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  • 2019, December

    case report

    The Importance of Enzyme Substitution Therapy in Early Pancreas Exocrines of InsufficiencyOpen Access

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    Abstract [+]


    Functional disorders of the digestive tract are a common occurrence in the doctor’s office. In addition to functional dyspepsia, 35% of dyspepsia are unresolved dyspepsia, which are a symptom of the early stage of pancreatic exocrine insufficiency.


    Based on clinical experience, we can suspect and detect chronic pancreatic insufficiency at an early stage, which is the aim of this paper.


    To demonstrate the efficacy of enzyme replacement therapy in the early stage of pancreatic exocrine insufficiency using the case report of the patient.


    Results confirms significance and effectiveness of creon as an enzyme replacement therapy in the treatment of malabsorption and maldigestion.


    Creon (pancreatin) showed great effect in the treatment of dyspepsia and anorexia nervosa, body mass index (BMI) for 30 days increased from 15.9 to 17.4, which leads us to the conclusion that unrecognized chronic pancreatic insufficiency can be expected in long-term dyspepsia.


    Chronic pancreatic insufficiency; Enzyme; Body mass index (BMI); Digestive tract.

About the Journal

The word ‘Gastro’ is used in conjunction with many words like Gastrology, Gastroenteritis, Gastrocaine, Gastrointestinal system, etc.

Gastro – Open Journal (GOJ) aims to publish the current breakthroughs of the digestive system and its related diseases.

However, Openventio aims to widespread all the detailed matters related to the gastro research through its Open Journal to all the scientific community for the welfare of the patients.

Aims and Scope

Gastro – Open Journal (GOJ) is dedicated to the open dissemination and robust discussion in the area of gastroenterology and its related fields.

GOJ covers a wide array of subjects as given below

  • Irritable bowel syndrome
  • Ulcers
  • Endoscopy
  • Digestive disorders
  • Tumors in gastrointestinal tract
  • Gastrointestinal cancer
  • Gastrointestinal surgery
  • Appendicitis
  • Gastrointestinal Diseases
  • Appendicitis
  • Bacterial or viral infections, Gastrointectinal infection
  • Constipation
  • Diverticulitis
  • Aneurysm

Submissions for this Journal are accepted from the very basic gastroenterology to the recent advancements of treatment. This journal encourage submissions from the field of basic Gastroentology to advanced Gastroentology.

GOJ is also specialized in cross-disciplinary communication. Therefore, papers relating to some combination of different scholarly disciplines or relating comorbidities with gastroenterology diseases are welcome to submit for publication. Our Open Journal also encourages the papers related to study the role of Epigenetics in Gastroenterology since recently there are many signs of progress in the identification of genetic factors associated with IBD and discuss epigenetic mechanisms that could affect development and progression of gastrointestinal diseases.1,2

The audience of GOJ includes gastroenterologists, pediatrician, surgeons, physicians, veterinarians, hepatologists, clinicians, surgical investigators, practitioners, educators, surgical nurse, and students.

The journal accepts all types of articles such as original research, review, case-report, mini-review, editorial, short-communication, book-review, opinion, commentary, letter to the Editor, conference proceedings, technical report, errata, illustrations, etc.

We are open to receive comments or any corrections from any potential scientists to improve the quality of our Journal.


1. Ventham NT, Kennedy NA, Nimmo ER, Satsangi J. Beyond gene discovery in inflammatory bowel disease: the emerging role of epigenetics. Gastroenterology. 2013; 145: 293-308.

2. Jinghong Chen, John H Winston, Yu Fu, et al. Genesis of anxiety, depression, and ongoing abdominal discomfort in ulcerative colitis-like colon inflammation. Am J Physiol Regul Integr Comp Physiol. 2015; 308: R18-R27.