Shabana Islam, MS, PhD
Scientific Support Specialist
Corning Life Sciences
Dr. Islam received her Masters and PhD degree(s) in Biochemistry from Aligarh Muslim University, India. Her doctoral work focused on structure-activity relationship of steroidal drug-development candidates. Prior to joining Corning, she worked as a Consultant at Eutropics Pharmaceuticals in MA supporting development of small molecule inhibitors of Bcl-2 family proteins for cancer research. Formerly, she has held Senior Research position at Childrens Hospital/Harvard Medical School in Boston, MA; Research Faculty and Postdoctoral Investigator positions at Case Western Reserve University, Cleveland, OH; and Postdoctoral student at the University of Kansas, Lawrence, KS. She has conducted research in the area of cell and molecular biology and has authored/co-authored several publications in peer reviewed journal articles. She has also developed web tools and protocols/scientific literatures for various applications (eg. cancer research, stem cells) and presented webinar which are posted on company website (Corning) that are linked to the cell culture products and resources. She is currently the Scientific Support Specialist at Corning Life Sciences.
Her research interests include: Cell culture-based research applications as well as stay current with new technology developments.
AWARDS AND HONORS
• (2003) Women in Science Award, MARC, FASEB Summer Research Conferences, NIH
• (1987-1988) Pre-Doctoral Fellowship from Jeddah, KSA; and AMU, India
• Doctoral Fellowship, Indian Council of Medical Research; AMU; and some support from Exchange Program, The University of Leeds, UK
• Women in Cell Biology
• Women Entrepreneurs in Science and Technology
• Society for Neuroscience
• American Association for the Advancement of Science
• Society of Biological Chemists
• The American Gastroenterological Association
• Massachusetts Academy of Sciences
• Gastroenterological Research Group
• The American Society for Cell Biology
1. Baffour-Awuah NY, Delemarre E, Fujiwara Y, et al. Characterization of expression in mice of a transgene containing 3.3 kb of the human lactase-phlorizin hydrolase (LPH) 5 flanking sequence. Dig Dis Sci. 2011; 56(1): 59-69.
2. Islam S, Loizides AM, Fialkovich JJ, Grand RJ, Montgomery RK. Developmental expression of Eph and ephrin family genes in mammalian small intestine. Dig Dis Sci. 2010; 55(9): 2478-2488. doi: 10.1007/s10620-009-1102-z
3. Burpee T, Mitchell P, Fishman D, et al. Intestinal ferroportin expression in pediatric Crohns disease. Inflamm Bowel Dis. 2010; 17(2): 524-531.
4. Islam S, Montgomery RK, Fialkovich JJ, Grand RJ. Developmental and regional expression and localization of mRNAs encoding proteins involved in RNA translocation. J Histochem Cytochem. 2005; 53(12): 1501-1509. doi: 10.1369/jhc.5A6655.2005
5. Abraham EG, Islam S, Srinivasan P, et al. Analysis of the Plasmodium and Anopheles transcriptional repertoire during ookinete development and midgut invasion. J Biol Chem. 2004; 279(7): 5573-5580. doi: 10.1074/jbc.M307582200
6. Islam S, Kermode T, Sultana D, et al. Expression profile of protein tyrosine kinase genes in human osteoarthritis chondrocytes. Osteoarthritis Cartilage. 2001; 9(8): 684-693. doi: 10.1053/joca.2001.0465
7. Islam S, Islam N, Kermode T, et al. Involvement of caspase-3 in epigallocatechin-3-gallate-mediated apoptosis of human chondrosarcoma cells. Biochem Biophys Res Commun. 2000; 270(3): 793-797. doi: 10.1006/bbrc.2000.2536
8. Ah-Kim H, Zhang X, Islam S, et al. Tumour necrosis factor alpha enhances the expression of hydroxyl lyase, cytoplasmic antiproteinase-2 and a dual specificity kinase TTK in human chondrocyte-like cells. Cytokine. 2000; 12(2): 142-150. doi: 10.1006/cyto.1999.0539
9. Pal R, Eaton MJ, Islam S, Hake-Frendscho M, Kumar KN, Michaelis EK. Immunocytochemical and in situ hybridization studies of the expression and distribution of three subunits of a complex with N-methyl-D-aspartate receptor-like properties. Neuroscience. 1999; 94(4): 1291-1311. doi: 10.1016/S0306-4522(99)00386-3
10. Quadri SA, Islam S, Qadri AN, Ahmad M. Aziridinyl steroid-induced lesions in DNA and apoptosis in promyelocytic leukemia cells. Biochem Mol Biol Int. 1997; 43(6): 1353-1365.
11. Bland KS, Takahashi K, Islam S, Michaelis ML. Effects of NCX1 antisense oligodeoxynucleotides on cardiac myocytes and primary neurons in culture. Ann N Y Acad Sci. 1996; 779: 119-120. doi: 10.1111/j.1749-6632.1996.tb44777.x
12. Takahashi K, Bland KS, Islam S, Michaelis ML. Effects of antisense oligonucleotides to the cardiac Na+/Ca2+ exchanger on cultured cardiac myocytes. Biochem Biophys Res Commun. 1995; 212(2): 524-530.
13. Qadri SA, Islam S, Ahmad M. Mutagenic activity of oxathiolane steroids: structural requirement for the genotoxic activity in Salmonella and E. coli. Mutat Res. 1992; 298(1): 53-60. doi: 10.1016/0165-1218(92)90028-X
14. Islam S, Ahmad M. Mutagenic activity of aziridinyl steroids and their mechanism of action in biological systems. Mutagenesis. 1991; 6(4): 271-278. doi: 10.1093/mutage/6.4.271
15. Islam S, Shafiullah, Ahmad M. Mutagenic activity of certain synthetic steroids: structural requirement for the mutagenic activity in Salmonella and E. coli. Mutat Res. 1991; 259(2): 177-187. doi: 10.1016/0165-1218(91)90051-M