Shigaku Ikeda, MD, PhD

Professor and Chair
Department of Dermatology and Allergology
Faculty of Medicine
Graduate School of Medicine
Juntendo University, Tokyo, Japan



• (1982) MD, Juntendo University, School of Medicine, Tokyo
• (1986) Board Certified Dermatologist, Japanese Dermatological Association
• (1987) PhD, Juntendo University, Graduate School of Medicine, Tokyo
• (1993-1995) Postdoctoral fellow, Department of Dermatology, UCSF, San Francisco, CA, USA
• (1995-1996) Research Associate Professor, ibid


• (1987-1993) Lecturer, Department of Dermatology, Juntendo University, School of Medicine, Tokyo
• (1995-2002) Assistant Professor, Department of Dermatology, UCSF, San Francisco, CA, USA
• (2002-2004) Associate Professor, Department of Dermatology, UCSF, San Francisco, CA, USA
• (2004-Present) Professor and Chair, Department of Dermatology, UCSF, San Francisco, CA, USAand Department of Dermatology and Allergology, Juntendo University Graduate School of Medicine
• (2006-Present) Vice Director, Atopy (allergy) Research Center, Juntendo University Graduate School of Medicine

Research Interest

His research interest includes: Keratinizing and bullous disorders (including psoriasis), Hair disorders, Medical mycology, Atopic dermatitis, molecular genetics, regenerative medicine.

Scientific Activities


• (1993) Research Fellowship, Dermatology Foundation, USA
• (2000) Basic Medical Science-Shiseido award, Japanese Dermatological Association


• Japanese Dermatological Association (Delegate)
• Japanese Society for Investigative Dermatology (Councilor)
• Japanese Society for psoriasis research (Board of Directors)
• Japanese Society for Apheresis (Board of Directors)
• International Society for Apheresis (Board Member)
• Japanese Society for Medical Mycology (Councilor)
• Japanese Society of Allergy
• Japanese Society of Immunology
• Society for Hair Science Research (Board of Directors)
• American Academy of Dermatology (International Fellow)
• Tentative Instructor of Clinical Oncology, Japanese Board of Cancer Therapy


1. Hasegawa T, Sakamoto A, Wada A, Fukai T, Iida H, Ikeda S. Keratinocyte progenitor cells reside in human subcutaneous adipose tissue. PLoS One. 2015; 10(2): e0118402.doi:10.1371/journal.pone.0118402
2. Arima K, Ohta S, Takagi A, et al. Periostin contributes to epidermal hyperplasia in psoriasis common to atopic dermatitis. Allergol Int. 2015; 64: 41-48. doi:10.1016/j.alit.2014.06.001
3. Tsutsui-Takeuchi M, Ushio H, Fukuda M, et al. Roles of retinoic acid-inducible gene-I-like receptors (RLRs), Toll-like receptor (TLR) 3 and 2-5 oligoadenylate synthetase as viral recognition receptors on human mast cells in response to viral infection. Immunol Res. 2015; 61: 240-249. doi:10.1007/s12026-014-8617-x.
4. Yoshihara N, Ueno T, Takagi A, et al. The significant role of autophagy in the granular layer in normal skin differentiation and hair growth. Arch Dermatol Res. 2015; 307: 159-169. doi:10.1007/s00403-014-1508-0
5. Kiatsurayanon C, Niyonsaba F, Smithrithee R, et al. Host defense (Antimicrobial) peptide, human β-defensin-3, improves the function of the epithelial tight-junction barrier in human keratinocytes. J Invest Dermatol. 2014; 134: 2163-2173. doi:10.1038/jid.2014.143.
6. Oka A, Mabuchi T, Ikeda S, et al. IL12B and IL23R gene SNPs in Japanese psoriasis. Immunogenetics. 2013; 65: 823-828. doi:10.1007/s00251-013-0721-x
7. Haida Y, Ikeda S, Takagi A, et al. Association analysis of the HLA-C gene in Japanese alopecia areata. Immunogenetics. 2013; 65: 553-557.doi:10.1007/s00251-013-0703-z
8. Hirota T, Takahashi A, Kubo M, et al: Genome-wide association study identifies eight new susceptibility loci for atopic dermatitis in the Japanese population. Nat Genet. 2012; 44: 1222-6.doi:10.1038/ng.2438