Xu Zeng, MD, PhD


Associate Professor
Department of Pathology and Laboratory Medicine
Temple University Hospital
3401 North Broad Street-Room A2-F326 2PAP
Philadelphia, Pennsylvania 19140, USA

Biography

EDUCATION AND TRAINING

• (09/1980-08/1985) BA, Medicine Guangzhou Medical College Guangzhou, P.R. China
• (09/1991-06/1996) PhD, Pharmacology Medical College of Ohio Toledo, Ohio, USA
• (09/1985-08/1991) Residency, Surgery The Second Guangzhou Medical College Hospital Guangzhou, P.R. China
• (07/2000-06/2004) Residency, Pathology North Shore Uni-Long Island Jewish Medical Ctr New Hyde Park, New York
• (07/2004-08/2005) Fellowship Renal Pathology Johns Hopkins Medical Institute Baltimore, Maryland

Research Interest

His Research interest includes: Pathology.

Scientific Activities

MEMBERSHIP

• (2005-2012) Member of Detroit Medical Center, Nephrology, Multidisciplinary Team
• (2009-2012) Member of the Tissue Procurement Program, Nephrology, Wayne State University
• (2005-2012) Member, Clinical Faculty Research Working Group, Wayne State University
• (2005-2012) Director of Pathology Education, Nephrology, Wayne State University
• (2005-2012) Anatomic Pathology Consult Committee Member, Harper University Hospital, Detroit Medical Center

HONORS AND AWARDS

• (1996) Graduate Deans Award, PhD in Medical Science. Medical College of Ohio
• (1996) People Choice Award Favorite Poster/Presentation, Research Forum. Medical College of Ohio
• (2009) Recognition Award for significant contribution to the Nephrology Fellows teaching. Wayne state University School of Medicine, Nephrology

Publications

PEER-REVIEWED ARTICALS

1. Zeng X, Xie XH, Tietz EI. Impairment of feed forward inhibition in CA 1 region of hippocampus after chronic benzodiazepine treatment. Neurosci lett. 1994; 173: 40-44. doi: 10.1016/0304-3940(94)90145-7
2. Zeng X, Xie XH, Tietz EI. Reduction of GABA-medicated inhibitory postsynaptic potentials in hippocampus CA1 pyramidal cells following oral flurazepam administration. Neuroscience. 1995; 66: 87-89.
3. Zeng X, Tietz EI. Depression of both early and late monosynaptic inhibitory postsynaptic potentials in hippocampus CA1 neurons following chronic benzodiazepine treatment. Synapse. 1996; 25: 125-136. doi: 10.1002/(SICI)1098-2396(199702)25:2<125::AID-SYN3>3.0.CO;2-E
4. Zeng X, Tietz EI. Benzodiazepine tolerance at GABAergic synapses on hippocampal CA1 pyramidal cells. Synapse. 1999; 31: 263-277.
5. 5. Chen S, Huang X, Zeng X, Sieghart W, Tietz, EI. Benzodiazepine-mediated regulation of alpha1-2, ß1-3 and alpha2 GABAA subunit proteins in the rat brain hippocampus and cortex. Neuroscience. 1999; 93: 33-44
6. Zeng X, Tietz EI. Role of bicarbonate in mediating conductance in benzodiazepine tolerant hippocampal CA1 pyramidal cells. Brain Research. 2000; 868: 202-241.
7. Tietz EI, Zeng X, Chen S, et al. Antagonist-induced reversal of functional and structural measures of hippocampal BZ tolerance. J Phamacol ExpTher. 1999; 291: 932-935.
8. Tietz EI, Shanyi C, Zeng X, Sieghart W. Role of protein kinase A in GABAA receptor dysfunction in CA1 pyramidal cells following chronic benzodiazepine treatment. J Neurochem. 2003; 85(4): 988-998.
9. Zeng X, El-Amm, J.M, et al. Intermediate-term outcomes with early steroid withdrawal in African-American renal transplant recipients undergoing surveillance biopsy. Surgery. 2007; 142(4): 538-545. doi: 10.1016/j.surg.2007.07.006
10. Franco C, Yoo W, Zeng X. Lupus nephritis in an African American Population. The International Journal of Medicine. 2009.
11. Franco C, Yoo W, Franco D, Zeng X. Predictors of end stage renal disease in African American with lupus nephritis. Bulletin of the NYU Hospital for Joint disease. 2010; 68 (4): 251-256.
12. Liu X, Zhan H, Xu Z, Zhang C, Chen D. Dexmedetomidine reduced cytokines release in postpartum bleeding-induced multiple organs dysfunction syndrome rat. Submitted to Journal of Anesthesiology. 2013.
13. Bhat ZY, Bostwick DG, Hossain D, Zeng X. Participation of functionally active plasma cells in acute rejection and response to therapy in renal allografts. DNA and Cell Biology . 2014; 33(7): 1-7.
14. Gonzalez-Suarez M1, Waheed A, Andrews D, Ascherman D, Zeng X, Nayer A. Lupus vasculopathy. Diagnostic, pathogenetic and therapeutic considerations. Lupus. 2014; 23(4): 421-427. doi: 10.1089/dna.2014.2371
15. Zeng X, Adabala M, Bostwick DG, Hossain D, Mattoo T. Henoch-Scholein purpura nephritis in Children:. A severe IgA nephropathy. Scholarena Case report. 2014; 1(2): 201-208.
16. Zeng X, Hossain D, Bostwick D, Herrera G, Ballester B, Zhang PL. Urinary β2-microglobulin is a sensitive indicator for renal tubular injury. Scholarena Case report. 2014; 1(1): 103-108.
17. Ojemakinde K, Turbat-Herrera EA, Zeng X, Gu X, Herrera GA. The many faces of cryoglobulinemic nephropathy. A clinic-plthologic study of 43 cases with emphasis on the value of electron microscopy. Ultrastructural Pathology. 2014; 38(6): 367-376. doi: 10.3109/01913123.2014.952803
18. Herrera GA, Ojemakinde K, Turbat-Herrera EA, Gu X, Zeng X, Iskandar SS. Immunotactoid glomeruopathy and cryoglobulinemic nephropathy. Two entities with many similarities. A unified conceptual. Ultrastructural Pathology.
19. Zeng X, Hossain D, Bostwick D, Turbat-Herrera EA, Zhang PL. Urinary β2-microglobulin is a good indicator for renal proximal tubular injury: a correlative study with renal biopsies. J biomarkers. 2014; 1-7. doi: 10.1155/2014/492838
20. Cosner D, Zeng X, Zhang PL. Proximal tubular injury in medullary rays is a the first sign of acute tacrolimus nephrotoxicity.
21. Eskandari M, Zeng X, Zhang PL. Kidney injury molecule-1 is a sensitive and specific marker of acute tubular injury in pediatric renal biopsy. Journal of Transplantation. doi: 10.1053/j.ajkd.2008.01.020
22. Rao S, Ghanta M, Lee IJ, et al. Impact of HLA antibody monitoring and Kidney Transplantation. Clinical Transplant. 2003.