Dirk M. Hermann, MD

Chair for Vascular Neurology and Dementia
Department of Neurology
University Hospital Essen (AöR)
Hufelandstraße 55
D-45122 Essen
Germany

 

Biography

Dr. Dirk M Hermann studied medicine at the University of Gießen, Germany. After completing postdoctoral fellowships at the Max Planck Institutes in Munich and Cologne, he pursued his clinical training at University Hospitals in Tübingen and Zurich. He is now the Chair for Vascular Neurology and Dementia, at the University Hospital Essen, working on neurovascular remodelling and brain plasticity with special focus on ischaemic stroke.

Research Interest

His expertise includes: Stroke, Neurodegeneration, Dementia, Neurogeriatrics, Neuroplasticity.

Scientific Activities

STROKE: BASIC / TRANSLATION RESEARCH

PATHOPHYSIOLOGY AND EXPERIMENTAL TREATMENT OF ISCHEMIC STROKE

Using experimental methods we investigate degenerative and restorative processes in the circulation disturbed brain. A particular focus of our work is the characterization of the role of the vasculature in stroke pathophysiology and the role of the neurovascular unit during the stroke function restitution. We explore basics of pharmacological therapies and evaluate novel , focused on function recovery treatment concepts.

BASICS NEUROPROTECTIVE STROKE THERAPIES IN HUMANS

Central Nervous effective drugs are lipophilic rule and therefore in principle be able to cross the blood -brain barrier. Their accumulation in brain tissue is , however, not determined solely by passive diffusion processes, but influenced by active transport processes. Our group examined the expression of drug transporters at the blood circulation disturbed blood-brain barrier and developed strategies to improve drug accumulation in stroke brain.

CEREBRAL MICROANGIOPATHY : BASIC / TRANSLATIONAL RESEARCH

PATHOPHYSIOLOGY AND EXPERIMENTAL TREATMENT OF CEREBRAL MICROANGIOPATHY

With the help of genetically modified animal models , we investigate damage processes that result in cerebral microangiopathy in damage to the brain parenchyma . Our attention is also here in the characterization of the interactions between the vascular system and brain parenchyma, where we try to use strategies aimed at stabilizing the vascular integrity and function to prevent the progression of microangiopathy and encephalopathy. We do these primarily pharmacological therapies.

PATHOGENESIS AND EARLY DIAGNOSIS OF VASCULAR DEMENTIA

Denial Elle disorders often manifest themselves initially in a preliminary stage with so-called mild cognitive impairment, which has already been noticed in many cases by the patients and their relatives. Using imaging methods (MRI) , blood tests ( DNA polymorphisms , protein assays) and vascular function tests, we examine the causes of vascular dementia and analyze surrogate marker , let those dementing diseases at an early stage (ie , in its preliminary stages ) to predict and influence . Attached to our group is our dementia and memory clinic.

Publications

ORIGINAL ARTICLES IN REFEREED JOURNALS

1. Peyron C, Luppi PH, Kitahama K, Fort P, Hermann DM, Jouvet M. Origin of the dopaminergic innervation of the rat dorsal raphe nucleus. Neuroreport. 1995; 6: 2527-2531.
2. Hermann DM, Luppi PH, Peyron C, Hinckel P, Jouvet M. Forebrain projections of the rostral nucleus raphe magnus shown by iontophoretic application of choleratoxin b in rats. Neurosci. Lett. 1996; 216: 151-154.
3. Mullington J, Hermann D, Holsboer F, Pollmächer T. Age dependent suppression of nocturnal growth hormone levels during sleep deprivation. Neuroendocrinology. 1996; 64: 233-241.
4. Pollmächer T, Mullington J, Korth C, et al. Diurnal variations in the human host response to endotoxin. J. Infect. Dis. 1996; 174: 1040-1045. doi: 10.1093/infdis/174.5.1040
5. Pollmächer T, Korth C, Schreiber W, Hermann D, Mullington J.Effects of repeated administration of granulocyte colony-stimulating factor G-CSF on neutrophil counts, plasma cytokine, and cytokine receptor levels.Cytokine. 1996; 8: 799-803.
6. Hermann DM, Luppi PH, Peyron C, Hinckel P, Jouvet M. Afferent projections to the rat nuclei raphe magnus, raphe pallidus and gigantocellular reticularis pars alpha demonstrated by iontophoretic application of choleratoxin subunit b. J. Chem. Neuroanat. 1997; 13: 1-21.
7. Fritze K, Wiessner C, Kuster N, et al. Effect of global system for communication microwave exposure on the genomic response of the rat brain. Neuroscience. 1997; 81: 627-639.
8. Hermann DM, Mullington J, Hinze-Selch D, Schreiber W, Galanos C, Pollmächer T. Endotoxin-induced changes in sleep and sleepiness during the day. Psychoneuroendocrinology. 1998; 23: 427-437. doi: http://dx.doi.org/10.1016/S0306-4530(98)00030-4
9. Hermann DM, Mies G, Hossmann KA. Effects of a traumatic neocortical lesion on cerebral metabolism and gene expression of rats. Neuroreport. 1998; 9: 1249-1253.
10. Hermann DM, Kuroiwa T, Ito U, Mies G. Expression of c-jun, hsp72 and gfap following repeated unilateral common carotid artery occlusion in gerbils – Correlates of delayed ischemic injury. Brain Res. 1998; 799: 35-43.
11. Hermann DM, Mies G, Hossmann KA. Effects of a traumatic neocortical lesion on cerebral metabolism and gene expression of rats. Neuro report. 1998; 9: 1917-1921.
12. Kilic E, Hermann DM, Hossmann KA. A reproducible model of thromboembolic stroke in mice. Neuroreport . 1998; 9: 2967-2970.
13. Schuld A, Mullington J, Hermann D, et al. Effects of granulocyte colony-stimulating factor on night sleep in humans. Am. J. Physiol. 1999; 276: 1149-1155.
14. Hermann DM, Mies G, Hossmann KA.Expression of c-fos, junB, c-jun, MKP-1 and hsp72 following traumatic neocortical lesions in rats – Relation to spreading depression. Neuroscience. 1999; 88: 599-608.
15. Hermann DM, Mies G, Hossmann KA. Biochemical changes and gene expression following traumatic brain injury: Role of spreading depression. Restor. Neurol. Neurosci. 1999; 14: 103-108.
16. Kilic E, Hermann DM, Hossmann KA. Recombinant tissue plasminogen activator reduces infarct size after reversible thread occlusion of middle cerebral artery in mice. Neuroreport. 1999; 10: 107-111.
17.Hermann DM, Mies G, Hossmann KA. Lesion-remote metabolic changes after neocortical cold injury in rats. Neuroreport. 1999; 10: 759-763.
18. Mies G, Hermann DM, Ganten U, Hossmann KA. Hemodynamic and metabolism in stroke-prone spontaneously hypertensive rats before manifestation of brain infarcts. J. Cereb. Blood Flow Metab. 1999; 19: 1238-1246. doi: 10.1097/00004647-199911000-00008
19. Mullington J, Korth C, Hermann DM, Orth A, Holsboer F, Pollmächer T. Dose-related effects of endotoxin on nocturnal sleep in humans.Am. J. Physiol. 2000; 278: R947-R955.
20. Schuld A, Mullington J, Friess E, et al. Changes in dehydroepiandrosterone DHEA and DHEA-sulfate plasma levels during experimental endotoxemia in healthy volunteers.J. Clin. Endocrinol. Metab. 2000; 85: 4624-4629. doi: http://dx.doi.org/10.1210/jcem.85.12.7055
21. Hermann DM, Mies G, Hata R, Hossmann KA. Microglial and astrocytic reactions prior to onset of thalamic cell death after traumatic lesion of the rat sensorimotor cortex. Acta Neuropathol. 2000; 99: 147-153.
22. Kilic E, Hermann DM, Hossmann KA. Recombinant tissue-plasminogen activator-induced thrombolysis after cerebral thromboembolism in mice. Acta Neuropathol. 2000; 99: 219-222.
23. Kuroiwa T, Mies G, Hermann D, Hakamata Y, Hanyu S, Ito U. Regional differences in the rate of energy impairment after threshold level ischemia for induction of cerebral infarction in gerbils. Acta Neuropathol. 2000; 100: 587-594.
24. Hata R, Maeda K, Hermann DM, Mies G, Hossmann KA. Dynamics of brain metabolism and gene expression after middle cerebral artery occlusion in mice. J. Cereb. Blood Flow Metab. 2000; 20: 306-315. doi: 10.1097/00004647-200002000-00012
25. Hata R, Maeda K, Hermann DM, Mies G, Hossmann KA. Evolution of brain infarction after transient focal cerebral ischemia in mice. J. Cereb. Blood Flow Metab. 2000; 20: 937-946.
26. Kuroiwa T, Ito U, Hakamata Y, Hanyu S, Mies G, Hermann D. Evolution of energy failure after repeated cerebral ischemia in gerbils. Acta Neurochir. 2000; 76: 43-46.
27. Hermann DM, Kuroiwa T, Hata R, Gillardon F, Ito U, Mies G. Expression of nuclear redox factor-1, p53-activated gene 608 and caspase-3 messenger RNAs following repeated unilateral common carotid artery occlusion in gerbils – Relationship to delayed cell injury and secondary failure of energy state. Neuroscience. 2001; 102: 779-787.
28. Hermann DM, Kilic E, Hata R, Hossmann KA, Mies G. Relationship between metabolic changes, gene responses and delayed cell death after mild focal cerebral ischemia in mice. Neuroscience. 2001; 102: 947-955.
29. Hermann DM, Kilic E, Kgler S, Isenmann S, Bähr M. Adenovirus-mediated GDNF and CNTF pretreatment protects against striatal injury following transient middle cerebral artery occlusion in mice. Neurobiol. Dis. 2001; 8:655-666.
30. Hermann DM, Kilic E, Kgler S, Isenmann S, Bähr M. Adenovirus-mediated glial cell line-derived neurotrophic factor GDNF expression protects against subsequent cortical cold injury in rats. Neurobiol. Dis. 2001; 8: 964-973.
31. Kilic E, Bähr M, Hermann DM. Effects of recombinant tissue-plasminogen activator after intraluminal thread occlusion in mice: Role of hemodynamic alterations. Stroke. 2001; 32: 2641-2647. doi: 10.1161/hs1101.097381
32. Kilic E, Hermann DM, Isenmann S, Bähr M. Effects of pinealectomy and melatonin on the retrograde degeneration of retinal ganglion cells in a novel model of intraorbital optic nerve transection in mice. J. Pineal Res. 2002; 32: 106-111. doi: 10.1034/j.1600-079x.2002.1823.x
33. Kilic E, Dietz G, Hermann DM, Bähr M. Intravenous TAT-Bcl-XL is protective after middle cerebral artery occlusion in mice. Ann. Neurol. 2002; 52; 617-622. doi: 10.1002/ana.10356
34. Kilic E, Hermann DM, Kgler S, Bähr M. Adenovirus-mediated Bcl-XL expression using a neuron-specific synapsin-1 promoter protects against disseminated neuronal injury and brain infarction following focal cerebral ischemia in mice. Neurobiol. Dis. 2002; 11: 275-284.
35. Hermann DM, Mies G, Hossmann KA. Expression of c-jun, mkp-1, caspase-3 and gfap mRNAs following cortical cold trauma in rats: Relationship to brain metabolism and delayed cell injury. Neuroscience. 2004; 123: 371-379.
36. Kilic E, Bassetti CL, Hermann DM. Recombinant tissue-plasminogen activator t-PA attenuates disseminate neuronal injury after mild episodes of middle cerebral artery MCA thread occlusion in mice. Neuroreport. 2004; 15: 687-689.
37. Kilic E, Yulug B, Hermann DM, Reiter RJ. Melatonin delivery reduces disseminate neuronal death after mild focal ischemia in C57BL/6j mice via inhibition of caspase-3 and is suitable as add-on treatment to tissue-plasminogen activator. J. Pineal Res. 2004; 36: 171-176.
38. Kilic E, Reiter RJ, Bassetti CL, Hermann DM. Prophylactic melatonin protects against focal cerebral ischemia in mice: Role of endothelin converting enzyme-1. J. Pineal Res. 2004; 37: 247-251. doi: 10.1111/j.1600-079X.2004.00162.x
39. Spaeth N, Wyss MT, Weber B, et al.Uptake of 18F-fluorocholine, 18F-fluoro-ethyl-L-tyrosine and 18F-fluoro-2-deoxyglucose in acute cerebral radiation injury in the rat: implications for the separation of radiation necrosis from tumor recurrence. J. Nucl. Med. 2004; 45:1931-1938.
40. Kilic E, Weishaupt J, Rohde G, et al. The superoxide dismutase1 SOD1 G93A mutation does not promote neuronal injury after transient focal brain ischemia und optic nerve transection in mice. Neuroscience. 2004; 128: 359-364.
41. Kilic E, Reiter RJ, Bassetti C, Hermann DM. Signal transduction pathways involved in melatonin-induced neuroprotection after focal cerebral ischemia in mice. J. Pineal Res. 2005; 38: 67-71. doi: 10.1111/j.1600-079X.2004.00178.x
42. Hermann DM, Bassetti C. Reversible opsoclonus following diphenhydramine misuse. Eur. Neurol. 2005; 53: 46-47. doi: 10.1159/000084266
43. Hermann DM, Fehr J, Bassetti C. Epstein Barr virus EBV associated T cell clonopathy mimicking lymphomatous meningitis. J. Neurol. 2005; 252: 736-737.
44. Kilic E, Matter C, Lscher TF, Bassetti C, Hermann DM. Aggravation of focal cerebral ischemia by tissue-plasminogen activator is reversed by HMG CoA reductase inhibitor, but does not depend on endothelial NO synthase. Stroke. 2005; 36: 332-336.
45, Kilic E, Soliz J, Bassetti C, Gassmann M, Hermann DM. Transgenic erythropoietin protects from axotomy-induced degeneration of retinal ganglion cells by activating ERK-1/-2. FASEB J. 2005; 19: 249-251.
46. Wang Y, Kilic E, Weber B, Bassetti C, Marti H, Hermann DM. VEGF overexpression induces post-ischaemic neuroprotection, but facilitates haemodynamic steal phenomena. Brain. 2005; 128: 52-63. doi: http://dx.doi.org/10.1093/brain/awh325
47. Kilic E, Reiter RJ, Bassetti CL, Hermann DM. Melatonin reverses t-PA-induced brain injury after intraluminal middle cerebral artery occlusion in mice: Role of Akt and inducible NO synthase. J. Pineal Res. 2005; 39: 151-155.
48. Kilic, Bassetti C, Kilic E, Xing H, Wang Z, Hermann DM. Post-ischemic delivery of the HMG-CoA reductase inhibitor rosuvastatin protects against focal cerebral ischemia in mice by mechanisms involving inhibition of extracellular-regulated kinase ERK-1/-2. Neuroscience. 2005; 106: 901-906.
49. Spudich A, Frigg R, Kilic E, B. et al. Aggravation of ischemic injury by prion protein deficiency following focal cerebral ischemia in mice: Role of ERK-1/-2 and STAT-1. Neurobiol. Dis. 2005; 20: 442-449.
50. Kilic E, Soliz J, Bassetti C, Gassmann M, Hermann DM. Erythropoietin protects from focal cerebral ischemia by a dual mechanism involving both ERK-1/-2 and Akt pathways. FASEB J. 2005; 19: 2026-2028.
51. Selic C, Siccoli MM, Hermann DM, Bassetti C. Blood pressure evolution after acute ischemic stroke in patients with and without sleep apnea. Stroke. 2005; 36: 2614-2618. doi: 10.1161/01.STR.0000189689.65734.a3
52. Kilic E, Bähr M, Hermann DM. Aggravation of focal cerebral ischemia by tissue-plasminogen activator is reversed by MK-801. Neurodegen. Dis. 2005; 2: 49-55.
53. Kilic E, Hermann DM. TAT-GDNF in neurodegenerative disease and ischemic stroke. CNS Drug Rev. 2005; 11: 353-362.
54. Spudich A, Kilic E, Xing H, Wunderli-Allenspach H, Bassetti CL, Hermann DM. Pharmacological inhibition of multidrug resistance transporter Mdr-1 facilitates neuroprotective therapies after focal cerebral ischemia. Nature Neurosci. 2006; 9: 487-488.
55. Kilic E, Wang Y, Bassetti C, Marti H, Hermann DM. The phosphatidylinositol-3 kinase/ Akt mediates VEGF s neuroprotective activity and induces blood brain barrier disturbance after focal cerebral ischemia. FASEB J. 2006; 20: 1185-1187. doi: 10.1096/fj.05-4829fje
56. Matter CM, Ma L, Von Lukovicz T, et al. Increased balloon-induced neointima in apolipoprotein E ApoE knockout mice – incremental effects of the ApoE gene and high-cholesterol diet. Stroke. 2006; 37: 2625-2632. doi: 10.1161/01.STR.0000241068.50156.82
57. Baumann CR, Kilic E, Werth E, Hermann DM, Tafti M, Bassetti C. Sustained non-rapid eye movement NREM sleep increase following striatal but not cortical middle cerebral artery infarcts in mice. Sleep. 2006; 29: 1339-1344.
58. Kilic E, Wang Y, Bassetti C, Marti H, Hermann DM. Transgenic VEGF protects from axotomy-induced degeneration of retinal ganglion cells by activating ERK-1/-2 and Akt pathways. J. Neurosci. 2006; 26: 12439-12446.
59. Hermann DM, Siccoli M, Kirov P, Gugger M, Bassetti C. Central periodic breathing during sleep in acute ischemic stroke. Stroke. 2007; 38: 1082-1084.
60. Soliz J, Soulage C, Hermann DM, Gassmann M. Acute and chronic exposure to hypoxia alters ventilatory pattern but not minute ventilation of mice overexpressing erythropoietin. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2007; 293: R1702-R1710.
61. Kilic E, Wippel A, Vogel P, et al. Poxvirus-derived cytokine response modifier A CrmA does not protect against focal cerebral ischemia in mice. Brain Res. 2007; 1185: 293-300. doi:
62. Hermann DM, Siccoli M, Wachter k, Mathis J, Achermann P, Bassetti C. Evolution of neurological, neuropsychological and sleep-wake disturbances in paramedian thalamic stroke. Stroke. 2008; 39: 62-68. doi: 10.1161/STROKEAHA.107.494955
63. Kilic E, Bacigaluppi M, Guo Z, et al. Delayed melatonin administration promotes neuronal survival, neurogenesis and motor recovery, and attenuates hyperactivity and anxiety after mild focal cerebral ischemia in mice. J. Pineal Res. 2008; 45: 142-148. doi: 10.1111/j.1600-079X.2008.00568.x
64. Hédou GF, Koshibu K, Farinelli M, et al. Protein phosphatase 1-dependent bidirectional synaptic plasticity controls ischemic recovery in the adult brain. J. Neurosci. 2008; 28: 154-162. doi: 10.1523/JNEUROSCI.4109-07.2008
65. Gao B, Kilic E, Baumann C, Hermann DM, Bassetti C. Gamma-hydroxybutyrate accelerates functional recovery after focal cerebral ischemia. Cerebrovasc. Dis. 2008; 26: 413-419. doi: 10.1159/000151683
66. Kilic E, Bassetti CL, Hermann DM. TLR-4 deficiency protects against focal cerebral ischemia and delayed neurodegeneration. Neurobiol. Dis. 2008; 31: 33-40.
67. Kilic E, Spudich A, Rentsch KM, et al. ABCC1: A gateway for pharmacological compounds to the ischaemic brain. Brain. 2008; 131: 2679-2689. doi: 10.1093/brain/awn222
68. Hermann DM, Barth A, Porchet F, Hess CW, Mumenthaler M, Bassetti C. Nocturnal positional lumboischialgia: Presenting symptom of lumbar spinal tumors. J. Neurol. 2008; 255: 1836-1837. doi: 10.1007/s00415-008-0998-0
69. Siccoli MM, Valko PO, Hermann DM, Bassetti C. Central periodic breathing during sleep in 74 patients with acute ischemic stroke – Neurogenic and cardiogenic factors. J. Neurol. 2008; 255: 1687-1692. doi: 10.1007/s00415-008-0981-9
70. Hermann DM, Jung HH, Bassetti C. Lateral medullary infarct with alternating and dissociated sensorimotor symptoms: Opalski s syndrome revisited. Eur. J. Neurol. 2009; 16: e72-e74.
71. Bacigaluppi M, Pluchino S, Kilic E, et al. Delayed systemic neural stem cell transplantation protects from ischemic brain injury via multiple mechanisms. Brain. 2009; 132(8): 2239-2251.
72. Kilic E, ElAli A, Bassetti C, Guo Z, Schwab ME, Hermann DM. Role of Nogo-A in neuronal survival in the reperfused ischemic brain. J. Cereb. Blood Flow Metab. 2010; 30: 969-984. doi: 10.1038/jcbfm.2009.268.
73. Zechariah A, ElAli A, Hermann DM. Combination of tissue-plasminogen activator with erythropoietin induces blood-brain barrier permeability, extracellular matrix disaggregation and DNA fragmentation after focal cerebral ischemia in mice. Stroke. 2010; 41: 1008-1012.
74. ElAli A, Hermann DM. Apolipoprotein E controls ATP-binding cassette transporters in the ischemic brain. Sci. Signal. 2010: 3: 72.
75. Doeppner TR, Kaltwasser B, ElAli A, Zechariah A, Hermann DM, Bähr M. Acute hepatocyte growth factor treatment induces long-term neuroprotection and stroke recovery via mechanisms involving neural precursor cell proliferation and differentiation. J. Cereb. Blood Flow Metab. 2011; 31: 1251-1262. doi: 10.1038/jcbfm.2010.211
76. Reitmeir R, Kilic E, Bacigaluppi M, et al. Post-acute delivery of erythropoietin induces stroke recovery by promoting peri-lesional tissue remodeling and contralesional pyramidal tract plasticity. Brain. 2011; 134: 84-99. doi: 10.1093/brain/awq344
77. ElAli A, Hermann DM. Liver X receptor activation enhances blood-brain barrier integrity in the ischemic brain and increases the abundance of ATP-binding cassette transporters ABCB1 and ABCC1 on brain capillary cells. Brain Pathol. 2012; 22: 175-187. doi: 10.1111/j.1750-3639.2011.00517.x
78. Hermann DM, Keyvani K, Van de Nes J, et al. Brain-reactive β-amyloid antibodies in primary CNS angiitis with cerebral amyloid angiopathy. Neurology. 2011; 77: 503-505. doi: 10.1212/WNL.0b013e318227b250
79. Doeppner TR, Bretschneider E, Doehring M, et al. Enhancement of endogenous neurogenesis in ephrin-B3 deficient mice after transient focal cerebral ischemia. Acta Neuropathol. 2011; 122: 429-442. doi: 10.1007/s00401-011-0856-5
80. ElAli A, Doeppner TR, Zechariah A, Hermann DM. Increased blood-brain barrier permeability and brain edema after focal cerebral ischemia induced by hyperlipidemia: Role of lipid peroxidation and calpain-1/2, matrix metalloproteinase-2/9, and RhoA overactivation. Stroke. 2011; 42: 3238-3244. doi: 10.1161/STROKEAHA.111.615559.
81. Kilic U, Yilmaz B, Ugur M, et al. Evidence that membrane-bound G protein-coupled melatonin receptors MT1 and MT2 are not involved in the neuroprotective effects of melatonin in focal cerebral ischemia. J. Pineal Res. 2012; 52: 228-235. doi: 10.1111/j.1600-079X.2011.00932.x
82. Patak P, Jin F, Schafer ST, Metzen E, Hermann DM. The ATP-binding cassette transporters ABCB1 and ABCC1 are not regulated by hypoxia in immortalised human brain microvascular endothelial cells. Exp. Transl. Stroke Med. 2011; 3: 12. doi: 10.1186/2040-7378-3-12
83. Reitmeir R, Kilic E, Reinboth BS, ElAli A, Zechariah A, Hermann DM. Vascular endothelial growth factor induces contralesional corticobulbar plasticity and functional neurological recovery in the ischemic brain. Acta Neuropathol. 2012; 123: 273-284.
84. Hasan MR, Herz J, Hermann DM, Doeppner TR. Visualization of macroscopic cerebral vessel anatomy – a new and reliable technique in mice. J. Neurosci. Meth. 2012; 204: 249-253. doi: 10.1016/j.jneumeth.2011.11.024.
85. Herz J, Reitmeir R, Hagen SI, et al. Intracerebroventricularly delivered VEGF promotes contralesional corticorubral plasticity after focal cerebral ischemia via mechanisms involving anti-inflammatory actions. Neurobiol. Dis. 2012; 45: 1077-1085. doi: 10.1016/j.nbd.2011.12.026
86. ElAli A, Urrutia A, Colado MI, Hermann DM. Apolipoprotein-E controls ATP-binding cassette transporters ABCB1 and ABCC1 on cerebral microvessels after methamphetamine intoxication. Stroke. 2012; 43: 1647-1653. doi: 10.1161/STROKEAHA.111.648923
87. Herring A, Donath A, Steiner KM, et al. Reelin depletion is an early phenomenon of Alzheimer s pathology. J. Alzheimer s Dis. 2012; 30: 963-979. doi: 10.3233/JAD-2012-112069
88. Doeppner TR, Ewert TAS, Herz J, et al. Transduction of neural precursor cells with TAT-Hsp70 chaperone: therapeutic potential against ischemic stroke after intrastriatal and systemic transplantation. Stem Cells. 2012; 30: 1297-1310. doi: 10.1002/stem.1098
89. Hermann DM, Gronewold J, Lehmann N, et al. Intima-media thickness predicts stroke risk in the Heinz Nixdorf Recall study in association with vascular risk factors, age and gender. Atherosclerosis. 2012; 224: 84-89.
90. Doeppner TR, Mlynarczuk-Bialy I, Kuckelkorn U, et al. The novel proteasome inhibitor BSc2118 protects against focal cerebral ischemia and promotes blood-brain-barrier integrity via HIF-1α accumulation and enhanced angioneurogenesis. Brain. 2012; 135: 3282-3297.
91. Jin F, Ji H, Jia C, et al. Synergistic antitumor effects of endostar in combination with oxaliplatin via inhibition of HIF and CXCR4 in the colorectal cell line SW1116. PLoS One. 2012; 7: e47161. doi: 10.1371/journal.pone.0047161
92. Urrutia A, Rubio-Araiz A, Gutierrez-Lopez MD, et al. A study on the effect of JNK inhibitor, SP600125, on the disruption of blood-brain barrier induced by methamphetamine. Neurobiol. Dis. 2013; 50: 49-58. doi: 10.1016/j.nbd.2012.10.006
93. Hermann DM, Gronewold J, et al. Coronary artery calcification is an independent stroke predictor in the general population. Stroke. 2013; 44: 1008-1013. doi: 10.1161/STROKEAHA.111.678078
94. Zechariah A, ElAli A, Doeppner TR, et al. VEGF promotes pericyte coverage of brain capillaries, improves cerebral blood flow during subsequent focal cerebral ischemia, and preserves the metabolic penumbra. Stroke. 2013; 44: 1690-1697. doi: 10.1161/STROKEAHA.111.000240
95. Zechariah A, ElAli A, Hagemann N, et al. Hyperlipidemia attenuates VEGF-induced angiogenesis, impairs cerebral blood flow and disturbs stroke recovery via reduced VEGF receptor-2 and -1 expression and decreased pericyte coverage of brain endothelial cells. Arterioscler. Thromb. Vasc. Biol. 2013; 33: 1561-1567.
96. Jin F, Hagemann N, Brockmeier U, Schäfer ST, Zechariah A, Hermann DM. LDL attenuates VEGF-induced angiogenesis via mechanisms involving VEGFR2 internalization and degradation following endosome-trans-Golgi network trafficking. Angiogenesis. 2013; 16: 625-637. doi: 10.1007/s10456-013-9340-2
97. Hasan MR, Herz J, Hermann DM, Doeppner TR. Intravascular perfusion of carbon black ink allows reliable visualization of cerebral vessels. J. Vis. Exp. 2013; 71. doi: 10.3791/4374
98. Seidel UK, Gronewold J, Volsek M, et al. The prevalence, severity, and association with HbA1c and fibrinogen of cognitive impairment in chronic kidney disease. Kidney Int. 2014; 85: 693-702.
99. Jin F, Hagemann N, Schäfer ST, Brockmeier U, Zechariah A, Hermann DM. SDF-1 restores angiogenesis synergistically with VEGF following LDL exposure: Role of CXCR4 internalization and degradation. Cardiovasc. Res. 2013; 100: 481-491. doi: 10.1093/cvr/cvt209.
100. Doeppner TR, Doehring M, Bretschneider E, et al. MicroRNA-124 protects against focal cerebral ischemia via mechanisms involving Usp14-dependent REST degradation. Acta Neuropathol. 2013; 126: 251-265. doi: 10.1007/s00401-013-1142-5
101. Doeppner TR, Kaltwasser B, Fengyan J, Hermann DM, Bähr M. TAT-Hsp70 induces neuroprotection against stroke via anti-inflammatory actions providing appropriate cellular microenvironment for transplantation of neural precursor cells. J Cereb Blood Flow Metab. 2013; 33: 1778-1788. doi: 10.1038/jcbfm.2013.126
102. Goebel S, Li Z, Vogelmann J, et al. The GPVI-Fc fusion protein Revacept improves cerebral infarct volume and functional outcome in stroke. PLoS One. 2013; 8: e66960. doi: 10.1371/journal.pone.0066960
103. Herz J, Hagen SI, Bergmller E, et al. Exacerbation of ischemic brain injury in hypercholesterolemic mice is associated with pronounced changes in peripheral and cerebral immune responses. Neurobiol Dis. 2014; 62: 456-468. doi: 10.1016/j.nbd.2013.10.022
104. Hoyo-Becerra C, Huebener A, Trippler M, et al. Concomitant interferon alpha stimulation and TLR3 activation induces neuronal expression of depression-related genes that are elevated in the brain of suicidal persons. PLoS One. 2013; 8: e83149. doi: 10.1371/journal.pone.0083149
105. Gronewold J, Hermann DM, Lehmann N, et al. Ankle-brachial index is an independent stroke predictor in the general population.Atherosclerosis. 2014; 233: 545-550. doi: http://dx.doi.org/10.1016/j.atherosclerosis.2014.01.044
106. Kara K, Gronewold J, Neumann T, et al. B-type natriuretic peptide predicts stroke of presumable cardioembolic origin in addition to coronary artery calcification.Eur J Neurol. 2014; 21: 914-921. doi: 10.1111/ene.12411
107. Seidel UK, Gronewold J, Volsek M, et al. Physical, cognitive and emotional factors contributing to quality of life, functional health and participation in community dwelling in chronic kidney disease.PLoS One. 2014; 9: e91176. doi: 10.1371/journal.pone.0091176
108. Tang WK, Hermann DM, Chen YK, et al. Brainstem infarcts predict REM sleep behavior disorder in acute ischemic stroke. BMC Neurol. 2014; 14: 88. doi: 10.1186/1471-2377-14-88
109. Gronewold J, Bauer M, Lehmann N, et al. Coronary artery calcification, intima-media thickness, and ankle-brachial index are complementary stroke predictors. Stroke. 2014; 45: 2702-2709. doi: 10.1161/STROKEAHA.114.005626
110. Doeppner TR, Kaltwasser B, Teli MK, Bretschneider E, Bähr M, Hermann DM. Effects of acute versus post-acute systemic delivery of neural progenitor cells on neurological recovery and brain remodeling after focal cerebral ischemia in mice. Cell Death Dis. 2014; 5: e1386. doi: 10.1038/cddis.2014.359
111. Hoyo-Becerra C, Liu Z, Yao J, et al. Rapid regulation of depression-associated genes in a new mouse model mimicking interferon-α-related depression in hepatitis C virus infection. Mol Neurobiol. 2014. doi: 10.1007/s12035-014-8861-z
112. Doeppner TR, Kaltwasser B, Bähr M, Hermann DM. Effects of neural progenitor cells on post-stroke neurological impairment-a detailed and comprehensive analysis of behavioral tests. Front Cell Neurosci. 2014; 8: 338.
113. Neumann J, Riek-Burchardt M, Herz J, et al. Very-late-antigen-4 VLA-4-mediated brain invasion by neutrophils leads to interactions with microglia, increased ischemic injury and impaired behavior in experimental stroke. Acta Neuropathol. 2014. doi: 10.1007/s00401-014-1355-2
114. Kilic E, Reitmeir R, Kilic, et al. HMG-CoA reductase inhibition promotes neurological recovery, perilesional tissue remodeling and contralesional pyramidal tract plasticity after focal cerebral ischemia. Front Cell Neurosci. 2014.
115. Hermann DM, Lehmann N, Gronewold J, et al. Thoracic aortic calcification is associated with incident stroke in the general population in addition to established risk factors. Eur Heart J Cardiovasc Imag. 2014.
116. Bacigaluppi M, Russo GL, Peruzzotti-Jametti L, et al. Neural stem cell transplantation promotes post-ischemic recovery through the glutamate transporter GLT1. J Clin Invest. 2014.

REVIEW ARTICLES

1. Hermann DM, Hossmann KA. Neurological effects of microwave exposure related to mobile communication. J. Neurol. Sci. 1997; 152: 1-14. doi: http://dx.doi.org/10.1016/S0022-510X(97)00140-8
2. Hermann DM, Bassetti C. Cerebral circulation and sleep. Sleep Med. Rev. 2002; 6: 425-427.
3. Hossmann KA, Hermann DM. Effects of electromagnetic radiation of mobile phones on the central nervous system. Bioelectromagnetics. 2003; 24: 49-62. doi: 10.1002/bem.10068
4. Hermann DM, Bassetti C. Sleep-disordered breathing and stroke. Curr. Opin. Neurol. 2003; 16: 87-90.
5. Hermann DM, Bassetti C. Sleep apnea and other sleep disorders in stroke. Curr. Treatm. Opt. Neurol. 2003; 5: 241-249.
6. Hermann DM, Siccoli M, Bassetti C. Sleep-wake disorders and stroke. Swiss Arch. Neurol. Psychiatr. 2003; 154: 369-374.
7. Kilic E, Hermann DM. TAT fusion proteins against ischemic stroke: Current status and future perspectives. Frontiers Biosci. 2006; 11: 1716-1721.
8. Grimm C, Hermann DM, Bogdanova A, et al. Neuroprotection by hypoxic preconditioning: HIF-1 and erythropoietin protect from retinal degeneration. Sem. Cell Dev. Biol. 2005; 16: 531-538.
9. Bassetti CL, Hermann DM. Foramen ovale closure: Feasible, but usually not necessary. Swiss Arch. Neurol. Psychiatr. 2006; 157: 180-183.
10. Hermann DM, Kilic E, Spudich A, Krämer SD, Wunderli H, Bassetti CL. Role of drug efflux carriers in the healthy and diseased brain. Ann. Neurol. 2006; 60: 489-498. doi: 10.1002/ana.21012
11. Hermann DM, Bassetti CL. Implications of ATP binding cassette transporters for brain pharmacotherapies. Trends Pharmacol. Sci. 2007; 28: 128-134.
12. Bacigaluppi M, Pluchino S, Kilic E, Martino G, Hermann DM. Neural precursor cells in the treatment of ischemic stroke. J. Neurol. Sci. 2007; 265: 73-77.
13. Siekierka-Kleiser EM, Eng K, Bassetti C, et al. New technologies and concepts for rehabilitation in the acute phase of stroke: A collaborative matrix. Neurodegen. Dis. 2007; 4: 57-69.
14. Hermann DM. Biodistribution processes as underestimated confounders in translational stroke research. Curr. Med. Chem. 2007; 14: 3179-3184.
15. Hermann DM, Matter CM. Tissue-plasminogen activator-induced reperfusion injury after stroke revisited. Circulation. 2007; 116: 363-365. doi: 10.1161/CIRCULATIONAHA.107.712380
16. Hermann DM, Bassetti C. Neuroprotection in the SAINT-II aftermath. Ann. Neurol. 2007; 62: 677-678. doi: 10.1002/ana.21210
17. Bacigaluppi M, Hermann DM. New targets of neuroprotection in ischemic stroke. Scientific World Jounal. 2008; 8: 698-712. doi: 10.1100/tsw.2008.94
18. Hermann DM. Future perspectives for brain pharmacotherapies: implications of drug transport processes at the blood-brain barrier. Ther. Adv. Neurol. Dis. 2008; 1: 167-181. doi: 10.1177/1756285608097775
19. Ennen JC, Mueller B, Bibl M, et al. Influence of multimodal physical activity on cognition and life skills in sooner Alzheimer s dementia SPORTS & KOG. Gerontopsychologie. 2008; 21: 163-169.
20. Hermann DM, Kilic E. Therapeutic potential and possible risk of pleiotropic growth factors in ischemic stroke. Stroke. 2008; 39: e182. doi: 10.1161/STROKEAHA.108.532374
21. Hermann DM. Blur in the projectability: The stroke numbers by half the 205th Dt. Medical Journal. 2008; 105: 844.
22. Hermann DM. Enhancing erythropoietin delivery to the ischemic brain. Scientific World Journal. 2009; 9: 967-969. doi: 10.1100/tsw.2009.104
23. Zechariah A, Hermann DM. Implications of vascular endothelial growth factor for postischemic neurovascular remodelling. J. Cereb. Blood Flow Metab. 2009; 29: 1620-1643. doi: 10.1038/jcbfm.2009.100
24. Hermann DM, Bassetti C. Sleep-related breathing and sleep-wake disturbances in ischemic stroke. Neurology. 2009; 73: 1313-1322. doi: 10.1212/WNL.0b013e3181bd137c
25. Bacigaluppi M, Comi G, Hermann DM. Animal models of ischemic stroke – Part 1: Models for risk factors. Open Neurology Journal. 2010; 4: 26-33.
26. Bacigaluppi M, Comi G, Hermann DM. Animal models of ischemic stroke – Part 2: Models of cerebral ischemia. Open Neurology Journal. 2010; 4: 34-38.
27. Hermann DM. Nonhematopoietic variants of erythropoietin in ischemic stroke: need for step-wise proof-of-concept studies. Scientific World Journal. 2010; 10: 2285-2287. doi: 10.1100/tsw.2010.226
28. Hermann DM. Neuroprotective und neurorestoration: Ready for translation to clinics? Swiss Arch. Neurol. Psychiatry. 2010; 161: 274-275.
29. Hermann DM. Neues zur Alzheimer-Demenz. Akt. Neurol. 2010; 37: 274-278.
30. Doeppner TR, Hermann DM. Free radical scavengers and spin traps – therapeutic implications for ischemic stroke. Best Pract. Res. Clin. Anaesth. 2010; 24: 511-520. doi: 10.1016/j.bpa.2010.10.003
31. Doeppner TR, Hermann DM. Mesenchymal stem cells in the treatment of ischemic stroke: progress and possibilities. Stem Cells Clon. 2010 3: 157-163. doi: http://dx.doi.org/10.2147/SCCAA.S7820
32. Hermann DM, Van Hook MA. Bringing drugs into the brain and keeping them there. Sci. Signal. 2010; 3142: 18.
33. ElAli A, Hermann DM. ATP-binding cassette transporters and their roles in protecting the brain. Neuroscientist. 2011; 17: 423-436. doi: 10.1177/1073858410391270.
34. Bassetti CL, Hermann DM. Sleep and stroke. Hand b. Clin. Neurol. 2011; 99: 1051-1072.
35. Hermann DM, Patak P. Bringing drugs into the brain and keeping them there Editorial. In: Hermann DM, Patak P, eds. Curr. Pharm. Dis. 2011; 17: 2787-2792.
36. Patak P, Hermann DM. ATP-binding cassette transporters at the blood-brain barrier in ischaemic stroke. Special issue: Bringing drugs into the brain and keeping them there. In: Hermann DM, Patak P, eds. Curr. Pharm. Dis. 2011; 17: 2748-2749.
37. Hermann DM, Chopp M. Promoting brain plasticity and remodeling for stroke recovery: Therapeutic potential, caveats and consequences for clinical translation. Lancet Neurol. 2012; 11, 369-380. doi: 10.1016/S1474-4422(12)70039-X
38. Ma Y, Zechariah A, Qu Y, Hermann DM. Effects of vascular endothelial growth factor in ischemic stroke. J. Neurosci. Res. 2012; 90: 1873-1882. doi: 10.1002/jnr.23088
39. Hermann DM, ElAli A. The abluminal endothelial membrane in neurovascular remodeling in health and disease. Sci. Signal. 2012; 5. doi: 10.1126/scisignal.2002886
40 Hermann DM, Grotz W. Cognitive impairment in chronic kidney disease. nephrologist. 2013; 8: 323-326.
41. Hermann DM, Nagel E. The dementia patient in hospital Zeitschrift medicine. ethics, law. 2013; 2: 36-41.
42. Hermann DM, Buga AM, Popa-Wagner A. Enabling brain plasticity and neurological recovery in the ischemic brain: effect of age and vascular risk factors as confounders. Rom J Morphol Embryol. 2013; 54: 3-6.
43. Hermann DM. Challenging current views on apolipoprotein-E s role as stroke predictor. Eur J Neurol. 2014; 21: 1051-1052. doi: 10.1111/ene.12377
44. Hermann DM, Buga AM, Popa-Wagner A. Neurovascular remodeling in the aged ischemic brain. J Neural Transm. 2013. doi: 10.1007/s00702-013-1148-0
45. Hermann DM, Kribben A, Bruck H. Cognitive impairment in chronic kidney disease: Neuroimaging findings, risk factors and consequences for patient care. J Neural Transm. 2014; 121: 627-632. doi: 10.1007/s00702-014-1160-z
46. Seidel UK, Gronewold J, Kribben MA, Bruck H, Hermann DM. Response to: Cognitive function over time in patients on chronic hemodialysis. Kidney Int. 2014; 85: 713.
47. Hermann DM. Alzheimer dementia: why therapy comes too late.MMW Fortschr Med. 2014; 1562: 36.
48. Hermann DM. Vitamin E delays the progression of Alzheimer s also only slightly. MMW Fortschr Med. 2014; 15611: 36.
49. Hermann DM, Muck S, Nehen HG. Supporting dementia patients in hospital environments: health-related risks, needs and dedicated structures for patient care. Eur J Neurol. 2014. doi: 10.1111/ene.12530
50. Nehen HG, Hermann DM. Supporting dementia patients and their caregivers in daily life challenges: review of physical, cognitive and psychosocial intervention studies. Eur J Neurol. 2014. doi: 10.1111/ene.12535
51. Hoyo-Becerra C, Schlaak JF, Hermann DM. Insights from interferon-α-related depression for the pathogenesis of depression associated with inflammation. Brain Behav Immun. 2014; 42C: 222-231. doi: 10.1016/j.bbi.2014.06.200
52. Hermann DM, Chopp M. Promoting neurological recovery in the post-acute stroke phase: benefits and challenges. Eur Neurol. 2014; 72: 317-325. doi: 10.1159/000365171
53. Hermann DM, Peruzzotti-Jametti L, Schlechter J, Bernstock JD, Doeppner TR, Pluchino S. Neural precursor cells in the ischemic brain – integration, cellular crosstalk, and consequences for stroke recovery. Front Cell Neurosci. 2014; 8: 291.
54. Popa-Wagner A, Buga AM, Doeppner TR, Hermann DM. Stem cell therapies in preclinical models of stroke associated with aging. Front Cell Neurosci. 2014; 8: 347.
55. Doeppner TR, Hermann DM. Stem cell-based treatments against stroke: observations from human proof-of-concept studies and considerations regarding clinical applicability. Front Cell Neurosci. 2014; 8: 357.

BOOK CHAPTERS

1. Hermann DM, Hincke P, Luppi PH, Jouvet M. Afferents to the nucleus raphe magnus demonstrated by iontophoretic application of unconjugated cholera toxin b in rats and guinea-pigs. Integrative and Cellular Aspects of Autonomic Functions: Temperature- and Osmoregulation. In: Pleschka K, Gerstberger R, eds. Verlag John Libbey, Strasbourg. 1994; 243-252.
2. Hermann DM, Hincke P, Luppi PH, Jouvet M. Functional neuroanatomical considerations on afferent and efferent connections of the nucleus raphe magnus. Thermal Balance in Health and Disease. In: Zeisberger E, Schönbaum E, Lomax P, eds. Birkhäuser Verlag, Basel, Boston, Berlin. 1994; 79-84.
3. Pollmächer T, Mullington J, Hinze-Selch D, Orth A, Hermann DM, Holsboer F. The influence of experimental stimulation of the primary host response to human sleep. Contributions to. Congress of the Society for Biological Psychiatry. 1995.
4. Hermann DM, Mullington J, Korth C, Pollmächer T. Morning endotoxin leads to foothill before suppression of NREM sleep Direction in G-CSF-pretreated subjects Sleep Research. Mnchener medical publishing MMW. 1994; 129-131.
5. Hermann DM. Afferente und efferente Raphe magnus and projections of the nuclei under pallidus Bercksichtigung thermal adaptation. Inaugural dissertation leading to a doctoral degree in medicine, Faculty of Medicine, University of Giessen. 1995.
6. Hermann DM, Mies G, Hossmann KA. Metabolic disturbances and gene responses following cortical injury in rats: Relationship to spreading depression. Maturation Phenomenon in Cerebral Ischemia: Defensive Mechanisms versus Apoptosis. In: Fieschi C, Ito U, Orzi F, Kuroiwa T, Klatzo I. 1999; 183-192.
7. Hossmann KA, Hermann DM. Health aspects of mobile communication: Risks to the central nervous system. Electricity and Magnetism in Biology and Medicine. In: Bersani F, Kluwer Academic / Plenum Publishers. 1999; 37-41.
8. Mies G, Trapp T, Kilic E, Oláh L, et al. Relationship between DNA fragmentation, energy state, and protein synthesis after transient focal cerebral ischemia in mice. Maturation Phenomenon in Cerebral Ischemia IV, Defensive mechanisms versus apoptosis, recovery, and protection in cerebral ischemia. Bazan N, Ito U, Kuroiwa T. Springer-Verlag, Berlin, Heidelberg. 2001; 85-92.
9. Hermann DM. Secondary damage development and neuroprotective therapy in focal ischemia and traumatic Kortexläsion. Habilitation Thesis Faculty of Medicine, Eberhard-Karls-University Tbingen. 2002.
10. Hermann DM, Bassetti C. Transient ischemic attack and ischemic stroke Cardix 2005. In: Lscher TF, Schwegler PR. Zrich AG. 2005; 71-77.
11. Hermann DM, Bassetti C. Sleep disorders after stroke In: Recovery after stroke. Bogousslavsky J, Dobkin B, Barnes M. Cambridge University Press, Cambridge. 2005; 580-603.
12. Hermann DM, Bassetti C. Transient ischemic attack and ischemic stroke Cardix of 2007. In: Lscher TF, Schwegler PR, Zrich AG, eds. 2007; 83-89.
13. Hermann DM. Biodistribution processes: Underestimated confounders in neuroprotective drug development. Brain Hypoxia Ischemia Research Progress. In: Columbus F, Novapublishers, New York. 2008.
14. Hermann DM, Bassetti C. Transient ischemic attack and ischemic stroke Cardix of 2009. In: Lscher TF, Schwegler PR, Zrich AG, eds. 2009.
15. Hermann DM, Bassetti C. Transient ischemic attack and ischemic stroke. Cardix 2009 engl. In: Lscher TF, Schwegler PR, Zrich AG, eds. 2009.
16. Hermann DM, Bassetti C. Sleep disorders and stroke: Causes and consequences In: Sleep Disorders in Neurological Disease: a Practical Approach. . Overeem S,Reading P, eds. Wiley-Blackwell, New York. 2010.
17. Patak P, Hermann DM. From bedside to bench: How the clinical reality should instruct the modeling of stroke. Rodent Models of Stroke. In: Dirnagl U. Humana Press, Springer Verlag, New York. 2010.
18. Hermann DM. Anatomy and physiology of the cerebral vascular system. Vascular Neurology. In: Hermann DM, Steiner T, Diener HC, eds. Thieme-Verlag, Stuttgart, 2010, 1 : 3-7.
19. Reitmeir R, Hermann DM. Pathophysiology of vascular-neurological diseases. In: Vascular Neurology. In: Hermann DM, Steiner T, Diener HC, eds. Thieme-Verlag, Stuttgart, 2010; 8-13.
20. Bassetti CL, Hermann DM. Clinical syndromes in vascular neurology. Vascular Neurology. In: Hermann DM, Steiner T, Diener HC, eds. Thieme-Verlag, Stuttgart. 1: 2010; 14-25.
21. Bacigaluppi M, Hermann DM. Hypercholesterolemia, hyperhomocysteinemia and atherosclerosis. Vascular Neurology. In: Hermann DM, Steiner T, Diener HC, eds. Thieme-Verlag, Stuttgart. 2010; 1: 36-44.
22. Hermann DM, Teschler H, Bassetti C. Associated sleep disordered breathing. Vascular Neurology. In: Hermann DM, Steiner T, Diener HC, eds. Thieme-Verlag, Stuttgart. 2010; 1: 74-76.
23. Hermann DM, Patak P. Smoking and substance abuse. Vascular Neurology. In: Hermann DM, Steiner T, Diener HC, eds. Thieme-Verlag, Stuttgart. 2010; 1: 88-90.
24. Hermann DM, Patak P. Oral contraceptives and hormone replacement therapy. Vascular Neurology. In: Hermann DM, Steiner T, Diener HC, eds. Thieme-Verlag, Stuttgart. 2010; 91-92.
25. Hermann DM. Challenges pharmacological therapies in vascular neurology. Vascular Neurology. In: Hermann DM, Steiner T, Diener HC, eds. Thieme-Verlag, Stuttgart. 2010; 1: 121-123.
26. Bacigaluppi M, Hermann DM. Cholesterol reduction and stabilization of vascular function. Vascular Neurology. In: Hermann DM, Steiner T, Diener HC, eds. Thieme-Verlag, Stuttgart. 2010; 1: 149-155.
27. Hermann DM, Bassetti CL. Treatment of sleep-associated breathing disorders. Vascular Neurology. In: Hermann DM, Steiner T, Diener HC, eds. Thieme-Verlag, Stuttgart. 2010; 171-173.
28. Hermann DM, Bassetti C. Ischemic stroke: epidemiology, presentation and classification. Vascular Neurology. In: Hermann DM, Steiner T, Diener HC, eds. Thieme-Verlag, Stuttgart. 2010; 191-194.
29. Todica O, Wiltfang J, Hermann DM. Vascular dementia. Vascular Neurology. In: Hermann DM, Steiner T, Diener HC, eds. Thieme-Verlag, Stuttgart. 2010; 269-276.
30. Patak P, Kastrup O, Hermann DMRare stroke syndromes. Vascular Neurology. In: Hermann DM, Steiner T, Diener HC, eds. Thieme-Verlag, Stuttgart. 2010; 277-282.
31. Bassetti CL, Hermann DM. Pitfalls in clinical diagnostics. Vascular Neurology. In: Hermann DM, Steiner T, Diener HC, eds. Thieme-Verlag, Stuttgart. 2010; 321-324.
32. Hermann DM, Steiner T, Diener HC. Perspectives in Vascular Neurology Vascular Neurology. In: Hermann DM, Steiner T, Diener HC, eds. Thieme-Verlag, Stuttgart. 2010; 339-341.
33. Hermann DM, Rosenkranz M. Transient global amnesia. Therapy and outcome of neurological diseases. In: Brandt T, Diener HC, Gerloff C, eds. Kohlhammer-Verlag, Stuttgart. 2012; 6.
34. Remi J, Hermann DM, Hummel F, Noachtar S. sleep. Therapy and outcome of neurological diseases. In: Brandt T, Diener HC, Gerloff C, eds. Kohlhammer-Verlag, Stuttgart. 2012.
35. Kastrup O, Hermann DM, Diener HC. Side effects of drug therapies in neurology. Therapy and outcome of neurological diseases. In: Brandt T, Diener HC, Gerloff C, eds. Kohlhammer-Verlag, Stuttgart. 2012.

PUBLICATION OF A TEXTBOOK

1. Hermann DM, Steiner T, Diener HC. Vaskuläre Neurologie, 1. Auflage. Thieme-Verlag, Stuttgart. 2010; 354.