Association of Pseudo-Meigs’ Syndrome with Struma Ovarii and High CA125 Mimicking Ovarian Malignancy
Struma ovarii is a rare ovarian neoplasm composed predominantly of normal thyroid
tissue and categorized as a variety of mature teratomas, representing only 2.7% of germ cell
ovarian tumors.
It is generally benign, although it can present malignant transformation in
5-7% of cases, and is even more unusual as a metastatic disease.
The majority of cases are asymptomatic, but can be associated with a certain amount of ascitic fluid in up to 15-20% of the former, with reports of association with the hydrothorax, and development of the clinical
features currently recognized as pseudo-Meigs’syndrome (PMS).
Among 20 cases reported as pseudo-Meigs’syndrome in a review of the literature from 1994-2014, only eight were related with struma ovarii (Table 1). The importance of this syndrome in benign pathology renders its
recognition difficult.
Here, we present the case of a patient with struma ovarii associated with ascites, pleural effusion, and elevated CA125, simulating a malignant neoplasm of the ovary.
Clinical history of importance, with complaint of abdominal distension. The patient reported her illness as having initiated 4 months previously, with an increase in abdominal perimeter, not painful, in addition to precordial.
Gynecol Obstet Res Open J. 2015; 2(2): 57-61. doi: 10.17140/GOROJ-2-113
