Masahiro Kohzuki, MD, PhD

Associate Dean
Professor and Chairman
Department of Internal Medicine and Rehabilitation Science, Disability Sciences
Tohoku University Graduate School of Medicine
Chairman of the Center of Rehabilitation Medicine
Tohoku University Hospital
Japan

Biography

Prof. Masahiro Kohzuki is the Associate Dean of Tohoku University Graduate School of Medicine and the Director of Rehabilitation Center at Tohoku University Hospital, and Chairman and Professor of Internal Medicine & Rehabilitation Science in Tohoku University Graduate School of Medicine.
He is the first physiatrist who succeeded in pulmonary rehabilitation to the lung transplant patient from a brain-dead donor in Japan. He and Dr. Kurosawa published an article of Visualization of airflow limitation in emphysematous lung. in New England Journal of Medicine (N Eng J Med 350: 1036, 2004).
He is a Chairman of the Board of Directors of Japanese Society of Renal Rehabilitation and one of the Directors of several association including Japanese Association of Rehabilitation Medicine and Japanese Association of Cardiac Rehabilitation.
He was a President of Directors of Rehabilitation Centers at National University Hospitals in Japan.
He is the Editor-in-Chief of Open Journal of Therapy and Rehabilitation and Editorial Board of several international journals.
He is the visiting professor of Tianjin Medical Univerisity (China), Northeast Normal University (China), Woosong University (Korea), Masaryk University (Czech).

Research Interest

His research interests include: Pulmonary rehabilitation.

Scientific Activities

AWARDS AND HONORS

• (2003) Encouragement Award, Japanese Association of Rehabilitation Medicine
• (2004) Best Paper Award, Japanese Association of Rehabilitation Medicine
• (2007) President Award, Japanese Society of Stoma and Continence Rehabilitation
• (2007, 2010) Award of the Head of Tohoku University Hospital

MEMBERSHIPS IN INTERNATIONAL PROFESSIONAL SOCIETIES

• International Society of Physical and Rehabilitation Medicine
• Asia-Oceania Society of Physical and Rehabilitation Medicine
• American Society of Physical Medicine and Rehabilitation
• International Society of Hypertension
• American College of Sports Medicine
• American Heart Association

Publications

1. Yasujima M, Abe K, Kohzuki M, et al. Atrial natriuretic factor inhibits the hypertension induced by chronic infusion of norepinephrine in conscious rats. Circ Res. 1985; 57: 470-474. doi: 10.1161/01.RES.57.3.470
2. Kohzuki M, Abe K, Yasujima M, et al. Chronic effect of a synthetic atrial natriuretic factor on the development of hypertension in young spontaneously hypertensive rats. J Hypertens. 1986; 4 (Suppl 3): 487-489.
3. Kasai Y, Abe K, Yasujima M, et al. The augmented hypotensive response to a synthetic atrial natriuretic factor in SHR. J Hypertens. 1986; 4(suppl 3): 325-327.
4. Sato M, Abe K, Takeuchi K, et al. Atrial natriuretic factor and cyclic guanosine monophosphate in vascular smooth muscle. Hypertension. 1986; 8: 762-771. doi: 10.1161/01.HYP.8.9.762
5. Sato M, Abe K, Takeuchi K, et al. Atrial natriuretic polypeptide and cyclic GMP synthesis in vascular smooth muscle, glomerular mesangial and renal collecting tubule cell in culture. J Hypertens. 1986; 4(Suppl 6): 576-587.
6. Tanno M, Abe K, Yasujima M, et al. The prostaglandin (PG)-thromboxane (TX) system in the development of hypertension in young SHR. J Hypertens. 1986; 4(Suppl 3): 395-397.
7. Tsunoda K, Abe K, Omata K, et al. Hypotensive and natriuretic effects of nifedipine in essential hypertension: Role of renal kallikrein-kinin-prostaglandin and renin-angiotensin-aldosterone systems. J Clin Hypertens. 1986; 2: 263-270.
8. Yasujima M, Abe K, Tanno M, et al. Effects of ouabain on blood pressure regulation in rats. J Hypertens. 1986; 4: 597-601.
9. Yasujima M, Abe K, Kohzuki M, et al. Effect of atrial natriuretic factor on angiotensin II-induced hypertension in rats. Hypertension. 1986; 8: 748-753. doi: 10.1161/01.HYP.8.9.748
10. Yasujima M, Abe K, Tanno M, et al. Effects of sodium and angiotensin II on urinary active and inactive kallikrein in rats. J Hypertens. 1986; 4: 13-18.
11. Yasujima M, Abe K, Kohzuki M, et al. Antihypertensive effect of synthetic atrial natriuretic factor in vasopressin-infused rats. Jap Circ J. 1986; 50: 1185-1190. doi: 10.1253/jcj.50.1185
12. Yasujima M, Abe K, Kohzuki M, et al. Chronic effect of synthetic atrial natriuretic factor in rats made hypertensive by sustained infusion of vasopressin. Biologically Active Atrial Peptides. 1987; 1: 519-523.
13. Kasai Y, Abe K, Yasujima M, Tanno M, Kohzuki M, Yoshinaga K. Acute effects of synthetic atrial natriuretic factor in anesthetized spontaneously hypertensive rats and DOCA-salt hypertensive rats. Biologically Active Atrial Peptides. American Society of hypertension Symposium Series. 1987; 1: 376-379.
14. Sato M, Abe K, Takeuchi K, et al. Inhibitory effect of sulindac on prostaglandin synthesis in cultured renal and vascular cells. Agents and Actions. 1987; 22: 370-378.
5. Yasujima M, Abe K, Tanno M, et al. Long-term effects of aldosterone on kallikrein, prostaglandin E2 and sodium in rats. Tohoku J Exp Med. 1987; 152: 351-362. doi: 10.1620/tjem.152.351
16. Yasujima M, Abe K, Tanno M, et al. Role of the prostaglandin-thromboxane system in the development and maintenance of spontaneously hypertension in the rats. Agents and Actions. 1987; 22(Suppl 1): 133-138.
17. Yasujima M, Abe K, Tanno M, et al. No evidence on significant roles of the prostaglandin thromboxane and kallikrein-kinin system in the antihypertensive effect of MK421 in rats made hypertensive by norepinephrine or vasopressin. Clin Exp Hypertens. 1987; A9: 323-328.
18. Kohzuki M, Abe K, Yasujima M, et al. A case of systemic lupus erythematosus complicated with vascular occlusion in the aorta and renal artery. Jap J Med. 1987; 76: 713-714.
19. Yasujima M, Abe K, Tanno M, et al. Renal kallikrein activity in spontaneously hypertensive rats. J Hypertens. 1987; 5: 687-692.
20. Yasujima M, Abe K, Tanno M, et al. Effects of angiotensin converting enzyme inhibitors MK421, SA446 and captopril on renal prostaglandin E and kinins in conscious normotensive rats. Clin Exp Hypertens. 1987; A9: 401-404.
21. Kohzuki M, Hodsman GP, Harrison RW, Johnston CI. Attenuated renal response to atrial natriuretic peptide infusion in rats with heart failure. Clin Exp Pharmacol Physiol. 1988; 15: 323-326.
22. Hodsman GP, Kohzuki M, Howes LG, Sumithran E, Tsunoda K, Johnston CI. Neurohumoral responses to chronic myocardial infarction in rats. Circulation. 1988; 78: 376-381. doi: 10.1161/01.CIR.78.2.376
23. Johnston CI, Mendelsohn FAO, Cubela R, Jackson B, Kohzuki M, Fabris B. Inhibition of angiotensin converting enzyme (ACE) in plasma and tissues: studies ex vivo after administration of ACE inhibitors. J Hypertens. 1988; 6(Suppl 3): 17-22.
24. Johnston CI, Jackson B, Hodsman GP, Phillips P, Kohzuki M. Hypertension and renal function. J Nephrology (ROC). 1988; 151-153.
25. Kudo k, Abe K, Chiba S, et al. Role of thromboxane A2 in the hypotensive effect of captopril in essential hypertension. Hypertension. 1988; 11: 147-152. doi: 10.1161/01.HYP.11.2.147
26. Sato K, Abe K, Seino M, et al. Renal vein plasma renin activity in patients with unilateral renovascular hypertension. Jpn Circ J. 1988; 52: 431-436.
27. Yasujima M, Abe K, Kohzuki M, et al. Chronic effects of synthetic atrial natriuretic factor in mineralocorticoid hypertension in rats. Advance in Atrial Peptide Research. 1988; 2: 530-533.
28. Yasujima M, Abe K, Kanazawa M, et al. Effects of chronically administered atrial natriuretic factor in aldosterone-infused hypertensive rats. Jpn Circ J. 1988; 52: 1446-1449.
29. Johnston CI, Jackson B, Cubela R, Sivell D, Kohzuki M. Pharmacokinetics of angiotensin converting enzyme inhibitors in plasma and tissue using radio-inhibitor binding and displacement assays. Adv Exp Med Biol. 1989; 247: 29-34. doi: 10.1007/978-1-4615-9543-4_5
30. Johnston CI, Kohzuki M. Angiotensin converting enzyme: localization, regulation and inhibition. in Current Advances in Angiotensin Converting Enzyme Inhibitor. In: Sever P, MacGregor G, eds. Churchill-Livingstone, London. 1989; 3-7.
31. Johnston CI, Kohzuki M, Phillips P, Hodsman GP. Drug effects and atrial natriuretic peptide in experimental cardiac failure. Advances in Atrial Peptide Research. 1989; 3: 121-129.
32. Kohzuki M, Hodsman GP, Johnston CI. Attenuated response to atrial natriuretic peptide in rats with myocardial infarction. Am J Physiol. 1989; 256: H533-H538.
33. Kohzuki M, Hodsman GP, Harrison RW, Patrick W, Johnston CI. Attenuated renal and hypotensive responses to atrial natriuretic peptide infusion and changes in cyclic GMP in rats with heart failure. J Cardiovasc Pharmacol. 1989; 13 (Suppl 6): 43-46.
34. Kanazawa M, Abe K, Yasujima M, et al. Role of renal kallikrein in the regulation of blood pressure in the rat remnant kidney model of chronic renal failure. In: Kinins V, (Part B), Abe K, Moriya H, Fujii S, eds. Plenum Publishing Corporation, New York. 1989; 121-125.
35. Johnston CI, Hodsman PG, Kohzuki M, Casley DJ, Fabris B, Phillips PA. Interaction between atrial natriuretic peptide (ANP) and the renin-angiotensin system: endogenous antagonists. Am J Med. 1989; 87: 24-28.
36. Kanazawa M, Abe K, Yasujima M, et al. Role of renal kallikrein in the increased fractional sodium excretion in the rat remnant kidney model of chronic renal remnant kidney model of chronic renal failure. In: Kinins V, (Part B), Abe K, Moriya H, Fujii S, eds. Plenum Publishing Corporation, New York. 1989; 449-454.
37. Kohzuki M, Chai SY, Casley DJ, Rogerson F, Johnston CI, Mendelsohn FAO. Endothelin receptors in rat adrenal gland visualized by quantitative autoradiography. Clin Exp Pharmacol Physiol. 1989; 16: 239-242.
38. Kohzuki M, Johnston CI, Chai SY, Casley DJ, Mendelsohn FAO. Localization of endothelin receptors in rat kidney. Eur J Pharmacol. 1989; 160: 193-194.
39. Yasujima M, Abe K, Kanazawa M, et al. Effects of antihypertensive drugs on renal function and atrial natriuretic polypeptide in spontaneously hypertensive rats with renal ablation. Tohoku J Exp Med. 1989; 158: 85-94. doi: 10.1620/tjem.158.85
40. Chai SY, Sakaguchi K, Kohzuki M, Jackson B, Johnston CI, Mendelsohn FAO. Inhibition of ACE by using autoradiography. In: Sever P, MacGregor G, eds. In Current Advances in Angiotensin Converting Enzyme Inhibitor. Churchill-Livingstone, London. 1989; 199-202.
41. Howes LG, Hodsman GP, Maccarrone C, Kohzuki M, Johnston CI. Cardiac 3,4-dihydroxyphenylethylene glycol (DHPG) and catecholamine levels in a rat model of left ventricular failure. J Cardiovasc Pharmacol. 1989; 13: 348-352.
42. Kohzuki M, Abe K, Yasujima M, et al. Acute and chronic effects of synthetic rat atrial natriuretic factor on blood pressure and sodium excretion in spontaneously hypertensive rats. Tohoku J Exp Med. 1989; 157: 279-288.
43. Kohzuki M, Abe K, Yasujima M, et al. Blood pressure and renal response to synthetic rat atrial natriuretic factor in deoxycorticosterone acetate-salt hypertension. Tohoku J Exp Med. 1989; 157: 301-311. doi: 10.1620/tjem.157.301
44. Fabris B, Jackson B, Kohzuki M, Perich R, Johnston CI. Increased cardiac angiotensin-converting enzyme in rats with chronic heart failure. Clin Exp Pharmacol Physiol. 1990; 17: 309-314.
45. Yasujima M, Abe K, Kanazawa M, et al. Chronic effects of synthetic endothelin on blood pressure and sodium excretion in rats. Am J Hypertens. 1990; 3: 635-637. doi: 10.1093/ajh/3.8.635
46. Yasujima M, Abe K, Tanno M, et al. Effects of digoxin on blood pressure responses to norepinephrine, angiotensin II and vasopressin in conscious rats. Tohoku J Exp Med. 1990; 162: 203-212. doi: 10.1620/tjem.162.203
47. Yasujima M, Abe K, Kanazawa M, et al. Calcium channel blockers reverse the sustained elevation of blood pressure induced by chronic infusion of endothelin in consciuos rats. Tohoku J Exp Med. 1990; 160: 157-165. doi: 10.1620/tjem.160.157
48. Yasujima M, Abe K, Kanazawa M, et al. Atrial natriuretic polypeptide and blood pressure regulation in rats with reduced renal mass. In: Atrial and Brain Natriuretic Peptides. In: Imura H, Matuo H, eds. Kodansha scientific Ltd, Tokyo. 1990; 391-399.
49. Kohzuki M, Johnston CI, Chai SY, Casley DJ, Mendelsohn FAO. In vitro autoradiographic endothelin S6B binding sites in rat tissues. Clin Exp Pharmacol Physiol. 1991; 18: 509-515.
50. Kohzuki M, Chai SY, Jackson B, et al. Angiotensin converting enzyme induction and inhibition in tissues: A new approach using quantitative in vitro autoradiography. J Hypertens. 1991; 9: 579-589.
51. Yasujima M, Abe K, Kanazawa M, et al. Antihypertensive effect of captopril and enalapril in endothelin-infused rats. Tohoku J Exp Med. 1991; 163: 219-227. doi: 10.1620/tjem.163.219
52. Yoshida K, Yasujima M, Kohzuki M, et al. Chronic synergistic effect of endothelin-1 and angiotensin II on blood pressure in conscious rats. J Cardiovasc Pharmacol. 1991; 17(Suppl 7): 514-516.
53. Kohzuki M, Chai SY, Paxinos G, Karavas A, Casley D, Johnston CI. Localization and characterization of endothelin receptor binding sites in rat brain visualized by in vitro autoradiography. Neuroscience. 1991; 42: 250-260. doi: 10.1016/0306-4522(91)90162-H
54. Kohzuki M, Chen BZ, Mooser V, Jandeleit K, Johnston CI. Angiotensin converting enzyme in the spontaneously hypertensive rat. Genetic Hypertension. 1992; 218: 503-505.
55. Kohzuki M, Yasujima M, Yoshida K, Kanazawa M, Yoshinaga K, Abe K. The kidney protecting effect of trandolapril in normotensive and hypertensive rats. Pharmacometrics. 1992; 44: 309-315.
56. Yoshida K, Yasujima M, Kohzuki M, Kanazawa M, Abe K, Yoshinaga K. Endothelin-1 augments presser response to angiotensin II infusion infusion in rats. Hypertension. 1992; 20: 292-297. doi: 10.1161/01.HYP.20.3.292
57. Yasujima M, Kanazawa M, Yoshida K, et al. Chronic treatment with anti-endothelin antibodies fails to modify the development of hypertension in stroke-prone spontaneously hypertensive rats. Tohoku J Exp Med. 1993; 169: 43-50. doi: 10.1620/tjem.169.43
58. Yasujima M, Yoshida K, Kanazawa M, et al. Urinary active kallikrein excretion and diabetic renal impairments in streptozotocin-treated rats. Tohoku J Exp Med. 1993; 171: 135-144. doi: 10.1620/tjem.171.135
59. Yasujima M, Kanazawa M, Yoshida K, et al. The augmented blood pressure response to chronic angiotensin II infusion in partially nephrectomized rats. Tohoku J Exp Med. 1993; 169: 271-277. doi: 10.1620/tjem.169.271
60. Kohzuki M, Yasujima M, Kanazawa M, et al. Angiotensin converting enzyme inhibitors and progression of chronic renal mass. Inhibition of the Renin-Angiotensin System; Recent Advances. In: Sever P, MacGregor G, eds. Gardiner-Caldwell communications Ltd, Hong-Kong. 1994; 63-68.
61. Kohzuki M, Yasujima M, Yoshida K, Kanazawa M, Abe K. Antihypertensive and antiproteinuretic effects of losartan in spontaneously hypertensive rats with chronic renal failure. Hypertens Res. 1994; 17: 173-178.
62. Kohzuki M. The role of renin-angiotensin system on myocardial hypertrophy in rats with chronic myocardial infarction. Annual Report of the Cardiovascular Research Foundation. 1994; 4: 38-41.
63. Yoshida K, Yasujima M, Kohzuki M, Kanazawa M, Abe K. The effects of chronic treatment of calcium channel blockers and angiotensin converting enzyme inhibitors on renal function in the streptozotocin diabetic rats. Hypertens Res. 1994; 17: 35-41.
64. Kohzuki M, Yasujima M, Kanazawa M, et al. Antihypertensive and renal-protective effects of losartan in streptozotocin diabetic rats. J Hypertens. 1995; 13: 97-103.
65. Kohzuki M, Yasujima M, Kanazawa M, Yoshida K, Abe K. Do kinins mediate cardioprotective and renoprotective effects of cilazapril in spontaneously hypertensive rats (SHRs) with renal ablation ? Clin Exp Pharmacol Physiol. 1995; 22(Suppl 1): 357-359.
66. Kohzuki M, Yasujima M, Liu PF, et al. Cardiovascular and renal protective effects of losartan in spontaneously hypertensive rats with diabetes mellitus. Clin Exp Pharmacol Physiol. 1995; 22 (Suppl 1): 366-367.
67. Kohzuki M, Yasujima M, Kanazawa M, Yoshida K, Sato T, Abe K. Effects of recombinant human erythropoietin (EPO) on blood pressure and renal function in SHRs with chronic renal failure. Clin Exp Pharmacol Physiol. 1995; 22 (Suppl 1): 165-166.
68. Kohzuki M, Kanazawa M, Liu PF, et al. Kinin and angiotensin II receptor antagonists in rats with chronic renal failure: the chronic effects on cardio- and reno-protection of angiotensin converting enzyme inhibitors. J Hypertens. 1995; 13: 1785-1790.
69. Kohzuki M, Onodera H, Yasujima M, et al. Endothelin receptors in ischemic rat brain and Alzheimer brain. J Cardiovasc Pharmacol. 1995; 26(Suppl 3): 329-331.
70. Yoshida K, Kohzuki M, Yasujima M, Kanazawa M, Abe K. Effects of benidipine, a calcium antagonist, on urinary kallikrein excretion and renal impairment in experimental diabetes. J Hypertens. 1996; 14: 215-222.
71. Kohzuki M, Kanazawa M, Yoshida K, et al. Cardiac angiotensin converting enzyme and endothelin receptor in rats with chronic myocardial infarction. J pn Circ J. 1996; 60: 972-980. doi: 10.1253/jcj.60.972
72. Jiang Z-L, Harada T, Kohzuki M, Kamimoto M, Sato T. Serum enzymatic changes in insulin-induced hypoglycaemia in experimental rabbits. Tohoku J Exp Med. 1996; 179: 219-222.
73. Kohzuki M, Kanazawa M, Yoshida K, et al. Cardiomegaly and vasoactive hormones in rats with chronic myocardial infarction: long-term effects of chlorothiazide. Clin Sci. 1996; 90: 31-36.
74. Kohzuki M, Yoshida K, Kamimoto M, Wu X-M, Hashimoto M, Sato T. Disability prevention of chronic heart failure (CHF): Introduction of an animal heart failure model to the study of rehabilitation medicine. In: Ueda S, Nakamura R, Ishigami S, eds. Proceedings of the 8th World Congress of the International Rehabilitation Medicine Association (IRMA VIII). 1997; 1001-1004.
75. Kohzuki M, Kamimoto M, Wu X-M, et al. Disability prevention of chronic renal failure (CRF): Introduction of an animal renal failure model to the study of rehabilitation medicine. In: Ueda S, Nakamura R, Ishigami S, eds. Proceedings of the 8th World Congress of the International Rehabilitation Medicine Association (IRMA VIII). 1997; 1033-1036.
76. Keitoku M, Kohzuki M, Kato H, et al. FMLP actions and its binding sites in isolated human coronary arteries. J Mol Cell Cardiol. 1997; 29: 881-894. doi: 10.1006/jmcc.1996.0291
77. Kohzuki M, Kamimoto M, Wu X-M, Yoshida K, Watanabe M, Sato T. Disability prevention of chronic renal failure (CRF): Effects of mild to moderate exercise in rats with CRF. In: Ueda S, Nakamura R, Ishigami S, eds. Proceedings of the 8th World Congress of the International Rehabilitation Medicine Association (IRMA VIII). 1997; 1037-1040.
78. Yoshida K, Kohzuki M, Casley DJ, Johnston CI. Angiotensin-converting enzyme inhibition and salt in experimental myocardial infarction. J Cardiovasc Pharmacol. 1998; 32: 357-365.
79. Kohzuki M, Kamimoto M, Wu X-M, Yoshida K, Sato T. Chronic effects of FR139317 and enalapril on renal failure rats with moderate exercise. J Cardiovasc Pharmacol. 1998; 31(Suppl 1): 486-488.
80. Kohzuki M, Tanda S, Hori K, et al. Endothelin receptors and angiotensin II receptors in tumor tissue. J Cardiovasc Pharmacol. 1998; 31(Suppl 1): 531-533.
81. Jiang Z-L, Harada T, Yokokawa M, Kohzuki M, Sato T. Muscle damage induced by experimental hypoglycemia. Metabolism. 1998; 47: 1472-1476.
82. Kuge N, Kohzuki M, Sato T. Relation between natriuresis and urinary excretion of hydrogen peroxide. Free Rad Res. 1999; 30: 119-123.
83. Kohzuki M, Wu X-M, Kamimoto M, et al. Renal-protective effect of non-depressor dose of cicletanine in streptozotocin diabetic rats. J Hypertens. 1999; 17: 695-700.
84. Yoshida T, Kohzuki M, Yoshida K, et al. Physical and Psychological Improvements after Phase II Cardiac Rehabilitation in Patients with Myocardial Infarction. Nursing and Health Sciences. 1999; 1: 163-170. doi: 10.1046/j.1442-2018.1999.00021.x
85. Kohzuki M, Tanda S, Hori K, Suzuki M, Yoshida K, Sato T. Decreased binding sites of angiotensin II in rat LY-80 and AH109A tumor and human gastric cancer using quantitative in vitro autoradiography. International Angiology. 2000; 19: 52-58.
86. Kohzuki M, Wu X-M, Kamimoto M, et al. Renal-protective effect of non-depressor dose of cicletanine in diabetic spontaneously hypertensive rats. Am J Hypertens. 2000; 13: 298-306. doi: 10.1016/S0895-7061(99)00189-2
87. Yoshida K, Arakawa M, Ishida S, Kohzuki M, Sato T, Sasaki Y. A case of lobenzarit disodium-induced hyperkalemia successfully treated with fludrocortisone acetate. Clin Exp Nephrol. 2000; 4: 67-70.
88. Kohzuki M, Abo T, Watanabe M, et al. Rehabilitating patients with hepatopulmonary syndrome using living-related orthotopic liver transplant: A case report. Archives Physical Med & Rebabilitation. 2000; 81: 1527-1530. doi: 10.1053/apmr.2000.9393
89. Yoshida T, Yoshida K, Yamamoto C, et al. Effects of two-week hospitalized phase II cardiac rehabilitation program on physical capacity, lipid profiles and psychological variables in patients with myocardial infarction. Jpn Circ J. 2001; 65: 87-93. doi:10.1253/jcj.65.87
90. Yoshida K, Kohzuki M, Wu X-M, Xu X-L, Sato T. Renoprotective effects of troglitazone in spontaneously hypertensive rats with chronic renal failure. J Hypertens. 2001; 19: 503-510.
91. Watanabe M, Kohzuki M, Meguro K, Goto Y, Sato T. Marked Improvement of Neuropsychological Impairment in a Patient with Chronic Obstructive Pulmonary Disease after Lung Volume Reduction Surgery. Tohoku Journal of Experiment Medicine. 2001; 193: 67-72. doi:10.1620/tjem.193.67
92. Takahashi C, Kagaya Y, Namiuchi S, et al. Non selective ET receptor antagonist initiated soon after the onset of myocardial infarction may deteriorate 24-hour survival. J Cardiovasc Pharmacol. 2001; 38: 29-38.
93. Goto Y, Kohzuki M, Watanabe M, Mori N, Kurosawa H. Improved activities of daily living (ADL) and quatity of life (QOL) following lung volume reduction surgery (LVRS) for emphysema. Proceedings of the 1st World Congress of the International Society of Physical and Rehabilitation Medicine, Monduzzi Editore, Bologna. 2001; 837-840.
94. Kohzuki M, Yokogawa M, Goto Y, et al. Heart disease and hyperinsulinemia in Japanese stroke patients. Proceedings of the 1st World Congress of the International Society of Physical and Rehabilitation Medicine, Monduzzi Editore, Bologna. 2001; 531-535.
95. Saiki S, Sato T, Kohzuki M, Kamimoto M, Yoshida T. Changes in serum hypoxanthine levels by exercise in obese subjects. Metabolism. 2001; 50: 627-630. doi: 10.1053/meta.2001.24197
96. Kohzuki M, Kamimoto M, Wu X-M, et al. Renal-protective effects of chronic exercise and antihypertensive therapy in hypertensive rats with renal failure. J Hypertens. 2001; 19: 1877-1882.
97. Kanazawa M, Kohzuki M, Yoshida K, et al. Combination therapy with an angiotensin-converting enzyme(ACE)inhibitor and a calcium antagonist: beyond the renoprotective effects of ACE inhibitor monotherapy in a spontaneous hypertensive rat with renal ablation. Hypertens Res. 2002; 25: 447-453. doi: 10.1291/hypres.25.447
98. Chida K, Tanaka T, Saito H, et al. Ventriculography using ECG-gated multiple diastolic injection of contrast material in pediatric angiocardiography. Pediatr Cardiol. 2002; 23: 200-204. doi: 10.1007/s00246-001-0047-6
99. Minami N, Mori N, Nagasaka M, Kurosawa H, Kanazawa M, Kohzuki M. Effect of estrogen on pressor responses to α1-Adrenoreceptor agonist in conscious female rats. Hypertens Res. 2002; 25: 609-613.
100. Kawamura T, Yoshida K, Sugawara A, et al. Impact of exercise and ACE inhibition on TNF-α and leptin in hypertensive rats. Hypertens Res. 2002; 25: 919-926. doi: 10.1291/hypres.25.919
101. Yoshida K, Xu X-L, Kawamura T, Ji L, Kohzuki M. Chronic angiotensin-converting enzyme inhibition and angiotensin II antagonism in rats with chronic renal failure. J Cardiovasc Pharmacol. 2002; 40: 533-542.
102. Chida K, Saito H, Takai Y, et al. Stability of electron-beam energy monitor for quality assurance of the electron-beam energy from radiotherapy accelerators. Tohoku J Exp Med. 2002; 198: 197-201. doi: 10.1620/tjem.198.197
103. Kawamura T, Yoshida K, Sugawara A, et al. Regulation of skeletal muscle peroxisome proliferator-activated receptor γ expression by angiotensin-converting enzyme inhibition in fructose-fed hypertensive rats. Hypertens Res. 2003; 25: 919-926.
104. Ishizuka T, Ito O, Tan L, et al. Regulatoin of P-450 4A activity by peroxisome proliferator-activated receptors in the rat kidney. Hypertens Res. 2003; 26: 929-936. doi: 10.1291/hypres.26.929
105. Kanazawa M, Li L, Matsumoto K, et al. Disability prevention of chronic renal failure (CRF): effects of moderate to intense exercise in rats with CRF. Proceedings of the 2nd World Congress of the International Society of Physical and Rehabilitation Medicine, Monduzzi Editore, Bologna. 2003; 517-520.
106. Minami N, Yoshikawa T, Kataoka H, et al. Effects of exercise and β-blocker on blood pressure and baroreflexes in spontaneously yypertensive rats. Am J Hypertens. 2003; 16: 966-972. doi: 10.1016/S0895-7061(03)01010-0
107. Yoshida K, Kawamura T, XU HL, Ji L, Mori N, Kohzuki M. Effects of exercise training on glomerular structure in fructose-fed spontaneously hypertensive rats. Hypertens Res. 2003; 26: 907-914. doi: http://dx.doi.org/10.1291/hypres.26.907
108. Kohzuki M, Wu X-M, Sato T, et al. Disability prevention of renal failure: effects of exercise and enalapril in Thy-1 nephritis rats. Proceedings of the 2nd World Congress of the International Society of Physical and Rehabilitation Medicine, Monduzzi Editore, Bologna. 2003; 521-524.
109. Ji L, Kohzuki M, Yoshida K, et al. Disability prevention of renal failure: effects of exercise of exercise and enalapril in nephrotic rats. Proceedings of the 2nd World Congress of the International Society of Physical and Rehabilitation Medicine, Monduzzi Editore, Bologna. 2003; 525-528.
110. Sasaki Y, Mue S, Kasai Y, et al. Gender and age differences in cardiovascular responses to 5 minutes walking exercise. Proceedings of the 2nd World Congress of the International Society of Physical and Rehabilitation Medicine, Monduzzi Editore, Bologna. 2003; 481-484.
111. Kataoka H, Kumagai E, Takahashi M, et al. Generic & disease-specific quality of life, anxiety and depression in Japanese. Proceedings of the 2nd World Congress of the International Society of Physical and Rehabilitation Medicine, Monduzzi Editore, Bologna. 2003; 643-646.
112. Mori N, Kurosawa H, Ito A, et al. Altered ventilatory patterns and efficiency in patients with severe cerebral palsy with spinal rotation, scoliosis, and mental retardation. Proceedings of the 2nd World Congress of the International Society of Physical and Rehabilitation Medicine, Monduzzi Editore, Bologna. 2003; 461-464.
113. Matsumoto K, Kurosawa H, Goto Y, et al. Reduced lung volume after chest physiotherapy. Proceedings of the 2nd World Congress of the International Society of Physical and Rehabilitation Medicine, Monduzzi Editore, Bologna. 2003; 485-488.
114. Kawamura T, Kanazawa M, Li L, et al. Peripheral adaptation to 12-week exercise training in rats with renal failure. Proceedings of the 2nd World Congress of the International Society of Physical and Rehabilitation Medicine, Monduzzi Editore, Bologna. 2003; 529-531.
115. Nagasaka M, Kohzuki M, Fujii T, et al. Low-voltage electrical stimulation induced angiogenic growth factors in hindlimb ischemia model of rats. Proceedings of the 2nd World Congress of the International Society of Physical and Rehabilitation Medicine, Monduzzi Editore, Bologna. 2003; 767-771.
116. Goto Y, Kurosawa H, Mori N, Matsumoto K, Kohzuki M. Long-term effects of lung volume reduction in exercise capacity, activities of daily living (ADL) and quality of life. Proceedings of the 2nd World Congress of the International Society of Physical and Rehabilitation Medicine, Monduzzi Editore, Bologna. 2003; 493-495.
117. Kurosawa H, Kohzuki M. Visualization of airflow limitation in emphysematous lung. N Eng J Med. 2004; 350: 1036.
118. Minami N, Mori N, Nagasaka M, et al. Effect of high-salt diet or chronic captopril treatment on exercise capacity in normotensive rats. Clin Exp Pharmacol Physiol. 2004; 31: 197-201. doi: 10.1111/j.1440-1681.2004.03980.x
119. Chida K, Saito H, Nagasaka T, Otani H, Kohzuki M, Zuguchi M. Rapid-sequence phosphorus-31 magnetic resonance spectroscopy of the human heart using a 1.5t-clinical system. Acta Radiol. 2004; 45: 30-37. doi: 10.1080/02841850410003284
120. Kanazawa M, Kohzuki M, Yoshida K, et al. Enhanced renoprotective effect of an angiotensin-converting enzyme(ACE)inhibitor combined with αadrenergic antagonist in a spontaneous hypertensive rat with renal ablation. Hypertens Res. 2004; 27: 509-515.
121. Goto Y, Kurosawa H, Mori N, et al. Improved activities of daily living, psychological state, and health-related quality of life following lung volume reduction surgery for 12 months in patients with severe emphysema. Respirology. 2004; 9: 1-9.
122. Chida K, Saito H, Zuguchi M, et al. Does digital acquisition reduce patients skin dose in cardiac interventional procedures? An experimental study. Am J Roentogenol. 2004; 183: 1111-1114.
123. Han CW, Lee EJ, Iwaya T, Kataoka H, Kohzuki M. Development of the Korean version of Short-Form 36-Item Health Survey: health related QOL of healthy elderly peple and elderly patients in Korea. Tohoku J Exp Med. 2004; 203: 189-194. doi: http://dx.doi.org/10.1620/tjem.203.189
124. Han CW, Yajima Y, Lee EJ, Park CM, Nakajima K, Kohzuki M. Development and construct validation of the Korean competence scale. Tohoku J Exp Med. 2004; 203: 331-337. doi: http://dx.doi.org/10.1620/tjem.203.331
125. Goto Y, Kurosawa H, Mori N, Kurokawa Y, Hida W, Kohzuki M. Improved activities of daily living psychological state and health-related quality of life for 12 months following lung volume reduction surgery in patients with severe emphysema. Respirology. 2004; 9: 337-344. doi: 10.1111/j.1440-1843.2004.00591.x
126. Kawamura T, Yoshida K, Sugawara A, et al. Regulation of skeletal muscle peroxisome proliferator-activated receptor γ expression by exercise and angiotensin-converting enzyme inhibition in fructose-fed hypertensive rats. Hypertens Res. 2004; 27: 61-70. doi: http://dx.doi.org/10.1291/hypres.27.61
127. Yoshida K, Kohzuki M. Clinical and experimental aspects of olmesartan medoxomil, a new angiotensin II receptor antagonist. Cardiovasc Drug Rev. 2004; 22: 285-308.
128. Sarkis A, Ito O, Mori T, et al. Cytochrome P-450 dependent metabolism of arachidonic acid in the kidney of rats with diabetes insipidus. Am J Physiol Renal Physiol. 2005; 289: F1333-F1340. doi: 10.1152/ajprenal.00188.2005
129. Chida K, Otani H, Nagasaka T, et al. Feasibility of rapid-sequence 31P magnetic resonance spectroscopy in cardiac patients. Acta Radiol. 2005; 46: 386-390. doi: 10.1080/02841850510021283
130. Chida K, Zuguchi M, Sai M, et al. Optimization of tube potential-filter combinations for film-screen mammography a contrast detail phantom study. J Clin Imaging. 2005; 29: 246-250. doi: http://dx.doi.org/10.1016/j.clinimag.2004.11.003
131. Han CW, Yajima Y, Lee EJ, Nakajima K, Meguro M, Kohzuki M. Validity and utility of the craig hospital inventory of environmental factors for Korean Community-dwelling elderly with or without stroke. Tohoku J Exp. Med. 2005; 206: 41-49. doi: http://dx.doi.org/10.1620/tjem.206.41
132. Kanazawa M, Kohzuki M, Li L, et al. Disability prevention of chronic renal failure (CRF): enhanced effects of chronic exercise combined with angiotensin converting enzyme (ACE) inhibitor in rats with CRF. Proceedings of the 3rd World Congress of the International Society of Physical and Rehabilitation Medicine, Monduzzi Editore, Bologna. 2005; 697-700.
133. Kanazawa M, Kohzuki M, Kururi N, et al. The present details of cardiac rehabilitation and life style modification after acute myocardial infarction in Miyagi Prefecture, Japan. Proceedings of the 3rd World Congress of the International Society of Physical and Rehabilitation Medicine, Monduzzi Editore, Bologna. 2005; 593-595.
134. Ito O, Tan L, Sasaki Y, et al. Disability prevention of chronic renal failure (CRF): Effects of chronic exercise on cytochrome p-450 metabolism of arachidonic acid in rats. Proceedings of the 3rd World Congress of the International Society of Physical and Rehabilitation Medicine, Monduzzi Editore, Bologna. 2005; 701-704.
135. Nagasaka M, Kohzuki M, Dobsak P, Imachi H, Minami N. New strategy of physical therapy effect of low and high voltage electrical stimulation on angiogenesis in rat skeletal muscle. Proceedings of the 3rd World Congress of the International Society of Physical and Rehabilitation Medicine, Monduzzi Editore, Bologna. 2005; 845-848.
136. Nagasaka M, Kohzuki M, Dobsak P, Imachi H, Minami N. New strategy of physical therapy effect of short-term electrical stimulation on angiogenesis in rat skeletal muscle. Proceedings of the 3rd World Congress of the International Society of Physical and Rehabilitation Medicine, Monduzzi Editore, Bologna. 2005; 849-852.
137. Ogawa M, Kondo T, Shindo K, et al. Rehabilitation for incomplete paraplegia with severe complications following aortic replacement. Proceedings of the 3rd World Congress of the International Society of Physical and Rehabilitation Medicine, Monduzzi Editore, Bologna. 2005; 153-156.
138. Sasaki Y, Kanazawa M, Tufescu A, Ito O, Kohzuki M. Disability prevention of chronic renal failure (CRF): Effect of combination therapy with low protein diet, chronic exercise and angiotensin II receptor antagonist in rat with CRF. Proceedings of the 3rd World Congress of the International Society of Physical and Rehabilitation Medicine, Monduzzi Editore, Bologna. 2005; 711-714.
139. Tufescu A, Kohzuki M, Sasaki Y, et al. Disability prevention of chronic renal failure (CRF): Enhanced effects of chronic exercise combined with angiotensin II receptor antagonist in spontaneously type 2 diabetes mellitus rats with CRF. Proceedings of the 3rd World Congress of the International Society of Physical and Rehabilitation Medicine, Monduzzi Editore, Bologna. 2005; 693-696.
140. Harada T, Watanabe H, Mori N, et al. The effects of rehabilitation on lipid metabolism of stroke patients. Proceedings of the 3rd World Congress of the International Society of Physical and Rehabilitation Medicine, Monduzzi Editore, Bologna. 2005; 95-98.
141. Kohzuki M. Cardiac rehabilitation in Japan: prevalence, safety and future plans. J HK Coll Cardiol. 2006; 14: 43-45.
142. Kanazawa M, Kawamura T, Li L, et al. Combination of exercise and enalapril enhances renoprotective and peripheral effects in rats with renal ablation. Am J Hypertens. 2006; 19: 80-86. doi: 10.1016/j.amjhyper.2005.07.009
143. Minami N, Mori N, Nagasaka M, et al. Mechanism behind augmentation in baroreflex sensitivity after acute exercise in spontaneously hypertensive rats. Hypertens Res. 2006; 29: 117-122. doi: 10.1291/hypres.29.117
144. Dobsák P, Nováková M, Fiser B, et al. Electrical stimulation of skeletal muscles. An alternative to aerobic exercise training in patients with chronic heart failure? Int Heart J. 2006; 47: 441-453. doi: http://dx.doi.org/10.1536/ihj.47.441
145. Ito O, Nakamura Y, Tan L, et al. Expression of cytochrome P-450 4 enzymes in the kidney and liver: regulation by PPAR and species-difference between rat and human. Mol Cell Biochem. 2006; 284: 141-148. doi: 10.1007/s11010-005-9038-x
146. Nagasaka M, Kohzuki M, Fujii T, et al. effect of low-voltage electrical stimulation on angiogenic growth factors in ischaemic rat skeletal muscle. Clin Exp Pharmacol Physiol. 2006; 33: 623-627. doi: 10.1111/j.1440-1681.2006.04417.x
147. Dobsák P, Nováková M, Siegelová J, et al. Low-frequency electrical stimulation increases muscle strength and improves blood supply in patients with chronic heart failure. Circ J. 2006; 70: 75-82. doi: http://dx.doi.org/10.1253/circj.70.75
148. Chida K, Saito H, Otani H, et al. Relationship between fluoroscopic time, dose-area product, body weight, and maximum radiation skin dose in cardiac interventional procedures. AJR Am J Roentgenol. 2006; 186: 774-778.
149. Chida K, Otani H, Kohzuki M, et al. The relationship between plasma BNP level and the myocardial phosphocreatine/adenosine triphosphate ratio determined by phosphorus-31 magnetic resonance spectroscopy in patients with dilated cardiomyopathy. Cardiology. 2006; 106: 132-136. doi: 10.1159/000092767
150. Chida K, Saito H, Kagaya Y, et al. Indicators of the maximum radiation dose to the skin during percutaneous coronary intervention in different target vessels. Catheter Cardiovasc Interv. 2006; 68: 236-241. doi: 10.1002/ccd.20830
151. Han CW, Yajima Y, Nakajima K, Lee EJ, Meguro M, Kohzuki M. Construct validity of the Frenchay Activities Index for community-dwelling elderly in Japan. Tohoku J Exp Med. 2006; 210: 99-107. doi: http://dx.doi.org/10.1620/tjem.210.99
152. Goto Y, Saito M, Iwasaka T, et al. Poor implementation of cardiac rehabilitation despite broad dissemination of coronary interventions for acute myocardial infarction in Japan: a nationwide survey. Circ J. 2007; 71: 173-179. doi:http://dx.doi.org/10.1253/circj.71.173
153. Tajima M, Kohzuki M, Azuma S, Saeki S, Meguro M, Sugawara J. Difference in quality of life according to the severity of malocclusion in Japanese orthodontic patients. Tohoku J Exp Med. 2007; 212: 71-80.
154. Azuma S, Kohzuki M, Saeki S, Tajima M, Igarashi K, Sugawara J. Beneficial Effects of Orthodontic Treatment on Quality of Life in Patients with Malocclusion. Tohoku J Exp Med. 2008; 213.
155. Minami N, Mori N, Nagasaka M, et al. Exercise training fails to modify arterial baroreflex sensitivity in ovariectomized female rats. Tohoku J Exp Med. 2007; 211: 339-345. doi: http://dx.doi.org/10.1620/tjem.211.339
156. Minami N, Li Y, Guo Q, et al. Effects of angiotensin-converting enzyme inhibitor and exercise training on exercise capacity and skeletal muscle. J Hypertens. 2007; 25: 1241-1248.
157. Park HJ, Kim S, Yong JS, et al. Reliability and validity of the Korean version of Kidney Disease Quality of Life instrument (KDQOL-SF). Tohoku J Exp Med. 2007; 211: 321-329. doi: http://dx.doi.org/10.1620/tjem.211.321
158. Goto Y, Kohzuki M, Meguro M, Kurosawa H. Long-term beneficial effects of lung volume reduction surgery on quality of life in patients with chronic obstructive pulmonary disease. Tohoku J Exp Med. 2007; 213: 157-166. doi:http://dx.doi.org/10.1620/tjem.213.157
159. Jiang Z, Kohzuki M, Harada T, Sato T. Glutathione suppresses increase of serum creatine kinase in experimental hypoglycemia. Diabetes Res Clin Pract. 2007; 77: 357-362. doi: http://dx.doi.org/10.1016/j.diabres.2007.01.014
160. Chida K, Fuda K, Saito H, et al. Patient skin dose in cardiac interventional procedures: conventional fluoroscopy versus pulsed fluoroscopy. Catheter Cardiovasc Interv. 2007; 69: 115-121. doi: 10.1002/ccd.20961
161. Chida K, Kagaya Y, Saito H, et al. Total entrance skin dose: an effective indicator of maximum radiation dose to the skin during percutaneous coronary intervention. Am J Roentgenol. 2007; 189: W224-W227.
162. Chida K, Fuda K, Kagaya Y, et al. Influence of the target vessel on the location and area of maximum skin dose during percutaneous coronary intervention. Acta Radiol. 2007; 48: 846-850. doi: 10.1080/02841850701468875
163. Maeda M, Kohzuki M, Tanaka N, Nagata M, Maniwa S, Watanabe I. Clinico-physchological worker for rehabilitation service in Japan. Proceedings of the 4th World Congress of the International Society of Physical and Rehabilitation Medicine, Monduzzi Editore, Bologna. 2007.
164. Kanazawa M, Kawamura T, Li L, et al. Disability prevention of chronic renal failure (CRF): Enhanced renoprotective and peripheral effects of chronic exercise combined with angiotensin converting enzyme inhibitor in rats with CRF. Proceedings of the 4th World Congress of the International Society of Physical and Rehabilitation Medicine, Monduzzi Editore, Bologna. 2007; 699-702.
165. Nagasaka M, Dobsak P, Mori N, et al. The effect of electrical stimulation on skeletal muscle in patients with chronic obstructive pulmonary disease (COPD). Proceedings of the 4th World Congress of the International Society of Physical and Rehabilitation Medicine, Monduzzi Editore, Bologna. 2007; 647-649.
166. Nagasaka M, Dobsak P, Mori N, et al. The influence of electrical stimulation on skeletal muscle in patients with left ventricular assist device (LVAD). Proceedings of the 4th World Congress of the International Society of Physical and Rehabilitation Medicine, Monduzzi Editore, Bologna. 2007; 651-654.
167. Imanishi R, Kanazawa M, Ishida A, et al. The prognosis after a two-week, hospitalized recovery phase cardiac rehabilitation program in patients with acute myocardial infarction. Proceedings of the 4th World Congress of the International Society of Physical and Rehabilitation Medicine, Monduzzi Editore, Bologna. 2007; 613-616.
168. Ito D, Ito O, Cao P, Kanazawa M, Kohzuki M. Disability prevention of cardiovascular and chronic kidney diseases: Effect of exercise training on blood pressure and the expression of nitric oxide synthase in spontaneously hypertensive rats. Proceedings of the 4th World Congress of the International Society of Physical and Rehabilitation Medicine Monduzzi Editore, Bologna. 2007; 621-623.
169. Tufescu A, Kanazawa M, Ishida A, Lu H, Sasaki Y, Kohzuki M. Effects of combination therapy with chronic exercise (EX) and losartan (LOS) in spontaneously diabetes mellitus rats with nephropathy. Proceedings of the 4th world congress of the international society of physical and rehabilitation medicine, Monduzzi Editore, Bologna. 2007; 703-706.
170. Lu H, Kanazawa M, Ishida A, Tufescu A, Sasaki Y, Kohzuki M. Disability prevention of chronic renal failure (CRF): Combination of chronic exercise and antihypertensive therapy enhances renoprotective effects in rats with CRF. Proceedings of the 4th world congress of the international society of physical and rehabilitation medicine, Monduzzi Editore, Bologna. 2007; 695-698.
171. Tan L, Ito O, Niu K, et al. Disability prevention of metabolic syndrome: Effects of a combination therapy of exercise training and atorvastatin on plasma glucose and adipocytokine in Zucker fatty rats. Proceedings of the 4th World Congress of the International Society of Physical and Rehabilitation Medicine, Monduzzi Editore, Bologna. 2007; 625-627.
172. Svacinová H, Nováková M, Placheta Z, et al. Benefit of combined cardiac rehabilitation on exercise capacity and cardiovascular parameters in patients with type 2 diabetes. Tohoku J Exp Med. 2008; 215:103-111.
173. Guo Q, Minami N, Mori N, et al. Effects of antihypertensive drugs and exercise training on insulin sensitivity in spontaneously hypertensive rats. Hypertens Res. 2008; 31: 525-533. doi: 10.1291/hypres.31.525
174. Nakayama T, Hirose T, Totsune K, et al. Increased gene expression of urotensin II-related peptide in the hearts of rats with congestive heart failure. Peptides. 2008; 29: 801-808. doi: 10.1016/j.peptides.2007.12.018
175. Azuma S, Kohzuki M, Saeki S, Tajima M, Igarashi K, Sugawara J. Beneficial effects of orthodontic treatment on quality of life in patients with malocclusion. Tohoku J Exp Med. 2008; 214: 39-50. doi: http://dx.doi.org/10.1620/tjem.214.39
176. Tufescu A, Kanazawa M, Ishida A, et al. Combination of exercise and losartan enhances renoprotective and peripheral effects in spontaneously type 2 diabetes mellitus rats with nephropathy. J Hypertens. 2008; 26: 312-321. doi:10.1097/HJH.0b013e3282f2450b
177. Mori N, Hirose T, Nakayama T, et al. Increased expression of urotensin II-related peptide and its receptor in kidney with hypertension or renal failure. Peptides. 2008. doi: 10.1016/j.peptides.2008.09.021
178. Hirose T, Totsune K, Mori N, et al. Increased expression of adrenomedullin 2/intermedin in rat hearts with congestive heart failure. Eur J Heart Fail. 2008; 10: 840-849. doi: 10.1016/j.ejheart.2008.06.020
179. Chida K, Nagasaka T, Kohzuki M, et al. Feasibility of cardiac MR examination during quantitative isometric muscular exercise. Acta Cardiol. 2008; 63: 547-552.
180. Kohzuki M, Kawamura T, Ishida A. Outpatient phase III cardiac rehabilitation (CR) and the training system of the masters of CR in Japan. J HK Coll Cardiol. 2008; 16(Suppl 1): A23-A28.
181. Kohzuki M, Nagasaka M, Dobsak P. Electrical stimulation of skeletal muscles in patients with heart failure: an alternative to aerobic training? J HK Coll Cardiol. 2008; 16(Suppl 1): A38-A42.
182. Dobsak P, Al-Gergawi S, Sigelova J, et al. Low-frequency electromyostimulation improves autonomic nervous regulation in patients with end-stage chronic heart failure. Proceedings of the 5th World Congress of the International Society of Physical and Rehabilitation Medicine. 2009; 23-25.
183. Nagasaka M, Dobsak P, Mori N, et al. Electrical stimulation would be an alternative to exercise training in patients with COPD. Proceedings of the 5th World Congress of the International Society of Physical and Rehabilitation Medicine. 2009; 82-83.
184. Mori N, Hirose T, Nakayama T, et al. Increased expression of urotensin II-related peptide and its receptor in kidney with hypertension or renal failure. Peptides. 2009; 30: 400-408. doi: 10.1016/j.peptides.2008.09.021
185. Mori N, Ohtsuki K, Yamamoto J, et al. The minute ventilation to carbon dioxide production relationship in patients undergoing hematopoietic stem cell transplantation. Proceedings of the 5th World Congress of the International Society of Physical and Rehabilitation Medicine. 2009; 75-77.
186. Hirose T, Takahashi K, Mori N, et al. Increased expression of urotensin II, urotensin II-related peptide and urotensin II receptor mRNAs in the cardiovascular organs of hypertensive rats: comparison with endothelin-1. Peptides. 2009; 30: 1124-1129. doi: 10.1016/j.peptides.2009.02.009
187. Takahashi K, Hirose T, Mori N, et al. The renin-angiotensin system, adrenomedullins and urotensin II in the kidney: possible renoprotection via the kidney peptide systems. Peptides. 2009; 30: 1575-1585. doi: 10.1016/j.peptides.2009.05.018
188. Hirose T, Mori N, Totsune K, et al. Gene expression of (pro)renin receptor is upregulated in hearts and kidneys of rats with congestive heart failure. Peptides. 2009; 30: 2316-2322. doi: 10.1016/j.peptides.2009.09.015
189. Imanishi R, Nakagawa H, Matsumoto K, et al. Lower urinary tract dysfunction in elderly people staying at a residential facility. Proceedings of the 5th World Congress of the International Society of Physical and Rehabilitation Medicine. 2009; 48.
190. Freeman S, Ebihara S, Ebihara T, et al. Olfactory stimuli and enhanced postural stability in older adults. Gait Posture. 2009; 29: 658-660. doi: 10.1016/j.gaitpost.2009.02.005
191. Cao P, Ito O, Guo Q, et al. Disability prevention of cardiovascular and chronic kidney diseases: Effect of a combination therapy with exercise training and superoxide dismutase mimetic on blood pressure and nitric oxide synthase in spontaneously hypertensive rats. Proceedings of the 5th World Congress of the International Society of Physical and Rehabilitation Medicine. 2009; 13-14.
192. Suda C, Kanazawa M, Yao Q, et al. Disability prevention of chronic renal failure (CRF): Effects of combination therapy with chronic exercise and G-CSF in rats with CRF. Proceedings of the 5th World Congress of the International Society of Physical and Rehabilitation Medicine. 2009; 120-121.
193. Chang Y, Ito O, Cao P, et al. Disability prevention of metabolic syndrome: Effects of exercise training on steatosis and fatty acid metabolisms in the liver of Zucker fatty rats. Proceedings of the 5th World Congress of the International Society of Physical and Rehabilitation Medicine. 2009; 18-19.
194. Chida K, Morishima Y, Masuyama H, et al. Effect of radiation monitoring method and formula differences on estimated physician dose during percutaneous coronary intervention. Acta Radiol. 2009; 50: 170-173. doi: 10.1080/02841850802616745
195. Chida K, Inaba Y, Saito H, et al. Radiation dose of interventional radiology system using a flat-panel detector. Am J Roentgenol. 2009; 193: 1680-1685. doi: 10.2214/AJR.09.2747
196. Han CW, Lee EJ, Kohzuki M. Validity and reliability of the Frenchay Activities Index for community-dwelling elderly in South Korea. Tohoku J Exp Med. 2009; 217: 163-168. doi: http://dx.doi.org/10.1620/tjem.217.163
197. Lu H, Kanazawa M, Ishida A, et al. Combination of Chronic Exercise and Antihypertensive Therapy Enhances Renoprotective Effects in Rats with Renal Ablation. Am J Hypertens. 2009; 22: 1101-1106. doi: 10.1038/ajh.2009.148
198. Yamanda S, Ebihara S, Ebihara T, Yamasaki M, Arai H, Kohzuki M. Bacteriology of aspiration pneumonia due to delayed triggering of the swallowing reflex in elderly patients. Hosp Infect. 2010; 74: 399-401. doi: 10.1016/j.jhin.2009.08.011
199. Yamasaki M, Ebihara S, Ebihara T, Yamanda S, Arai H, Kohzuki M. Effects of capsiate on the triggering of the swallowing reflex in elderly patients with aspiration pneumonia. Geriatr Gerontol Int. 2010; 10: 107-109. doi:10.1111/j.1447-0594.2009.00566.x
200. Ebihara S, Kohzuki M. Taste disturbance by angiotensin-converting enzyme inhibitors/angiotensin-2 receptor blockers. Kidney Int. 2010; 77: 649. doi: 10.1038/ki.2009.528
201. Hirose T, Mori N, Totsune K, et al. Increased expression of (pro)renin receptor in the remnant kidneys of 5/6 nephrectomized rats. Regul Pept. 2010; 159: 93-99.
202. Hirose T, Totsune K, Mori N, et al. Expression of adrenomedullin 2/intermedin, a possible reno-protective peptide, is decreased in the kidneys of rats with hypertension or renal failure. Am J Physiol Renal Physiol. 2010; 299: F128-F134.
203. Freeman S, Kurosawa H, Ebihara S, Kohzuki M. Caregiving burden for the oldest old: a population based study of centenarian caregivers in Northern Japan. Arch Gerontol Geriatr. 2010; 50: 282-291. doi: 10.1016/j.archger.2009.04.008
204. Freeman S, Kurosawa H, Ebihara S, Kohzuki M. Understanding the oldest old in northern Japan: an overview of the functional ability and characteristics of centenarians. Geriatr Gerontol Int. 2010; 10: 78-84. doi: 10.1111/j.1447-0594.2009.00550.x
205. Kanezaki M, Ebihara S, Nikkuni E, et al. Perception of urge-to-cough and dyspnea in healthy smokers with decreased cough reflex sensitivity. Cough. 2010; 6: 1. doi: 10.1186/1745-9974-6-1
206. Chida K, Kato M, Saito H, et al. Optimizing patient radiation dose in intervention procedures. Acta Radiol. 2010; 51: 33-39. doi: 10.3109/02841850903229141
207. Guo Q, Minami N, Mori N, et al. Effects of estradiol, angiotensin-converting enzyme inhibitor and exercise training on exercise capacity and skeletal muscle in old female rats. Clin Exp Hypertens. 2010; 32: 1-8.
208. Ebihara S, Kohzuki M, Sumi Y, Ebihara T. Sensory stimulation to improve swallowing reflex and prevent aspiration pneumonia in elderly dysphagic people. J Pharmacol Sci. 2011; 115: 99-104.
209. Ebihara S, Ebihara T, Kanezaki M, et al. Aging deteriorated perception of urge-to-cough without changing cough reflex threshold to citric acid in female never-smokers. Cough. 2011; 7: 3. doi: 10.1186/1745-9974-7-3
210. Ebihara S, Ebihara T, Yamasaki M, Kohzuki M. Stimulating oral and nasal chemoreceptors for preventing aspiration pneumonia in the elderly. Yakugaku Zasshi. 2011; 131(12): 1677-1681. doi:http://dx.doi.org/10.1248/yakushi.131.1677
211. Ohishi J, Kurosawa H, Ogawa H, Irokawa T, Hida W, Kohzuki M. Application of impulse oscillometry for within-breath analysis in patients with chronic obstructive pulmonary disease: pilot study. BMJ Open. 2011; 1: e000184. doi:10.1136/bmjopen-2011-000184
212. Cao P, Ito O, Guo Q, et al. Endogenous hydrogen peroxide upregulates the expression of nitric oxide synthases in the kidney of spontaneously hypertensive rats. J Hypertens. 2011; 29: 1167-1174.
213. Sakata Y, Ito O, Watanabe H, Kohzuki M. The implementation of cardiac rehabilitation after acute myocardial infarction in Northern Japan. Proceedings of the 6th World Congress of the International Society of Physical and Rehabilitation Medicine. 2011; 38-39.
214. Rong R, Ito O, Mori N, Cao P, Kohzuki M. Exercise training decreases the enhanced expression of soluble (pro)renin receptor in the kidney of spontaneously hypertensive rats. Proceedings of the 6th World Congress of the International Society of Physical and Rehabilitation Medicine. 2011; 40-41.
215. Tamura Y, Mori N, Xu T, et al. Combined management program effects of chronic heart failure rehabilitation. Proceedings of the 6th World Congress of the International Society of Physical and Rehabilitation Medicine. 2011; 107-108.
216. Kim M, Ito O, Mori N, Nagasaka M, Ebihara S, Kohzuki M. The effect of exercise training on walking ability and health-related quality of life in patients with peripheral arterial disease. Proceedings of the 6th World Congress of the International Society of Physical and Rehabilitation Medicine. 2011; 36-37.
217. Sakuyama A, Ito O, Cao P, Ron R, Ito D, Kohzuki M. Effects of exercise training on the expression of angiotensin-converting enzyme in the kidney of spontaneously hypertensive rats. Proceedings of the 6th World Congress of the International Society of Physical and Rehabilitation Medicine. 2011; 143-144.
218. Kohzuki M, Sakata Y, Kawamura T, Ebihara S, Ito O. A paradigm shift in rehabilitation Medicine: From adding life to years to adding life to years and years to life. Asian Journal of Human Services. 2012; 2: 1-7.
219. Niu K, Asada M, Okazaki T, et al. Adiponectin pathway attenuates malignant mesothelioma cell growth. Am J Respir Cell Mol Biol. 2012; 46: 515-523. doi: 10.1165/rcmb.2011-0068OC
220. Liu M, Kohzuki M, Hamamura A, et al. How did rehabilitation professionals act when faced with the Great East Japan earthquake and disaster? Descriptive epidemiology of disability and an interim report of the relief activities of the ten Rehabilitation-Related Organizations. J Rehabil Med. 2012; 44: 421-428. doi: 10.2340/16501977-0957
221. Ebihara S, Ebihara T, Kohzuki M. Effect of aging on cough and swallowing reflexes: implications for preventing aspiration pneumonia. Lung. 2012; 190: 29-33. doi: 10.1007/s00408-011-9334-z
222. Ebihara S, Nikkuni E, Ebihara T, Sakamoto Y, Freeman S, Kohzuki M. Effects of olfactory stimulation on gait performance in frail older adults. Geriatr Gerontol Int. 2012; 12: 567-568. doi: 10.1111/j.1447-0594.2011.00801.x
223. Ebihara S, Niu K, Ebihara T, et al. Impact of Blunted Perception of Dyspnea on Medical Care Use and Expenditure, and Mortality in Elderly People. Front Physiol. 2012; 3: 238. doi: 10.3389/fphys.2012.00238
224. Miura M, Seki K, Ito O, Handa Y, Kohzuki M. Electrical stimulation of the abdomen preserves motor performance in the inactive elderly: a randomized controlled trial. Tohoku J Exp Med. 2012; 228: 93-101. doi: http://dx.doi.org/10.1620/tjem.228.93
225. Miura M, Seki K, Ito O, Handa Y, Kohzuki M. Functional Changes in the care-needing elderly after surface electrical stimulation to the abdomen. J Jpn Phys Ther Assoc. 2012; 15: 15-20. doi: http://dx.doi.org/10.1298/jjpta.Vol15_003
226. Muroya Y, Ito O, Ron R, et al. Disorders of fatty acid metabolism in the kidney of puromycin aminonucleoside-induced nephrotic rats. Am J Physiol Renal Physiol. 2012; 303: F1070-F1079. doi: 10.1152/ajprenal.00365.2011
227. Sakamoto Y, Ebihara S, Ebihara T, et al. Fall prevention using olfactory stimulation with lavender odor in elderly nursing home residents: a randomized controlled trial. J Am Geriatr Soc. 2012; 60: 1005-1011. doi: 10.1111/j.1532-5415.2012.03977.x
228. Kanezaki M, Ebihara S, Gui P, Ebihara T, Kohzuki M. Effect of cigarette smoking on cough reflex induced by TRPV1 and TRPA1 stimulations. Respir Med. 2012; 106: 406-412. doi: 10.1016/j.rmed.2011.12.007
229. Gui P, Ebihara S, Kanezaki M, et al. Urge-to-cough and dyspnea conceal perception of pain in healthy adults. Respir Physiol Neurobiol. 2012; 181: 214-219. doi: 10.1016/j.resp.2012.03.010
230. Kashiwazaki N, Ebihara S, Gui P, et al. Inhibitory effect of cervical trachea and chest wall vibrations on cough reflex sensitivity and perception of urge-to-cough in healthy male never-smokers.  Cough. 2013; 9(1): 22. doi:10.1186/1745-9974-9-22
231. Ebihara S, Ebihara T, Gui P, Osaka K, Sumi Y, Kohzuki M. Thermal Taste and Anti-Aspiration Drugs: a Novel Drug Discovery against Pneumonia.  Curr Pharm Des. 2013.
232. Ito D, Ito O, Mori N, et al. Exercise training upregulates nitric oxide synthases in the kidney of rats with chronic heart failure. Clin Exp Pharmacol Physiol. 2013; 40(9): 617-625. doi: 10.1111/1440-1681.12130
233. Ebihara S, Shannon F, Sakamoto Y, Ebihara T, Kohzuki M. Response letter to Lakin and Doe. J Am Geriatr Soc. 2013; 61(2): 313-314. doi: 10.1111/jgs.12108
234. Ito D, Ito O, Cao P, et al. Effects of exercise training on nitric oxide synthase in the kidney of spontaneously hypertensive rats. Clin Exp Pharmacol Physiol. 2013; 40(2): 74-82. doi: 10.1111/1440-1681.12040
235. Kohzuki M、Sakata Y, Mori N, Ebihara S, Ito S. Renal rehabilitation in patients with chronic kidney disease. Proceedings of the 7th World Congress of the International Society of Physical and Rehabilitation Medicine. 2013; 5-6.
236. Kohzuki M, Dobsak P, Magasaka M, Sakata Y, Ito S. Electrical stimulation of skeletal muscles and aerobic training in patients with heart failure. Proceedings of the 7th World Congress of the International Society of Physical and Rehabilitation Medicine. 2013; 63-64.
237. Miura M, Nagasaka M, Ito O, Kawai Y, Kohzuki M. Short term and long term effects of lower body positive pressure (LBPP) exercise for late elderly patients. Proceedings of the 7th World Congress of the International Society of Physical and Rehabilitation Medicine. 2013; 139-140.
238. Suzuki F, Ito O, Mori N, et al. Effect of cardiac rehabilitation on exercise tolerance, instrumental activities of daily living (IADL) and quality of life (QOL) in severe heart failure treated with implantable left ventricular device (LVAD). Proceedings of the 7th World Congress of the International Society of Physical and Rehabilitation Medicine. 2013; 141-143.
239. Sakata Y, Ito O, Watanabe H, Kohzuki M. The present situation of phase II cardiac rehabilitation for acute myocardial infarction at clinics in Japan. Proceedings of the 7th World Congress of the International Society of Physical and Rehabilitation Medicine. 2013; 143-144.
240. Ito K, Ebihara S, Gui P, Kashiwazaki N, Sato R, Kohzuki M. Pulmonary rehabilitation and gustation in patients with chronic obstructive pulmonary disease. Proceedings of the 7th World Congress of the International Society of Physical and Rehabilitation Medicine. 2013; 190-191.
241. Miura M, Ito O, Nagasaka M, Kohzuki M. Effects of electrical stimulation to skeletal muscle and exercise on the autonomic nervous activity. Proceedings of the 7th World Congress of the International Society of Physical and Rehabilitation Medicine. 2013; 192.
242. Sakai H, Kohzuki M, Kamide N, Jia T, Monma S, Ichie M. Geriatric rehabilitation in elderly people: relationship between depression and attitude/habituation to music. Proceedings of the 7th World Congress of the International Society of Physical and Rehabilitation Medicine. 2013; 200-201.
243. Kakihana T, Ito O, Suzuki F, Kohzuki M. Effect of exercise training for intermittent claudication due to incomplete persistent sciatic artery. Proceedings of the 7th World Congress of the International Society of Physical and Rehabilitation Medicine. 2013; 202-203.
244. Tanaka N, Miura M, Nagasaka M, Iguchi M, Ito O, Kohzuki M. Electric stimulation to the abdomen preserves activities of the elderly with chronic indwelling urinary catheter. Proceedings of the 7th World Congress of the International Society of Physical and Rehabilitation Medicine. 2013; 208.
245. Jia T, Miura M, Ito O, Nagasaka M, Rong R, Kohzuki M. Effects of music therapy and combination therapy on autonomic nervous activity. Proceedings of the 7th World Congress of the International Society of Physical and Rehabilitation Medicine. 2013; 209.
246. Tamura Y, Mori N, Gui P, et al. Comparison of the waiting period to begin rehabilitation between in Japan and China with the cerebral infarction. Proceedings of the 7th World Congress of the International Society of Physical and Rehabilitation Medicine. 2013; 246.
247. Mori N, Kashiwazaki N, Ito K, et al. Exercise performance after the radiofrequency catheter ablation. Proceedings of the 7th World Congress of the International Society of Physical and Rehabilitation Medicine. 2013; 280-281.
248. Kohzuki M. The significance of comprehensive rehabilitation. Total Rehabilitation Research. 2014 ; 1: 1-11.
249. Kohzuki M. Pulmonary rehabilitation in multimorbidity and multiple disabilities. Pulm Res Respir Med Open J. 2015; 2(2): e1-e2. doi: 10.17140/PRRMOJ-2-e001
250. Kohzuki M, Ebihara S. Taste sensitivity and nutrition in COPD rehabilitation. Pulm Res Respir Med Open J. 2016; 3(1): e1-e2. doi: 10.17140/PRRMOJ-3-e004