A Noteworthy Case of Myasthenic Crisis Induced by Levofloxacin
Keywords:
Myasthenia gravis; Levofloxacin, Fluoroquinolones, Neuromuscular junction, Myasthenic crisis, Myasthenia Gravis Foundation of America (MGFA) clinical classification, Antibiotic-induced exacerbation, Ocular muscle weakness, Respiratory muscle involvement, Treatment strategies, Molecular mechanisms, Adverse drug reactions, The coding symbols for a thesaurus of adverse reaction terms ( COSTART) frequency classificationAbstract
This case report discusses a patient with a past medical history of Myasthenia gravis who was admitted to the hospital for
community-acquired pneumonia and was then sent into a myasthenic crisis secondary to treatment with Levofloxacin. Although
Levofloxacin can be effective at resolving community-acquired pneumonia, this antibiotic can precipitate muscular pathologies
in certain population subsets. This is an interesting case of an acute myasthenic crisis being induced by Levofloxacin, leading the
patient into acute hypoxic respiratory failure. It is critical to thoroughly consider, and if possible, avoid, any class of medications
that may affect muscular function in individuals with myasthenia gravis.