Joseph Shiu Kwong Kwan, MB ChB, MPhil, MD, FRCP

Clinical Associate Professor
Department of Geriatric Medicine
University of Hong Kong
102 Pok Fu Lam Road, Hong Kong


Dr. Joseph is a UK-trained Geriatrician. After gradating from Bristol Medical School in 1994, he went on to qualify from 4 other Universities including MPhil from Southampton University, MD from Edinburgh University, and Clinical Neurology from UCL. He was a Consultant Geriatrician for 8 years in the UK before returning to HKU as the Clinical
Associate Professor at the HKU. He also works as a Consultant at Queen Mary Hospital and Grantham Hospital. His academic research focuses on improving the lives of older people, including physical, cognitive and psychosocial independence, and a good quality of life. His current research portfolio concentrates on two main themes: a) aging brain from stroke and dementia; and b) aging muscle its impact on frailty and function. He is a strong advocate for ethical and humanistic care for the old and vulnerable people in the Society, and his motto is Happy Aging, Healthy Aging.

Research Interest

His research interests includes: Aging brain: vascular and Alzheimers dementia, Aging muscles: sarcopenia, Frailty in old age, Geroscience: relationship between biological aging and age-related diseases, Evidence-based gerontology and geriatric medicine, Health, human rights and humanistic care and Quality of life.

Scientific Activities


• (2014-now)- Member of the Medical Humanities Planning Group, University of HK
• (2014-now)- Organiser of the undergraduate teaching for Geriatric Medicine, University of HK
• (2014-now)- Editorial Board for the Journal of Heart Surgery and Treatment
• (2014-now)- Sentinel Reader in Evidence-Based Medicine for MORE (McMaster Online Rating of Evidence)
• (2014-now)- Contributor to the HK Geriatrics Society Curriculum in Geriatric Medicine, HK
• (2013-now)- MRCP and PACES Examiner, Royal College of Physicians London, UK
• (2012-3)- Consultant Representative, Cardiovascular Clinical Commissioning Programme, Dorset, UK
• (2011-3) – Consultant Representative, Stroke Specialist Training Committee, Wessex Deanery, UK
• (2011-3)- Consultant Representative, South West Stroke Research Network Management Board, UK
• (2010-2) – Head of Department, Department of Stroke Medicine, Royal Bournemouth Hospital, UK
• (2009-11)- Medical Director of Regional Stroke Network, Dorset, UK


1. Sykes L, Wood E, Kwan JSK. Antiepileptic drugs for the primary and secondary prevention of seizures after intracranial venous thrombosis. The Cochrane Database of Systematic Reviews. 2014; 8: CD005501.
2. Shea YF, Mok WWY, Chan JFW, Kwan JSK. A hidden cause of recurrent asthmatic attacks. J Am GeriatrSoc.2014; 62(7): 1408-1409. doi: 10.1111/jgs.12901.
3. Shea YF, Chan TC, Chang SKR, Hon FKS, Kwan JSK, Chu LW. Rapidly progressive ataxia during rehabilitation and a difficult road to diagnosis. J Am GeriatrSoc .2014; 62(8): 1609-1610. doi: 10.1111/jgs.12955
4. Sykes L, Wood E,Kwan J. Antiepileptic drugs for the primary and secondary prevention of seizures after stroke (Update). The Cochrane Database of Systematic Reviews. 2014; 1: CD005398. doi: 10.1002/14651858.CD005398.pub2
5. Kwan J, Horsfield G, Bryant T, et al. IL6 is a predictive biomarker for stroke associated infection and future mortality in the elderly after an ischaemic stroke. Experimental Gerontology. . 2013; 48(9): 960-965. doi: 10.1016/j.exger.2013.07.003
6. Poynter L, Kwan J, Vassallo M. How does cognitive impairment impact on functional improvement following the rehabilitation of elderly patients? International J Clin Practice .2013; 67(8): 811-815. doi: 10.1111/ijcp.12161
7. Marigold R, Tiwari D, Günther A, Kwan J. Antiepileptic drugs for the primary and secondary prevention of seizures after subarachnoid haemorrhage. The Cochrane Database of Systematic Reviews .2013 ; 6: CD008710. doi: 10.1002/14651858.CD008710.pub2
8. Kwan J, Pickering RM, Kunkel D, et al. Impact of stroke-associated infection on long term survival: a cohort study. J NeurolNeurosurg Psychiatry .2013; 84(3): 297-304. doi: 10.1136/jnnp-2012-302552
9. Kwan J. Thrombolysis. In: Oxford Desk Reference: Oxford University Press. Geriatric Medicine. .2012; 492-493.
10. Poynter L, Kwan J, Ahie Sayer A, Vassallo M. Does cognitive impairment affect rehabilitation outcome? J Am GeriatrSoc.2011; 59(11): 2108-2111. doi: 10.1111/j.1532-5415.2011.03658.x
11. Jupp B, Mallela SK, Kwan J, Allen S, Sharma JC, Vassallo M. Development and evaluation of the GEMS (gait, eyesight, mental state, sedation) tool as an aid to predict outcome after hospitalisation. Geriatrics and Gerontology International .2011; 11(1): 8-15. doi: 10.1111/j.1447-0594.2010.00626.x
12. Townend E, Tinson D, Kwan J, Sharpe M. Feeling sad and useless: an investigation into personal acceptance disability and its association with depression following stroke. Clinical Rehabilitation .2010; 24(6): 555-564. doi: 10.1177/0269215509358934
13. Kwan J. Predicting the risk of post-stroke epilepsy – why and how? Nature Reviews Neurology 2010; 6: 532-533. doi: 10.1038/nrneurol.2010.140.
14. Vassallo M, Mathie L, Sharma JC, Kwan J, Allen S. Fall risk factors in elderly patients with cognitive impairment on rehabilitation wards. Geriatrics and Gerontology International .2009; 9(1): 41-46. doi: 10.1111/j.1447-0594.2008.00506.x.
15. Englyst N, Horsfield G, Kwan J, Byrne C. Aspirin resistance is associated with inflammation, ischaemic stroke severity, and poorer functional outcome at six months. Journal of Cerebral Blood Flow and Metabolis .2008; 28(6): 1196-1203. doi: 10.1038/jcbfm.2008.9
16. Kwan J, Jenkinson D, Vassallo M, Englyst N, Perry VH. System infections after acute stroke. Aging Health. 2008; 491: 85-94.
17. Vassallo M, Mathie L, Sharma JC, Kwan J, Allen S. Falls risk assessment tools compared with clinical judgement: an evaluation in a rehabilitation ward. Age Ageing. 2008; 37: 277-281.
18. Abbas M, Guenther A, Galantucci S, et al. Microbial risk factors of cerebrovascular diseases: potential therapeutic options. The Open Neurology Journal. 2008; 2: 20-24.
19. Kwan J, Guenther A. Antiepileptic drugs for the primary and secondary prevention of seizures after intracranial venous thrombosis. The Cochrane Database of Systematic Reviews.2006, Issue 3.
20. Kwan J, Hand P, Dennis M, Sandercock P. Early stroke progression in the acute recovery period – clinical characteristics and impact on outcome. Quarterly J Medicine. 2006; 99: 625-633.
21. Townend E, Tinson D, Kwan J, Sharpe M. Fear of recurrence and beliefs about preventing recurrence in persons who have suffered a stroke. J Psychosomatic Res. 2006; 61(6): 747-55. doi:
22. Hand P, Kwan J, Lindley R, Dennis M, Wardlaw J. Improving the bedside assessment of suspected stroke – The Brain Attack Study. Stroke. 2006; 37: 769-775.
23. Hand P, Haisma J, Kwan J, et al. Inter-observer agreement for the clinical assessment of brain attack. Stroke. 2006; 37: 776-780.
24. Kwan J, Hand P, Sandercock P. A systematic review of the effectiveness of interventions to improve the efficiency of delivering thrombolysis for acute stroke. Quarterly Journal of Medicine. 2004; 97: 273-279.
25. Kwan J, Hand P, Sandercock P. A systematic review of barriers to efficient acute stroke care. Age Ageing. 2004; 33(2): 116-121.
26. Kwan J, Hand P, Dennis M, Sandercock P. Effects of introducing an integrated care pathway in an acute stroke unit. Age Ageing. 2004; 33: 362-367.
27. Stone J, Townend E, Kwan J, Haga K, Dennis MS, Sharpe M. Personality change after stroke: some preliminary observations. J NeurolNeurosurg Psychiatry. 2004; 75(12): 1708-1713. doi: 10.1136/jnnp.2004.037887
28. Sandercock P, Berge E, Dennis M, et al. Cost-effectiveness of thrombolytic with recombinant tissue plasminogen activator (rt-PA) for acute ischaemic stroke in the NHS. Stroke. 2004; 35(6): 1490-1498.
29. Kwan J, Lunt M, Jenkinson D. Assessing dynamic cerebral autoregulation after stroke using a novel technique of combining transcranial Doppler ultrasonography and rhythmic handgrip. Blood Pressure Monitoring.2004; 9(1): 3-8.
30. Wing-hang T, Hon-ming M, Jenny SW L, Elsie H, Jean W, Joseph SK K. Quality of care for older patients with non-cancer diagnoses under the end-of-life care program. Palliat Med Hosp Care Open J. 2015; 1(3): 59-65. doi: : 10.17140/PMHCOJ-1-111