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Article in press
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A Case Report on Vogt-Koyanagi-Harada Disease Seen at a Tertiary Hospital in the Philippines
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Do You Still Use Topical Antibiotics after Intravitreal Injections?
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Abstract [+]
Nowadays intravitreal drug injection is the most frequent treatment for retinal diseases. Despite widely use endophthalmitis is already most feared complication of every intravitreal injection in each patient. In clinical setting topical antibiotics have been widely used as a precaution to prevent endophthalmitis however recent published evidence showed it to be unnecessary. Furthermore repeated use of topical antibiotics might give rise to antibiotic resistance in conjunctival flora and thus more aggressive endophthalmitis. Strict asepsis has been awarded as the main rule for endophthalmitis prophylaxis intravitreal injection.
Keywords
Intravitreal injection; Steroid; Anti-vascular endothelial growth factor (VEGF); Topical antibiotic; Enodphthalmitis; Antibiotic resistance.
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Complications Related to Implants Used in Anterior Bleb Forming Glaucoma Surgery: A Systematic Review of the Literature
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Abstract [+]
Purpose
To make an account of published implant-related complications (IRC) by a systematic review of the literature.
Methods
A systematic search of Pubmed and Scopus databases and Google Scholar engine was performed with selection criteria to detect papers on IRC. We excluded unrelated papers and reviewed selected ones. We considered papers that did not explicitly state about occurrence or not occurrence of IRC as non-IRC reporting. Main outcome measures were the number of papers reporting on complications, IRC, and types of IRC.
Results
After the search, selection, and addition, we studied 109 papers. Incidence of IRC was 4.5%, half required explantation. While 26 implant studies found IRCs (23%), 13 case reports on surgical complications, 8 (61.5%) of them reported IRC. Frequent complications were conjunctival erosion, blockage of the tube, migration to anterior chamber or damage to surrounding tissues.
Conclusion
Most papers did not report on IRC. Length or nature of studies may skew finding IRC. The incidence of IRC was 4.5%. Hard and sharp implants carry a greater risk of IRC and explantation.
Keywords
Implant-related complications (IRC); Glaucoma surgery; Anterior bleb forming.
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Editor-in-Chief
Adam J. Cohen, MD
2591 Compass Rd. Ste 115 Glenview, IL 60026, USA and Assistant Professor of Ophthalmology Section Director of Oculoplastic and Reconstructive Surgery Rush University School of Medicine Chicago, IL 60026, USA
Associate Editors
Hoai Viet Tran, FEBO
Medicine Practitioner Hôpital ophtalmique Jules-Gonin Lausanne, Switzerland
Syed Shoeb Ahmad, MBBS, MS, FAEH, FCLI
Ophthalmology Specialist Department of Ophthalmology Queen Elizabeth Hospital Kota Kinabalu, Malaysia
Xiaoyan Ding, PhD
Faculty Department of Vitreous-Retina Zhongshan Ophthalmic Center Sun Ya-Sen University Guangdong, China
Jennifer Kielczewski, PhD
Staff Scientist National Eye Institute National Institutes of Health Biological Imaging Core (BIC) 6 Center Drive Bldg. 6 Room 206B Bethesda, MD 20892-0606