Hazard Assessments of Cattle Fascioliasis With Special Reference to Hemato-Biochemical Biomarkers.
Fascioliasis is a well known veterinary trouble in cattle and is to date an important human being disease. The aim of this study was to evaluate the functional capacity of the liver based on the activity of specific enzymes, proteins and glucose in serum and also to investigate the influence of mechanical and toxic effects of fascioliasis on blood picture and biliary tract of cattles.
Fasciolosis is a systemic parasitic disease of cattle caused by the liver flukes, Fasciola gigantica
and Fasciola hepatica (trematodes of the genus Fasciola). Fascioliasis merits particular consideration due to its global distribution in livestock and the estimation of up to 17 million
people infected worldwide. It is an important hepatic disease causing great enormous economic
losses in ruminants and in livestock industries through animal mortality, growth retardation,
sterility, condemnation of affected livers and expense due to control measures.
Apart from its high veterinary importance, fasciolosis is a secondary zoonotic infection of a good number of human populations in every continent of the world. The increasing importance of human fascioliasis is also related to its pathogenicity and immunity. This disease is pronouncedly complicated, including difficulties in diagnosis, its great morbidity and immunological impact on children in long-term infection particularly in human fascioliasis endemic areas.
This produces cholangitis, biliary obstruction, destruction and fibrosis of hepatic tissue and anaemia.28 The detected hyperglobulinaemia could be as a result of immune response to infection10 and due to the increase in α and β globulin production.
Vet Med Open J. 2017; 2(1): 12-18. doi: 10.17140/VMOJ-2-111
