Mustafa Sahin, MD

Associate Professor
Department of Endocrinology and Metabolism
Ankara University School of Medicine
İbni Sina Hastanesi Ek Bina M-blok Kat:1
Sıhhıye/Ankara 06100,Turkey

Biography

EDUCATIONAL QUALIFICATIONS

• MD, Medical Faculty (English), Hacettepe University (1997)
• Speciality, Internal Medicine, Ankara University (2003)
• Speciality, Endocrinology and Metabolic Diseases, Baskent University (2006)

PROFESSIONAL EXPERIENCES

• Fellow, Ankara University Medical Faculty Internal Medicine Department (1998-2003)
• Fellow, Başkent Üniversitesi Medical Faculty Endocrinology and Metabolism Diseases Department (2003-2006)
• Specialist, Gülhane Üniversitesi Medical Faculty Endokrinoloji ve Metabolizma Hastalıkları Bilim Dalı (Army job) (2007-2008)
• Specialist Sağlık Baskanlığı Avukat Cengiz Gökçek State Hospital (2007)
• Postdoctoral Fellow, Mayo Clinic Department of Endocrinology and Metabolism, USA (2001-2001)
• Associate Professor, Diskapi Research Hospital Department of Endocrinology docrinology and Metabolism, Turkey (2010-2011)
• Associate Professor, Ankara University Department of Endocrinology docrinology and Metabolism, Turkey (2011-Present)

Research Interest

His research interests include: Endocrine Emergencies, Endocrinology in intensive care and Preoperative care.

Scientific Activities

MEMBERSHİPS

• Society of Endocrinology and Metabolism of Turkey (TEMD) (2003)
• European Thyroid Association (ETA) (2008)
• European Endocrinology Association

Publications

1. Keven K, Sahin M, Kutlay S, et al. Immunoglobulin deficiency in kidney allograft recipients: comparative effects of mycophenolate mofetil and azathioprine. Transpl Infect Dis. 2003; 5: 181-186. doi: 10.1111/j.1399-3062.2003.00035.x
2. Kamel N, Corapcioglu D, Sahin M, Gursoy A, Kucuk O, Aras G. I-131 therapy for thyroglobulin positive patients without anatomical evidence of persistent disease. J Endocrinol Invest. 2004; 27: 949-953. doi: 10.1007/BF03347538
3. Sahin M, Tutuncu N, Guvener ND. Autoimmune hypoglycemia in a type 2 diabetic patient with anti-insulin and insulin receptor antibodies. Diabetes Care. 2004; 27: 1246-1247.
4. Gregory Powell J, Wang X, Allard BL, et al. The PAX8/PPARgamma fusion oncoprotein transforms immortalized human thyrocytes through a mechanism probably involving wild-type PPARgamma inhibition. Oncogene. 2004; 23: 3634-3641.
5. Sahin M, Allard BL, Yates M, et al. PPARgamma staining as a surrogate for PAX8/PPARgamma fusion oncogene expression in follicular neoplasms: clinicopathological correlation and histopathological diagnostic value. J Clin Endocrinol Metab. 2005; 90: 463-468. doi: 10.1210/jc.2004-1203#sthash.GVwOvByF.dpuf
6. Sahin M, Guvener ND, Ozer F, et al. Thyroid Cancer in Hyperthyroidism: Incidence Rates and Value of Ultrasound-Guided Fine-Needle Aspiration Biopsy in This Patient Group. J Endocrinol Invest. 2005; 28(9): 815-818.
7. Sahin M, Bakiner O, Ertugrul D, Guvener ND. Creatine kinase elevation in a patient taking rosiglitazone. Diabet Med. 2005; 22: 1624-1625.
8. Sahin M, Yilmaz H, Guvener ND. A possible case of gynecomastia with fluoxetine. Ann Pharmacother. 2005; 39(7-8): 1369.
9. Sahin M, Erdogan MF, Erdogan G. Cytotoxic T lymphocyte-associated molecule-4 polymorphisms in Turkish Graves disease patients and association with probability of remission after antithyroid therapy. Eur J Intern Med. 2005; 16: 352-355.
10. Sahin M, Gursoy A, Bascil Tutuncu ve N N. Demirag G. Prevalence and prediction of malignancy in cytologically indeterminate thyroid nodules. Clin. Endocrino. 2006; 65: 514-518.
11. Sahin M, Tutuncu NB, Kanbay M, Guvener ND. Case Report: Surgery for Hyperthyroidism in Down Syndrome. Mt Sinai J Med. 2006; 73(5): 784-786.
12. Gursoy A, Ertugrul DT, Pamuk B, et al. Mean platelet volume in patients with polycystic ovary disease, Platelets.
2006; 17: 505-506.
13. Gursoy A, Sahin M, Ertugrul DT, et al. Familial dilated cardiomyopathy hypergonadotrophic hypogonadism associated with thyroid hemiagenesis. Am. J. Med. Genet. A. 2006; 140: 895-896. doi: 10.1002/ajmg.a.31161
14. Tanaci N, Ertugrul DT, Sahin M, et al. Postprandial lipemia as a risk factor for cardiovascular disease in patients with hypothyroidism. Endocrine. 2006; 29: 451-456. doi: 10.1385/ENDO:29:3:451
15. Ertugrul DT, Gursoy A, Yucel M, et al. Effects of raloxifene on platelet functions in patients with postmenopausal osteoporosis. Platelets. 2006; 17: 351-353. doi: 10.1080/09537100600746649
16. Gursoy A, Kulaksizoglu M, Sahin M, et al. Severe hypertriglyceridemia-induced pancreatitis during pregnancy. J. Natl. Med. Assoc. 2006; 98: 655-657.
17. Sahin M, Sengul A, Berki Z, Tutuncu NB, Guvener ND. Ultrasound-guided fine-needle aspiration biopsy and ultrasonographic features of infracentimetric nodules in patients with nodular goiter: correlation with pathological findings. Endocr Pathol. 2006; 17: 67-74.
18. Sahin M, Ertugrul D, Tutuncu NB, Guvener ND. Effects of metformin or rosiglitazone on serum concentrations of homocysteine, folate, and vitamin B12 in patients with type 2 diabetes mellitus. J Diabetes Complications. 2007; 21(2): 118-123. doi: 10.1016/j.jdiacomp.2005.10.005
19. Sahin M, Yilmaz H, Gursoy A, Demirel AN, Tutuncu NB, Guvener ND. Gynaecomastia in a man and hyperoestrogenism in a woman due to ingestion of nettle (Urtica dioica). N Z Med J. 2007; 120: U2803.
20. Sahin M, Tanaci N, Yucel M, Tutuncu NB, Guvener N. The effect of single-dose orlistat on postprandial serum glucose, insulin and glucagon-like peptide-1 levels in nondiabetic obese patients. Clin Endocrinol (Oxf). 2007; 67: 346-350.
21. Gursoy A, Ertugrul DT, Sahin M, Bascil Tutuncu N, Nar ve NA. Guvener Demirag, Needle-Free Delivery of Lidocaine for Reducing the Pain Associated with the Fine-Needle Aspiration Biopsy of Thyroid Nodules: Time Saving and Efficacious Procedure. Thyroid. 2007; 17: 317-321.
22. Gursoy A, Ertugrul DT, Sahin M, et al. The Analgesic Efficacy of Lidocaine/Prilocaine (EMLA) Cream during the Fine-Needle Aspiration Biopsy of Thyroid Nodules. Clin. Endocrinol. 2007; 66: 691-694.
23. Yilmaz H, Gursoy A, Sahin M, Demirag N. Comparison of insulin monotherapy and combination therapy with insulin and metformin or insulin and rosiglitazone or insulin and acarbose in type 2 diabetes. Acta Diabetol. 2007; 44: 187-192.
24. Taslipinar A, Kebapcilar L, Kutlu M, et al. HDR syndrome (hypoparathyroidism, sensorineural deafness and renal disease) accompanied by renal tubular acidosis and endocrine abnormalities. Intern Med. 2008; 47: 1003-1007. doi: 10.2169/internalmedicine.47.0917
25. Uysal AR, Sahin M, Gürsoy A, Güllü S. Vitamin D receptor gene polymorphism and osteoporosis in the Turkish population, Genet Test. 2008; 12: 591-594.
26. Sahin M, Karatas M, Sahin M, et al. High prevalence of neuropathy in patients with impaired 60-minute oral glucose tolerance test but normal fasting and 120-minute glucose levels. Minerva Endocrinol. 2008; 33: 289-296.
27. Erdal M, Sahin M, Saglam K, et al. Increased serum chitotriosidase activity following restoration of euthyroidism in patients with subclinical hypothyroidism. Intern Med. 2008; 47: 1309-1314.
28. Erdal M, Sahin M, Hasimi A, Uckaya G, Kutlu M, Saglam K. Trace element levels in hashimoto thyroiditis patients with subclinical hypothyroidism. Biol Trace Elem Res. 2008; 123: 1-7.
29. Demirer AN, Kemal Y, Gursoy A, Sahin M, Tutuncu NB. Clinicopathological characteristics of thyroid cancer in patients on dialysis for end-stage renal disease. Thyroid. 2008; 18: 45-50.
30. Sahin M, Tanaci N, Yucel M, et al. Acute effects of orlistat on postprandial serum leptin levels in nondiabetic obese patients. Minerva Endocrinol. 2008; 33: 169-173.
31. Ozkaya M, Yuzbasioglu MF, Koruk I, et al. Preoperative detection of insulinomas: two case reports. Cases J. 2008; 29: 362. doi: 10.1186/1757-1626-1-362
32. Sahin M, Kebapcilar L, Taslipinar A, et al. Comparison of 1 mg and 2 mg overnight dexamethasone suppression tests for the screening of Cushings syndrome in obese patients. Intern Med. 2009; 48: 33-39. doi: 10.2169/internalmedicine.48.1234
33. Ozkaya M, Sahin M, Cakal E, Gisi K, Bilge F, Kilinc M. Selenium Levels in First-Degree Relatives of Diabetic Patients. Biol Trace Elem Res. 2009; 128: 144-151. doi: 10.1007/s12011-008-8263-z
34. Taslipinar A, Bolu E, Kebapcilar L, Sahin M, Uckaya G, Kutlu M. Insulin-like growth factor-1 is essential to the increased mortality caused by excess growth hormone: a case of thyroid cancer and non-Hodgkins lymphoma in a patient with pituitary acromegaly. Med Oncol. 2009; 26: 62-66. doi: 10.1007/s12032-008-9084-9
35. Sahin M, Gursoy A, Erdogan MF, Cytotoxic T. lymphocyte-associated molecule-4 polymorphism in Turkish patients with Hashimoto thyroiditis. Int J Immunogenet. 2009; 36: 103-106.
36. Bulucu F, Oca R, Karadurmus N, et al. Effects of N-Acetylcysteine, deferoxamine and selenium on doxorubicin induced hepatotoxicity. Biological Trace Element Research. 2009; 132(1-3): 184-196.
37. Sahin M, Sade LE, Tutuncu NB, et al. Systolic Pulmonary Artery Pressure and Echocardiographic Measurements in Patients with Euthyroid Hashimoto Thyroiditis. J. Endocrinol. Invest. 2009; 32(6): 530-532. doi: 10.3275/6134
38. Yazici M, Sahin M, Bolu E, et al. Prediction of testosterone response to human chorionic gonadotrophin in idiopathic hypogonadotropic hypogonadism patients. J Natl Med Assoc. 2009; 101: 71-76.
39. Sahin M, Delibasi T. Possible effects of androgens on Islet Cell Functions. Med Hypotheses. 2009; 72: 711-712. doi: 10.1016/j.mehy.2008.12.044
40. Ertugrul DT, Gursoy A, Sahin M, et al. Evaluation of brain natriuretic peptide levels in hyperthyroidism and hypothyroidism. J Natl Med Assoc. 2008; 100: 401-405.
41. Yazici M, Sahin M, Bolu E, et al. Evaluation of breast enlargement in young males and factors associated with gynecomastia and pseudogynecomastia. Ir J Med Sci. 2010; 179(4): 575-583. doi: 10.1007/s11845-009-0345-1
42. Koc B, Bulucu F, Karadurmus N, Sahin M. Lower leptin levels in young non-obese male smokers than non-smokers. Upsala Journal of Medical Sciences. 2009; 114(3): 165-169. doi: 10.1080/03009730902761631
43. Ozkaya M, Sahin M, Cakal E, et al. Visfatin plasma concentrations in patients with hyperthyroidism and hypothyroidism before and after control of thyroid function. J. Endocrinol. Invest. 2009; 32(5): 435-439. doi: 10.3275/6296
44. Altintas ND, Sahin M. Letter to Swaminathan entitled Search for secondary osteoporosis: are Z scores useful predictors? Postgraduate Medical journal. 2009.
45. Yuzbasioglu, MF, Ozkaya M, Sahin M, et al. Fine Needle Aspiration Cytology and Ziehl-Nielsen Stain in Thyroid Nodules Associated with Active Pulmonary Tuberculosis. Acta Cytologica. 2003; 53(5): 604-605.
46. Sahin M, Toprak SK, Altintas ND. Should Women With Abnormal Serum Thyroid Stimulating Hormone Undergo Screening for Anemia? Archives of Pathology and Laboratory Medicine. 2009; 133(8): 1188.
47. Yilmaz H, Tütüncü NB, Sahin M. Two-year follow-up of thirty-two non-functional benign adrenal incidentalomas. Endocrinol Invest. 2009; 32(11): 913-916. doi: 10.1007/BF03345772
48. Pekcici R, Kavlakoglu B, Yilmaz S, Sahin M, Delibasi T. Effects of lead on thyroid functions in lead-exposed workers. Central European Journal of Medicine. 2010; 5(2): 215-218.
49. Ozsari L, Boyunaga H, Karadurmus N, et al. Comparison of lymphomononuclear cell energy metabolism between healthy, impaired glucose intolerance and type 2 diabetes mellitus patients. Endocrine. 2010; 37(1): 135-139.
50. Corapcioglu D, Sahin M, Emral R, Celebi ZK, Sener O, Gedik VT. Association of the G894T polymorphism of the endothelial nitric oxide synthase gene with diabetic foot syndrome foot ulcer, diabetic complications, and comorbid vascular diseases: a Turkish case-control study. Genet Test Mol Biomarkers. 2010; 14(4): 483-488.
51. Karadurmus N, Sahin M, Tasci C, et al. Potential benefits of hyperbaric oxygen therapy on atherosclerosis and glycaemic control in patients with diabetic foot. Endokrynol Pol. 2010; 61(3): 275-279.
52. Kebapcilar L, Comlekci A, Tuncel P, et al. Effect of levothyroxine replacement therapy on paraoxonase-1 and carotid intima-media thickness in subclinical hypothyroidism. Med Sci Monit. 2010; 16(1): CR41-CR47.
53. Candemir B, Ertas FS, Kaya CT, et al. Association between antibodies against calcifying nanoparticles and mitral annular calcification. J Heart Valve Dis. 2010; 19(6):745-752.
54. Tulunay Kaya C, Sinan Ertas F, Hasan T, et al. Anticalcifying nanoparticle antibody titer is an independent risk factor for coronary artery calcification. Coron Artery Dis. 2011; 22(6): 394-400.
55. Yasar HY, Ertuğrul O, Ertuğrul B, Ertuğrul D, Sahin M. Insulin resistance in nodular thyroid disease. Endocr Res. 2011; 36(4): 167-174.
56. Bozkurt NC, Cakal E, Sahin M, Ozkaya EC, Firat H, Delibasi T. The relation of serum 25-hydroxyvitamin-D levels with severity of obstructive sleep apnea and glucose metabolism abnormalities. Endocrine. 2012; 41(3): 518-525. doi: 10.1007/s12020-012-9595-1
57. Sahin M, Dilli A, Karbek B, et al. Unusual cause of primary amenorrhea due to kissing internal carotid arteries. Pituitary. 2012; 15: 258-259.
58. Yilmaz H, Kaya M, Sahin M, Delibasi T. Is vitamin D status a predictor glycaemic regulation and cardiac complication in type 2 diabetes mellitus patients? Diabetes Metab. Syndr. 2012; 6(1): 28-31.
59. Cakal E, Cakir E, Dilli A, et al. Parathyroid adenoma screening efficacies of different imaging tools and factors affecting the success rates. Clin Imaging. 2012; 36(6): 688-694. doi: 10.1016/j.clinimag.2012.01.038
60. Gungunes A, Sahin M, Gultekin SS, et al. Nonadenomatous nonencapsulated thymic parathyroid tissue concomitant with primary hyperparathyroidism due to ectopic parathyroid adenoma. Arq Bras Endocrinol Metabol. 2013; 57(9): 739-742.
61. Topaloglu O, Arslan MS, Turak O, et al. Three noninvasive methods in the evaluation of subclinical cardiovascular disease in patients with acromegaly: epicardial fat thickness, aortic stiffness and serum cell adhesion molecules. Clin Endocrinol (Oxf). 2014; 80(5): 726-734. doi: 10.1111/cen.12356
62. Karbek B, Cakal E, Cakir E, et al. Cardiovascular risk factors, carotid artery intima media thickness, and HSCRP levels in patients with impaired glucose metabolism. Minerva Endocrinol. 2013; 38(3): 297-304.
63. Sayki Arslan M, Sahin M, Topaloglu O, et al. Hyperprolactinaemia associated with increased thyroid volume and autoimmune thyroiditis in patients with prolactinoma. Clin Endocrinol (Oxf). 2013; 79(6): 882-886.
64. Bozkurt NC, Karbek B, Ucan B, et al. The association between severity of vitamin D deficiency and Hashimotos thyroiditis. Endocr Pract. 2013; 19(3): 479-484. doi: 10.4158/EP12376.OR
65. Cakir E, Ozbek M, Sahin M, et al. Heart type fatty acid binding protein response and subsequent development of atherosclerosis in insulin resistant polycystic ovary syndrome patients. J Ovarian Res. 2012; 5(1): 45. doi: 10.1186/1757-2215-5-45
66. Cakir E, Sahin M, Topaloglu O, et al. The relationship between LH and thyroid volume in patients with PCOS. J Ovarian Res. 2012; 5(1): 43.
67. Cakir E, Sahin M, Cakal E, Ozbek M, Delibasi T. Medical hypothesis: can gonadotropins influence thyroid volume in women with PCOS? Thyroid Res. 2012; 5(1): 17.
68. Sahin M, Taslipinar A, Kebapcilar L, et al. Low vitamin D3 levels in euthyroid hashimoto thyroiditis. International Medical Journal. 2012.
69. Unsal IO, Ginis Z, Pinarli FA, et al. Comparison of Therapeutic Characteristics of Islet Cell Transplantation Simultaneous with Pancreatic Mesenchymal Stem Cell Transplantation in Rats with Type 1 Diabetes Mellitus. Stem Cell Rev. 2015; 11(3): 526-532. doi: 10.1007/s12015-014-9563-7.
70. Şahin M, Çakal E, Özbek M, et al. Elastography in the differential diagnosis of thyroid nodules in Hashimoto thyroiditis. Med Oncol. 2014; 31(8): 97. doi: 10.1007/s12032-014-0097-2
71. Gungunes A, Ozbek M, Ginis Z, et al. Serum nesfatin-1 levels in overt and subclinical hyperthyroidism. Minerva Endocrinol. 2014; 39(3): 209-214.
72. Gungunes A, Sahin M, Demirci T, et al. Cushings syndrome in type 2 diabetes patients with poor glycemic control. Endocrine. 2014; 47(3): 895-900. doi: 10.1007/s12020-014-0260-8
73. Arslan MS, Topaloglu O, Sahin M, et al. Preclinical atherosclerosis in patients with prolactinoma. Endocr Pract. 2014; 20(5): 447-451. doi: 10.4158/EP13173.OR
74. Topaloglu O, Arslan MS, Karakose M, et al. Is There Any Association Between Thrombosis and Tissue Factor Pathway Inhibitor Levels in Patients With Vitamin D Deficiency? Clin Appl Thromb Hemost. 2015; 21(5): 428-433.
75. Aydogan Bİ, Sahin M. Adipocytokines in thyroid dysfunction. ISRN Inflamm. 2013; 2013: 646271.
76. Asik M, Sahin S, Temiz A, et al. Evaluation of epicardial fat tissue thickness in patients with primary hyperparathyroidism. Endocr Pract. 2014; 20(1): 26-32.
77. Sahin M, Uçan B, Giniş Z, et al. Vitamin D3 levels and insulin resistance in papillary thyroid cancer patients. Med Oncol. 2013; 30(2): 589. doi: 10.1007/s12032-013-0589-5
78. Karaköse M, Cakal E, Topaloğlu O, et al. Is there a link between polycystic ovary syndrome and non-thyroidal illness syndrome? J Turk Ger Gynecol Assoc. 2013; 14(4): 216-220.
79. Delibaşı T, Arslan MS, Çakal E, et al. Hyperprolactinemia has no effect on plasma ghrelin levels in patients with prolactinoma. J Turk Ger Gynecol Assoc. 2015; 16(2): 86-90.
80. Arslan MS, Ekiz F, Deveci M, et al. The relationship between cytotoxin-associated gene A positive Helicobacter pylori infection and autoimmune thyroid disease. Endocr Res. 2015; 13: 1-4.
81. Karakose M, Karbek B, Sahin M, et al. The association of autoimmune thyroiditis and non-functional adrenal incidentalomas with insulin resistance. Arch Endocrinol Metab. 2015; 59(1): 42-46. doi: 10.1590/2359-3997000000008.
82. Ayvaz G, Keskin L, Akin F, et al. Real-life safety and efficacy of vildagliptin as add-on to metformin in patients with type 2 diabetes in Turkey–GALATA study. Curr Med Res Opin. 2015; 31(4): 623-632.
83. Arslan MS, Topaloglu O, Ucan B, et al. Isolated vitamin D deficiency is not associated with nonthyroidal illness syndrome, but with thyroid autoimmunity. Scientific World Journal. 2015; 2015: 239815. doi: 10.1155/2015/239815
84. Ucan B, Delibasi T, Cakal E, et al. Papillary thyroid cancer case masked by subacute thyroiditis. Arq Bras Endocrinol Metabol. 2014; 58(8): 851-854.
85. Topaloglu O, Ucan B, Demirci T, et al. Solitary fibrous tumor of neck mimicking cold thyroid nodule in 99m tc thyroid scintigraphy. Case Rep Endocrinol. 2013; 2013: 805745. doi: 10.1155/2013/805745
86. Yilmaz H, Ucan B, Sayki M, et al. Usefulness of the neutrophil-to-lymphocyte ratio to prediction of type 2 diabetes mellitus in morbid obesity. Diabetes Metab Syndr. 2014.
87. Altıntas ND, Sahin M. The value of elastosonography in evaluation of Thyroid Nodules. Recent Patents on Medical İmaging. 2013; 3(2): 1-4.
a. Cakal M, Sahin M, Unsal I, et al. Elastography in the differential diagnosis of thyroid nodules. Ultrasonic Imaging. 2015; 37(3): 251-257. doi: 10.1177/0161734614547542.
88. Gungunes A, Unsal I, Sahin M, et al. A case of adrenocortical carcinoma with gynecomastia and subclinical cushings syndrome. Formos J Endocrin Metab. 2012; 3(2): 35-39.
89. Eroglu M, Erbag G, Turkon H, et al. Are small adrenal incidentalomas solely a radiological finding? Exp Clin Endocrinol Diabetes. 2015; 123(8): 451-454. doi: 10.1055/s-0035-1555890