Erdim Sertoglu, MD

Assistant Professor
Department of Medical Biochemistry
Gulhane Military Medical Academy
Haydarpasa Training Hospital
Istanbul, Turkey

 

Biography

EDUCATIONAL QUALIFICATIONS

• (1999-2005) MD degree, Gulhane School of Medicine, Ankara, Turkey
• (2004-2005) Internship, Gulhane School of Medicine, Ankara, Turkey

PROFESSIONAL EXPERIENCE

• (2005-2006) Physician, Gulhane School of Medicine, Ankara, Turkey
• (2006-2008) Chief Physician, Turkish Armed Forces, Bilecik, Turkey
• (2008-2012) Research Assistant, Gulhane School of Medicine, Department of Biochemistry and Clinical Biochemistry, Ankara, Turkey
• (2012-2013) Specialist, Laboratory Director, Ankara Beytepe Military Hospital, Medical Biochemistry Laboratory, Ankara, Turkey
• (2013-2015) Specialist, Laboratory Director, Ankara Mevki Military Hospital, Anittepe Dispensary, Medical Biochemistry Laboratory, Ankara, Turkey
• (2015-2015) Specialist, Laboratory Director, Elazig Military Hospital, Medical Biochemistry Laboratory, Elazig, Turkey
• (2015-Present) Assistant Professor, Gulhane Military Medical Academy, Haydarpasa Training Hospital, Department of Medical Biochemistry, Istanbul, Turkey

Research Interest

His present research interests include: Carrying out a number of studies specifically on non-alcoholic fatty liver disease, fatty acid metabolism and LC-MS/MS-based screening.

Scientific Activities

AWARDS

• Certificate of Experimental Animal Use (GATA Center for Research and Development, Ankara, 2009)
• Certificate of Basic Cell Culture and Stem Cell Course

Publications

1. Sertoglu E, Kayadibi H, Uyanik M. Important Issues in Determining the Cut-offs for Liver Fibrosis Index. J Clin Gastroenterol. 2014; 49(1): 90-91. doi: 10.1097/MCG.0000000000000172.
2. Sertoglu E, Uyanik M, Kayadibi H, Tapan S. Erythrocyte Membrane Fatty Acids May be Superior to Plasma Fatty Acids in Patients With Type 2 Diabetes. Metabolism. 2014; S0026-0495(14): 00360-00366. doi: 10.1016/j.metabol.2014.11.003.
3. Ozgonul C, Sertoglu E, Gokce G. Accurate Use of Neutrophil/Lymphocyte Ratio in Patients With Keratoconus. Cornea. 2014. doi: 10.1097/ICO.0000000000000321
4. Sertoglu E, Uyanik M, Kayadibi H. Assessment of the relationship between neutrophil-lymphocyte ratio and hearing loss of diabetics. Eur Arch Otorhinolaryngol. 2014. doi: http://dx.doi.org/10.1007/s00405-013-2734-3.
5. Sertoglu E, Kayadibi H, Uyanik M. Proper cut-off points to distinguish patients with NASH from non-NASH. Eur J Intern Med. 2014. S0953-6205(14):00326-4. doi: 10.1016/j.ejim.2014.10.025
6. Sertoglu E, Uyanik M, Kayadibi H. A Biochemical View: Vitamin D levels do not affect IVF outcomes following the transfer of euploid blastocysts. Am J Obstet Gynecol. 2014; S0002-9378(14): 02287-X. doi: http://dx.doi.org/10.1016/j.ajog.2014.11.022
7. Sertoglu E, Kayadibi H, Uyanik M. A biochemical view: Increase in polyunsaturated fatty acid ω-6/ω-3 ratio in relation to hepatic steatosis in patients with non-alcoholic fatty liver disease. J Diabetes Complications. 2014; S1056-8727(14): 00319-5. doi: 10.1016/j.jdiacomp.2014.10.005
8. Sertoglu E, Uyanik M, Kayadibi H, Tapan S. Use of proper diagnostic methods will provide more reliable results. Steroids. 2014; S0039-128X(14): 00273-00276. doi: 10.1016/j.steroids.2014.10.006
9. Sertoglu E, Kayadibi H, Uyanik M. Some important points for the selection and exclusion of patients with non-alcoholic fatty liver disease. Scand J Gastroenterol. 2014; 1: 1-2. doi: 10.3109/00365521.2014.983158
10. Kayadibi H, Sertoglu E, Uyanik M. Important issues in studies dealing with total homocysteine. Transplantation. 2014; 98(11): e89. doi: 10.1097/TP.0000000000000492.
11. Uyanik M, Sertoglu E, Kayadibi H, et al. Comparison of blood gas, electrolyte and metabolite results measured with two different blood gas analyzers and a core laboratory analyzer. Scand J Clin Lab Invest. 2014; 28: 1-9. doi: 10.3109/00365513.2014.981854
12. Coban M, Sertoglu E. Should the neutrophil-lymphocyte ratio be used as a noninvasive marker? Eur J Gastroenterol Hepatol. 2014; 27(1): 108. doi: 10.1097/MEG.0000000000000235.
13. Tapan S, Sertoglu E. Key Points on The Use of Neutrophil to Lymphocyte Ratio To Predict Mortality in Patients Listed For Liver Transplantation. Liver Int. 2014. doi: 10.1111/liv.12747. doi: 10.1111/liv.12747
14. Sertoglu E, Kayadibi H, Uyanik M. Biochemical view: “Red blood cell distribution width as a useful indicator to predict systemic vasculitis in patients with cutaneous vasculitis”. Rheumatol Int. 2014. doi: http://dx.doi.org/10.1007/s00296-014-3144-6.
15. Tapan S, Sertoglu E. Importance Of Confounding Factors in Assessing Fatty Acid Compositions in Patients With Nonalcoholic Steatohepatitis. Liver Int. 2014. doi: 10.1111/liv.12739. doi: 10.1111/liv.12739
16. Uyanik M, Sertoglu E, Serdar MA, Aydin FN, Ozgurtas T, Kurt I. Two Cases of the Same Family with the Unusual Elevation of CA19-9 Levels. Acta Med Port. 2014; 27(5): 657-660.
17. Kayadibi H, Sertoglu E, Uyanik M. Evaluation of Relationship Between CA-125 Levels and Ascites in Patients with Liver Cirrhosis. J Coll Physicians Surg Pak. 2014; 24(11): 873-874. doi: 11.2014/JCPSP.873874.
18. Uyanik M, Sertoglu E, Kayadibi H. Patient selection bias may derive from the improper usage of diagnostic methods. Climacteric. 2014; 17(6): 720. doi: 10.3109/13697137.2014.974534.
19. Kayadibi H, Sertoglu E, Uyanik M. Commentary on “Simple non-invasive biomarkers of advanced fibrosis in the evaluation of non-alcoholic fatty liver disease”. Gastroenterol Rep (Oxf). 2014; 2(4): 325. doi: 10.1093/gastro/gou064.
20. Ozgonul C, Sertoglu E. Accurate Use of Neutrophil/Lymphocyte Ratio in Patients with Age-related Macular Degeneration. Ocul Immunol Inflamm. 2014; 27: 1-2. doi: 10.3109/09273948.2014.970281
21. Sertoglu E, Kayadibi H, Uyanik M. Is single red cell distribution width without iron, folic acid and vitamin B12 enough to decide? Hepatol Res. 2014; 44(13): 1371. doi: 10.1111/hepr.12371
22. Gunes O, Tascilar E, Sertoglu E, et al. Associations between erythrocyte membrane fatty acid compositions and insulin resistance in obese adolescents. Chem Phys Lipids. doi: 2014; 184C: 69-75. doi: 10.1016/j.chemphyslip.2014.09.006
23. Kayadibi H, Sertoglu E, Uyanik M, Tapan S. Is increased red cell distribution width an indicating marker of nonalcoholic steatohepatitis and fibrotic stage? World J Gastroenterol. 2014; 20(35): 12711-12712. doi: 10.3748/wjg.v20.i35.12711.
24. Coban M, Sertoglu E, Kayadibi H. Can indirect non-invasive markers or models replace liver biopsy? Liver Int. 2014. doi: 10.1111/liv.12686
25. Sertoglu E, Kayadibi H, Uyanik M. Importance of Combined Fibrosis Indices in Chronic Hepatitis B Patients With Low Viremia. J Clin Gastroenterol. 2014.
26. Kayadibi H, Sertoglu E, Uyanik M. Plasma total homocysteine levels in diabetic retinopathy. Biomed Res Int. 2014; 2014: 758634. doi: 10.1155/2014/758634.
27. Meric C, Sonmez A, Aydogdu A, et al. Osteoprotegerin, fibroblast growth factor 23, and vitamin d3 levels in male patients with hypogonadism. Horm Metab Res. 2014; 46(13): 955-958. doi: 10.1055/s-0034-1387789.
28. Coban M, Sertoglu E. Proving risk factors with laboratory data may be more valuable. Liver Int. 2014. doi: 10.1111/liv.12677.
29. Sertoglu E, Kayadibi H, Uyanik M. Accurate use of neutrophil to lymphocyte ratio in predicting prognosis of papillary thyroid carcinoma. World J Surg. 2014; 38(12): 3286-3287. doi: 10.1007/s00268-014-2725-6.
30. Coban M, Sertoğlu E. Identifying all At-Risk Patients for Clostridium difficile Infection. J Clin Gastroenterol. 2014.
31. Kayadibi H, Sertoglu E, Uyanik M. Laboratory assessment may be dependent on the time of liver biopsy. Liver Int. 2014. doi: 10.1111/liv.12654. doi: 10.1111/liv.12654
32. Sertoglu E, Kayadibi H, Uyanik M. Interfering parameters in nonalcoholic fatty liver disease fibrosis score. Liver Int. 2014. doi: 10.1111/liv.12650. doi: 10.1111/liv.12650
33. Coban M, Sertoglu E. Importance of Serum Alanine Aminotransferase Upper Normal Limit in Population-based Studies. J Clin Gastroenterol. 2014.
34. Uyanik M, Sertoglu E, Kayadibi H. Early diagnosis of autoimmune hepatitis on the basis of demographic and biochemical parameters. Eur J Gastroenterol Hepatol. 2014; 26: 1060-1061. doi: 10.1097/MEG.0000000000000155.
35. Sertoglu E, Kayadibi H, Uyanik M. Single parameter or index to predict liver injury? Eur J Gastroenterol Hepatol. 2014; 26: 1060. doi: 10.1097/MEG.0000000000000148.
36. Kayadibi H, Sertoglu E, Uyanik M, Tapan S. Neutrophil-lymphocyte ratio is useful for the prognosis of patients with hepatocellular carcinoma. World J Gastroenterol. 2014; 20: 9631-9632. doi: 10.3748/wjg.v20.i28.9631
37. Sertoglu E, Kayadibi H, Uyanik M. Detailed Evaluation of the Aspartate Aminotransferase/Platelet Ratio Index and Enhanced Liver Fibrosis Tests in Assessing Hepatic Fibrosis. J Clin Gastroenterol. 2014.
38. Sertoglu E, Kayadibi H, Uyanik M. Important issues for selecting patients with nonalcoholic fatty liver disease: a biochemical view. Eur J Gastroenterol Hepatol. 2014; 26(8): 937. doi: 10.1097/MEG.0000000000000137
39. Kayadibi H, Uyanik M, Sertoglu E. Regarding “Neutrophil-lymphocyte ratio as a predictor of cognitive dysfunction in carotid endarterectomy patients”. J Vasc Surg. 2014; 60(1): 270-271. doi: 10.1016/j.jvs.2014.03.276.
40. Kayadibi H, Sertoglu E, Uyanik M. Importance of the selected cut-offs for serum uric acid and lipids levels. Scientific World Journal. 2014; 2014: 746561. doi: 10.1155/2014/746561.
41. Uyanik M, Kayadibi H, Sertoglu E. An important issue in the calculation of PGAA for the diagnosis of fibrosis stage in patients with alcoholic liver disease. Eur J Gastroenterol Hepatol. 2014; 26: 815-816. doi: 10.1097/MEG.0000000000000123
42. Kayadibi H, Sertoglu E, Uyanik M. Is high RDW really closely associated with NAFLD? Eur J Gastroenterol Hepatol. 2014; 26(7): 815. doi: 10.1097/MEG.0000000000000112.
43. Kayadibi H, Sertoglu E, Uyanik M. Is hematocrit really associated with fibrosis in patients with nonalcoholic steatohepatitis? Eur J Gastroenterol Hepatol. 2014; 26(7): 814-815. doi: 10.1097/MEG.0000000000000110
44. Dogru T, Sertoglu E, Gurel H, Celebi G. Comment on Dalmas et al. Intima-media thickness in severe obesity: links with BMI and metabolic status but not with systemic or adipose tissue inflammation. Diabetes Care. 2014; 37(5): e118. doi: 10.2337/dc13-2730.
45. Kurt I, Sertoglu E, Okur I, et al. Serum dipeptidyl peptidase-IV: a better screening test for early detection of mucopolysaccharidosis? Clin Chim Acta. 2014; 431: 250-254. doi: 10.1016/j.cca.2014.02.012
46. Sertoglu E, Ercin CN, Celebi G, et al. The relationship of serum uric acid with non-alcoholic fatty liver disease. Clin Biochem. 2014; 47(6): 383-388. doi: 10.1016/j.clinbiochem.2014.01.029
47. Sertoglu E, Kurt I, Tapan S, et al. Comparison of plasma and erythrocyte membrane fatty acid compositions in patients with end-stage renal disease and type 2 diabetes mellitus. Chem Phys Lipids. 2014; 178: 11-17. doi: 10.1016/j.chemphyslip.2013.12.011
48. Sertoglu E, Uyanik M. Accurate use of neutrophil/lymphocyte ratio from the perspective of laboratory experts. Vasc Health Risk Manag. 2014; 10: 13-14. doi: 10.2147/VHRM.S56906.
49. Dogru T, Sertoglu E, Celebi G, Gurel H, Ercin CN. Endothelial dysfunction and carotid atherosclerosis in non-alcoholic fatty liver disease. Ups J Med Sci. 2014; 119: 58-59. doi: 10.3109/03009734.2013.852276.
50. Serdar M, Sertoglu E, Uyanik M, et al. Comparison of 8-hydroxy-2-deoxyguanosine (8-OHdG) levels using mass spectrometer and urine albumin creatinine ratio as a predictor of development of diabetic nephropathy. Free Radic Res. 2012; 46: 1291-1295. doi: 10.3109/10715762.2012.710902
51. Dogru T, Genc H, Tapan S, et al. Plasma fetuin-A is associated with endothelial dysfunction and subclinical atherosclerosis in subjects with nonalcoholic fatty liver disease. Clin Endocrinol (Oxf) . 2013; 78(5): 712-7. doi: 10.1111/j.1365-2265.2012.04460.x
52. Dogru T, Genc H, Tapan S, et al. Elevated asymmetric dimethylarginine in plasma: an early marker for endothelial dysfunction in non-alcoholic fatty liver disease? Diabetes Res Clin Pract. 2012; 96(1): 47-52. doi: 10.1016/j.diabres.2011.11.022.
53. Genc H, Dogru T, Tapan S, et al. Circulating vaspin and its relationship with insulin sensitivity, adiponectin, and liver histology in subjects with non-alcoholic steatohepatitis. Scand J Gastroenterol. 2011; 46(11): 1355-1361. doi: 10.3109/00365521.2011.603163
54. Serdar MA, Sertoğlu E, Uyanık M, Tapan S, Akın O, Cihan M. Determination of 5-fluorouracil and dihydrofluorouracil levels by using a liquid chromatography-tandem mass spectrometry method for evaluation of dihydropyrimidine dehydrogenase enzyme activity. Cancer Chemother Pharmacol. 2011; 68(2): 525-529. doi: 10.1007/s00280-010-1528-1
55. Tapan S, Dogru T, Kara M, et al. Circulating levels of interleukin-18 in patients with non-alcoholic fatty liver disease. Scand J Clin Lab Invest. 2010; 70(6): 399-403. doi: 10.3109/00365513.2010.500675.