What Impact for Sex Difference on Immune Thrombocytopenic Purpura?

Abstract

Despite the progress in medicine the impact of gender on many diseases remains 
unknown or unstudied. In this context, it seemed appropriate to us, with a bit of provocation, to 
study the impact of gender on Immune Thrombocytopenic Purpura (ITP).
 ITP, currently also known as primary immune thrombocytopenia, is an autoimmune 
disorder that results in acute or chronic thrombocytopenia and that may potentially lead to a 
life-threatening hemorrhagic event.1
 Major advances in our understanding of the pathophysiology of ITP have been done 
last years (evidence of anti-platelet antibodies and the relative failure of bone marrow platelet 
production),2 but the diagnosis of ITP still is based on exclusion