Skip to content
  • Facebook
  • Twitter
  • linkedin
  • Instagram
Open Access Publisher of Medical and Social Science Journals
Openventio Publishers
  • Home
  • About us
    • Vision/Mission
    • Open Access
    • Editorial Assessment and Peer Review Process
  • Journals
  • Editorial Guidelines
    • For Authors
    • For Editors
    • For Reviewers
    • For Readers
    • For Librarians
  • Submit Manuscript
  • Contact Us
  • More
    • Advertisement
    • Reprints
    • Privacy Policy
    • FAQs

Volume 5

December, 2018-2019

Volume 5, Issue 1

[ Download PDF ]

Volume 4

January, 2017

Volume 4, Issue 1

[ Download PDF ]

December, 2017

Volume 4, Issue 2

[ Download PDF ]

Volume 3

May, 2016

Volume 3, Issue 1

[ Download PDF ]

September, 2016

Volume 3, Issue 2

[ Download PDF ]

Volume 2

October, 2015

Volume 2, Issue 3

[ Download PDF ]

June, 2015

Volume 2, Issue 2

[ Download PDF ]

March, 2015

Volume 2, Issue 1

[ Download PDF ]

February, 2016

Volume 2, Issue 4

[ Download PDF ]

Volume 1

December, 2014

Volume 1, Issue 1

[ Download PDF ]

Special Edition

May, 2017

Special Edition 1

[ Download PDF ]

December, 2017

Special Edition 2

[ Download PDF ]

×

Article in press

NOTE: The DOIs of the In-Press Articles will only function after the final publication of the articles and once they are uploaded to the Current Issues.
×

Current Issue

  • 2018, August

    editorial

    New Ideas on Limitations to VO2max: Five Major Determinants for VO2maxOpen Access

    Masahiro Kohzuki*
    DOI: http://dx.doi.org/10.17140/PRRMOJ-5-e010
    PDF398.63 KB 398.63 KB
    Full-Text (HTML)
    Full-Text (HTML)

  • 2019, December

    case report

    A Rare Case of Gemcitabine-Induced Pulmonary HypertensionOpen Access

    Janice Shen, Su Yun Chung, Elham Azimi-Nekoo, Jyothi Jose and Muhammad W. Saif*
    DOI: http://dx.doi.org/10.17140/PRRMOJ-5-139
    PDF405.55 KB 405.55 KB
    Full-Text (HTML)
    Full-Text (HTML)
    Abstract [+]

    Context

    Gemcitabine is the backbone of systemic treatment of locally advanced and metastatic intrahepatic cholangiocarcinoma. In recent literature, gemcitabine has been linked to various pulmonary side effects.

    Case Report

    We report a case of an 82-year-old male who developed acute pulmonary hypertension after receiving one cycle of gemcitabine for metastatic cholangiocarcinoma. His symptoms began with fatigue associated with shortness of breath and cough that worsened despite dose reduction. He developed new onset bilateral pulmonary effusions and an echocardiogram revealed findings consistent with pulmonary hypertension. A computed tomography (CT) angiogram was negative for pulmonary thromboembolism. Although he was promptly treated with diuretics and steroids, the patient could not tolerate any further therapy.

    Conclusion

    Gemcitabine-induced pulmonary hypertension is rare and can be challenging to diagnose, as it remains a diagnosis of exclusion. However, physicians should be vigilant of new pulmonary symptoms, as delayed treatment can cause significant patient morbidity and mortality.

    Keywords

    Cholangiocarcinoma; Gemcitabine; Pulmonary hypertension.

    Abbreviations

    CT: Computed Tomography; PE: Pulmonary Thromboembolism; GIPT: Gemcitabine-Induced Pulmonary Toxicity.


×

Previous Issue

  • 2017, March

    original research

    Significance of Combined Emphysema in Idiopathic Pulmonary Fibrosis and Serum Surfactant Protein-D as a Prognostic FactorOpen Access

    Keiki Yokoo, Masanori Shiratori*, Kimiyuki Ikeda, Yasuaki Umeda, Mitsuo Otsuka, Hirotaka Nishikiori, Hirofumi Chiba, Hiroyuki Koba and Hiroki Takahashi
    DOI: http://dx.doi.org/10.17140/PRRMOJ-4-135
    PDF522.20 KB 522.20 KB
    Full-Text (HTML)

  • 2017, March

    editorial

    Balloon Pulmonary Angioplasty (BPA) and Rehabilitation for Chronic Thromboembolic Pulmonary Hypertension (CTEPH)Open Access

    Masahiro Kohzuki*
    DOI: http://dx.doi.org/10.17140/PRRMOJ-4-e007
    PDF326.74 KB 326.74 KB
    Full-Text (HTML)

  • 2017, July

    case report

    Vitamin C Infusion for Gastric Acid Aspiration-Induced Acute Respiratory Distress Syndrome (ARDS)Open Access

    Christin Kim, Orlando Debesa, Patricia Nicolato, Bernard Fisher, Ramesh Natarajan and Alpha Alsbury Fowler, III*
    DOI: http://dx.doi.org/10.17140/PRRMOJ-4-136
    PDF2.00 MB 2.00 MB
    Full-Text (HTML)

  • 2017, September

    editorial

    The Importance of Rehabilitation before and after Lung TransplantationOpen Access

    Masahiro Kohzuki*, Yosuke Izoe and Taku Harada
    DOI: http://dx.doi.org/10.17140/PRRMOJ-4-e008
    PDF308.78 KB 308.78 KB
    Full-Text (HTML)

  • 2017, September

    editorial

    Paraneoplastic Syndrome: What should Pulmonologists know?Open Access

    Takeshi Saraya*
    DOI: http://dx.doi.org/10.17140/PRRMOJ-4-e009
    PDF694.51 KB 694.51 KB
    Full-Text (HTML)

  • 2017, September

    brief research

    Diagnosis of Pulmonary and Extra Pulmonary Tuberculosis: How Best is CBNAAT when Compared to Conventional Methods of TB Detection?Open Access

    Subhakar Kandi*, Vikasana Reddy and Sharath Burugina Nagaraja
    DOI: http://dx.doi.org/10.17140/PRRMOJ-4-137
    PDF347.38 KB 347.38 KB
    Full-Text (HTML)

  • 2017, December

    original research

    Refusal of Venous Thromboembolism Prophylaxis and Incidence of Thrombosis in Patients with Cystic FibrosisOpen Access

    Taryn S. Murray, Nicole L. Metzger*, Melissa M. Chesson and Seth D. Walker
    DOI: http://dx.doi.org/10.17140/PRRMOJ-4-138
    PDF429.79 KB 429.79 KB
    Full-Text (HTML)

    • Home
    • Authors Instructions
    • Submit Manuscript
    • Contact Us
    • Editorial Panel
    • Article in press
    • Current issue
    • Previous issue
    • Archive
    • Archive

    Connect with us



    Editor-in-Chief

    Masahiro Kohzuki, MD, PhD


    Associate Dean
    Professor and Chairman
    Department of Internal Medicine and Rehabilitation Science, Disability Sciences
    Tohoku University Graduate School of Medicine
    Chairman of the CentTohoku University Hospital
    Japaner of Rehabilitation Medicine

    Associate Editors

    Zhaolin Xu, MD, FRCPC, FCAP


    Professor, Dept. of Pathology, Dalhousie University
    Pulmonary Pathologist and Cytopathologist, QE II Health Sciences Centre
    Senior Scientist, Beatrice Hunter Cancer Research Institute
    5788 University Ave
    Halifax NS B3H 1V8, Canada

    Rasha Daabis, MD


    Associate Professor of Chest Diseases
    Faculty of Medicine
    Alexandria University
    Egypt

    Takeshi Saraya, MD, PhD


    Assistant Professor
    Department of Respiratory Medicine
    Kyorin University School of Medicine
    Mitaka City, Tokyo, Japan

    E-mail: sara@yd5.so-net.ne.jp

    Our editorial team


    Advertisement

    About Openventio

    Openventio Publishers is licensed under a Creative Commons Attribution 4.0 International License.
    based on the work at www.openventio.org

    Quick Links
    • Open Access
    • Submit Manuscript
    • Authors Instructions
    • Journals
    • Editorial Guidelines
    • Contact Us
    • Reprints
    • FAQs
    • Advertisement
    Find Us

    Suite#B013, Nexus Business Center
    Block-B, Level 2, Road no. 3
    Film Nagar, Hyderabad
    Telangana State, India

    Openventio Publishers
    • Facebook
    • Twitter
    • linkedin
    • Instagram
    © 2014 - 2022 Openventio Publishers. All Rights Reserved.
    • Open Access
    • Submit Manuscript
    • Authors Instructions
    • Journals
    • Editorial Guidelines
    • Contact Us
    • Reprints
    • FAQs
    • Advertisement