Cutaneous Polyarteritis Nodosa in Adult Patient

Cristiana S. Santos*, Samuel S. Álvarez and González Moran

Cutaneous Polyarteritis Nodosa in Adult Patient

Polyarteritis nodosa is a systemic vasculitis that involves small
and medium-sized arteries. Cutaneous polyarteritis nodosa
(PNC) is a rarer variant of classic polyarteritis nodosa that presents
with tender subcutaneous nodules, articular involvement, myalgia
and peripheric neurological involvement.

Polyarteritis nodosa is a systemic vasculitis that involves small
and medium-sized arteries. Cutaneous polyarteritis nodosa
(PNC) is a rarer variant of classic polyarteritis nodosa that presents
with tender subcutaneous nodules, articular involvement, myalgia
and peripheric neurological involvement.

A 41-year-old male patient presented with fever and history of
myalgia of the scapular and pelvic girdle, purple reticulated net-like
lesions in the upper and lower region, torso and hands compatible
with livedo reticularis, major weight bearing joints arthritis (right
knee, left shoulder and proximal interphalangeal joints) and paranesthesia.

The patient had no significant past medical history, no
medication, alcohol or tobacco consumption, no history of highrisk sexual
behaviors and no common contact with animals.

Laboratory workup, complete blood count, liver and kidney function
tests and urinalysis, were within normal ranges, except for
elevated acute phase reactants, erythrocyte sedimentation rate
(ESR) and C-reactive protein (CRP). Comprehensive infectious
work-up was negative.

Autoantibodies, including anti-nuclear antibodies (ANA),
anti-double-stranded deoxyribonucleic acid (DNA)
antibodies (anti-DNAds), and rheumatoid factor, were negative.

Complement factors, creatine kinase (CK) and aldolase were normal.
Anti-neutrophil cytoplasmic (pANCA and c-ANCA), antimyelperoxidase
(anti-MPO) and anti-proteinase antibodies (antiPR3), anti-Saccharomyces
cerevisiae antibodies and antiphospholipid
antibodies were all negative.

Immunoglobulin profile was normal.
Hepatitis virus, human immunodeficiency virus (HIV), syphilis,
cytomegalovirus (CMV), Borrelia burgdorferi, rickettsia coronii,
echovirus, A19 and B coxsackie and B19 parvovirus antibodies
were negative.

Osteol Rheumatol Open J. 2020; 1(1): 61-63. doi: 10.17140/ORHOJ-1-115