Comparison of Hispanics to Caucasians in Metabolic Evaluation of Nephrolithiasis
The Hispanic population is the largest minority group in the
United States and constitutes 17% of the population.
Projections show that by 2060, Hispanics will make up 31% of the US population.
Little is known regarding Hispanic-Americans in regards to the metabolic
risk of stones and how this compares to the Caucasian-American population,
which is traditionally the largest group of stone formers.
Our Institution is located within a state where Hispanics
are the majority and that has the highest percentage of Hispanics
in the country at 47.3%. This allows for a unique comparison of
Hispanics to Caucasians within one geographic region.
After institutional IRB approval, a retrospective review was
performed at our single tertiary care center.
All patients diagnosed with kidney stones who underwent
a 24 hour urine stone risk analysis at our institution from 2008-2013 were evaluated.
This left 208 patients with 349 urine studies including 122 Caucasians
and 87 Hispanics with 206 and 143 urine studies, respectively.
Table 2 shows the urinary parameter measurements for each group.
Group A had a higher mean urine volume of 2.24 liters compared
to 2.21 liters in Group B (p=0.006).
When comparing the two groups for all tests completed, several 24 hour urine
parameters were significantly different. Table 2 shows the urinary parameter
measurements for each group.
Group A had a higher mean urine volume of 2.24 liters compared
to 2.21 liters in Group B (p=0.006). Group A had significantly
higher urinary oxalate, potassium, phosphorus, sulfate, urine urea
nitrogen and 24 hour creatinine compared to Group B.
Group A had lower urinary citrate, supersaturation of calcium phosphate
and magnesium levels. Remaining urinary parameters were not
significantly different.
Urol Androl Open J. 2018; 3(1): 1-5. doi: 10.17140/UAOJ-3-116