Internal Medicine - Open Journal (IMOJ)
Recently Published Issues
Happy Authors
"I was impressed with the speed of the process of review. The reviewers were excellent in their comments and improved the quality of the article. The entire experience was phenomenal."
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Recently Published Articles
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Coronavirus Disease-2019 Vaccines and the Vaccination Challenges in India: A Review
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448.50 KB Full-Text (HTML)
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Sodium-Glucose Cotransporter-2 Inhibitors and Cardiovascular Disease: Lessons and the Future
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274.70 KB Full-Text (HTML)
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Pseudo Metabolic Acidosis in the Setting of Hypertriglyceridemia: A Case Report
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213.87 KB Full-Text (HTML)
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Morbidity and Mortality Associated with Development of Hypogammaglobulinemia after Rituximab
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394.56 KB Full-Text (HTML)
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Efficacy and Safety of Clarithromycin, Lenalidomide and Dexamethasone (Bird) Therapy for Japanese Patients with Relapsed or Refractory Multiple Myeloma
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415.88 KB Full-Text (HTML)
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Levamisole in Medicine
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273.79 KB Full-Text (HTML)
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Efficacy and Safety of Lenalidomide Prednisolone Combination Treatment for Japanese Elderly Multiple Myeloma Patients
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414.52 KB Full-Text (HTML)
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Anarchic Deposits: The Intersection of Calciphylaxis and Hemochromatosis, A Case Report
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691.13 KB Full-Text (HTML)
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Successful Third Hematopoietic Stem Cell Transplantation for Blast Crisis of Chronic Myeloid Leukemia After Two Times of Graft Failure
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1,018.52 KB Full-Text (HTML)
About the Journal
Internal Medicine – Open Journal (IMOJ) is an online open access journal that serves as a one-stop reference for Internal Medicine or General Medicine.
Internal Medicine is a branch of medicine that deals with prevention, diagnosis, and treatment of adult diseases.
Openventio aims to act as a complete reference point for all Internal Medicine professionals and students across the world.
Aims and Scope
Internal Medicine – Open Journal is dedicated for promoting patient care, research, education in primary care, general medicine, and hospital medicine.
IMOJ covers a wide array of subjects as given below
- Immunization
- Obesity and weight management
- Vascular biology
- Internal medicine
- Menopause
- Cardiovascular disease
- Stem cell research
- Translational medicine
Openventio wants to encourage participation of ever growing medical community to ensure data gets recorded and passed on to new practitioners in the field of medicine.
Submissions for this Journal are accepted from all practitioners and students of Internal medicine, from experts in the field to novices who are just starting to learn and understand Internal medicine.
The contributors of IMOJ includes doctors, nurses, research assistants, local community practitioners, manufacturers and students of various universities and general communities from different parts of the world.
The journal welcomes all types of articles such as original research, review, case-report, mini-review, editorial, short-communication, book review, opinion, commentary, letter to the editor, conference proceedings, technical report, errata, illustrations, etc. This journal accepts all type of manuscripts providing knowledge on various aspects of internal medicine.
We are open to receive comments or any corrections from any potential scientists to improve the quality of our Journal. Any comments /feedback from any potential scientists to improve the journal quality would be appreciated.
Current Issue
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Acute Liver Injury after Three Doses of Nitrofurantoin
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273.07 KB Full-Text (HTML)
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Abstract [+]
A 56-year-old lady presented to the hospital with 2-day history of flu like symptoms. These had begun within a few hours after starting Nitrofurantoin for urinary tract infection that was prescribed by her primary care doctor. Blood tests upon admission revealed elevated aminotransferase levels with normal bilirubin levels. The medication was stopped, and other causes of hepatitis were investigated. Nitrofurantoin induced idiosyncratic drug-induced liver injury (IDILI) was confirmed by excluding all other causes. Patient’s symptoms and liver enzymes improved the next day and she was discharged. A follow-up on the laboratory’s nine-days later revealed liver enzymes almost back to normal.
Keywords
Nitrofurantoin; Urinary tract infection; Idiosyncratic drug induced liver injury; Acute reversible hepatotoxicity; Flu-like illness; Elevated transaminases.
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Coronavirus Disease-2019 Vaccines and the Vaccination Challenges in India: A Review
PDF
448.50 KB Full-Text (HTML)
Full-Text (HTML)
Abstract [+]
The severe acute respiratory syndrome corona virus-2 (SARS-CoV-2) designated as novel coronavirus is a cause of highly infectious disease referred to as coronavirus disease-2019 (COVID-19). The global pandemic that affected millions of people worldwide has claimed many lives and brought about catastrophe in low-income countries. The high mortality and rapid spread of the infection have brought about an urgent need for a safe and effective vaccine to control the pandemic. In this perspective, it becomes essential to understand the structure, mode of transmission, and virulence of SARS-Cov-2. In this article, an emphasis is made on understanding the infection pathogenesis and the host defense mechanisms against the infection to break the chain of transmission. Furthermore, we have tried to summarize the development and characteristics of different types of COVID-19 vaccines. In addition to this, we have highlighted the challenges of the public health system in the procurement and delivery of
the vaccine to the community and especially to the most vulnerable society. It becomes the main priority to find support financially and make the public health system ready to imbibe the importance of vaccination through meticulous strategies so that vaccine reaches out to the community.
Keywords
SARS-CoV-2; COVID-19; Vaccine; COVID-19 treatment.
Previous Issue
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Pseudo Metabolic Acidosis in the Setting of Hypertriglyceridemia: A Case Report
PDF
213.87 KB Full-Text (HTML)
Abstract [+]
Low serum bicarbonate, with or without an elevated anion gap, can indicate metabolic acidosis. High anion gap metabolic acidosis is due to the unmeasured anions. Hypertriglyceridemia can also be associated with spuriously low serum bicarbonate levels due to lab interference. We present a 44-year-old woman who presented with anion gap metabolic acidosis in the presence of severe hypertriglyceridemia.
Keywords
Hypertriglyceridemia; Acid-base disorders; Low serum bicarbonate; Metabolic acidosis.
Proteinuria: A Guide to Diagnosis and Assessment
PDF 397.46 KB
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Abstract [+]
Proteinuria is a common incidental finding that physicians face in the inpatient and outpatient setting. Proteinuria may represent a benign pathology in asymptomatic patients, or it can be a sign of significant renal or systemic disease. The latter is usually associated with persistent proteinuria or other clinical findings such as renal failure. This article will focus on the mechanisms, causes and diagnostic approach of proteinuria. Proteinuria is a common incidental finding that physicians face in the inpatient and outpatient setting. Proteinuria may represent a benign pathology in asymptomatic patients, or it can be a sign of significant renal or systemic disease. The latter is usually associated with persistent proteinuria or other clinical findings such as renal failure. This article will focus on the mechanisms, causes and diagnostic approach of proteinuria.
Keywords
Proteinuria; Glomerular; Tubular; Nephritic; Nephrotic.
Sodium-Glucose Cotransporter-2 Inhibitors and Cardiovascular Disease: Lessons and the Future
PDF 274.70 KB
Full-Text (HTML)
Abstract [+]
Diabetes mellitus (DM), an epidemic non-communicable disease, is associated with macro- and micro-vascular complications which may result in sudden cardiac death at a young age. Sodium-glucose cotransporter-2 inhibitors (SGLT2-I) emerged as a new therapeutic option for managing DM with cardiovascular complications as well as diabetic patients with multiple risk factors. Three drugs in this class significantly reduced cardiovascular mortality and heart failure events, in both type 2 diabetes mellitus and non-diabetic patients with a reduced ejection fraction, to prevent heart failure related hospitalisation. Evidence of kidney protection was another major advantage provided in more than one study. We reviewed recent SGLT2-I related literature and discuss the benefits beyond the cardiac system.
Keywords
Diabetes mellitus (DM); Cardiovascular disease; Sodium-glucose cotransporter-2 inhibitors (SGLT2-I); Renal protection.
Leg Ulcer in Patient with Sickle Cell Disease on Hydroxyurea
PDF 310.85 KB
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Abstract [+]
Leg ulcers are a painful side-effect commonly seen in patients with long-term use of hydroxyurea. We describe an ulcer in a patient with sickle cell disease (SCD) with an 8-year history of hydroxyurea use. Wound care team used cadexomer-iodine topical
and collagenase to aid in healing. There are limited options for the treatment of these ulcers beside the cessation of hydroxyurea, a very effective drug in reducing painful sickle cell episodes. It is imperative to be aware of this complication to prevent expensive tests and further work up. Future study into alternative treatment of hydroxyurea-induced leg ulcers for sickle cell patients is necessary.
Keywords
Leg Ulcer; Sickle cell disease (SCD); Hydroxyurea.
