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  • 2020, June

    review

    Photobiomodulation in Cells’ RepairOpen Access

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    Abstract [+]

    Photobiomodulation is a non-invasive treatment modality acting at different biological levels through the non-thermal transfer of photons to the living matter via a photoelectric effect, inducing photochemical reactions in treated cells. The objectives of this article is to review the literature on Photobiomodulation, its different fields of application and mechanisms of action, for establishing a comprehensive summary of evidence. The search strategy initially run searches in scientific databases MEDLINE,
    PubMed, EMBASE and Cochrane registries from 1990 up to March 2020, with entries Photobiomodulation, LLLT-LEDT, PDT, Photobiology, Cytochrome c Oxidase. Selection criteria was based on preferably inclusion of randomized clinical trials (RCTs), systematic reviews (SR) and studies providing qualitative and quantitative data with the best consistency, in a field where heterogeneity of light parameters is often a difficulty to comparison of findings. Publised expert opinions were also considered. A total of 80 publications were reviewed out of a thousand obtained from databases, among which were retained 9 RCTs, 6 systematic reviews, 3 meta-analysis and 2 case-reports. Differences were found in treatment parameters as wavelength, dosage, energy output, treatment length, performances of light-sources, quantity of diodes and single power of these, which may explain the paucity of high-level body of evidence in Cochrane databases. However, numerous state-of-the- art researches are also found, led by dedicated research teams paving the way to standardized methods of evaluation and comprehension of light-biological-tissues interaction and optimization of outcomes in a promising field.
    Keywords
    PhotoBioModulation; Low-Level-Laser-Therapy (LLLT); Light emitting diodes (LED); Biophotons-mitochondria; Adenosine-triphosphate (ATP); Inflammation-pain-skin rejuvenation; Photo dynamic therapy (PDT); Photobiology.


  • 2020, January

    letter to the editor

    Squamous Melanocytic Tumour at an Unusual Site: An Uncommon Case and Literature ReviewOpen Access

    PDF478.58 KB 478.58 KB
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    Abstract [+]

    We herein present a case report of a 60-year-old male patient diagnosed with squamous-melanocytic tumour (SMT) in his anal region, comprised of two intermingled different phenotypic lesions. This dual tumour is quite uncommon and could potentially be challenging on both diagnose and also management. It is the first case reported on this location, moreover, the lack of consensus for these lesions makes it difficult to classify them. We reviewed the literature of similar SMT’s and discussed its histogenesis. As they are rare, their biological behavior and potential metastasis remain unclear. Therefore, close follow-up is advised.

    Keywords

    Combined neoplasia; Squamous-melanocytic tumour; Uncertain; Anal canal.


  • 2020, January

    brief report

    The Skinny on Moisturizers: A Brief ReportOpen Access

    PDF407.59 KB 407.59 KB
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    Abstract [+]

    Objective

    To compare the effectiveness of 5 different skin moisturizers using JELL-O® as a model for the human skin.

    Methods

    In this study five different moisturizers (Equate®, Burt’s Bees®, Suave®, Aveeno® and Vaseline®) were applied to equivalent samples of JELL-O®. Observations were made over a 12-day period and data was collected at 15 different time intervals. The primary outcome was the height (cm) and weight (g) of the JELL-O® sample at each time interval. The study was an ex vivo experiment conducted in a home laboratory. No Institutional Review Board (IRB) approval was required since the research does not involve living organisms.

    Results

    Overall, the JELL-O® sample that had the Vaseline® applied on it had the lowest loss of height and weight. The height stayed at 100% of its original value and the weight only decreased to 97.2% of the original value by the end of the observation period. In contrast, the sample which had Suave® applied to the surface its height and weight decrease the most (42% and 28% respectively). The other moisturizers had effects intermediate between these two extremes.

    Conclusion

    Based on this ex vivo head to head study using JELL-O® as a model for the human skin the 5 moisturizers examined had widely differing levels of effectiveness with Vaseline® appearing to be the most protective against evaporative losses and Suave® appearing to be the least.

    Keywords

    Moisturizers; Dry skin; Different moisturizers; Skin lotions; Vaseline® effectiveness.


  • 2019, November

    case report

    Allergic Contact Dermatitis by Beryllium Chloride as Unique Sensitivity: A Case ReportOpen Access

    PDF372.73 KB 372.73 KB
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    Abstract [+]

    Beryllium can be found in silver alloy, in costume jewelry and in dental prosthesis. It is also used in aerospace industry and might be also found in precision instruments. Pure contact dermatitis to Beryllium has never been described as in this case associated with allergic contact dermatitis to jewelry. Most reports of Beryllium contact dermatitis are related to dental prosthesis and most of the cases we have seen Beryllium allergic contact dermatitis is associated with other positive allergens. We believe that this metal should be added to the dental screening as according to our findings.

    Keywords

    Beryllium; Jewelry; Allergy; Skin allergy; Allergic contact dermatitis.


About the Journal

Dermatology – Open Journal (DRMTOJ) is an online open access portal which explores all aspects of Dermatology and its related disciplines.

Dermatology is a branch of science that deals with the hair, scalp, skin & nails and its related diseases. Cosmetology also falls under the wide ambit of dermatology.

Openventio is dedicated to act as an open access portal to all dermatology professionals across the globe who wants to stay abreast of the latest advancements in the field of dermatology.

Aims and Scope

Dermatology – Open Journal wants to position itself as a focal point for the dermatology community to discuss all issues related to dermatology, venereology, leprology, and all allied subjects.
DRMTOJ covers a wide array of subjects as given below

  • Cosmetic dermatology
  • Dermatopathology
  • Immuno dermatology
  • Acne treatment
  • Bedsores treatment
  • Decubitus ulcer
  • Chronic furuncles
  • Lichen planus
  • Epidermal cells
  • Skin disease
  • Atopic dermatitis
  • Teledermatology
  • Genodermatoses
  • Hereditary diseases
  • Atopic dermatitis
  • Psoriasis
  • Alopecia areata
  • Blistering diseases
  • Inherited skin diseases
  • Molecular genetics

Openventio encourages documentation among the ever growing medical community to ensure data gets recorded and passed on to new practitioners in the field of medicine.

Submissions for this journal are accepted from all practitioners and students, experts in the field to novices who are just starting to learn and understand dermatology.

The contributors of DRMTOJ includes doctors, nurses, research assistants, local community practitioners, manufacturers, and students of various universities and general communities from different parts of the world.

The journal welcomes all types of articles such as original research, review, case-report, mini-review, editorial, short-communication, book review, opinion, commentary, letter to the editor, conference proceedings, technical report, errata, illustrations, etc.

We are open to receive comments or any corrections from subject experts to improve the quality of our journal.