Article in press
Current Issue
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2019, February
editorial
Review on Artificial Intelligence and Applications in Healthcare
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2019, February
original research
Reirradiation of Recurrent Tumors in Central Nervous System in Children and Adolescents
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2019, March
mini review
Vision in the Hearing-Impaired: Enhanced or Deprived?
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2019, June
brief report
The Praxitype: An Improved Interpretation of Genotype-Phenotype Variation
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Abstract [+]
There is a need for an understanding of the genomic reality that realizes a connector between the genotype and the phenotype by addressing HOW the genotype actually manifests as the phenotype, as a function of the locus or the allele, mutated, variant or wildtype. That understanding is encompassed by the notion of the PRAXITYPE, which assembles and presents the available answers to the HOW!
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2019, August
review
Stroke Prevention: Extra-Cranial Carotid Artery Therapy
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501.11 KB
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Abstract [+]
A patient-centered approach is reasonable in candidates for carotid revascularization. The patient and their physician should discuss the available treatment options, including revascularization (either carotid artery stenting (CAS) or carotid endarterectomy (CEA)) with their physician. There remains uncertainty regarding the value proposition for revascularization (either CEA or CAS) in asymptomatic patients as a strategy to prevent stroke. Investigation continues into characterizing high-risk carotid plaque subsets, but until that data is available, physicians and patients should continue to strive to achieve the best outcomes with the information that is currently available. The other consideration in asymptomatic patients is that there is a cumulative benefit to revascularization that is dependent on life expectancy. However, the magnitude of the benefit of revascularization, over the longer term in the setting of multifactorial medical therapy, including statins, is not known.
Keywords
Carotid endarterectomy; Carotid stent; Angioplasty; Embolic protection devices.
Previous Issue
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2018, August
editorial
Pulvinar Complex: Relay Center or Something More?
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328.27 KB
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2018, December
editorial