Volume 2, Issue 1

Volume 2, Issue 1

2015, March

original research

Interpretation of Heart Sound Signal through Automated Artifact-Free Segmentation

A. Kishore Kumar and Goutam Saha*
DOI: http://dx.doi.org/10.17140/HROJ-2-105

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2015, March

A Case Report of the Management of Residual Cardiovascular Risk in a Dyslipidaemic Patient with Metabolic Syndrome

Danish Mahmood* and Abubakar Siddique
DOI: http://dx.doi.org/10.17140/HROJ-2-106

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2015, March

review

E-Care Project: A Promising E-Platform for Optimizing Management of Chronic Heart Failure and Other Chronic Diseases

Emmanuel Andrès*, Samy Talha, Mohamed Hajjam, Jawad Hajjam, Sylvie Ervé and Amir Hajjam
DOI: http://dx.doi.org/10.17140/HROJ-2-107

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2015, April

original research

The Related Factors and Clinical Predictive Value of Left Atrial Spontaneous Echo Contrast in Patient with Nonvalvular Chronic Atrial Fibrillation

Yanmin Xu*, Bing Tian, Deepak Sharma, Xingmei Guo, Xindong Wang and Huaying Fu
DOI: http://dx.doi.org/10.17140/HROJ-2-108

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2015, April

illustration

Saddle Thrombus seen on Transthoracic Echo: A Rare Feature in Pulmonary Embolism

Vineet Bhatia*, Parneesh Arora and Anil Minocha
DOI: http://dx.doi.org/10.17140/HROJ-2-109

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Article in press

2021, April

original research

A Comparison of Efficacy, Safety and Cost Between MANTATM and Proglide Vascular Closure Devices Following Transfemoral Transcatheter Aortic Valve Implantation

Noman Ali*, Ciprian Dospinescu, Michael S. Cunnington, Christopher J. Malkin and Daniel J. Blackman
DOI: https://dx.doi.org/10.17140/HROJ-8-156

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Abstract [+]

Aims
Access site vascular complications remain a recognised complication following transcatheter aortic valve implantation (TAVI). Suture-based vascular closure devices (VCDs) such as ProGlide® (Abbott Vascular Inc., Santa Clara, CA, USA) are widely used in order to achieve rapid haemostasis. The MANTATM (Essential Medical Inc., Malvern, PA, USA) is a collagen plug-based VCD which can be used as an alternative to traditional suture-based devices, but is significantly more expensive per-unit. We compare the efficacy, safety and total cost associated with the use of the MANTATM and ProGlide® VCDs.
Methods
This retrospective study included all consecutive patients who underwent transfemoral (TF) TAVI between November 2017-June 2018. The primary endpoints were primary access site-related VARC-2 vascular complications, VARC-2 bleeding and the overall per-patient cost incorporating treatment for complications or use of additional VCDs.
Results
A total of 136 patients were included in this study; 86 in the ProGlide® group and 50 in the MANTATM group. Baseline characteristics of the two groups were well-matched. Three patients in the ProGlide® group required surgical repair compared to none in the MANTATM group. However, no significant differences were observed with respect to overall primary access site-related VARC-2 vascular complications (10.5% vs. 10%; p=0.93) or VARC-2 bleeding (9.3% vs. 4.0%; p=0.25). There was no significant difference in the mean cost per patient when taking into consideration the use of additional VCDs and treatments for vascular complications (£568.79 vs. £599.95; p=0.90).
Conclusion
The use of the MANTATM VCD following TF TAVI is cost-neutral compared to ProGlide® VCDs, whilst being associated with no increase in VARC-2 vascular or bleeding complications.
Keywords
Transcatheter valve interventions; Vascular complications; Vascular closure devices (VCD).

2021, April

systematic review

Cardiovascular Health and Healthcare Use of United States-Born and African-Born Blacks: A Review

Olubukunola Oyedele* and Dona Schneider
DOI: https://dx.doi.org/10.17140/HROJ-8-157

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Abstract [+]

Cardiovascular disease (CVD) is the leading cause of death globally, with Blacks in the United States (U.S.) disproportionately affected. Healthcare access and utilization have been reported as risk factors for poorer cardiovascular health among several U.S.
populations.
Aims and Objectives
The purpose of this systematic literature review was to examine the results of existing studies reporting on cardiovascular health and healthcare utilization by African-born compared to U. S. -born Blacks.
Methods
A systematic literature review was conducted using keywords and medical subject headings (MESHs) in the PUBMED, Web of Science and CINAHL electronic databases. Exclusion and inclusion criteria determined articles to be reviewed for eligibility and methodological soundness. A pooled analysis was performed on all studies.
Results
Only seven studies met inclusion criteria. Four compared U. S. -born with African-born Blacks residing in the United States, while three compared U. S. -born Blacks with Blacks residing elsewhere. None of the studies examined the associations between healthcare utilization and cardiovascular health for these populations.
Conclusion
The results of this review indicate a need to examine the impact of healthcare utilization for increasing awareness, prevention and treatment of CVD in Blacks who reside in the United States regardless of their nativity.
Keywords
Cardiovascular health; African-born Blacks; U.S-born blacks; Healthcare utilization.
Abbreviations
CVD: Cardiovascular disease; US: United States; MESHs: Medical subject headings; sBP: Systolic blood pressure; dBP: Diastolic blood pressure; BMI: Body mass index; BP: Blood pressure.

2021, July

case report

Ebstein’s Anomaly, Possible Newly Implicated Drug Aetiology? A Case Report

Barakat A. Animasahun*, Omotola A. Ajayi, Faith O. Lawani and Elizabeth A. Disu
DOI: https://dx.doi.org/10.17140/HROJ-8-158

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Current Issue

2020, February

case illustration

Dynamic Shape Change of an Aortic Valve Cusp Perforation on 3D Transesophageal Echocardiogram

Maedeh Ganji, Jose Ruiz, Robert Percy, Emil Missov and Srinivasan Sattiraju
DOI: https://dx.doi.org/10.17140/HROJ-7-152

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2020, March

case report

Advanced Heart Failure Exacerbated by Discreet Left Ventricular Lead Non-Capture

Jon Krathen*, John Costello, Mark Moshiyakhov, Raphael Corbisiero and Kulpreet Barn
DOI: https://dx.doi.org/10.17140/HROJ-7-153

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Abstract [+]

This case report illustrates a challenging case of worsening heart failure in a previously well-compensated patient with unclear etiology. Further workup revealed the patient’s cardiac resynchronization therapy-defibrillator (CRT-D) left ventricle (LV) lead was losing capture during positional changes. This case demonstrates the importance of device optimization, as well as electrocardiogram (ECG) monitoring to elucidate possible causes of acute systolic heart failure.

Keywords

Cardiac resynchronization; cardiac resynchronization therapy (CRT); Systolic heart failure; Lead positioning;
Advanced heart failure.

2020, June

case report

A Rare Case of Giant Cell Myocarditis

Althea C. G. Neblett*
DOI: https://dx.doi.org/10.17140/HROJ-7-154

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Abstract [+]

Giant cell myocarditis is a rare condition first described in 1905. It has a reported incidence range from 0.007% to 0.051%. It affects female and male individuals, equally, and usually occurs in young and middle-aged persons. The underlying aetiology of giant cell myocarditis is unknown but it is thought to be mediated by T-lymphocytes. Diagnosis is made via histological examination of myocardial tissue and is characterized by a mixed inflammatory cell infiltrate with multinucleated giant cells and cardiomyocyte necrosis, predominantly affecting the ventricles. The following report describes a rare case of giant cell myocarditis in a 71-year-old man with a history of hypertension and heart failure, who died while waiting to be seen in the emergency department. Autopsy findings revealed an enlarged, dilated heart with histologic features in keeping with giant cell myocarditis, along with features of heart failure. Diagnosis of giant cell myocarditis is less common in the elderly age group, possibly due to a less severe disease process in this age group and it may be misdiagnosed because older individuals may have other cardiovascular diseases (CVDs).

Keywords

Myocarditis; Giant cell myocarditis; Autopsy; Elderly, Cardiovascular.

2020, November

original research

Histopathological Analysis of the Pro-Arrhythmogenic Changes in a Suspected Chagas Disease Sudden Death

Héctor O. Rodríguez*
DOI: https://dx.doi.org/10.17140/HROJ-7-155

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Abstract [+]

Background
Sudden death is the principal cause of fatality in Chagas disease, afflicting to non-symptomatic patients younger than 50-years. For this, sudden death associated with chagasic malignant arrhythmias is underdiagnosed and their pathophysiological basis is poorly understood.
Aims
In this sense, this work aimed to analyze the histopathological alterations in cardiac structures specialized in the generation/conduction of action potential in an anatomopathological case of non-diagnosed sudden death living in a Chagasic endemic area.
Methods
The donor was a woman, 62-year-old, which ingressed without vital signs to the emergency room of “Antonio María Pineda” hospital, without any apparent antecedents of cardiac disease. The gross examination was normal, with no external evidence of structural/ischemic disease.
Results
Microscopic examination revealed nodal like cell depopulation, microvascular disturbances, chronic myocarditis with mononuclear and mast cell infiltrate plus extracellular matrix reaction, and profuse damage of neural structures placed in nodal region. amastigote nest of Trypanosoma cruzi (T. cruzi) was detected.
Conclusion
These findings suggest a complex association among parasite persistence, sinus disease, micro-ischemia foci, and neural inflammation in the genesis of malignant arrhythmias of Chagas disease despite the absence of structural disease or massive necrosis. It is important to perform a protocol of examination for no explained sudden death cases in chagasic endemic countries, to avoid misdiagnosed of sudden death associated with Chagas disease.

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Previous Issue

2019, February

letter to the editor

“The Moustache Sign”: A Common Morphological Characteristic in Cardiovascular Disease Treatment

Vineet Bhatia*, Parneesh Arora, Anunay Gupta, Suman Bhandari and Upendra Kaul
DOI: https://dx.doi.org/10.17140/HROJ-6-148

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2019, June

original research

Changes on Electrocardiographic Patterns and Associated Factors among Chronic Obstructive Pulmonary Disease Patients

Wondu Reta Demissie*, Samuel Tadessa, Elsah Tegene and Tewodros G. Mariam
DOI: https://dx.doi.org/10.17140/HROJ-6-149

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2019, August

case series

Malignant Restenosis and Progression of Disease in Psoriatic Patients Undergoing Coronary Interventions: Is it the Koebner’s Phenomena to Blame?

Vineet Bhatia*, Parneesh Arora, Vineet Relhan and Upendra Kaul
DOI: https://dx.doi.org/10.17140/HROJ-6-150

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Abstract [+]

Severe psoriasis is associated with an enhanced risk of cardiovascular (CV) diseases. The potential impact of psoriasis on the prognosis following coronary revascularization (percutaneous coronary intervention (PCI) or surgical) is not well studied and sparse data available in literature points towards a grim long-term prognosis. The following two cases highlight this phenomenon. We also discuss the plausible reasons responsible for the poor prognosis and propose some possible mechanisms for the same.

2019, October

review

Pulmonary Artery Hypertension in Children Living with Sickle Cell Anaemia

Barakat A. Animasahun* and Moriam O. Lamina
DOI: https://dx.doi.org/10.17140/HROJ-6-151

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Abstract [+]

Pulmonary artery hypertension (PAH) ultimately leads to straining of the right ventricle and increases the risk of heart failure in affected patients. Its clinical presentation is similar to that of many other diseases thus delaying the diagnosis until the disease is far advanced. It remains one of the leading causes of death in adults with sickle cell anaemia (SCA) worldwide. It confers a high risk of death with two-year mortality rates as high as 40-50% even at modest elevation of pulmonary artery pressure. Median survival age after detection of the disease is said to be 25.6-months. Early detection of elevated pulmonary artery pressure in childhood and appropriate intervention by optimization of anti-haemolytic therapy may prevent the progression of this complication. The current writes up is a review of literatures on pulmonary artery hypertension among children with sickle cell anaemia. This will give information which will aid early diagnosis and treatment of pulmonary artery hypertension among children with sickle cell anaemia. This will ultimately improve the quality of life of children with sickle cell anaemia and reduce morbidity and mortality from the disease in adults and children living with sickle cell anaemia.

Keywords

Sickle cell anaemia; Pulmonary artery hypertension; Children.

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Editor-in-Chief

Giuseppe De Luca, MD, PhD

Aggregate Professor of Cardiology
Chief Interventional Cardiology
Eastern Piedmont University
C.so Mazzini 18, 28100
Novara, Italy

Associate Editors

Anastasios (Tassos) Lymperopoulos, BPharm, MSc, PhD, FAHA

Assistant Professor of Pharmacology
Department of Pharmaceutical Sciences
College of Pharmacy
Nova Southeastern University
3200 S. University Dr
Health Professions Division (Terry)
Bldg/Room 1338
Fort Lauderdale, FL 33328, USA

Majid Kalani, MD, PhD

Consultant Interventional Cardiologist
Department of Cardiology
Danderyd University Hospital &
Karolinska Institute
Stockholm, Sweden

Muralidhar Padala, PhD

Director and Assistant Professor
Structural Heart Research & Innovation Lab
Division of Cardiothoracic Surgery
Emory University
380B, Northyards Blvd
Atlanta, GA 30313, USA

Zhonghua Sun, PhD

Associate Professor | Medical Imaging Discipline
Department of Imaging and Applied Physics
Curtin University
GPO Box U1987 Perth WA 6845
Australia

Our editorial team

Advertisement

Interpretation of Heart Sound Signal through Automated Artifact-Free Segmentation

PDF 2.33 MB

A Case Report of the Management of Residual Cardiovascular Risk in a Dyslipidaemic Patient with Metabolic Syndrome

PDF 359.80 KB

E-Care Project: A Promising E-Platform for Optimizing Management of Chronic Heart Failure and Other Chronic Diseases

PDF 1.27 MB

The Related Factors and Clinical Predictive Value of Left Atrial Spontaneous Echo Contrast in Patient with Nonvalvular Chronic Atrial Fibrillation

PDF 371.74 KB

Saddle Thrombus seen on Transthoracic Echo: A Rare Feature in Pulmonary Embolism

PDF 799.25 KB

Article in press

A Comparison of Efficacy, Safety and Cost Between MANTATM and Proglide Vascular Closure Devices Following Transfemoral Transcatheter Aortic Valve Implantation

Provisional PDF 455.52 KB

Abstract [+]

Cardiovascular Health and Healthcare Use of United States-Born and African-Born Blacks: A Review

Provisional PDF 547.41 KB

Abstract [+]

Ebstein’s Anomaly, Possible Newly Implicated Drug Aetiology? A Case Report

Provisional PDF 402.47 KB

Current Issue

Dynamic Shape Change of an Aortic Valve Cusp Perforation on 3D Transesophageal Echocardiogram

PDF 301.72 KB

Advanced Heart Failure Exacerbated by Discreet Left Ventricular Lead Non-Capture

PDF 698.54 KB

Abstract [+]

A Rare Case of Giant Cell Myocarditis

PDF 662.00 KB

Abstract [+]

Histopathological Analysis of the Pro-Arrhythmogenic Changes in a Suspected Chagas Disease Sudden Death

PDF 430.76 KB

Abstract [+]

Previous Issue

“The Moustache Sign”: A Common Morphological Characteristic in Cardiovascular Disease Treatment

PDF 730.37 KB

Changes on Electrocardiographic Patterns and Associated Factors among Chronic Obstructive Pulmonary Disease Patients

PDF 449.30 KB

Malignant Restenosis and Progression of Disease in Psoriatic Patients Undergoing Coronary Interventions: Is it the Koebner’s Phenomena to Blame?

PDF 275.33 KB

Abstract [+]

Pulmonary Artery Hypertension in Children Living with Sickle Cell Anaemia

PDF 328.61 KB

Abstract [+]

Connect with us

Editor-in-Chief

Giuseppe De Luca, MD, PhDAggregate Professor of Cardiology Chief Interventional Cardiology Eastern Piedmont University C.so Mazzini 18, 28100 Novara, Italy

Associate Editors

Anastasios (Tassos) Lymperopoulos, BPharm, MSc, PhD, FAHAAssistant Professor of Pharmacology Department of Pharmaceutical Sciences College of PharmacyNova Southeastern University 3200 S. University Dr Health Professions Division (Terry) Bldg/Room 1338 Fort Lauderdale, FL 33328, USA

Majid Kalani, MD, PhDConsultant Interventional Cardiologist Department of Cardiology Danderyd University Hospital & Karolinska Institute Stockholm, Sweden

Muralidhar Padala, PhDDirector and Assistant Professor Structural Heart Research & Innovation Lab Division of Cardiothoracic Surgery Emory University 380B, Northyards Blvd Atlanta, GA 30313, USA

Zhonghua Sun, PhDAssociate Professor | Medical Imaging Discipline Department of Imaging and Applied Physics Curtin University GPO Box U1987 Perth WA 6845 Australia

Our editorial team

Giuseppe De Luca, MD, PhD

Aggregate Professor of Cardiology
Chief Interventional Cardiology
Eastern Piedmont University
C.so Mazzini 18, 28100
Novara, Italy

Anastasios (Tassos) Lymperopoulos, BPharm, MSc, PhD, FAHA

Assistant Professor of Pharmacology
Department of Pharmaceutical Sciences
College of Pharmacy
Nova Southeastern University
3200 S. University Dr
Health Professions Division (Terry)
Bldg/Room 1338
Fort Lauderdale, FL 33328, USA

Majid Kalani, MD, PhD

Consultant Interventional Cardiologist
Department of Cardiology
Danderyd University Hospital &
Karolinska Institute
Stockholm, Sweden

Muralidhar Padala, PhD

Director and Assistant Professor
Structural Heart Research & Innovation Lab
Division of Cardiothoracic Surgery
Emory University
380B, Northyards Blvd
Atlanta, GA 30313, USA

Zhonghua Sun, PhD

Associate Professor | Medical Imaging Discipline
Department of Imaging and Applied Physics
Curtin University
GPO Box U1987 Perth WA 6845
Australia