1. Young AJ, Johnson S, Steffens DC, Doraiswamy PM. Coenzyme Q10: a review of its promise as a neuroprotectant. CNS Spectr. 2007; 12(1): 62-68. doi: 10.1017/S1092852900020538
2. Crane FL. Biochemical functions of coenzyme Q10. J Am Coll Nutr. 2001; 20(6): 591-598. doi: 10.1080/07315724.2001.10719063
3. Dhanasekaran M, Ren J. The emerging role of coenzyme Q-10 in aging, neurodegeneration, cardiovascular disease, cancer and diabetes mellitus. Curr Neurovasc Res. 2005; 2(5): 447-459. doi: 10.2174/156720205774962656
4. Khatta M, Alexander BS, Krichten CM, et al. The effect of coenzyme Q10 in patients with congestive heart failure. Ann Intern Med. 2000; 132(8): 636-640. doi: 10.7326/0003-4819-132-8-200004180-00006
5. Beal MF. Therapeutic effects of coenzyme Q 10 in neurodegenerative diseases. Methods Enzymol. 2004; 382: 473-487. doi: 10.1016/S0076-6879(04)82026-3
6. Kolahdouz MR, Hosseinzadeh-Attar M, Eshraghian M, Nakhjavani M, Khorami E, Esteghamati A. The effect of coenzyme Q10 supplementation on metabolic status of type 2 diabetic patients. Minerva Gastroenterol Dietol. 2013; 59(2): 231-236. Web site. http://europepmc.org/abstract/med/23831913. Accessed April 19, 2016
7. Hodgson J, Watts G, Playford D, Burke V, Croft K. Original communication-coenzyme Q10 improves blood pressure and glycaemic control: a controlled trial in subjects with type 2 diabetes. Eur J Clin Nutr. 2002; 56(11): 1137-1142. doi: 10.1038/sj.ejcn.1601464
8. Singh R, Niaz M, Rastogi S, Shukla P, Thakur A. Effect of hydrosoluble coenzyme Q10 on blood pressures and insulin resistance in hypertensive patients with coronary artery. J Hum Hypertens. 1999; 13(3): 203-208. doi: 10.1038/sj.jhh.1000778
9. Semple RK. EJE PRIZE 2015: How does insulin resistance arise, and how does it cause disease? Human genetic lessons. Eur J Endocrinol. 2016; 174(5): R209-R223. doi: 10.1530/EJE-15-1131
10. Whiteman EL, Cho H, Birnbaum MJ. Role of Akt/protein kinase B in metabolism. Trends Endocrinol Metab. 2002; 13(10): 444- 451. doi: 10.1016/S1043-2760(02)00662-8
11. Amin MM, Asaad GF, Salam RMA, El-Abhar HS, Arbid MS. Novel CoQ10 antidiabetic mechanisms underlie its positive effect: modulation of insulin and adiponectine receptors, tyrosine kinase, PI3K, glucose transporters, sRAGE and visfatin in insulin resistant/diabetic rats. PloS one. 2014; 9(2): e89169. doi: 10.1371/journal.pone.0089169
12. Zahedi H, Eghtesadi S, Seifirad S, et al. Effects of CoQ10 supplementation on lipid profiles and glycemic control in patients with type 2 diabetes: a randomized, double blind, placebo-controlled trial. J Diabetes Metab Disord. 2014; 13(1): 1-8. doi: 10.1186/s40200-014-0081-6
13. Sena CM, Nunes E, Gomes A, et al. Supplementation of coenzyme Q 10 and α-tocopherol lowers glycated hemoglobin level and lipid peroxidation in pancreas of diabetic rats. Nutr Res. 2008; 28(2): 113-121. doi: 10.1016/j.nutres.2007.12.005
14. Mezawa M, Takemoto M, Onishi S, et al. The reduced form of coenzyme Q10 improves glycemic control in patients with type 2 diabetes: an open label pilot study. Biofactors. 2012; 38(6): 416-421. doi: 10.1002/biof.1038
15. Amin MM, Asaad GF, Abdel Salam RM, El-Abhar HS, Arbid MS. Novel CoQ10 antidiabetic mechanisms underlie its positive effect: modulation of insulin and adiponectine receptors, Tyrosine kinase, PI3K, glucose transporters, sRAGE and visfatin in insulin resistant/diabetic rats. PLoS One. 2014; 9(2): e89169. doi: 10.1371/journal.pone.0089169
16. Kahn SE, Hull RL, Utzschneider KM. Mechanisms linking obesity to insulin resistance and type 2 diabetes. Nature. 2006; 444(7121): 840-846. doi: 10.1038/nature05482
17. Qatanani M, Lazar MA. Mechanisms of obesity-associated insulin resistance: many choices on the menu. Genes Dev. 2007; 21(12): 1443-1455. doi: 10.1101/gad.1550907
18. Yadav A, Kataria MA, Saini V, Yadav A. Role of leptin and adiponectin in insulin resistance. Clin Chim Acta. 2013; 417: 80-84. doi: 10.1016/j.cca.2012.12.007
19. Stofkova A. Resistin and visfatin: regulators of insulin sensitivity, inflammation and immunity. Endocr Regul. 2010; 44(1): 25- 36. Web site. http://europepmc.org/abstract/med/20151765. Accessed April 19, 2016
20. Denroche HC, Huynh FK, Kieffer TJ. The role of leptin in glucose homeostasis. J Diabetes Investig. 2012; 3(2): 115-129. doi: 10.1111/j.2040-1124.2012.00203.x
21. Stumvoll M, Goldstein BJ, van Haeften TW. Type 2 diabetes: principles of pathogenesis and therapy. Lancet. 2005; 365(9467): 1333-1346. doi: 10.1016/S0140-6736(05)61032-X
22. Nedvidkova J, Smitka K, Kopsky V, Hainer V. Adiponectin, an adipocyte-derived protein. Physiol Res. 2005; 54(2): 133-140. Web site. http://search.proquest.com/openview/2443a3956e202092b6c8241770459c20/1?pq-origsite=gscholar. Accessed April 19, 2016
23. Wei Z, Peterson JM, Lei X, et al. C1q/TNF-related protein-12 (CTRP12), a novel adipokine that improves insulin sensitivity and glycemic control in mouse models of obesity and diabetes. J Biol Chem. 2012; 287(13): 10301-10315. doi: 10.1074/jbc.M111.303651
24. Enomoto T, Ohashi K, Shibata R, et al. Adipolin/C1qdc2/CTRP12 protein functions as an adipokine that improves glucose metabolism. J Biol Chem. 2011; 286(40): 34552-34558. doi: 10.1074/jbc.M111.277319