Myriam N. Bouchlaka, PhD


Post Doctoral Fellow
Immunotherapy and Hematopoietic Stem Cell Transplant Research Group (Capitini)
University of Wisconsin-Madison
1111 Highland Ave, WIMR 4136
Madison, WI 53705, USA

Biography

EDUCATION

•(2011) PhD, Cellular and Molecular Biology, University of Nevada, Reno, School of Medicine
Advisor: William J. Murphy, PhD
Thesis: Cancer Immunotherapy: Limitations and Potential Strategies
•(2007) BS, Biology, University of Nevada, Reno, NV
Minor: Chemistry

Research Interest

Her research interests include: Cancer immunotherapy, inflammation mediated from immunotherapy, translational studies for bone marrow transplantation, GVHD biology, and trafficking of adoptive cellular therapies..

Scientific Activities

AWARDS

•(2014-2015) American Association of Immunologists (AAI) Career in Immunology Fellowship
•(2014) Caymans Women in Research Travel Grant for presenting an abstract at the American Association of Immunologists (AAI), Pittsburgh, PA
•(2010) University of Nevada Travel Award for presenting an abstract at the American Association of Immunologists (AAI), Baltimore, MD
•(2007-2011) Graduate Assistantship, University of Nevada, Reno, NV
•(2003-2007) Undergraduate Student Athlete Academic Scholarship, University of Nevada, Reno, NV
•( 2003-2006) Scholar Award for All Western Athletic Conference (WAC) Student Athlete

PROFESSIONAL MEMBERSHIP

•( 2014-Present) Trainee member, American Association of Immunologists (AAI)
•( 2014-Present) Trainee member, American Society of Hematology (ASH)
•(2014-Present) Inflammation Research Association (IRA)

Publications

1. Bouchlaka MN, Redelman D, Murphy WJ. Immunotherapy Following Hematopoietic Stem Cell Transplantation: Potential for Synergistic Effects. Immunotherapy. 2010; 2(3): 399-418. doi: 10.2217/imt.10.20.
2. Tietze JK, Wilkins DE, Bouchlaka MN, et al. Delineation of Antigen-Nonspecific CD8+ Memory T cells After Cancer Immunotherapy in Mice and Human. Blood. 2012; 119(13): 3073-3083. doi: 10.1182/blood-2011-07-369736.
3. Sun K, Hsiao HH, Bouchlaka M, et al. IFN-γ Receptor Deficient Donor T cells Mediate Protection from Graft-versus-Host Disease and Preserve Graft-versus-Tumor Responses After Allogeneic Bone Marrow Transplantation. J Immunol. 2012; 189(4):2033-42. doi: 10.4049/jimmunol.1102853.
4. Bouchlaka MN, Sckisel GD, Wilkins D, et al. Mechanical Disruption of Tumors by Iron Particles and Magnetic Field Application Results in Increased Anti-tumor Immune Responses. PLoS One. 2012; 7(10): e48049. doi: 10.1371/journal.pone.0048049.
5. Bouchlaka MN, Sckisel GD, Chen M, et al. Aging Predisposes to Acute Inflammatory Induced Pathology After Tumor Immunotherapy. J Exp Med. 2013; 210(11): 2223-2237. doi: 10.1084/jem.20131219.
6. Bouchlaka MN, Murphy WJ. Impact of Aging in Cancer Immunotherapy: The Importance of Using Accurate Preclinical Models. OncoImmunology. 2013; 2(12):e27186.
7. Alvarez M, Bouchlaka MN, Sckisel GD, Sungur CM, Chen M, Murphy WM. Increased Anti-tumor Effects using IL2 with anti-TGFβ Reveals Competition Between Mouse NK and CD8 T cells. J Immunol. 2014. doi: 10.4049/jimmunol.1400034.
8. Mirsoian A, Bouchlaka MN, Sckisel D, et al. Adiposity Induces Lethal Cytokine Storm After Systemic Administration of Stimulatory Immunotherapy Regimens in Aged Mice. J Exp Med. 2014.