Effects of Garcinia Cambogia Compounded Supplements on the Formation of Body Fat Induced by a High Energy Diet in Obese Rats.
According to a World Health Organization (WHO) survey, the number of obese people in the world has tripled since 1975. In 2016, over 1.9 billion adults aged 18-years or older were overweight; 650 million of those overweight people were obese. In countries with the largest part of the world’s population, more people die from being overweight or obese than from being underweight.
Among overweight or obese men and women, the prevalence of hypertension, type II diabetes, gallbladder disease, and osteoarthritis all rise sharply with increased weight. Many obese people seek surgery or drug treatments, but gastric bypass surgery may lead to long-term vitamin and mineral deficiencies, post-operative complications, or even premature death.
Weight-loss drugs have also been reported to lead to uncomfortable side effects in the human body: for instance, Qsymia® is a combination of phentermine and topiramate, the adverse effects of the two medications individually including headache, insomnia, depression, concentration; the side effects of taking orlistat include oily stools, diarrhea, stomach aches, and adverse reactions in the liver; and Contrave® is a combination of bupropion and naltrexone, which may cause headache, vomiting, constipation, insomnia. To prevent obesity and ensure the dietary safety of obese people, the development of natural and safe weight-loss supplements with no side effects merits further study, in the hopes that natural ingredients can help improve fat metabolism, control body weight, and reduce fat accumulation in obese people.
Obes Res Open J. 2021; 8(1): 18-25. doi: 10.17140/OROJ-8-147