Clear Cell Myoepithelioma: A Rare Presentation in Nasal Cavity.
Myoepitheliomas are predominantly tumors of salivary glands constituting less than 1% of
all salivary gland tumors. A 65 year old women presented with bleeding unilateral mass for 03 months.
Contrast Enhanced Computed Tomography revealed a heterogeneously
enhancing mass lesion arising from right anterior
ethmoid air cells and filling the right nasal
cavity entirely. Endoscope guided endoscopic biopsy was performed.
Histopathological examination showed a well circumscribed tumour
arranged in small glands and sheets. Tumor cell
were immunopositive for S100, Cytokeratin and
Vimetin while negative for
chromogranin, synaptophysin, CD 10 and Smooth Muscle Actin.
Nasal myoepitheliomas are composed
of myoepithelial cells with solid, myxoid or reticular patterns
of growth. The cells themselves
may be clear-cell type, spindle-shaped, plasmacytoid and epithelioid.
In all reported cases of myoepithelioma, surgery was the mainstay treatment. Partial maxillectomy via a lateral rhinotomy approach, Caldwell-Luc procedure has been recommended for patients who were suspected to have a low-grade sarcomatous neoplasm.
Myoepitheliomas are predominantly tumors of salivary glands constituting less than 1% of all salivary gland tumors. A 65 years old lady presented with complains of intermittent bleeding for 3 months and nasal obstruction on the right side for 2 months.
There were no known comorbidities. On examination patient had a bulge over right lateral wall of nose seen externally. Anterior rhinoscopy revealed a fleshy smooth mass filling right nasal cavity.
Otolaryngol Open J. 2016; 2(3): 77-79. doi: 10.17140/OTLOJ-2-117