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Volume 5

December, 2021

Volume 5, Issue 1

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Volume 4

December, 2020

Volume 4, Issue 1

[ Download PDF ]

Volume 3

December, 2019

Volume 3, Issue 1

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Volume 2

December, 2018

Volume 2, Issue 1

[ Download PDF ]

Volume 1

April, 2017

Volume 1, Issue 1

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Article in press

NOTE: The DOIs of the In-Press Articles will only function after the final publication of the articles and once they are uploaded to the Current Issues.
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Current Issue

  • 2021, July

    case report

    Acute Liver Injury after Three Doses of NitrofurantoinOpen Access

    Thejeswi Pujar*, Joy Lee and Siegfried Yu
    DOI: http://dx.doi.org/10.17140/IMOJ-5-115
    PDF273.07 KB 273.07 KB
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    Abstract [+]

    A 56-year-old lady presented to the hospital with 2-day history of flu like symptoms. These had begun within a few hours after starting Nitrofurantoin for urinary tract infection that was prescribed by her primary care doctor. Blood tests upon admission revealed elevated aminotransferase levels with normal bilirubin levels. The medication was stopped, and other causes of hepatitis were investigated. Nitrofurantoin induced idiosyncratic drug-induced liver injury (IDILI) was confirmed by excluding all other causes. Patient’s symptoms and liver enzymes improved the next day and she was discharged. A follow-up on the laboratory’s nine-days later revealed liver enzymes almost back to normal.
    Keywords
    Nitrofurantoin; Urinary tract infection; Idiosyncratic drug induced liver injury; Acute reversible hepatotoxicity; Flu-like illness; Elevated transaminases.


  • 2021, September

    case illustration

    Juvenile Gangrenous Vasculitis of the ScrotumOpen Access

    Cameron S. Nichols* and Fnu Nutan
    DOI: http://dx.doi.org/10.17140/IMOJ-5-116
    PDF246.21 KB 246.21 KB
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  • 2021, December

    review

    Coronavirus Disease-2019 Vaccines and the Vaccination Challenges in India: A ReviewOpen Access

    Imran R. Rangraze*, Shehla S. Khan and Yakub Sayyad
    DOI: http://dx.doi.org/10.17140/IMOJ-5-117
    PDF448.50 KB 448.50 KB
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    Abstract [+]

    The severe acute respiratory syndrome corona virus-2 (SARS-CoV-2) designated as novel coronavirus is a cause of highly infectious disease referred to as coronavirus disease-2019 (COVID-19). The global pandemic that affected millions of people worldwide has claimed many lives and brought about catastrophe in low-income countries. The high mortality and rapid spread of the infection have brought about an urgent need for a safe and effective vaccine to control the pandemic. In this perspective, it becomes essential to understand the structure, mode of transmission, and virulence of SARS-Cov-2. In this article, an emphasis is made on understanding the infection pathogenesis and the host defense mechanisms against the infection to break the chain of transmission. Furthermore, we have tried to summarize the development and characteristics of different types of COVID-19 vaccines. In addition to this, we have highlighted the challenges of the public health system in the procurement and delivery of
    the vaccine to the community and especially to the most vulnerable society. It becomes the main priority to find support financially and make the public health system ready to imbibe the importance of vaccination through meticulous strategies so that vaccine reaches out to the community.
    Keywords
    SARS-CoV-2; COVID-19; Vaccine; COVID-19 treatment.


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Previous Issue

  • 2020, April

    case report

    Pseudo Metabolic Acidosis in the Setting of Hypertriglyceridemia: A Case ReportOpen Access

    Atul Bali* and Roopa Naik
    DOI: http://dx.doi.org/10.17140/IMOJ-4-111
    PDF213.87 KB 213.87 KB
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    Abstract [+]

    Low serum bicarbonate, with or without an elevated anion gap, can indicate metabolic acidosis. High anion gap metabolic acidosis is due to the unmeasured anions. Hypertriglyceridemia can also be associated with spuriously low serum bicarbonate levels due to lab interference. We present a 44-year-old woman who presented with anion gap metabolic acidosis in the presence of severe hypertriglyceridemia.

    Keywords

    Hypertriglyceridemia; Acid-base disorders; Low serum bicarbonate; Metabolic acidosis.


  • 2020, June

    short communication

    Proteinuria: A Guide to Diagnosis and AssessmentOpen Access

    Sasha-Kay D’Aguilar and Amith Skandhan*
    DOI: http://dx.doi.org/10.17140/IMOJ-4-112
    PDF397.46 KB 397.46 KB
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    Abstract [+]

    Proteinuria is a common incidental finding that physicians face in the inpatient and outpatient setting. Proteinuria may represent a benign pathology in asymptomatic patients, or it can be a sign of significant renal or systemic disease. The latter is usually associated with persistent proteinuria or other clinical findings such as renal failure. This article will focus on the mechanisms, causes and diagnostic approach of proteinuria. Proteinuria is a common incidental finding that physicians face in the inpatient and outpatient setting. Proteinuria may represent a benign pathology in asymptomatic patients, or it can be a sign of significant renal or systemic disease. The latter is usually associated with persistent proteinuria or other clinical findings such as renal failure. This article will focus on the mechanisms, causes and diagnostic approach of proteinuria.
    Keywords
    Proteinuria; Glomerular; Tubular; Nephritic; Nephrotic.


  • 2020, September

    mini review

    Sodium-Glucose Cotransporter-2 Inhibitors and Cardiovascular Disease: Lessons and the FutureOpen Access

    Abdulhalim J. A. Kinsara*, Atif Al Qubbany and Wail Alkashkari
    DOI: http://dx.doi.org/10.17140/IMOJ-4-113
    PDF274.70 KB 274.70 KB
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    Abstract [+]

    Diabetes mellitus (DM), an epidemic non-communicable disease, is associated with macro- and micro-vascular complications which may result in sudden cardiac death at a young age. Sodium-glucose cotransporter-2 inhibitors (SGLT2-I) emerged as a new therapeutic option for managing DM with cardiovascular complications as well as diabetic patients with multiple risk factors. Three drugs in this class significantly reduced cardiovascular mortality and heart failure events, in both type 2 diabetes mellitus and non-diabetic patients with a reduced ejection fraction, to prevent heart failure related hospitalisation. Evidence of kidney protection was another major advantage provided in more than one study. We reviewed recent SGLT2-I related literature and discuss the benefits beyond the cardiac system.
    Keywords
    Diabetes mellitus (DM); Cardiovascular disease; Sodium-glucose cotransporter-2 inhibitors (SGLT2-I); Renal protection.


  • 2020, September

    case report

    Leg Ulcer in Patient with Sickle Cell Disease on HydroxyureaOpen Access

    Jaya Manjunath and Fnu Nutan*
    DOI: http://dx.doi.org/10.17140/IMOJ-4-114
    PDF310.85 KB 310.85 KB
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    Abstract [+]

    Leg ulcers are a painful side-effect commonly seen in patients with long-term use of hydroxyurea. We describe an ulcer in a patient with sickle cell disease (SCD) with an 8-year history of hydroxyurea use. Wound care team used cadexomer-iodine topical
    and collagenase to aid in healing. There are limited options for the treatment of these ulcers beside the cessation of hydroxyurea, a very effective drug in reducing painful sickle cell episodes. It is imperative to be aware of this complication to prevent expensive tests and further work up. Future study into alternative treatment of hydroxyurea-induced leg ulcers for sickle cell patients is necessary.
    Keywords
    Leg Ulcer; Sickle cell disease (SCD); Hydroxyurea.


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    Editor-in-Chief

    Vladislav Zimin, MD, PhD


    Interventional Cardiologist Trained Overseas
    Research Fellow at the University Hospitals Cleveland Medical Center
    10900 Euclid Avenue
    Cleveland, Ohio 44106, USA

    Associate Editors

    Arnon Blum, MD


    Director of Medicine
    Professor
    Department of Medicine
    Baruch Padeh Poria Medical Center affiliated to the Faculty of Medicine
    Bar-Ilan University
    Ramat Gan, 5290002, Israel

    Alessandro Anselmo, MD, PhD


    Specialist in General Surgery
    Aggregate Professor of Surgery
    Tor Vergata University
    Rome, Italy

    Our editorial team


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