have different medicinal value against foodborne disease and drug-resistance infectious agents. However, an advanced study have not been conducted on the extract of pure bioactive compounds and toxicity analysis. Therefore, further studies should have to be conducted to extract pure compounds from these medicinal plants for pharmaceutics industry.


Bioactive substance; Drug resistance; Food borne disease; Infectious agent; Medicinal plants.