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Article in press
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The Catalytic Framework: Africa’s Weapon to End Acquired Immune Deficiency Syndrome by 2030
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Towards a More Sustainable Response: Strengthening the Social Agenda in the Human Immunodeficiency Virus Infection and Acquired Immune Deficiency Syndrome Epidemic
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The Time is Now for Disruptive Innovation in Pre-Exposure Prophylaxis Adherence Monitoring
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Abstract [+]
Monitoring adherence to pre-exposure prophylaxis is a critical component of reaching ending the human immunodeficiency virus infection (HIV) epidemic goals in the US. Currently, providers still depend on “self-report” pre-exposure prophylaxis (PrEP) adherence, whereby providers ask their patients about their recent pill taking habits. There appears to be growing consensus across the HIV prevention community that “self-report” is an inadequate method of identifying that is in-need of additional adherence support services. In a recent survey, 97% of providers report utilizing self-reported adherence because it is convenient, but only 10% of these providers believe it is accurate. While “self-report” is convenient, evidence and testimonials from diverse stakeholders across the HIV prevention landscape indicate that there is a desire for more accurate, effective adherence monitoring methods. In this mini-review, we will briefly synthesize the emerging evidence and propose a solution to ensure all patients receive the support needed to protect them from HIV acquisition.
Keywords
Pre-exposure prophylaxis; HIV; Adherence; Prevention; Self-report.
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Current Issue
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Exploring the Everyday Lived Experience of African American People Living with HIV/AIDS (PLWH) in the Rural South
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Abstract [+]
Aims/Objectives
Despite previous findings attesting to the syndemic nature of human immunodeficiency virus (HIV), chronic disease and mental illness coordination of these issues remains a significant barrier to initiating and maintaining the delivery of mental and physical health care to persons living with HIV (PLWH). These inequities are even greater when applied to rural settings, particularly in areas that are medically underserved. To date, there is scarce research regarding the lived experiences of African American PLWH
in rural settings. Constructivist grounded theory was used to analyze this qualitative data set. These discourses provide a rich narrative regarding effective systems of care, the context in which these processes take place and related constraints or limitations of the current systems.Methods
In-depth interviews with 24 African American PLWH both inside (N=20) and outside (N=4) of care in rural Northwestern Virginia were conducted. Rural African American PLWH were queried about their perceptions of the provision of HIV health care services, barriers to linkages to care, retention of PLWH in care, and recommendations for improving HIV health care services for rural PLWH.
Results
Participants offered insights on the linkages to health and mental health care consistent with the pattern recommended by the cascade of care (i.e. pre-screening, testing, refer to treatment, treatment and sustain treatment). Participants identified contextual factors, including traumatic events, medication (side effects), other chronic health issues, issues with the current health and mental health system, stigma, and lack of social support. We highlight PLWH’s recommendations for linking rural PLWH into care and sustaining that care.
Conclusion
We discuss the implications of these findings for programmatic development in the rural context.
Keywords
Rural African Americans living with HIV; Barriers to HIV health care; Rural South; HIV lived experience.
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Why do HIV PrEP Patients Become Lost-to-Care and How Can We Improve PrEP Retention?
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Abstract [+]
Objectives
To assess reasons for patients being lost-to-care (LTC) at an urban health center (Philadelphia, PA, USA) that provides access to oral tenofovir/emtricitabine(TDF/FTC) as pre- exposure prophylaxis(PrEP) to patients ages 13-30 years through a drop-in model of care.
Methods
Ninety-nine patients were identified as LTC based on not visiting a clinician in ≥4 months during the period April 2016-January 2017. Patients were contacted by phone/email to participate in a voluntary telephone survey regarding reasons for falling out of care. Results were analyzed descriptively.
Results
Of the 99 patients preliminarily identified as LTC, 19 completed the survey. Reason(s) for becoming LTC included: 47%(9) relocation, 11%(2) transportation difficulties to/from clinic, 26%(5) financial/insurance problems, 5%(1) perceived medication side effects, 16%(3) trouble remembering to attend appointments regularly, 5%(1) difficulty with daily medication adherence, and 0% social stigma. Furthermore, 21%(4) remain at high-risk of HIV/STI acquisition after becoming LTC. The main study limitations are selection bias and small sample size, where the small sample size did not allow for statistical significance.
Conclusion
While the major cause for becoming LTC was relocation, these findings suggest 37% of LTC incidences may be preventable with additional/up-front support. Because 21% of LTC patients remain at high-risk of HIV/STI acquisition, proactive re-engagement initiatives are potentially useful.
Keywords
HIV/AIDS; Pre-exposure prophylaxis; Retention and care; Socioeconomic factors; Adolescent Health; Lesbian/Gay/Bisexual/Transgender Persons.
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The Elderly are Facing HIV/AIDS Crisis
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HIV Infection on the Rise among Chinese College Students
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Preventable Deaths among HIV-Positive Patients: A Real-Life Perspective from a Teaching Hospital in Northern Mexico
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Previous Issue
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HIV-Related Health Status, Adherence, and Stress Coping Capacity among Men Living with HIV in Japan
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The Elderly are Facing HIV/AIDS Crisis
PDF 265.17 KB
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HIV Infection on the Rise among Chinese College Students
PDF 256.59 KB
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Preventable Deaths among HIV-Positive Patients: A Real-Life Perspective from a Teaching Hospital in Northern Mexico
PDF 440.18 KB
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Associate Editors
Samuel Kabwigu, MBchB, Mmed
Investigator, Obstetrician and Gynecologist Co-Principal Investigator for Microbicides Trials Network studies Makerere University-Johns Hopkins University Research Collaboration-MUJHU-CARE LTD Uganda
Jill E. Rowe, PhD, MPH
Assistant Professor School of Interdisciplinary Health Programs College of Health & Human Services Western Michigan University 1903 West Michigan Avenue Kalamazoo, MI 49008, USA
Glen N. Gaulton, PhD
Executive Vice Dean and Chief Scientific Officer Professor of Pathology and Laboratory Medicine Perelman School of Medicine University of Pennsylvania USA