Innovation of Wound and Burn Care Dressings from Traditional to Nonwoven Polymeric Scaffolds.
Health care professionals often come across patients inflicted with exuding wounds
and burn injuries which get infected with broad range of micro-organisms because wounds often provide a favourable environment for the colonization of microbes.
Staphylococcus aureus and Trichophyton rubrum are the most common pathogens which are responsible for skin and nail infection. Some deep wounds and burns damage the underlying structures like muscle, tendon, blood vessels, nerves, and bone which need persistent medical care to prevent systemic infection and loss of organ function.
Sometimes, aggressive wound infection can cause septicemia and death. The remit of this editorial is to highlight the innovation of biocompatible nanofiber dressings for the
localized delivery of antiseptics, antibiotics and growth factors which promote wound and burn healing.
Currently, the development of a variety of biocompatible dressings are the focus of attention of biomedical researchers.
These dressings serve as vehicle for the promising delivery of wound or burn care ingredients or even allogenic cells which may provide a specific wound healing benefit. Further, the dressing acts to maintain a locally moist environment needed for wound healing.
Several studies and experimental evidence suggest that nanofibers with diameter range of 50-100 nm have a great potential for making nanofiber dressings for wound care due to their large surface area, high porosity, and small pore size.
Nonwoven nanofibrous scaffolds or patches for wound care have shown to produce skin substitutes with optimal cellular organization, proliferation
and to reduce wound contraction.
Pathol Lab Med Open J. 2016; 1(1): e4-e7. doi: 10.17140/PLMOJ-1-e002