Wen-Hai Chou*, Guona Wang, Varun Kumar and Yi-Chinn Weng

Abstract

Stroke is a leading cause of adult disability in the United States. However, limited
number of molecularly targeted therapy exists for stroke. Recent studies have shown that Lipocalin-
2 (LCN2) is an acute phase protein mediating neuroinflammation after ischemic and
hemorrhagic strokes. This review is an attempt to summarize some LCN2-related research findings
and discuss its role in stroke.