Jacintha O. Sullivan, PhD

Associate Professor
Department of Surgery
Institute of Molecular Medicine
Trinity Centre for Health Sciences
St James Hospital
Dublin 8, Ireland


Dr. O. Sullivan was appointed as Associate Professor in the Department of Surgery, St. Jamess Hospital / TCD in 2010. Jacintha graduated from University College Dublin in 1995, with a first class honours degree in Cell Biology and Molecular Genetics. She then carried out her Ph.D. training at the Adrinodack Biomedical Research Institute, Lake Placid, New York and at the University of Notre Dame, Indiana in cancer cell biology. In 2000, she moved to the University of Washington, Seattle as a NIH funded fellow where she investigated how genomic instability events are crucial in driving disease progression in inflammatory diseases. In 2003, Jacintha returned to Dublin to the Centre for Colorectal Disease, St. Vincents University Hospital as a senior scientist to work with a multidisciplinary colorectal cancer team and to establish a translational colorectal cancer research program. Currently she directs two upper GI research programs in Barretts Oesophagus and Colorectal Cancer in the Department of Surgery, St. Jamess Hospital / TCD in collaboration with her surgical and clinical colleagues.

Research Interest

Her research interests include: Cellular instability and GI disease progression, Drug screening to search for new therapeutics, The role of the tumour micro environment in modulating disease progression and treatment sensitivity in GI cancers.

Scientific Activities

She has received grant funding from the Health Research Board, Irish Cancer Society and Science Foundation Ireland and from different industry sponsors. She has acted as a council member of the Irish Association for Cancer Research (IACR) from 2008-2012 and has been elected as honorary secretary for (2012-2015). She has supervised many MD, master and PhD thesis to completion.


Dr. O. Sullivan has established a strong scientific track record in the field of gastrointestinal cancers and inflammatory conditions with publications (66 in total) in high impact journals such as Nature Genetics, Human Molecular Genetics and Journal of Clinical Oncology.


1. Phelan JJ, O’Hanlon C, Reynolds JV, O’Sullivan J. The role of energy metabolism in driving disease progression in inflammatory, hypoxic and angiogenic microenvironments. Gastro Open J. 2015; 1(2): 44-58. doi: 10.17140/GOJ-1-108