C. V. Rao, PhD

Professor of Cell Biology, Molecular and Human Genetics,Obstetrics and Gynecology
Director of Reproduction and Devolopment Program
Herbert Wertheim College of Medicine
Florida International University
Modesto A. Maidique Campus, GL495C
11200 SW 8th Street
Miami, Florida 33199, USA

Biography

C.V. Rao is one of the world’s leading experts in LH/hCG actions in non gonadal tissues in the body. More than 36 years of his research has led to wide spread recognition of these hormones action in health and disease and to potential novel therapeutic uses of hCG in reproductive medicine, infectious and autoimmune diseases, cancers, etc. He has extensively lectured on these research developments at various universities in U.S and throughout the world and in national and international scientific meetings. He has published more than 240 peer-reviewed journal articles, 350 abstracts and 36 book chapters. His research has almost been continuously funded for more than 30 years, mostly by NIH. He has taught and trained more than 100 postdoctoral and clinical fellows, residents and students. He serves as an editorial board member for numerous scientific journals. He has been an organizing committee member of numerous national and international scientific meetings. He was a member of Human Embryology and Development 1 Study Section at National Institutes of Health from 1998 to 2002. Before joining Florida International University College of Medicine in July 2008, Dr. Rao held the positions of Professor of Obstetrics, Gynecology and Womens Health, Professor of Biochemistry and Molecular Biology and Director of Division of Research in the Department of Obstetrics, Gynecology and Womens Health at the University of Louisville School of Medicine, Louisville, Kentucky. He was also a Distinguished University Scholar. He joined University of Louisville in 1972 and rose through the ranks to become full Professor with tenure in 1979.

Research Interest

His research interest includes: Basic and translational research on nongonadal LH/hCG actions.

Scientific Activities

MEMBERSHIP IN PROFESSIONAL SOCIETIES

• American Society for Biochemistry and Molecular Biology
• American Society for Cell Biology
• American Physiological Society
• The Endocrine Society
• Society for Gynecologic Investigation
• Society for the Study of Reproduction
• American Society for Reproductive Medicine
• International Federation of Fertility Societies
• American Association for the Advancement of Science
• Sigma Xi
• International Federation of Placenta Associations
• International Society for the Study of Trophoblastic Diseases
• Life member of Indian Society for the Study of Reproduction and Fertility

AWARD:

• University of Louisville
• President’s Award for Outstanding Scholarship
• Research and Creative Activity, 1988

SPECIAL HONORS:

• Distinguished University Scholar, University of Louisville, 1998
• Medical Research Council’s Distinguished Visiting Scientist at the University of Cape Town, South Africa, 2005
• Professor Kesho Ram Laumas Memorial Oration-2007, Award given by All India Institute of Medical Sciences, New Delhi, to National/international scientist for outstanding contribution to the field of Reproductive Biology and Population Control
• 2009 Outstanding Alumnus Award from the Animal Science Department at the Washington State University, Pullman, Washington
• Guest of Honour at the International Conference on Multidisciplinary Approaches to Diabetes Research & Health, Jaipur, Rajasthan, India, November 14-16, 2010
• Professor L.S.Ramaswami Memorial Oration during 22nd Annual Meeting of the Indian Society for the Study of Reproduction and Fertility and ICMR Centenary Celebrations, New Delhi, India, February 19th 2012
• Visiting Professor at University of Rome Tor Vergata, March 31-April 4, 2014

Publications

FULL LENGTH PEER REVIEWED PUBLICATIONS

1. Rao ChV, Saxena BB. Gonadotropin receptors in the plasma membranes of rat luteal cells. Biochim Biophys Acta. 1973; 313: 372-389. doi: 10.1016/0304-4165(73)90037-8
2. Rao ChV, Saxena BB. Localization and preliminary characterization of the hCG receptor in the luteal cells. Acta Physiologica Latinoamericana. 1973; 23: 240-242.
3. Rao ChV, Carman F Jr. Stimulation of ovarian cyclic guanosine 3: 5-monophosphate levels by the subunits of human chorionic gonadotropin. Biochem Biophys Res Comm. 1973; 54: 744-750. doi: 10.1016/0006-291X(73)91486-1
4. Rao ChV. Receptors for prostaglandins and gonadotropins in cell membranes of bovine corpus luteum. Prostaglandins. 1973; 4: 567-576. doi: 10.1016/S0090-6980(73)80013-9
5. Rao ChV. Properties of gonadotropin receptors in the cell membranes of bovine corpus luteum. J Biol Chem. 1974; 249: 2864-2872.
6. Rao ChV. Prostaglandin receptors in the bovine corpus luteum cell membranes. Prostaglandins. 1974 6: 533-536. doi: 10.1016/0005-2736(76)90228-5
7. Rao ChV. Differential properties of prostaglandin and gonadotropin receptors in the bovine corpus luteum cell membranes. Prostaglandins. 1974; 6: 313-328.
8. Rao ChV. Differences between in vivo and in vitro actions of prostaglandins in corpus luteum tissue: is there a paradox? Prostaglandins. 1974; 7: 209-213.doi: 10.1007/BF00319035
9. Rao ChV. Characterization of prostaglandin receptors in the bovine corpus luteum cell membranes. J Biol Chem. 1974; 249: 7203-7209.
10. Rao ChV. Steroid hormone modulation of 3H-prostaglandin EI binding to bovine corpus luteum cell membranes. Prostaglandins. 1975; 9: 569-578.
11. Rao ChV. Mechanism of nucleotide inhibition of gonadotropin binding to bovine corpus luteum cell membranes. Mol Cell Endocrinol. 1975; 3: 255-271.
12. Rao ChV. Comparisons of affinity constants for PGEs receptor interaction with concentrations of PGEs needed for half maximal stimulation of adenylate cyclase. Prostaglandins. 1975; 9: 579-584.
13. Rao ChV. The presence of discrete receptors for prostaglandin F2 in the cell membranes of bovine corpora lutea. Biochem Biophys Res Comm. 1975; 64: 416-424.
14. Rao ChV. The presence of gonadotropin and prostaglandin E receptors in the cell membranes of bovine corpora lutea throughout pregnancy. Fertil Steril. 1975; 26: 1185-1189.
15. Rao ChV. Cationic dependency of high affinity prostaglandin F2receptors in bovine corpus luteum cell membranes. Biochem Biophys Res Comm. 1975; 67: 1242-1250. doi: 10.1016/0006-291X(75)90806-2
16. Rao ChV. Prostaglandin F2receptors in bovine corpus luteum cell membranes: effect of enzymes and protein reagents. Biochem Biophys Acta. 1976; 436: 170-182.
17. Rao ChV. Lack of negative cooperativity among binding sites for prostaglandin F2 in bovine corpus luteum cell membranes. Life Sci. 1976; 18: 499-506. doi: 10.1016/0024-3205(76)90327-1
18. Rao ChV. Prostaglandin F receptors in the cell membranes of bovine corpora lutea throughout pregnancy. Biol Reprod. 1976; 15: 134-139.
19. Rao ChV. Inhibition of 3H-prostaglandin F2 binding to its receptors by progesterone. Steroids. 1976; 27: 831-843.
20. Rao ChV. Properties of prostaglandin F2 receptors in bovine corpus luteum cell membranes. Mol Cell Endocrinol. 1976; 6: 1-16.
21. Rao ChV, Griffin LP, Carman FR Jr. Gonadotropin receptors in human corpora lutea of menstrual cycle and pregnancy. Amer J Obstet Gynecol. 1977; 128: 146-153.
22. Rao ChV, Griffin LP, Carman FR Jr. Gonadotropin receptors in human corpora lutea of menstrual cycle and pregnancy. J Clin Endocrinol Metab. 1977; 44: 1032-1037.
23. Rao ChV. Differential effects of detergents and dimethyl sulfoxide on membrane prostaglandin E I and F2 receptors. Life Sci. 1977; 20: 2013-2022.
24. Rao ChV, Mitra S. Subcellular distribution of prostaglandin and gonadotropin receptors in bovine corpora lutea. Biochem Biophys Res Comm. 1977; 76: 636-643. dio:10.1016/0006-291X(77)91548-0
25. Lin MT, Rao ChV. 3H-prostaglandins binding to dispersed bovine luteal cells: evidence for discrete prostaglandin receptors. Biochem Biophys Res Comm. 1977; 78: 510-516.
26. Mitra S, Rao ChV. Receptors for gonadotropins and prostaglandins in lysosomes of bovine corpora lutea. Arch Biochem Biophys. 1978; 185: 126-133.
27. Rao ChV. Effect of hydrolytic enzymes and protein modifying reagents on gonadotropin receptors in bovine corpus luteum cell membranes. Biochim Biophys Acta. 1978; 538: 212-225.
28. Lin MT, Rao ChV. Properties of 3H-prostaglandin F2 binding to dispersed bovine luteal cells. Life Sci. 1978; 22: 303-312.
29. Lin MT, Rao ChV. Selected properties of 3H-prostaglandin EI binding to dispersed bovine luteal cells. Mol Cell Endocrinol. 1978; 9: 311-320.
30. Rao ChV, Sanfilippo J, Carman FR Jr. Gonadotropin receptors in human corpora lutea of term pregnancies. Amer J Obstet Gynecol. 1978; 132: 581-583.
31. Mitra S, Rao ChV. Gonadotropin and prostaglandin binding sites in rough endoplasmic reticulum and golgi fractions of bovine corpora lutea. Arch Biochem Biophys. 1978; 191: 331-340.
32. Rao ChV, Carman FR Jr, Gorman RR. Prostaglandin E and F2 receptors in bovine corpora lutea: Relative affinities of products of arachidonic acid metabolism by cyclo-oxygenase. Biochem Biophys Res Comm. 1978; 85: 125-130.
33. Rao ChV, Harker CW. Prostaglandin E and F2receptors in bovine corpus luteum plasma membranes are two different macromolecular entities. Biochem Biophys Res Comm. 1978; 85: 1054-1060.
34. Rao ChV, Mitra S. Gonadotropin and prostaglandins binding sites in nuclei of bovine corpora lutea. Biochim Biophys Acta. 1979; 584: 454-466.
35. Rao ChV. Differential properties of human chorionic gonadotropin and human luteinizing hormone binding to plasma membranes of bovine corpora lutea. Acta Endocrinol. 1979; 90: 696-710.
36. Rao ChV, Estergreen VL, Carman FR Jr, Moss GE. Receptors for gonadotropins and prostaglandin F2 in bovine corpora lutea of early, mid and late luteal phase. Acta Endocrinol. 1979; 91: 529-537.
37. Lin MT, Rao ChV. Ornithine decarboxylase in bovine corpora lutea. J Endocrinol Invest. 1980; 3: 131-136.
38. Rao ChV, Willcourt R, Queenan JT. Lack of subhourly variations in plasma unconjugated estriol levels in pregnant diabetics in the third trimester. Amer J Obstet Gynecol. 1980; 137: 543-546.
39. Rao ChV. Pregnancy tests for office and home. Contemporary Ob/Gyn. 1980; 16: 107-112.
40. Mitra S, Rao ChV, Fields MJ. Enzyme activities in early, mid and late luteal phase bovine corpora lutea. Biochem Biophys Res Comm. 1980; 97: 1555-1561.
41. Rao ChV, Kable WT, Yussman MA, Mitra SB. Gonadotropin binding sites in ovaries of patients with familial XY gonadal dysgenesis and Turners syndrome. Letter to Editor. Amer J Obstet Gynecol. 1981; 139: 226.
42. Rao ChV, Mitra S, Carman FR Jr. Characterization of gonadotropin binding sites in the intracellular organelles of bovine corpora lutea and comparison with those in plasma membranes. J Biol Chem. 1981; 256: 2628-2634.
43. Rao ChV, Mitra S, Sanfilippo J, Carman FR Jr. The presence of gonadotropin binding sites in the intracellular organelles of human ovaries. Amer J Obstet Gynecol. 1981; 139: 655-660.
44. Cole LA, Hussa RO, Rao ChV. Discordant synthesis and secretion of human chorionic gonadotropin and subunits by cervical carcinoma cells. Cancer Res. 1981; 41: 1615-1619.
45. Andersen NH, Imamoto S, Subramanian N, et al() Molecular basis for prostaglandin potency. III. Tests of the significance of the hairpin conformation in biorecognition phenomena. Prostaglandins. 1981; 22: 841-856.
46. Andersen NH, Subramanian N, De B, McCrae DA, Tynan SS, Rao ChV. Methyl esters of prostaglandin F2 and I2. Prostaglandins and Medicine. 1981; 6: 345-357.
47. Rao ChV. Pregnancy tests for office and home. Ortho Forum. 1981; 1: 10-13.
48. Rao ChV, Hussa RO. A simple way to determine non-specific effects of plasma and serum components in radio receptor assays and radioimmune assays for human chorionic gonadotropin. Amer J Obstet Gynecol. 1982; 142: 153-158.
49. Rao ChV, Fields MJ, Chen TT, Abel JH Jr, Edgerton LA. Changes in gonadotropin binding sites in intracellular organelles and plasma membrane during luteal growth, development and regression. Exp Cell Res. 1983; 144: 285-295.
50. Rao ChV, Hussa RO, Carman FR Jr, Rinkle ML, Cook CL, Yussman MA. Stability of human chorionic gonadotropin and its alpha subunit in human blood. Amer J Obstet Gynecol. 1983; 146: 65-68.
51. Cook CL, Rao ChV, Yussman MA. Plasma gonadotropin and sex steroid hormone levels during early, mid follicular and mid luteal phases of women with luteal phase defects. Fertil Steril. 1983; 40: 45-48.
52. Hofmann GE, Rao ChV, Barrows GH, Sanfilippo JS. Topography of human uterine prostaglandin E and F2receptors and their profiles during pathological states. J Clin Endocrinol Metab. 1983; 57: 360-366. doi: http://dx.doi.org/10.1210/jcem-57-2-360
53. Rao ChV, Edgerton LA. Dissimilarity of corpora lutea within the same ovaries of those from right and left ovaries of pigs during the oestrus cycle. J Reprod Fertil. 1984; 70: 61-66.
54. Hofmann GE, Rao ChV, Barrows GH, Rossano LT, Sanfilippo JS. Prostaglandin E and F2 receptors in human uterine leiomyomas. J Clin Endocrinol Metab. 1984; 58: 454-457.
55. Rao ChV, Ireland JJ, Roche JF. Decrease of various luteal enzyme activities during prostaglandin F2 induced luteal regression in bovine. Mol Cell Endocrinol. 1984; 34: 99-103.
56. Chegini N, Rao ChV, Carman FR Jr. Internalization of 125I-human choriogonadotropin in luteal slices. A biochemical study. Exp Cell Res. 1984; 151: 466-482.
57. Chegini N, Rao ChV, Cobbs G. A quantitative electron microscope autoradiographic study on 125I-human choriogonadotropin internalization in bovine luteal slices. Exp Cell Res. 1984; 151: 483-493.
58. Hofmann GE, Rao ChV, Barrows GH, Schultz GS, Sanfilippo JS. Binding sites for epidermal growth factor in human uterine tissues and leiomyomas. J Clin Endocrinol Metab. 1984; 58: 880-884.
59. Rao ChV, Carman FR Jr, Chegini N, Schultz GS. Binding sites for epidermal growth factor in human fetal membranes. J Clin Endocrinol Metab. 1984; 58: 1034-1042.
60. Chegini N, Ramani N, Rao ChV. Morphological and biochemical characterization of small and large bovine luteal cells during pregnancy. Mol Cell Endocrinol. 1984; 37: 89-102.
61. Chegini N, Rao ChV, Cobbs G. A quantitative electron microscope autoradiographic study on 3H-prostaglandin E1 and F2 internalization in bovine luteal slices. Mol Cell Endocrinol. 1984; 38: 117-129.
62. Hofmann GE, Rao ChV, DeLeon FD, Toledo AA, Sanfilippo JS. Human endometrial prostaglandin E2 receptors and their profiles during the menstrual cycle and pathological states. Amer J Obstet Gynecol. 1985; 151: 369-375.
63. Rao ChV, Ramani N, Chegini N, Stadig B, Carman FR Jr, Woost P, Schultz G, Cook CL. Topography of human placental binding sites for epidermal growth factor. J Biol Chem. 1985; 260: 1705-1710.
64. Chegini N, Rao ChV. Epidermal growth factor binding to human amnion, chorion, decidua and placenta from mid and term pregnancy. Quantitative light microscope autoradiographic studies. J Clin Endocrinol Metab. 1985; 61: 529-535.
65. Chegini N, Rao ChV, Wakim N, Sanfilippo J. Prostaglandin binding to different cell types of human uterus: Quantitative light microscope autoradiographic study. Prostaglandins, Leukotrienes and Medicine. 1986; 22: 129-138.
DeLeon FD, Vijayakumar R, Brown M, Rao ChV, Yussman MA, Schultz G. Peritoneal fluid volume, estrogen, progesterone, prostaglandin and epidermal growth factor concentrations in patients with and without endometriosis. Obstet Gynecol. 1986; 68: 189-194.
66. Ramani N, Chegini N, Rao ChV, Woost P, Schultz G. The presence of epidermal growth factor binding sites in the intracellular organelles of term human placenta. J Cell Sci. 1986; 84: 19-40.
67. Chegini N, Rao ChV. Quantitative electron microscope autoradiographic studies on 125I-epidermal growth factor internalization in term human placenta. J Cell Sci. 1986; 84: 41-52.
68. Chegini N, Rao ChV, Wakim N, Sanfilippo J. Binding of 125I-epidermal growth factor to human uterus. Cell and Tissue Res. 1986; 246: 543-548.
69. Rao ChV, Carman FR Jr.The nature of reversible and not readily reversible bovine corpus luteum plasma membrane bound human chorionic gonadotropin. J Endocrinol Invest. 1986; 9: 403-406.
70. Wolfe WM, Rao ChV, McCracken EM, Demers LM, Huang KC, Tsueda K. Peripheral plasma levels of prostaglandin metabolites, cortisol and prolactin in women undergoing falope ring application and tubal cautery. Prostaglandins, Leukortrienes and Medicine. 1986; 25: 31-38.
71. Patsner B, Day TG, Rao ChV. Potential usefulness of monoclonal antibodies in invasive ovarian adenocarcinoma. J KY Med Assoc. 1986; 84: 613-615.
72. Chegini N, Rao ChV. A histochemical demonstration of 3- hydroxy steroid dehydrogenase in cells of human amnion, chorion, decidua and placenta from mid and term pregnancy. IRCS Med Sci. 1986; 14: 978-979.
73. Wakim NG, Ramani N, Rao ChV. Triiodothyronine receptors in porcine granulosa cells. Amer J Obstet Gynecol. 1987; 156: 237-240.
74. Ramani N, Rao ChV () Direct stimulation of nucleoside triphosphatase activity in bovine luteal nuclear membranes by human chorionic gonadotropin. Endocrinology. 1987; 120: 2468-2473.
75. Wolfe WM, Rao ChV, McCracken EM, Demers LM. Peripheral prostaglandin metabolite levels in women undergoing therapeutic abortions in the first trimester with and without treatment with prostaglandin synthetase inhibitor. Prostaglandins, Leukotrienes and Medicine. 1987; 28: 53-59.
76. Toledo A, Ramani N, Rao ChV. Direct stimulation of nucleoside triphosphatase activity in human ovarian nuclear membranes by human chorionic gonadotropin. J Clin Endocrinol Metab. 1987; 65: 305-309.
77. Chegini N, Rao ChV. Dynamics of nuclear associated granules in bovine luteal cells following treatment in vitro with prostaglandin F2. Endocrinology. 1987; 121: 1870-1878.
78. DeLeon FD, Vijayakumar R, Rao ChV, Yussman MA. Prostaglandin F2and E2 Release by peritoneum with and without endometriosis. Int J Fertil. 1988; 33: 48-51.
79. Chegini N, Rao ChV. The presence of leukotriene C4 and prostacyclin binding sites in nonpregnant human uterine tissue. J Clin Endocrinol Metab. 1988; 66: 76-87.
80. Hofmann GE, Rao ChV, Brown MJ, Murray LF, Schultz GS, Siddiqi TA. Human epidermal growth factor concentrations in urine of nonpregnant and pregnant women throughout pregnancy and at delivery. J Clin Endocrinol Metab. 1988; 66: 119-123.
81. Williams RS, Rao ChV, Yussman MA. Interference in the measurement of CA-125 in peritoneal fluid. Fertil Steril. 1988; 49: 547-550.
82. Chegini N, Rao ChV. Increase of nuclear bodies in bovine luteal cells following treatment with human chorionic gonadotropin. Biol Reprod. 1988; 38: 453-461.
83. Chegini N, Rao ChV. Quantitative light microscope autoradiographic study on (3H)-leukotriene C4 binding to nonpregnant bovine uterine tissue. Endocrinology. 1988; 122: 1732-1736.
84. Hofmann GE, Rao ChV, Carman FR Jr, Siddiqi TA. 125I-human epidermal growth factor specific binding to placentas and fetal membranes from various pregnancy states. Acta Endocrinol. 1988; 117: 485-490.
85. Chegini N, Rao ChV. The presence of leukotriene C4 binding sites in bovine corpora lutea of pregnancy. Biol Reprod. 1988; 39: 929-935.
86. Chegini N, Rao ChV. The presence of prostacyclin binding sites in nonpregnant bovine uterine tissue. Prostaglandins Leukotrienes and Essential Fatty Acids. 1989; 38: 75-79.
87. Oechsli M, Rao ChV, Chegini N. Human chorionic gonadotropin increases chromatin solubility in isolated bovine and human luteal nuclei. Biol Reprod. 1989; 41: 753-760.
88. Reshef E, Lei ZM, Rao ChV, Pridham DD, Chegini N, Luborsky JL. The presence of gonadotropin receptors in nonpregnant human uterus, human placenta, fetal membranes and decidua. J Clin Endocrinol Metab. 1990; 70: 421-430.
89. Pridham D, Lei ZM, Chegini N, Rao ChV, Yussman MA, Cook CL. Light and electron microscope immunocytochemical localization of 5-and 12-lipoxygenase and cyclooxygenase enzymes in human granulosa cells from preovulatory follicles. Prostaglandins Leukotrienes and Essential Fatty Acids. 1990; 39: 231-238.
90. Chegini N, Lei ZM, Rao ChV. Cellular distribution of prostacyclin synthase and specific prostacyclin binding sites in bovine corpora lutea of pregnancy. Mol Cell Endocrinol. 1990; 70: 133-140.
91. Rao ChV, Yussman MA, Hussa RO. Stability of human chorionic gonadotropin and its -subunit. Amer J Obstet Gynecol. 1990; 163: 1098-1099.
92. Rao ChV, Reshef E, Lei ZM. Gonadotropin receptors in nongonadal reproductive tissues. Assisted Reproductive Technology/Andrology. 1990; 1: 241-253.
93. Chegini N, Lei ZM, Rao ChV, Bischof P. The presence of pregnancy associated plasma protein-A in human corpora lutea: cellular and subcellular distribution and dependence on reproductive state. Biol Reprod. 1991; 44: 201-206.
94. Mitchell DE, Lei ZM, Rao ChV. The enzymes in cyclooxygenase and lipoxygenase pathways of arachidonic acid metabolism in human corpora lutea: dependence on luteal phase, cellular and subcellular distribution. Prostaglandins Leukotrienes and Essential Fatty Acids. 1991; 43: 1-12.
95. Stoelk E, Chegini N, Rao ChV, Bryant-Greenwood G, Sanfilippo J. Immunocytochemical localization of relaxin in human corpora lutea: cellular and subcellular distribution and dependence on reproductive state. Biol Reprod. 1991; 44: 1140-1147.
96. Lei ZM, Chegini N, Rao ChV. Quantitative cell composition of human and bovine corpora lutea from various reproductive states. Biol Reprod. 1991; 44: 1148-1156.
97. Chegini N, Lei ZM, Rao ChV. Nuclear volume and chromatin conformation of small and large bovine luteal cells: effect of gonadotropins and prostaglandins and dependence on luteal phase. Cell Tissue Res. 1991; 264: 453-460.
98. Bibbins PE Jr, Rao ChV, Carman FR, Chegini N, Lei ZM. Role of luteal cell nucleus in the expression of gonadotropin action. J Endocrinol Invest. 1991; 14: 391-400.
99. Chegini N, Lei ZM, Rao ChV, Hansel W. Cellular distribution and cycle phase dependency of gonadotropin and eicosanoids binding sites in bovine corpora lutea. Biol Reprod. 1991; 45: 506-513.
100. Lei ZM, Rao ChV. The expression of 15-lipoxygenase gene and the presence of functional enzyme in cytoplasm and nuclei of pregnancy human myometria. Endocrinology. 1992; 130: 861-870.
101. Indrapichate K, Meehan D, Lane TA, et al. Biological actions of monoclonal LH/hCG receptor antibodies. Biol Reprod. 1992; 46: 265-278.
102. Lei ZM, Rao ChV, Ackerman DM, Day TG. The expression of human chorionic gonadotropin/human luteinizing hormone receptors in human gestational trophoblastic neoplasms. J Clin Endocrinol Metab. 1992; 74: 1236-1241.
103. Swanson ML, Lei ZM, Swanson PH, Rao ChV, Narumiya S, Hirata M. The expression of thromboxane A2 synthase and thromboxane A2 receptor gene in human uterus. Biol Reprod. 1992; 47: 105-117.
104. Lei ZM, Rao ChV, Chakraborty C. Expression of thromboxane A2 receptor gene and thromboxane A2 synthase in bovine corpora lutea. Biol Reprod. 1992; 47: 233-244.
105. Lei ZM, Rao ChV. Expression of epidermal growth factor (EGF) receptor and its ligands, EGF and transforming growth factor-, in human fallopian tubes. Endocrinology. 1992; 131: 947-957.
106. Lei ZM, Reshef E, Rao ChV. The expression of human chorionic gonadotropin/luteinizing hormone receptors in human endometrial and myometrial blood vessels. J Clin Endocrinol Metab. 1992; 75: 651-659.
107. Lincoln S, Lei ZM, Rao ChV, Yussman MA. The expression of human chorionic gonadotropin/human luteinizing hormone receptors in ectopic human endometrial implants. J Clin Endocrinol Metab. 1992; 75: 1140-1144.
108. Lei ZM, Rao ChV. Gonadotropin receptors in human fetoplacental unit: Implications for hCG as an intracrine, paracrine and endocrine regulator of human fetoplacental function. Trophoblast Res. 1992; 6: 213-224 .
109. Shi QJ, Lei ZM, Rao ChV, Lin J. Novel role of human chorionic gonadotropin in differentiation of human cytotrophoblasts. Endocrinology. 1992; 132: 1387-1395.
110. Lei ZM, Rao ChV, Lincoln S, Ackermann DM. Increased expression of human chorionic gonadotropin/human luteinizing hormone receptors in adenomyosis. J Clin Endocrinol Metab. 1992; 76: 763-768.
111. Lei ZM, Rao ChV, Kornyei JL, Licht P, Hiatt ES. Novel expression of human chorionic gonadotropin/luteinizing hormone receptor gene in brain. Endocrinology. 132: 2262-2270. 112. Sanfilippo JS, Blotcky AJ, Rao ChV. Selenium in peritoneal fluid. J Reprod Med . 1992; 38: 422-126.
113. Toth P, Rao ChV. Direct novel regulation of cyclooxygenase and prostacyclin synthase by human chorionic gonadotropin in the human amnion. Trophoblast Res. 1992; 8: 503-514. 114. Bolli JAN, Doering DL, Bosscher JR, Day Jr TG, Rao ChV, Owens K, Kelly B, Goldsmith J. Squamous cell carcinoma antigen: clinical utility in squamous cell carcinoma of the uterine cervix. Gyn Oncol. 1994; 55: 169-173.
115. Lin J, Lei ZM, Lojun S, Rao ChV, Satyaswaroop PG, Day Jr TG. Increased expression of luteinizing hormone/human chorionic gonadotropin receptor gene in human endometrial carcinomas. J Clin Endocrinol Metab. 1994; 79: 1483-1491. doi: http://dx.doi.org/10.1210/jcem.76.3.7680356
116. Eta E, Ambrus G, Rao ChV. Direct regulation of human myometrial contractions by human chorionic gonadotropin. J Clin Endocrinol Metab. 1994; 79: 1582-1586. doi: http://dx.doi.org/10.1210/jcem.79.6.7989459
117. Ambrus G, Rao ChV. Novel regulation of pregnant human myometrial smooth muscle cell gap junctions by human chorionic gonadotropin. Endocrinology. 1994; 135: 2772-2779.
118. Rao ChV, Li X, Toth P, Lei ZM. Expression of epidermal growth factor, transforming growth factor alpha and their common receptor and its functional relevance to eicosanoid biosynthetic pathway in human umbilical cords. J Clin Endocrinol Metab. 80: 1012-1020.
119. Lukacs H, Hiatt ES, Lei ZM, Rao ChV. Peripheral and intracerebroventricular administration of human chorionic gonadotropin alters several hippocampus associated behaviors in cycling female rats. Hormones and Behavior. 1995; 29: 42-58.
120. Komatsu T, Konishi I, Mandai M, et al. Peritoneal serious papillary carcinoma arising in an infertile woman during ovulation-induction therapy: immunohistochemical expression of LH/hCG receptors. Gynecol Oncol. 1995; 56: 470-474.
121. Lei ZM, Rao ChV. Signaling and transacting factors in the transcriptional inhibition of gonadotropin releasing hormone gene by human chorionic gonadotropin in immortalized hypothalamic GT1-7 neurons. Mol Cell Endocrinol. 1995; 109: 151-157.
122. Cao H, Lei ZM, Bian L, Rao ChV. Functional nuclear epidermal growth factor receptors in human choriocarcinoma JEG-3 cells and normal human placenta. Endocrinology. 1995; 136: 3163-3172.
123. Cao H, Lei ZM, Rao ChV. Consequences of antisense human chorionic gonadotropin-subunit cDNA expression in human choriocarcinoma JAR cells. J Mol Endocrinol. 1995; 14: 337-347.
124. Lin J, Lojun S, Lei ZM, Wu WX, Peiper SC, Rao ChV. Lymphocytes from pregnant women express human chorionic gonadotropin / luteinizing hormone receptor gene. Mol Cell Endocrinol. 1995; 111: R13-R17.
125. Tao YX, Lei ZM, Woodworth SH, Rao ChV. Novel expression of luteinizing hormone/chorionic gonadotropin receptor gene in rat prostates. Mol Cell Endocrinol. 1995; 111: R9-R12.
126. Tao Y-X, Lei ZM, Hofmann GE, Rao ChV. Human intermediate trophoblasts express chorionic gonadotropin / luteinizing hormone receptor gene. Biol Reprod. 1995; 53: 899-904.
127. Singh M, Zuo J, Li X, Ambrus G, Lei ZM, Yussman MA, Sanfilippo JS, Rao ChV. The decreased expression of functional human chorionic gonadotropin/luteinizing hormone receptor gene in human uterine leiomyomas. Biol Reprod. 1995; 53: 591-597.
128. Kornyei J, Li X, Lei ZM, Rao ChV. Analysis of epidermal growth factor action in human myometrial smooth muscle cells. J Endocrinol. 1995; 146: 261-270.
129. Huang ZH, Lei ZM, Rao ChV. Immortalized anterior pituitary T3 gonadotropes contain functional luteinizing hormone/human chorionic gonadotropin receptors. Mol Cell Endocrinol. 1995; 114: 217-222.
130. Rodway MR, Rao ChV. A novel perspective on the role of human chorionic gonadotropin during pregnancy and in gestational trophoblastic disease. Early Pregnancy: Biology and Medicine. 1995; 1: 176-187.
131. How H, Huang ZH, Zuo J, Lei ZM, Spinnato II JA, Rao ChV. Myometrial estradiol and progesterone receptor changes in preterm and term pregnancies. Obstet Gynecol. 1995; 86: 936-940.
132. Hill JB, Jiminez AL, Passmore JC, Rao ChV. Effect of human chorionic gonadotropin on reproductive organ blood flow in cycling rats. Proc Soc Exptl Biol Med. 1996; 211: 94-99.
133. Toth P, Li X, Lei ZM, Rao ChV. Expression of human chorionic gonadotropin (hCG) / luteinizing hormone (LH) receptors and regulation of cyclooxygenase-1 gene by exogenous hCG in human fetal membranes. J Clin Endocrinol Metab. 1996; 81: 1283-1288.
134. Li X, Lei ZM, Rao ChV. Human chorionic gonadotropin down-regulates the expression of gonadotropin releasing hormone receptor gene in GT1-7 neurons. Endocrinology. 1996; 137: 899-904.
135. Kornyei JL, Li X, Lei ZM, Rao ChV. Restoration of human chorionic gonadotropin response in human myometrial smooth muscle cells by treatment with follicle stimulating hormone (FSH): Evidence for the presence of FSH receptors in human myometrium. Eur J Endocrinol. 1996; 134: 225-231.
136. Han SW, Lei ZM, Rao ChV. Up-regulation of cyclooxygenase-2 gene expression by chorionic gonadotropin during the differentiation of human endometrial stromal cells into decidua. Endocrinology. 1996; 137: 1791-1797.
137. Pabon JE, Li X, Lei ZM, Sanfilippo J, Yussman MA, Rao ChV. Novel presence of human luteinizing hormone/chorionic gonadotropin receptors in the human adrenal glands. J Clin Endocrinol Metab. 1996; 81: 2397-2400.
138. Han SW, Lei ZM, Rao ChV. Up-regulation of cyclooxygenase-2 gene expression by chorionic gonadotropin in mucosal cells from human fallopian tubes. Endocrinology. 1996; 137: 2929-2937. dio: http://dx.doi.org/10.1210/endo.137.7.8770916
139. Pabon JE, Bird JS, Li X, Huang Z-H, Lei ZM, Sanfilippo J, Yussman MA, Rao ChV. Human skin contains luteinizing hormone/chorionic gonadotropin receptors. J Clin Endocrinol Metab. 1996; 81: 2738-2741.
140. Hu Y, Lei ZM, Rao ChV. Cis-acting elements and trans-acting proteins in the transcription of chorionic gonadotropin/luteinizing hormone receptor gene in choriocarcinoma cells and placenta. Endocrinology. 1996; 137: 3897-3905.
141. Rao ChV. The beginning of a new era in reproductive biology and medicine: Expression of low levels of functional luteinizing hormone/human chorionic gonadotropin receptors in nongonadal tissues. J Physiol and Pharmacol. 1996; 47: 41-53.
142. Tao Y-X, Bao S, Ackermann DM, Lei ZM, Rao ChV. Expression of luteinizing hormone/human chorionic gonadotropin receptor gene in benign prostatic hyperplasia and in prostate carcinoma in humans. Biol Reprod. 56: 67-72.
143. Hill JB, Alsip NL, Rao ChV, Asher EF. Human chorionic gonadotropin directly and indirectly alters the uterine arteriolar diameters in cycling rats. Am J Obstet Gynecol. 1997; 176: 150-157.
144. AL-Hader AA, Lei ZM, Rao ChV. Novel expression of functional luteinizing hormone/chorionic gonadotropin receptors in cultured glial cells from neonatal rat brains. Biol Reprod. 1997; 56: 501-507.
145. Rao ChV, Sanfilippo JS. New understanding in the biochemistry of implantation: potential direct roles of luteinizing hormone and chorionic gonadotropin. Endocrinologist. 1997; 7: 107-111.
146. Tao Y-X, Lei ZM, Rao ChV. The presence of luteinizing hormone/ human chorionic gonadotropin receptors in lactating rat mammary glands. Life Sciences. 1997; 60: 1297-1303.
147. Rao ChV. Potential novel roles of luteinizing hormone and human chorionic gonadotropin during early pregnancy in women. Early Pregnancy: Biology and Medicine. 1997; 3: 1-9.
148. AL-Hader AA, Lei ZM, Rao ChV. Neurons from fetal rat brains contain functional luteinizing hormone/chorionic gonadotropin receptors. Biol Reprod. 1997; 56: 1071-1076.
149. Lei ZM, Rao ChV. Cis-acting elements and trans-acting proteins in the transcriptional inhibition of gonadotropin releasing hormone gene by human chorionic gonadotropin in immortalized hypothalamic GT1-7 neurons. J Biol Chem. 1997; 272: 14365-14371.
150. Han SW, Lei ZM, Rao ChV. Homologous down-regulation of luteinizing hormone/chorionic gonadotropin receptors by increasing the degradation of receptor transcripts in human uterine endometrial stromal cells. Biol Reprod. 1997; 57: 158-164. dio: 10.1095/biolreprod57.1.158
151. Konishi I, Koshiyama M, Mandai M, et al. Increased expression of LH/hCG receptors in endometrial hyperplasia and carcinoma in anovulatory women. Gynecol Oncol. 1997; 65: 273-280.
152. Huang Z-H, Lei ZM, Rao ChV. Novel independent and synergistic regulation of gonadotropin -subunit gene by luteinizing hormone/human chorionic gonadotropin and gonadotropin releasing hormone in the T3-1 gonadotrope cells. Mol Cell Endocrinol. 1997; 130: 23-31.
153. Sun T, Lei ZM, Rao ChV. A novel regulation of the oviductal glycoprotein gene expression by luteinizing hormone in bovine tubal epithelial cells. Mol Cell Endocrinol. 1997; 131: 97-108.
154. Rao ChV. Immunocytochemical localization of gonadotropin and gonadal steroids in human pineal glands. A letter to the editor. J Clin Endocrinol Metab. 1997; 82: 2756-2757.
155. Lojun S, Bao S, Lin J, Lei ZM, Rao ChV. The presence of functional luteinizing hormone/ chorionic gonadotropin (hCG) receptors in human breast cell lines: Implications supporting the premise that hCG protects women against breast cancer. Biol Reprod. 1997; 57: 1202-1210.
156. Mandai M, Konishi I, Kuroda H, Fukumoto M, Komatsu T, Yamamoto S, Nanbu K, Rao ChV, Mori T. Messenger ribonucleic acid expression of LH/hCG receptor gene in human ovarian carcinomas. Eur J Cancer. 1997; 33: 1501-1507.
157. Kuroda H, Konishi I, Nanbu K, Mandai M, Matsushita K, Hamid AA, Yura Y, Rao ChV, Mori T. Ovarian cancer in infertile women during or after ovulation-induction therapy; expression of LH/hCG receptors and sex steroid receptors. Intl J Gynecologic Cancer. 1997; 7: 451-457.
158. AL-Hader AA, Tao Y-X, Lei ZM, Rao ChV. Fetal rat brains contain luteinizing hormone/human chorionic gonadotropin receptors. Early Pregnancy: Biology and Medicine. 1997; 3: 323-329.
159. Topilko P, Schneider-Maunoury S, Levi G, Trembleau A, Gourdji D, Driancourt M-A, Rao ChV, Charnay P. Multiple pituitary and ovarian defects in Krox-24 (NGF1-A, Egr-1)-targeted mice. Mol Endocrinol 12: 107-122.
160. Bird J, Li X, Lei ZM, Sanfilippo J, Yussman MA, Rao ChV. Luteinizing hormone and human chorionic gonadotropin decrease type 2 5-reductase and androgen receptor protein levels in womens skin. J Clin Endocrinol Metab 83: 1776-1782.
161. Tao Y-X, Lei ZM, Rao ChV . Seminal vesicles are novel site of luteinizing hormone/human chorionic gonadotropin receptor gene expression. J Androl. 1998; 19: 343-347. dio: 10.1002/j.1939-4640.1998.tb02014.x
162. Bian L, Lei ZM, Rao ChV. Mitogen activated protein kinase is involved in epidermal growth factor regulated protein phosphorylation in nuclear membranes isolated from JEG-3 human choriocarcinoma cells. Eur J Biochem. 1998; 253: 545-551.
163. Thompson DA, Othman MI, Lei ZM, Li X, Huang ZH, Eadie DM, Rao ChV. Localization of the receptor for luteinizing hormone/chorionic gonadotropin in neural retina. Life Sci. 1998; 63: 1057-1064.
164. Hu YL, Lei ZM, Rao ChV. Analysis of the promoter of luteinizing hormone/human chorionic gonadotropin receptor gene in neuroendocrine cells. Life Sci. 1998; 63: 2157-2165.
165. Tao Y-X, Heit M, Lei ZM, Rao ChV. The urinary bladder of a woman is a novel site of luteinizing hormone-human chorionic gonadotropin receptor gene expression. Am J Obstet Gynecol. 1998; 179: 1026-1031.
166. Han SW, Lei ZM, Rao ChV. Treatment of human endometrial stromal cells with chorionic gonadotropin induces their morphological and functional differentiation into decidua. Mol Cell Endocrinol. 1999; 147: 7-16.
167. Skipor J, Bao S, Grzegorzewski W, Wsowska B, Krzymowski T, Rao ChV. The inhibitory effect of hCG on counter current transfer of GnRH and the presence of LH/hCG receptors in the perihypophysial cavernous sinus-carotid rete vascular complex of ewes. Theriogenology. 1999; 51: 899-910.
168. Hu YL, Lei ZM, Huang ZH, Rao ChV. Determinants of transcription of the chorionic gonadotropin/ luteinizing hormone receptor gene in human breast cells. The Breast J. 1999; 5: 186-193.
169. Kornyei JL, Vertes ZS, Oszter A, Kovacs KA, Rao ChV, Vertes M. Opioid peptides inhibit the action of oestradiol on human myometrial cells in culture. Mol Human Reprod. 1999; 5: 566-572.
170. Rao ChV . No mRNAs for the LH/hCG receptor in human endometrium? Letter to the Editor. Fertil Steril. 1999; 72: 374-375.
171. Rao ChV . A paradigm shift on the targets of luteinizing hormone/human chorionic gonadotropin actions in the body. The Journal of the Bellevue Obstetrical & Gynecological Society. 1999; XV: 26-32.
172. Zhou XL, Lei ZM, Rao ChV. Treatment of human endometrial gland epithelial cells with chorionic gonadotropin/luteinizing hormone increases the expression of cyclooxygenase-2 gene. J Clin Endocrinol Metab. 1999; 84: 3364-3377.
173. Zhang W, Lei ZM, Rao ChV. Immortalized hippocampal neurons contain functional luteinizing hormone/human chorionic gonadotropin receptors. Life Sci. 1999; 65: 2083-2098.
174. Kurtzman, JT, Spinnato JT, Goldsmith LJ, et al. Human chorionic gonadotropin exhibits potent inhibition of preterm delivery in a small animal model. Am J Obstet Gynecol. 1999; 181: 853-857.
175. Lei ZM, Taylor DD, Gercel-Taylor C, Rao ChV. Human chorionic gonadotropin promotes tumorigenesis of choriocarcinoma JAR cells. Trophoblast Res. 1999; 13: 147-159.
176. Jauniaux E, Bao S, Eblen A, Li X, Lei ZM, Meuris S, Rao ChV . Human chorionic gonadotropin concentration and receptor gene expression in placental tissue from trisomy 18 and 21. Mol Human Reprod. 2000; 6: 5-10.
177. Bugalho MJM, Li X, Rao ChV, Soares J, Sobrinho LG. Presence of a GS mutation in an adrenal tumor expressing LH/hCG receptors and clinically associated with Cushings syndrome. Gynecol Endocrinol. 2000; 14: 50-54.
178. Danikas D, Goudas VT, Rao ChV, Brief DK. Luteinizing hormone receptor expression in leiomyomatosis peritonealis disseminata. Obstet Gynecol. 2000; 95: 1009-1011.
179. Akerman FM, Lei ZM, Rao ChV, Nakajima ST. A case of spontaneous ovarian hyper-stimulation syndrome with a potential mutation in hCG/LH receptor gene. Fertil Steril. 2000; 74: 403-404.
180. Corley DR, Li X, Lei ZM, Rao ChV. Potential regulation of gonadotropin releasing hormone gene by steroidogenic factor-1-like protein. Mol Human Reprod. 2000; 6: 671-676. dio: 10.1093/molehr/6.8.671
181. Rao ChV . Does full-term pregnancy at young age protect women against breast cancer through hCG? Obstet Gynecol. 2000; 96: 783-786.
182. Lei ZM, Mishra S, Zou W, Xu B, Foltz M, Li X, Rao ChV . Targeted disruption of luteinizing hormone/human chorionic gonadotropin receptor gene. Mol Endocrinol. 2001; 15: 184-200
183. Rao ChV . An overview of the past, present and future of nongonadal LH/hCG actions in reproductive biology and medicine. Sem Reprod Med. 2001; 19: 7-17.
184. Kurtzman J, Wilson H, Rao ChV . A proposed role for hCG in clinical obstetrics. Sem Reprod Med. 2001; 19: 63-68.
185. Rao ChV, Alsip NL . Use of rat model to study hCG/LH effects on uterine blood flow. Sem Reprod Med. 2001; 19: 75-85.
186. Lei ZM, Rao ChV . Neural actions of luteinizing hormone and human chorionic gonadotropin. Sem Reprod Med. 2001; 19: 103-109.
187. Eblen A, Bao S, Lei ZM, Nakajima ST, Rao ChV . The presence of functional luteinizing hormone/chorionic gonadotropin receptors in human sperm. J Clin Endocrinol Metab. 2001; 86: 2643-2648.
188. Rao ChV . The role of hCG and cAMP/PKA signaling in the differentiation of human endometrial stromal cells. A letter to the editor, J Clin Endocrinol Metab. 2001; 86: 4000-4001.
189. Rao, ChV. Multiple novel roles in luteinizing hormone. Fertil Steril. 2001; 76: 1097-1100.
190. Toth P, Lukacs H, Gimes G, Sebestyen A, Pasztor N, Paulin F, Rao ChV . Clinical importance of vascular LH/hCG receptors – A review. Reprod Biol. 2001; 1: 5-11.
191. Rao CV, Lei ZM. Consequences of targeted inactivation of LH receptors. Mol Cell Endocrinol. 2002; 187: 57-67.
192. Albert C, Garrido N, Mercader A, Rao CV, Remohi J, Simon C, Pellicer A. The role of endothelial cells in the pathogenesis of ovarian hyperstimulation syndrome. Mol Human Reprod. 2002; 8: 409-418.
193. Rao ChV. Gonadotropins and the uterus. Is there a gonad – independent pathway. A letter to the editor. J Soc Gynecol Invest. 2002; 9: 181.
194. Akerman F, Lei ZM, Rao ChV. Human umbilical cord and fetal membranes co-express leptin and its receptor genes. Gynecol Endocrinol. 2002; 16: 299-306.
195. Wy LA, Carlson HE, Kane P, Li X, Lei ZM, Rao ChV . Pregnancy-associated Cushings syndrome secondary to an LH/hCG receptor-positive adrenal carcinoma. Gynecol Endocrinol. 2002; 16: 413-417.
196. Zygmunt M, Herr F, Keller-Schoenwetter S, Kunzi-Rapp K, Munstedt K, Rao ChV, Lang U, Preissner KT. Characterization of human chorionic gonadotropin as a novel angiogenic factor. J Clin Endocrinol Metab. 2002; 87: 5290-5296.
197. Bhatnagar KP, Li X, Lei ZM, Rao ChV. Human pineal luteinizing hormone receptors. Biotechnic & Histochem. 2002; 77: 223-228. 198. Rao CV. RecepteursalaLH : folliculeetendometre. J Gynecol Obstet Biol Reprod. 2002; 31: 1S7-1S11.
199. Goodarzi MO, Dawson D, Li X, Lei ZM, Shintaku P, Rao ChV, Van Herle AJ . Virilization in bilateral macronodular adrenal hyperplasia controlled by the luteinizing hormone receptor. J Clin Endocrinol Metab. 88: 73-77.
200. Rao SC, Li X, Rao ChV, Magnuson DSK . Human chorionic gonadotropin/luteinizing hormone receptor expression in the adult rodent spinal cord. Neurosci Lett. 2003; 336: 135-138.
201. Zhang YM, Rao ChV, Lei ZM. Macrophages in human reproductive tissues contain luteinizing hormone/chorionic gonadotropin receptors. Am J Reprod Immunol. 2003; 49: 93-100.
202. Lei ZM, Zou W, Mishra S, Li X, Rao ChV . Epididymal phenotype in LH receptor knockout animals and its responses to testosterone replacement therapy. Biol Reprod. 2003; 68: 888-895.
203. Yang M, Lei ZM, Rao ChV . The central role of human chorionic gonadotropin in the formation of human placental syncytium. Endocrinology. 2003; 144: 1108-1120.
204. Mishra S, Lei ZM, Rao ChV . A novel role of luteinizing hormone in the embryo development in cocultures. Biol Reprod. 2003; 68: 1455-1462.
205. Than NG, Itakura A, Rao ChV, Nohira T, Toth P, Mansell JP, Isaka K, Nishi H, Takayama M, Than GN . Clinical applications of pregnancy-related proteins – A Workshop Report. Trophoblast Research. 2003; 17: S60-S64.
206. Lin PC, Li X, Lei ZM, Rao ChV . Human cervix contains functional luteinizing hormone/ human chorionic gonadotropin receptors. J Clin Endocrinol Metab. 2003; 88: 3409-3414.
207. Abdallah MA, Lei ZM, Li X, Greenwold N, Nakajima ST, Jauniaux E, Rao ChV . Human fetal nongonadal tissues contain human chorionic gonadotropin/luteinizing hormone receptors. J Clin Endocrinol Metab. 2004; 89: 952-956.
208. Rao ChV, Li X, Manna SK, Lei ZM, Aggarwal BB . Human chorionic gonadotropin decreases proliferation and invasion of breast cancer MCF-7 cells by inhibiting NF-B and AP-1 activation. J Biol Chem. 2004; 279: 25503-25510.
209. Carlson HE, Kane P, Lei ZM, Li X, Rao ChV . Presence of luteinizing hormone/human chorionic gonadotropin receptors in male breast tissues. J Clin Endocrinol Metab. 2004; 89: 4119-4123.
210. Rao ChV, Zhou XL, Lei ZM . Functional luteinizing hormone/chorionic gonadotropin receptors in human adrenal cortical H295R cells. Biol Reprod. 2004; 71: 579-587.
211. LO KC, Lei ZM, Rao ChV, Lamb DJ . De novo testosterone production in luteinizing hormone receptor knockout mice after transplantation of Leydig stem cells. Endocrinology. 2004; 145: 4011-4015.
212. Baal N, Reisinger K, Jahr H, Bohle RM, Liang O, Munstedt K, Rao CV, Preissner KT, Zygmunt MT. Expression of transcriptional factor Oct-4 and other embryonic genes in CD133 positive cells from human umbilical cord blood. Throm Haemost. 2004; 92: 767-775. 213. Lei Z, Mishra S, Ponnuru P, Li X, Yang ZW, Rao ChV . Testicular phenotype in luteinizing hormone receptor knockout animals and the effect of testosterone replacement therapy. Biol Reprod. 2004; 71: 1605-1613. 214. Lin DX, Lei ZM, Li X, Rao ChV . Targeted disruption of LH receptor gene revealed the importance of uterine LH signaling. Mol Cell Endocrinol. 2005; 234: 105-116.
215. Than NG, Nagai A, Sharma S, Meiri H, Mouzon SH, Sadvosky Y, Rao ChV . Applications of pregnancy-related proteins in prenatal and tumor diagnostics – A workshop report. Trophoblast Res. 2005; 19: S110-S113.
216. Lin DX, Lei ZM, Rao ChV . Dependence of uterine cyclooxygenase-2 expression on luteinizing hormone signaling. Biol Reprod. 2005; 73: 256-260.
217. Filicori M, Fazleabas AT, Huhtaniemi IT, Licht P, Rao ChV, Tesarik J, Zygmunt M . Novel concepts of human chorionic gonadotropin reproductive system interactions and potential in the management of infertility. Fertil & Steril. 2005; 84: 275-284.
218. Soukhova-OHare G, Lei ZM, Falcone JC, Barati MT, Feitelson JBA, Rao ChV Fleming JT . Bone medullary arterioles from ovariectomized rats have smaller baseline diameters, but normal eNOS expression and NO – mediated dialation. Life Sci. 2005; 77: 1799-1812.
219. Chudgar D, Lei ZM, Rao ChV . Orthotopic transplantation of LH receptor knockout and wild-type ovaries. Life Sci. 2005; 77: 2656-2662.
220. Amigh KS, Mayhew BA, Montero F, Schiavi F, White PC, Rao ChV, Rainey WE . Elevated expression of luteinizing hormone receptor in aldosterone-producing adenomas. J Clin Endocrinol Metab. 2006; 91: 1136-1142.
221. Rao CV. Physiological and pathological relevance of human uterine LH/hCG receptors. J Soc Gynecol Invest. 2006; 13: 77-78.
222. Yuan FP, Lin DX, Rao ChV, Lei ZM . Crytorchidism in LH receptor knockout animals and the effect of testisterone replacement therapy. Hum Reprod. 2006; 21: 936-942.
223. Ticconi C, Belmonte A, Piccione E, Rao ChV . Feto-placental communication system with myometrium in pregnancy and parturition: the role of hormones, neurohormones, inflammatory mediators and locally active factors. J Matern Fetal Neonatal Med. 2006; 19: 125-133.
224. Ticconi C, Piccione E, Belmonte A, Rao, Ch V. HCG – A new kid on the block in the prematurity prevention. J Matern Fetal Neonatal Med. 2006; 19: 687-692.
225. Lei ZM, Yang M, Li X, Takikawa O, Rao ChV . Upregulation of placental indoleamine 2,3- dioxygenase by human chorionic gonadotropin. Biol Reprod. 2007; 76: 639-644.
226. Rao ChV, Lei ZM . The past, present and future of nongonadal LH/hCG actions in reproductive biology and medicine. Mol Cell Endocrinol. 2007; 269: 2-8.
227. Casadesus G, Milliken EL, Webber KM, Bowen RL, Lei ZM, Rao, CV, Atwood CS, Nilson JH, Perry G, Keri RA, Smith MA. Declines in cognitive performance are associated with increased luteinizing hormone levels in mice. Mol Cell Endocrinol. 2007; 269: 107-111.
228. Ticconi C, Zicari A, Belmonte A, Realacci M, Rao ChV, Piccione E. Pregnancy – promoting actions of hCG in human myometrium and fetal membranes. Placenta. 2007; 28: Supplement A, S137-S143.
229. Herrmann-Lavoie C, Rao CV, Akoum A. Chorionic gonadotropin downregulates the expression of the decoy inhibitory interleukin 1 receptor type 11 in human endometrial epithelial cells. Endocrinology. 2007; 148: 5377-5384.
230. Sukhova-O Hare GK, Shah ZA, Lei ZM, Nozdrachev AD, Rao CV, Gozal D. Erectile dysfunction in a murine model of sleep apnea. Am J Respir Crit Care Med. 2008; 178: 644- 650.
231. Rask E, Schvarcz E, Hellman P, Hennings J, Karlsson A, Rao CV. ACTH – independent Cushings syndrome in pregnancy related to overexpression of adrenal LH/hCG receptors. J Endocrinol Invest. 2009; 33: 313-316.
232. Rahman N, Rao CV. Recent progress in luteinizing hormone/human chorionic gonadotrophin hormone research. Mol Human Reprod. 2009; 15: 703-711.
233. Lin J, Li X, Yuan FP, Lin L, Rao CV, Cook CL, Lei ZM. Genetic ablation of luteinizing hormone receptor improves the amyloid pathology in a mouse model of Alzheimer disease. J Neuropathol Exp Neurol. 2010; 69: 253-261.
234. Yuan FP, Li X, Lin J, Schwabe C, Bullesbach EE, Rao CV, Lei ZM. The role of RXFP2 in mediating androgen-induced inguinoscrotal testis descent in LH receptor knockout mice. Reproduction. 2010; 139: 759-769.
235. Rao CV. Human adrenal LH/hCG receptors and what they could mean for adrenal physiology and pathology. Mol Cell Endocrinol. 2010; 329: 33-36.
236. Yu Y, Yuan FP, Li X, Lin D, Lan Z, Rao CV, Lei ZM. Luteinizing hormone receptor deficiency increases the susceptibility to alkylating agent- induced lymphomagenesis in mice. Hormones and Cancer. 2010; 5: 256-264.
237. Morris LF, Park S, Daskivich T, Churchill BM, Rao CV, Lei ZM, Martinez DS, Yeh MW. Virilization of female infant by a maternal adrenocortical carcinoma. Endocrine Practice. 2011; 17: e26-e31.
238. Bourdiec A, Shao R, Rao CV, Akoum A. Human chorionic gonadaotropin triggers angiogenesis via the modulation of endometrial stromal cell responsiveness to Interleukin-1. A new possible mechanism underlying implantation. Biol Reprod. 2012; 87: 1-10.
239. Bourdiec A, Bedard D, Rao CV, Akoum A. Human chorionic gonadotropin regulates endothelial cell responsiveness to interleukin 1 and amplifies the cytokine-mediated effect on cell proliferation,migration and release of angiofenic factors. Am J Reprod Immunol. 2013; 70: 127-138.
240. Bourdiec A, Calvo E, Rao CV, Akoum A. Transcriptome analysis reveals new insights into the modulation of endometrial stromal cell receptive phenotype by embryo-derived signals interleukin-1 and human chorionic gonadotropin. Possible involvement in early embryo implantation. PLoS One. 2013; 8: e64829, 1-18.
241. Rao CV. Uphill battle on the paradigm shift on the targets of human chorionic gonadotropin/luteinizing hormone actions. An editorial. Enliven: Gynecol Obstet. 2014; 1(1): e001.
242. Rao CV. Uphill battle: The saga of hCG research that led to paradigm shift. Ind J Med Res. 2014.
243. Rao CV, Ticconi C. Why does human chorionic gonadotropin have such a broad regulatory roles in the body and are they totally unexpected. J Reprod Health and Med. 2014.
244. Rao CV. Potential Therapy of HIV/AIDS and Ebola Outbreak with Pregnancy Hormone, Human Chorionic Gonadotropin. HIV/AIDS Res Treat Open J. 2014; 1(1): e5-e6.