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Volume 2, Issue 1

  • 2015, March

    original research

    Interpretation of Heart Sound Signal through Automated Artifact-Free SegmentationOpen Access

    A. Kishore Kumar and Goutam Saha*
    DOI: http://dx.doi.org/10.17140/HROJ-2-105
    PDF2.33 MB 2.33 MB
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  • 2015, March

    case report

    A Case Report of the Management of Residual Cardiovascular Risk in a Dyslipidaemic Patient with Metabolic SyndromeOpen Access

    Danish Mahmood* and Abubakar Siddique
    DOI: http://dx.doi.org/10.17140/HROJ-2-106
    PDF359.80 KB 359.80 KB
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  • 2015, March

    review

    E-Care Project: A Promising E-Platform for Optimizing Management of Chronic Heart Failure and Other Chronic DiseasesOpen Access

    Emmanuel Andrès*, Samy Talha, Mohamed Hajjam, Jawad Hajjam, Sylvie Ervé and Amir Hajjam
    DOI: http://dx.doi.org/10.17140/HROJ-2-107
    PDF1.27 MB 1.27 MB
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  • 2015, April

    original research

    The Related Factors and Clinical Predictive Value of Left Atrial Spontaneous Echo Contrast in Patient with Nonvalvular Chronic Atrial FibrillationOpen Access

    Yanmin Xu*, Bing Tian, Deepak Sharma, Xingmei Guo, Xindong Wang and Huaying Fu
    DOI: http://dx.doi.org/10.17140/HROJ-2-108
    PDF371.74 KB 371.74 KB
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  • 2015, April

    illustration

    Saddle Thrombus seen on Transthoracic Echo: A Rare Feature in Pulmonary EmbolismOpen Access

    Vineet Bhatia*, Parneesh Arora and Anil Minocha
    DOI: http://dx.doi.org/10.17140/HROJ-2-109
    PDF799.25 KB 799.25 KB
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Article in press

NOTE: The DOIs of the In-Press Articles will only function after the final publication of the articles and once they are uploaded to the Current Issues.
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Current Issue

  • 2021, April

    original research

    A Comparison of Efficacy, Safety and Cost Between MANTATM and Proglide Vascular Closure Devices Following Transfemoral Transcatheter Aortic Valve ImplantationOpen Access

    Noman Ali*, Ciprian Dospinescu, Michael S. Cunnington, Christopher J. Malkin and Daniel J. Blackman
    DOI: https://dx.doi.org/10.17140/HROJ-8-156
    PDF455.52 KB 455.52 KB
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    Abstract [+]

    Aims
    Access site vascular complications remain a recognised complication following transcatheter aortic valve implantation (TAVI). Suture-based vascular closure devices (VCDs) such as ProGlide® (Abbott Vascular Inc., Santa Clara, CA, USA) are widely used in order to achieve rapid haemostasis. The MANTATM (Essential Medical Inc., Malvern, PA, USA) is a collagen plug-based VCD which can be used as an alternative to traditional suture-based devices, but is significantly more expensive per-unit. We compare the efficacy, safety and total cost associated with the use of the MANTATM and ProGlide® VCDs.
    Methods
    This retrospective study included all consecutive patients who underwent transfemoral (TF) TAVI between November 2017-June 2018. The primary endpoints were primary access site-related VARC-2 vascular complications, VARC-2 bleeding and the overall per-patient cost incorporating treatment for complications or use of additional VCDs.
    Results
    A total of 136 patients were included in this study; 86 in the ProGlide® group and 50 in the MANTATM group. Baseline characteristics of the two groups were well-matched. Three patients in the ProGlide® group required surgical repair compared to none in the MANTATM group. However, no significant differences were observed with respect to overall primary access site-related VARC-2 vascular complications (10.5% vs. 10%; p=0.93) or VARC-2 bleeding (9.3% vs. 4.0%; p=0.25). There was no significant difference in the mean cost per patient when taking into consideration the use of additional VCDs and treatments for vascular complications (£568.79 vs. £599.95; p=0.90).
    Conclusion
    The use of the MANTATM VCD following TF TAVI is cost-neutral compared to ProGlide® VCDs, whilst being associated with no increase in VARC-2 vascular or bleeding complications.
    Keywords
    Transcatheter valve interventions; Vascular complications; Vascular closure devices (VCD).


  • 2021, April

    systematic review

    Cardiovascular Health and Healthcare Use of United States-Born and African-Born Blacks: A ReviewOpen Access

    Olubukunola Oyedele* and Dona Schneider
    DOI: https://dx.doi.org/10.17140/HROJ-8-157
    PDF547.62 KB 547.62 KB
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    Abstract [+]

    Cardiovascular disease (CVD) is the leading cause of death globally, with Blacks in the United States (U.S.) disproportionately affected. Healthcare access and utilization have been reported as risk factors for poorer cardiovascular health among several U.S.
    populations.
    Aims and Objectives
    The purpose of this systematic literature review was to examine the results of existing studies reporting on cardiovascular health and healthcare utilization by African-born compared to U. S. -born Blacks.
    Methods
    A systematic literature review was conducted using keywords and medical subject headings (MESHs) in the PUBMED, Web of Science and CINAHL electronic databases. Exclusion and inclusion criteria determined articles to be reviewed for eligibility and methodological soundness. A pooled analysis was performed on all studies.
    Results
    Only seven studies met inclusion criteria. Four compared U. S. -born with African-born Blacks residing in the United States, while three compared U. S. -born Blacks with Blacks residing elsewhere. None of the studies examined the associations between healthcare utilization and cardiovascular health for these populations.
    Conclusion
    The results of this review indicate a need to examine the impact of healthcare utilization for increasing awareness, prevention and treatment of CVD in Blacks who reside in the United States regardless of their nativity.
    Keywords
    Cardiovascular health; African-born Blacks; U.S-born blacks; Healthcare utilization.
    Abbreviations
    CVD: Cardiovascular disease; US: United States; MESHs: Medical subject headings; sBP: Systolic blood pressure; dBP: Diastolic blood pressure; BMI: Body mass index; BP: Blood pressure.


  • 2021, July

    case report

    Ebstein’s Anomaly, Possible Newly Implicated Drug Aetiology? A Case ReportOpen Access

    Barakat A. Animasahun*, Omotola A. Ajayi, Faith O. Lawani and Elizabeth A. Disu
    DOI: https://dx.doi.org/10.17140/HROJ-8-158
    PDF402.47 KB 402.47 KB
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  • 2021, December

    original research

    Assessment of Level of Awareness Towards Radiation Protection Among the Staff Working at Angiography Suite at Public HospitalsOpen Access

    Ruby Niaz, Syed N. Hyder*, Usaid Ahmed and Munawer Ghous
    DOI: https://dx.doi.org/10.17140/HROJ-8-159
    PDF436.13 KB 436.13 KB
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    Abstract [+]

    Introduction
    Several challenges with radiation protection and safety culture in radiology departments needs to be addressed as few studies done in this aspect in our country. Especially with regard to the awareness about radiation protection, hazards, dosimetry usage and measurement.
    Objective
    The objective of this study is to find knowledge about radiation exposure hazard and practices among various auxiliary staff working in radiation units.
    Material and Methods
    Cross-sectional study done by using stratified random sampling method. A questionnaire made to check the awareness level of the radiological staff regarding radiation protection working in angiography suite. The questionnaire had two parts with various questions about radiation protection measures and safety related knowledge for staff and patient. Data collected from angiography suite of three public sector hospitals of Lahore, Pakistan. All the data entered in statistical package for the social science (SSPS) version 16 and analyzed for statistically significant outcomes.
    Results
    Total of 67 staff members were included in this study from three different public sector hospitals, 55.2% were males 44.77% were females. Twenty-nine (29) persons belonged to the age group of 20-30-years. Twenty (20) doctors, 21 nurses, 12 radiographers and 14 paramedical staff were included. 89.55% staff members were aware of radiation hazard. 55.22% had training on radiation protection and 44.77%. 56.71% were aware of dosimeter. Only 16% were aware of as low as reasonably achievable (ALARA).
    Conclusion
    The radiological staff members were partially aware about radiation hazards and radiation safety. They were lacking from training and workshops. Essential steps required to develop nationwide strategies for improving the situation and maintaining a safe working environment.
    Keywords
    Angiography; Radiation hazards; Radiation protection; X-ray; Radiation protection devices.


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Previous Issue

  • 2020, February

    case illustration

    Dynamic Shape Change of an Aortic Valve Cusp Perforation on 3D Transesophageal EchocardiogramOpen Access

    Maedeh Ganji, Jose Ruiz, Robert Percy, Emil Missov and Srinivasan Sattiraju
    DOI: https://dx.doi.org/10.17140/HROJ-7-152
    PDF301.72 KB 301.72 KB
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  • 2020, March

    case report

    Advanced Heart Failure Exacerbated by Discreet Left Ventricular Lead Non-CaptureOpen Access

    Jon Krathen*, John Costello, Mark Moshiyakhov, Raphael Corbisiero and Kulpreet Barn
    DOI: https://dx.doi.org/10.17140/HROJ-7-153
    PDF698.54 KB 698.54 KB
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    Abstract [+]

    This case report illustrates a challenging case of worsening heart failure in a previously well-compensated patient with unclear etiology. Further workup revealed the patient’s cardiac resynchronization therapy-defibrillator (CRT-D) left ventricle (LV) lead was losing capture during positional changes. This case demonstrates the importance of device optimization, as well as electrocardiogram (ECG) monitoring to elucidate possible causes of acute systolic heart failure.

    Keywords

    Cardiac resynchronization; cardiac resynchronization therapy (CRT); Systolic heart failure; Lead positioning;
    Advanced heart failure.


  • 2020, June

    case report

    A Rare Case of Giant Cell MyocarditisOpen Access

    Althea C. G. Neblett*
    DOI: https://dx.doi.org/10.17140/HROJ-7-154
    PDF662.00 KB 662.00 KB
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    Abstract [+]

    Giant cell myocarditis is a rare condition first described in 1905. It has a reported incidence range from 0.007% to 0.051%. It affects female and male individuals, equally, and usually occurs in young and middle-aged persons. The underlying aetiology of giant cell myocarditis is unknown but it is thought to be mediated by T-lymphocytes. Diagnosis is made via histological examination of myocardial tissue and is characterized by a mixed inflammatory cell infiltrate with multinucleated giant cells and cardiomyocyte necrosis, predominantly affecting the ventricles. The following report describes a rare case of giant cell myocarditis in a 71-year-old man with a history of hypertension and heart failure, who died while waiting to be seen in the emergency department. Autopsy findings revealed an enlarged, dilated heart with histologic features in keeping with giant cell myocarditis, along with features of heart failure. Diagnosis of giant cell myocarditis is less common in the elderly age group, possibly due to a less severe disease process in this age group and it may be misdiagnosed because older individuals may have other cardiovascular diseases (CVDs).

    Keywords

    Myocarditis; Giant cell myocarditis; Autopsy; Elderly, Cardiovascular.


  • 2020, November

    original research

    Histopathological Analysis of the Pro-Arrhythmogenic Changes in a Suspected Chagas Disease Sudden DeathOpen Access

    Héctor O. Rodríguez*
    DOI: https://dx.doi.org/10.17140/HROJ-7-155
    PDF430.76 KB 430.76 KB
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    Abstract [+]

    Background
    Sudden death is the principal cause of fatality in Chagas disease, afflicting to non-symptomatic patients younger than 50-years. For this, sudden death associated with chagasic malignant arrhythmias is underdiagnosed and their pathophysiological basis is poorly understood.
    Aims
    In this sense, this work aimed to analyze the histopathological alterations in cardiac structures specialized in the generation/conduction of action potential in an anatomopathological case of non-diagnosed sudden death living in a Chagasic endemic area.
    Methods
    The donor was a woman, 62-year-old, which ingressed without vital signs to the emergency room of “Antonio María Pineda” hospital, without any apparent antecedents of cardiac disease. The gross examination was normal, with no external evidence of structural/ischemic disease.
    Results
    Microscopic examination revealed nodal like cell depopulation, microvascular disturbances, chronic myocarditis with mononuclear and mast cell infiltrate plus extracellular matrix reaction, and profuse damage of neural structures placed in nodal region. amastigote nest of Trypanosoma cruzi (T. cruzi) was detected.
    Conclusion
    These findings suggest a complex association among parasite persistence, sinus disease, micro-ischemia foci, and neural inflammation in the genesis of malignant arrhythmias of Chagas disease despite the absence of structural disease or massive necrosis. It is important to perform a protocol of examination for no explained sudden death cases in chagasic endemic countries, to avoid misdiagnosed of sudden death associated with Chagas disease.


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    Editor-in-Chief

    Giuseppe De Luca, MD, PhD


    Aggregate Professor of Cardiology
    Chief Interventional Cardiology
    Eastern Piedmont University
    C.so Mazzini 18, 28100
    Novara, Italy

    Associate Editors

    Anastasios (Tassos) Lymperopoulos, BPharm, MSc, PhD, FAHA


    Assistant Professor of Pharmacology
    Department of Pharmaceutical Sciences
    College of Pharmacy
    Nova Southeastern University
    3200 S. University Dr
    Health Professions Division (Terry)
    Bldg/Room 1338
    Fort Lauderdale, FL 33328, USA

    Majid Kalani, MD, PhD


    Consultant Interventional Cardiologist
    Department of Cardiology
    Danderyd University Hospital &
    Karolinska Institute
    Stockholm, Sweden

    Muralidhar Padala, PhD


    Director and Assistant Professor
    Structural Heart Research & Innovation Lab
    Division of Cardiothoracic Surgery
    Emory University
    380B, Northyards Blvd
    Atlanta, GA 30313, USA

    Zhonghua Sun, PhD


    Associate Professor | Medical Imaging Discipline
    Department of Imaging and Applied Physics
    Curtin University
    GPO Box U1987, Perth WA 6845, Australia

    Our editorial team


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