Brian Birch, BA, MA, MB, BChir, FRCS (England), MD (Cantab)

Honorary Associate Professor Urology and Consultant Urologist
University Hospital Southampton NHS Foundation Trust – Division A
Surgery Care Group Managers Office
E-Level, West Wing, Mailpoint 67
Southampton General Hospital
Tremona Road, SO16 6YD, Southampton, UK

Biography

QUALIFICATIONS (Educational and Professional)

1976, BA Natural Sciences University of Cambridge
1980, MA Medicine University of Cambridge
1980, MB BChir Medicine and Surgery University of Cambridge
1985, FRCS (England) Surgery Royal College of Surgeons of England
1995, MD Surgery University of Cambridge

Research Interest

His research interests include: Prostate, cancer, Prostate, BPH, Bladder, dysfunction, neurogenic, inflammation, interstitial cystitis, Urinary tract infection, Sexual dysfunction, erectile dysfunction, Hypogonadism, testosterone, Pain, chronic pelvic

Scientific Activities

MAJOR HONOURS & DISTINCTIONS

Scholarship St Catharine’s College Cambridge University, 1973
First Class Honours Natural Sciences Tripos, 1976
First Prize Final FRCS Revision Course Royal College of Surgeons, 1985
McNeill Love Prize in Surgery Whittington and Royal Northern Hospitals, 1989
Everidge Research Prize in Urology King’s College Hospital, 1989
Clifford Morson Prize Institute of Urology, 1989
Best Paper Urological Research Society Meeting, 1990
Shackman Travelling Scholarship, 1990
British Urological Foundation Praeceptorship, 2008
Honorary Senior Lecturer, 2010
Honorary Associate Professor, 2015

Publications

Books – Short Works
• B R P Birch and R A Miller. Operative Endoscopic Surgery under Sedoanalgesia. Recent Advances in Urology and Andrology 5. Churchill Livingstone, 1992
• B R P Birch and R A Miller. Transurethral Prostatectomy under Local Anaesthesia. Blackwell Scientific Publications. 1996
• B R P Birch. The management of urinary calculi. Recent Advances in Surgery 20. Churchill Livingstone, 1997.
• B R P Birch and P. Ratan. The management of Benign Prostatic Hyperplasia. Recent Advances in Surgery 24 Churchill Livingstone

Journal Letters

• Safety of Midazolam. Birch, B R P and Miller, R A. Lancet 1988; 2: 683.
• Use of Hospital Beds. Birch, B R P, Anson K M, Clifford, E and Miller R A. British Medical Journal 1988; 297: 1404-1405 and British Medical Journal 1989; 298: 526.
• Hypotension and Neurological Sequelae Following Midazolam. Birch, B R P, Anson, K M and Miller, R A. Anaesthesia 1989; 44: 259.
• The Use of Stents For Treating Obstruction of Urinary Outflow in Patients Unfit for Surgery. Parker, C, Birch, B R P, Gelister, J, Grant, D and Miller, R A. British Medical Journal 1989; 299: 120.
• Dental Sedation. A Review. Birch, B R P and Rosenbaum, M. British Dental Journal 1989; 166: 111.
• Anaesthesia advance boosts Day-Case surgery. Birch, B R P, Miller, R A. and Anson, K M. Hospital Doctor 1989; C9 29: 28.
• Day-case methods break new ground. Birch, B R P, Anson, K M, Kalmanowitz, D V and Miller,R A Hospital Doctor 1989; C9 40: 12.
• Death after Flumazenil? Birch, B R P and Miller, R A. British Medical Journal 1990; 300: 467-468.
• Subcutaneous flumazenil and recovery from midazolam. Birch, B R P. British Journal of Anaesthesia 1990; 65: 292.
• Medical or Surgical orchidectomy. Birch, B R P. British Medical Journal 1991; 302: 1021-1022.

Journal Papers – Academic Journals

• Allergic Reaction to Intravesical Adriamycin. Birch, B R P and Crisp, J C. British Journal of Urology 1988; 61: 165 – 166.
• Tethered Ureteric Stents – A Clinical Assessment. Birch, B R P, Das, G and Wickham J E A. British Journal of Urology 1988; 62: 409 – 411.
• 1500 Cases of Renal and Ureteric Calculi Treated in an Integrated Stone Centre. Das, G, Dick, J, Baily, M, Fletcher, M S, Birch, B R P, Coptcoat, M J, Webb, D R, Kellet, M J, Whitfield, H N and Wickham, J E A. British Journal of Urology 1988; 62: 301-305.
• Rigid operative cystoscopy without general anaesthesia. Miller, R A, Parry, J, Coptcoat, M, Birch, B R P and Das, G.
Archives of Italian Urology 1988; LX: 265-271.
*Review article
• The pT1 G3 Bladder Tumour. Birch, B R P and Harland S J. British Journal of Urology 1989; 64: 109-116.
• Sedoanalgesia in Urology: Technique, Applications and Impact. Birch, B R P, Anson, K M, Gelister, J and Miller, R A. World Journal of
Urology 1989; 7: 162-165.
• Advances in Minimally Invasive Surgery of the Prostate. Miller, R A, Gelister, J, Lei, C, Parker, C, Anson, K M, Grant, D and Birch, B World Journal of Urology 1989; 7: 166-169.
• *An Electrode for Sensory Stimulation of the Bladder. Ison, K T and Birch, B R P. Medical & Biological Engineering & Computing 1989; 27: 636-637.
Review Article
• Percutaneous Nephrolithotomy. Birch, B R P and Miller, R A. Surgery 1989; 70: 1680-1683.
• The Impact of Minimally Invasive Surgery and Sedoanalgesia on Urological Practice. Miller, R A, Birch, B R P, Anson, K M, Bell, J, Gelister, J and Grant, D. Postgraduate Medical Journal 1990; 66 (Suppl 1): S72-S76.
• The Role of Midazolam and Flumazenil in Urology. Birch, B R P, Anson, K M, Gelister, J, Parker, C and Miller, R A.
ActaAnaesthesiolScand 1990; 34 (suppl 92): 25-32.
• Day Case Surgery – Enhanced Recovery with Flumazenil. Birch, B R P, Anson, K M, Clifford, E and Miller, R A. Journal of The Royal Society of Medicine 1990; 83: 436-438.
• *The differential effects of Flumazenil on the psychomotor and amnesic actions of Midazolam. Birch, B R P and Curran, H V. Journal of Psychopharmacology 1990; 4: 29-34.
• Sedoanalgesia: A Safe, Cost Effective Alternative to General Anaesthesia – A Review of 1,020 Cases. Birch, B R P, Anson, K M, Gelister, J and Miller, R A. British Journal of Urology 1990; 66: 342-350.
• External Biliary Fistula Uncomplicated by Gall Stones. Birch, B R P and Cox, S J. Postgraduate Medical Journal 1991; 67: 391-392.
• Sedation for day-case surgery: An assessment of patient recovery profiles following Midazolam and Flumazenil. Birch, B R P, Anson, K M, Kalmanovitch, D V, Cooper, J and Miller, R A. Annals of The Royal College of Surgeons of England 1991; 73: 373-378.
• Transurethral resection of the prostate under local anaesthesia and sedation (sedoanalgesia): Experience in 100 patients. Birch, B R P, Gelister, J S K, Parker, C J, Chave, H and Miller, R A. Urology 1991; 38: 113-118.
• The Birch-Miller electrotest needle: An aid to local anaesthetic endoscopic surgery. Birch, B R P and Miller, R A.
Urology. 1991; 38: 64-65.
• *Differentiating the sedative, psychomotor and amnesic effects of benzodiazepines: a study with midazolam and the benzodiazepine antagonist, flumazenil. Curran, H V and Birch, B R P. Psychopharmacology 1991; 103: 519-523.
• Evaluation of endothelial markers in detecting blood and lymphatic channel invasion in pT1 transitional carcinoma of bladder. Ramani, P, Birch, B R P, Harland, S J and Parkinson, M C. Histopathology. 1991; 19: 551-554.
• Sedo-analgesia with sedation reversal. Birch, B R P and Miller, R A. Journal of One-Day Surgery. 1991; 1: 5-7.
• The PorgesUrospiral: a reversible endoprostatic stent. Parker, C, Birch, B R P, Connelly, A, Briggs, T, Anson, K and Miller, R. World Journal of Urology 1991; 9: 22-25.
• Prostate. Editorial Comment. Birch, B R P. Current Opinion in Urology. 1992; 2: 113-114.
• Prostate. Editorial Comment. Birch, B R P. Current opinion in Urology. 1993; 3: 1-3.
• Anxiety in patients undergoing local anaesthetic day-case cystoscopy. Birch, B R P, Chakaraborty, R and Miller, R A.
Journal of One-Day Surgery. 1993; 3: 15-17.
• *Flexible cystoscopy in males: Is the use of topical lignocaine gel worthwhile? Birch, B R P,Ratan, P R, Morley, R, Cumming, J C, Smart, C J and Jenkins,J British Journal of Urology 1994; 73: 155-159.
• Renal arteriovenous fistula following blunt trauma. Armstrong, A L, Birch, B R P and Jenkins, J D. British Journal of Urology 1994; 73: 321-322.
Review article
• Day case surgery and urology: Present practice and future trends. Birch, B R P. British Journal of Urology. 1994; 74: 2-10.
• Low grade transitional cell carcinoma of the bladder – an unusual case of vaginal bleeding. Bass, P S, Birch, B, Smart, C S, Theaker, J M and Wells, M. Histopathology. 1994; 24: 581-583.
• Multiple epidermoid cysts of the testes – The ultrasound appearances Sanderson, A J, Birch, B R and Dewbury, K C.
Clinical Radiology. 1995; 50: 414-415.
• Prostate. Editorial Comment. Birch, B R P. Current opinion in Urology. 1994; 4: U213-U215.
• *Absorption characteristics of Lignocaine following intravesical instillation. Birch, B R P and Miller, R A. Scandinavian Journal of Urology and Nephrology. 1994; 28: 359-364.
• Walk-in, Walk-out day case genito-scrotal surgery with sedation reversal. A survey of patient attitudes and morbidity.
Birch, B R P and Miller, R A. British Journal of Urology. 1994; 74: 658-664.
• The Miller Endocut Needle: Single access direct vision core biopsy. Birch, B R P and Miller, R A. British Journal of Urology. 1995; 75: 406-409.
• *An assessment of resedation following flumazenil induced antagonism of intravenous midazolam: comparison of psychomotor and amnesic recovery with a non-sedated reference group. Birch, B R P and Miller, R A. Journal of Psychopharmacology. 1995; 9: 103-111.
• Primary Enuresis – A Urodynamic study spanning three generations. Birch, B R P Scandinavian Journal of Urology and Nephrology. 1995; 29: 285-288.
• *Adenocarcinoma of the prostate and Eaton-Lambert syndrome: A previously unreported association. Agarawal, S K, Birch, B R P and Abercrombie, G F. Scandinavian Journal of Urology and Nephrology. 1995; 29: 351-353.
• Collecting duct carcinoma: An unusual renal tumour. Armstrong, A L, Birch, B R P and Cumming J. Scandinavian Journal of Urology and Nephrology. 1996, 30: 409-410.
• Multidrug resistant (MDR) bladder cancer cells express the angiogenesis/metastasis mediator tissue factor Hayes MC, Lwaleed BA, Birch B, Cooper AJ. The Journal of Urology 1997; 157: 4.
• Water as a tumoricidal agent in bladder cancer. Solomon, L Z, Birch, B R P .and Cooper, A J. European Urology. 1998; 34: 500-504.
• *Bladder cancer recurrence by implantation of exfoliated cells: Is gamma-linoleic acid an effective tumoricidal agent?.
Solomon, L Z, Jennings, A M, Foley, S J, Birch, B R P .and Cooper, A J. British Journal of Urology. 1998; 82: 122-126.
• Is gamma-linoleic acid an effective intravesical agent for superficial bladder cancer? In vitro cytotoxicity and in vivo tolerance studies. Solomon, L Z, Jennings, A M, Hayes, M C, Bass, P S, Birch, B R P and Cooper, A J. Urological Research. 1998; 26: 11-15.
• Intravesical chemotherapy with gamma-linoleic acid becomes a realistic prospect in serum-free applications: in vitro cytotoxicity and systemic absorption studies. Solomon, L Z, Jennings, A M, Sharpe, P, Cooper, A J and Birch, B R P. Journal of Urology. 1998; 160: 2280-2283.
• A prospective trial of flexible cystodiathermy for recurrent transitional cell carcinoma of the bladder. Wedderburn, A W, Ratan, Prakash and Birch, B R P. Journal of Urology. 1999; 161: 812.-814.
• Genetic predisposition to prostate cancer. Eeles R A, ……Birch, B R P et al. Prostate cancer and prostatic diseases. 1999; 2: 9-15.
• Estramustine reversal of resistance to intravesical epirubicin chemotherapy. Jennings, A M, Solomon, L Z, Sharpe, P, Hayes, M C, Cooper, A J and Birch, B R P. European Urology. 1999; 35: 327-335.
• A model of superficial bladder cancer using fluorescent tumour cells in an organ culture system. Crook, T J, Hall, I S, Solomon, L Z, Birch, B R P .and Cooper, A J. British Journal of Urology International. 2000; 86: 886-893.
• Intravesical meglumine gamma linolenic acid. Phase I tolerability studies in patients undergoing cystectomy. Crook, T J, Hall, I S, Solomon, L Z, Bass, Paul, Cooper, A Jand Birch, B UroOncology. 2000; 1: 39-42
• Fluorescence based assay for the identification of multidrug resistance in bladder cancer. Hayes, M C, Cooper, A J, Birch, B R, Cumming, Jand Smart, C J. British Journal of Urology International. (In press)
• High risk genes predisposing to prostate cancer development – do they exist? Singh, R, Eeles RA,…..Birch, B R P,Labrie, F et al. Prostate Cancer and Prostatic diseases. 2000; 3: 241-247
• Nonhomologousbioinjectable materials in urology: ‘size matters’? Solomon, L Z, Birch B R, Cooper, A J, Davies, C L and Holmes, S A. British Journal of Urology International. 2000; 85: 641-645
• No evidence of germline PTEN mutations in familial prostate cancer. Forrest M S, Edwards S M, ………Birch, B R P et al.
J Med Genet. 2000; 37: 210-212.
• Suggestive evidence for a site specific prostate cancer gene on 1p36. Badzioch M, Eeles R A, ………Birch, B R P et al.
J Med Genet. 2000; 37: 947-948.
• The frequency of germ line mutations in the breast cancer predisposition genes BRAC1 and BRAC2 in familial prostate cancer. Gayther S A, de Foy K A F, ………Birch, B R P et al. Cancer research. 2000; 3: 4513-4518.
• Relationship between Glutathione S-TransferaseM1, P1 and T1 polymorphisms and early onset prostate cancer. Kote-Jarai z, Easton D, ………Birch, B R P et al. Pharmacogenetics. 2001; 11: 325-330.
• *Cellular resistance to Mitomycin C is associated with overexpression of MDR-1 in a urothelial cancer cell line (MGH-U1). Hayes, M C, Birch, B R, Cooper, A J and Primrose J N. British Journal of Urology International. 2001; 87: 245-250
• A case of amyloid of the urethra and review of this rare diagnosis, its natural history and management, with reference to the literature. Crook, T J, Koslowski, M, Dyer, J P, Bass, P and Birch, B R. Scandinavian Journal of Urology and Nephrology. 2002; 36: 481-486
• Progesterone: a novel adjunct to intravesical chemotherapy. Lewin, J, Cooper, A andBirch, B. British Journal of Urology International. 2002; 90: 736-741
• Intravesical meglumine gamma-linolenic acid in superficial bladder cancer: an efficacy study. Harris, N M, Crook, T J, Dyer, J P, Solomon, L Z, Bass, P, Cooper, A J and Birch, B R. European Urology. 2002; 42: 39-42
• The effects of meglumine gamma linolenic acid (MeGLA) on an organ culture model of superficial bladder cancer.
Crook T J, Dyer, J P, McCormick, R I, Birch, B R and Cooper, A J. Urological Research. 2002; 30: 59-65
• HPC2/ELAC2 polymorphisms and prostate cancer risk: analysis by age of onset of disease. Meitz J C, Edwards S M,…..Birch, B R P,Eeles RA et al. British Journal of Cancer. 2002; 87: 905-908
• Association between the GCG polymorphism of the selenium dependent GPX1 gene and the risk of young onset prostate cancer. Kote-Jarai, Z, Durocher, F,…..Birch, B R P, Eeles R A et al. Prostate Cancer and Prostatic Diseases. 2002; 5: 189-192
• Influence of cytokine gene polymorphisms on the development of prostate cancer. McCarron, S L, Edwards, S,…..Birch, B R P,Eeles, R A et al. Cancer Research. 2002; 62: 3369-3372
• An activated partial thromboplastin time (APTT) assay to detect procoagulant activity in purified seminal prostasomes
Stewart AB, Gibbs R, Lwaleed BA, Cooper AC, Birch B. European Urology 2003; 2: 92.
• Antibodies to prostasomes in prostate cancer. Stewart AB, Gibbs R, Lwaleed BA, Cooper AC, Birch B. European Urology 2003; 2: 93.
• Epirubicin and meglumine gamma-linolenic acid: a logical choice of combination therapy for patients with superficial bladder carcinoma. Harris, N M, Anderson, W R, Lwaleed, B A, Cooper, A J, Birch , B R and Solomon L Z. Cancer. 2003; 97: 71-78
• Two percent of men with early-onset prostate cancer harbor germline mutations in the BRCA2 gene. Edwards SM, Kote-Jarai Z,…..Birch, B R P,Eeles, RA et al. American Journal of Human Genetics. 2003; 72: 1-12
• Germline mutations in fumarate hydrase (FH) do not predispose to prostate cancer. Bevan, S, Edwards SM,…..Birch, B R P,Eeles, RA et al. Prostate Cancer and Prostatic diseases. 2003; 6: 12-14
• Seminal clotting and fibrinolytic balance: a possible physiological role in the male reproductive system. Lwaleed, B A, Greenfield, R S, Stewart, A, Birch, B R and Cooper, A J. Thrombosis and Haemostasis. 2004; 92: 752-766
• Prostasomes: a role in prostatic disease? Stewart, A B, Anderson, W, Delves, G, Lwaleed, B A, Birch, B and Cooper, A.
BJU International. 2004; 94: 985-9
• Current drug therapy for prostate cancer: an overview Stewart, A B, Lwaleed, B A, Douglas, D A and Birch, B R. Current Medicinal Chemistry – Anti-Cancer Agents. 2005; 5:603-612
• Does Human Semen contain a functional haemostatic system?. Lwaleed, B A, Greenfield R S, Birch, B R and Cooper A J. Thrombosis and Haemostasis. 2005; 93: 847-852
• The nuclear membrane in multidrug resistance: microinjection of epirubicin into bladder cancer cell lines. Lwaleed, B A. Greenfield, R. Royle, E. Birch, B and Cooper, A J. BJU International. 2005, 95: 1091-1098
• Seminal Factor VIII and von Willebrand Factor: a possible role of the conventional clotting system in human semen?
Featherstone, J M, Speers, A G, Hayes, M C, Cooper, A J and Birch, B R. International Journal of Andrology. 2005; 28: 31-38
• Quantitation of seminal factor IX and factor IXa in fertile, nonfertile, and vasectomy subjects: a step closer toward identifying a functional clotting system in human semen. Lwaleed, B A, Greenfield, R S, Hicks, J, Birch B R and Cooper, A J. Journal of Andrology. 2005; 26: 146-152
• Does human semen contain a functional haemostatic system? A possible role for tissue factor pathway inhibitor in fertility through semen liquefaction. Lwaleed BA, Greenfield RS, Birch BR, Cooper AJ. British Journal of Haematology 2005; 129: 12-13.
• Tissue factor synthesis and expression by human proximal tubular cells: The source of increased urinary tissue factor secretion in disease? Lwaleed BA, Vayro S, Greenfield RS, Birch BR, Cooper AJ. British Journal of Haematology 2005; 129: 19.
• Quantitation of thrombin activated fibrinolysis inhibitor (TAFI) in human semen. Lwaleed BA, Greenfield RS, Birch BR, Cooper AJ. British Journal of Haematology 2005; 129: 56.
• A possible role for tissue factor in seminal coagulum formation. Lwaleed BA, Jackson C, Greenfield RS, Steward AB, Delves G, Birch BR, Cooper A Haematologica 2005; 90: 131.
• Does human semen contain a functional haemostatic system? A possible role for tissue factor pathway inhibitor in fertility through semen liquefaction. Lwaleed BA, Greenfield RS, Birch BR, Cooper AJ. Journal of Thrombosis and Haemostasis 2005; 3: 0159.
• Quantitation of thrombin activatable fibrinolysis inhibitor (TAFI) in human semen. Lwaleed BA, Greenfield RS, Delves G, Birch BR, Cooper AJ. Journal of Thrombosis and Haemostasis 2005; 3: 0794.
• Seminal factor VIII and von Willebrand factor: A possible role of the conventional clotting system in human semen?
Lwaleed BA, Greenfield RS, Goyal A, Delves G, Royle E, Birch BR, Cooper AJ Journal of Thrombosis and Haemostasis 2005; 3: 1838.
• Tissue factor synthesis and expression by human proximal tubular cells: The source of increased urinary tissue factor secretion in disease? Lwaleed BA, Vayro S, Greenfield RS, Featherstone J, Speers A, Birch BR, Cooper AJ. Journal of Thrombosis and Haemostasis 2005; 3: 0762.
• Seminal tissue factor revisited. Lwaleed B. Jackson C. Greenfield R. Stewart A. Delves G. Birch B. Cooper A. International Journal of Andrology. 2006; 29: 360-367
• *The direct effect of nuclear pores on nuclear chemotherapeutic concentration in multidrug resistant bladder cancer: the nuclear sparing phenomenon. Lewin JM. Lwaleed BA. Cooper AJ. Birch BR. Journal of Urology. 2007; 177: 1526-1530
• The effects of dietary lycopene supplementation on human seminal plasma. Goyal A. Chopra M. Lwaleed BA. Birch B. Cooper AJ. BJU International. 2007; 99: 1456-60
• Multiple newly identified loci associated with prostate cancer susceptibility Eeles RA. Kote-Jarai Z. Al Olama AA………. Birch BR. Nature Genetics. 40(3):316-21, 2008
• Multiple loci with different cancer specificities within the 8q24 gene desert Ghoussaini M. Song H. Koessler T. Al Olama AA……….Birch BR. Journal of the National Cancer Institute. 100(13):962-6, 2008
• Antiprostasome antibodies are not an appropriate prognostic marker for prostate cancer. Stewart AB. Delves GH. Birch BR. Cooper AJ. Lwaleed BA. Scandinavian Journal of Urology & Nephrology. 43(2):104-8, 2009.
• Time-lapse live cell imaging and flow analysis of multidrug resistance reversal by verapamil in bladder cancer cell lines. Jonathan M Featherstone, Bashir A Lwaleed. Alan G Speers, Matthew C Hayes, Brian R Birch and Alan J Cooper. Urology. 2009; 74: 378-384.
• Re: Live cell imaging of multidrug resistance reversal in human primary bladder cancer explant cultures. Bashir A Lwaleed. Brian R Birch, Peter Sharpe and Alan J Cooper. Urology. 2009; 74: 1385-1386.
• A potential intravesical therapeutic. Cooper A, Lwaleed B, Birch B. Honey: Urology 2009; 74: 108.
• Multiple loci on 8q24 associated with prostate cancer susceptibility Al Olama AA. Kote-Jarai Z. Giles GG. Guy M……. Birch BR Nature Genetics. 41(10):1058-60, 2009
• Identification of seven new prostate cancer susceptibility loci through a genome-wide association study. Eeles RA. Kote-Jarai Z. Al Olama AA………. Birch BR. Nature Genetics. 41(10):1116-21, 2009.
• Identification of new genetic risk factors for prostate cancer Guy M. Kote-Jarai Z. Giles GG. Al Olama AA…….. Birch BR.
Asian Journal of Andrology. 11(1):49-55, 2009
• Association of folate-pathway gene polymorphisms with the risk of prostate cancer: a population-based nested case-control study, systematic review, and meta-analysis Collin SM. Metcalfe C. Zuccolo L. Lewis SJ. Chen L…… Birch BR. Cancer Epidemiology, Biomarkers & Prevention. 18(9):2528-39, 2009
• The effect of honey on mast-cell degranulation: a possible role in painful bladder syndrome/interstitial cystitis (PBS/IC). Birch B, Murray T, Cooper A, Lwaleed B. The Journal of Urology 2011; 185: e381-e382
• Hypercoagulable states post-pregnancy: tissue factor and tissue factor pathway inhibitor imbalance in women with a history of preeclampsia. Lwaleed BA, Breish MO, Birch BR, ChowdharyAzeem, Kazmi RS, Dusse LM, Cooper AJ. British Journal of Haematology 2013: 161: 32.
• The effect of androgen deprivation therapy in prostatic adenocarcinoma on the coagulation pathway and its implication for cardiovascular risk. Perigo O, Birch BR, Breish MO, Kazmi RS, Cooper AJ, Lwaleed BA. British Journal of Haematology 2013: 161: 35.
• *Male sex hormones and systemic inflammation in Alzheimers disease. Butchart J, Birch B et al.,
Alzheimers disease & Associated Disorders 27(2):153-6, 2013
• Fourier-Transform Infrared absorbance imaging of live adherent cells under non-aqueous media.
Soh JY, Chueng A, Birch BR, Cooper AJ, Lwaleed BA. Journal of Clinical Pathology 66(4):312-8, 2013.
• *Depression and anxiety in prostate cancer: a systematic review and meta-analysis of prevalence rates. Watts S. Leydon G. Birch B. Prescott P. Lai L. Eardley S. Lewith G. BMJ Open. 4(3):e003901, 2014.
• Plasma tissue factor and cytokine levels during long-term catheterisations Lwaleed, B. A.; Cooper, A. J.; Fader, M.; Birch, B. R. et al. British Journal of Haematology 165: Special Issue: SI Supplement: 1 Pages: 37-37 May 2014
• *Inhibition of mast cell degranulation by honey in-vitro: potential as a treatment option in inflammatory conditions
Lwaleed, B. A.; Kambara, T.; Birch, B. R.; et al. British Journal of Haematology 165: Special Issue: SI Supplement: 1 Pages: 25 May 2014
• *The evolution of the Southampton Enhanced Recovery Program for radical cystectomy and the aggregation of marginal gains Julian Smith, Zhao Wu Meng, Richard Lockyer, Tim Dudderidge, John McGrath, Matthew Hayes and Brian Birch
BJU International. 114(3):375-83, 2014
• Tissue factor and tissue factor pathway inhibitor in women with a past history of preeclampsia: implication for a hypercoagulable state postpregnancy. Lwaleed BA; Breish MO; Birch BR; Chowdhary AP; Saad RA; Perigo O; Kazmi RS; Dusse LM; Cooper AJ. Blood Coagulation & Fibrinolysis. 25(7):671-4, 2014 Oct.
• Plasma Tissue factor and cytokine levels during long-term catheterisations. Lwaleed BA, Cooper AJ, Fader M, Birch BR.
British Journal of Haematology 2014; 165: 37.
• *Opioid analgesic drugs: Do they influence bladder cancer cell growth? Giatsidou L, Cooper AJ, Lwaleed BA, Birch BR.
Urology 2014; 84: 191.
• *The role of bladder stretching in maintaining bladder health: plasma cytokine levels in catheterised patients using valves or continuous drainage. Lwaleed BA, Fader M, Birch BR, Cooper AJ. BJU International 2015; 115: 42.
• Health related quality of life (HRQoL) after cystectomy: comparison between orthotopicneobladder and ileal conduit diversion. [Review] Ali AS; Hayes MC; Birch B; Dudderidge T; Somani BK. European Journal of Surgical Oncology. 41(3):295-9, 2015 Mar.
• *A quantitative analysis of the prevalence of clinical depression and anxiety in patients with prostate cancer undergoing active surveillance. Watts S; Leydon G; Eyles C; Moore CM; Richardson A; Birch B; Prescott P; Powell C; Lewith G.
BMJ Open. 5(5):e006674, 2015.
• A trial of devices for urinary incontinence after treatment for prostate cancer. Macaulay M; Broadbridge J; Gage H; Williams P; Birch B; Moore KN; Cottenden A; Fader MJ. BJU International. 116(3):432-42, 2015 Sep.
• PROACTIVE: PROSTATE Cancer Support Intervention for Active Surveillance: protocol for a multi-centre feasibility trial
Lewith, George; Watts, Sam; Richardson, Alison;….Birch, Brian et al. Psycho-oncology Volume: 25 Special Issue: SI Supplement: 1 Pages: 16-16 March 2016
• Tissue factor and inflammatory cytokines in urine and plasma of catheterised patients managed using valves or free drainage Lwaleed, B. A.; Tan, X.; Talukdar, T.; Birch B. R. et al. British Journal of Haematology Volume: 173 Special Issue: SI Supplement: 1 Pages: 170-170 April 2016
• *The role of bladder filling and voiding in maintaining bladder health: urinary and plasma cytokines in catheterised patients using valves or on free drainage Lwaleed, B.; Tan, X.; Tudball, T.; Birch, Bet al. Neurology and UrodynamicsVolume: 35 Supplement: 4 Pages: S448-S449 August 2016
• Artemisinins as potential anticancer agents: uptake detection in erythrocytes using Fourier transform infrared spectroscopy and cytotoxicity against bladder cancer cells Humphreys, Charlotte; Cooper, Alan J.; Barbu, Eugen; Birch, Brian R et al. Journal of Clinical Pathology Volume: 69 Issue: 11 Pages: 962-967 November 2016
• Bladder cancer in younger adults: Clinicopathological features and therapeutic outcomes. Albayati MA, Pandian SS, Lwaleed BA and Birch BR Journal of Urology Renal Diseases 2016: J110.
• The role of bladder stretching in maintaining bladder health: urine and plasma inflammatory levels in catheterised patients using valves or on free drainage. Lwaleed BA, Tan X, Fader M, Talukdar T, Tudball T, Cooper AJ and Birch BR. Journal of Clinical Urology 2016; 9: 75.
• Artemisinin derivatives inhibit proliferation in bladder cancer cells and pseudo-tubule formation by HUVEC cells. Humphreys C, Cooper AJ, Birch BR, Lwaleed BA. Journal of Clinical Urology 2016; 9: 80.
• *The Distribution of Mast Cells in Interstitial Cystitis. Malik ST, Crome G, Birch BR, Voegeli D, Cooper AJ, Lwaleed BA.
Journal of Clinical Urology 2016; 9: 82-83.
• Tissue Factor and Inflammatory Cytokines Levels in Urine and Plasma of Catheterised Patients Using Valves or on Free Drainage. Lwaleed BA, Tan X, Talukdar T, Tudball T, Cooper AJ, Birch BR, Fader M. British Journal of Haematology 2016; 173: 170.
• Haemostatic and Inflammatory Changes Following Pre-eclampsia: Potential Link with Development of Subsequent Cardiovascular Events? Abad, Tan X, van Rijn BB, Birch BR, Cooper AJ, Lwaleed BA. British Journal of Haematology 2016; 173: 62-63.
• The role of testosterone in prostate cancer growth: Is the growth response of LNCaP and PC3 cells to exogenously applied testosterone in vitro saturation dependent? Hald O, Lwaleed B and Birch B. The fifth Global Congress on Prostate Cancer. Convento Do Beato, Lisbon, Portugal, 28th – 30th June, 2017 (Abstract number 29, abstract book: ISBN 789462210141).
• Do patients with a history of pre-eclampsia have elevated levels of coagulation and angiogenic markers postpartum?
Abad F, Rathod S, van Rijn BB, Lwaleed BA. British Journal of Haematology 2017; 176: 118.
• *Diluted honey inhibits biofilm formation: potential application in urinary catheter management? Emineke, Somadina; Cooper, Alan J.; Fouch, Sarah; Birch, Brian Ret al. Journal of Clinical Pathology Volume: 70 Issue: 2 Pages: 140-144 February 2017
• Mast cell subtypes: implications for the pathogenesis of interstitial cystitis Birch, Brian; Malik, Shabana; Lwaleed, Bashir Journal of Urology Volume: 197 Issue: 4 Supplement: S Pages: E387-E387 April 2017
• The effect of morphine and its inhibitors on RT112 bladder cancer cell growth Birch, Brian; Lwaleed, Bashir; Cooper, Alan; et al. Journal Of Urology Volume: 197 Issue: 4 Supplement: S Pages: E640-E641April 2017
• Surgical management of the neurogenic bladder after spinal cord injury Jean-Jacques Wyndaele,Brian Birch, Albert Borau et al. World J Urology (in submission)
• The Distribution of Mast Cell Subtypes in Interstitial Cystitis: Implications for novel diagnostic and therapeutic strategies? Malik, Shabana; Birch, Brian et al Journal of Clinical Pathology (in review)
• Honey inhibits mast cell degranulation in in vitro models: implications for management of interstitial cystitis, including comparisons with conventional agents. Lwaleed BA, Kambara T, Lau LC, Voegeli D, Fader M, Cooper A, Birch B. BJU International (In submission). 
Review Articles in Academic Publications
Review article
• *The pT1 G3 Bladder Tumour. Birch, B R P and Harland S J. British Journal of Urology 1989; 64: 109-116.
Review Article
• Percutaneous Nephrolithotomy. Birch, B R P and Miller, R A. Surgery 1989; 70: 1680-1683.
Review article
• Day case surgery and urology: Present practice and future trends. Birch, B R P. British Journal of Urology. 1994; 74: 2-10.
Review article
• Current drug therapy for prostate cancer: an overview Stewart, A B, Lwaleed, B A, Douglas, D A and Birch, B R.
Current Medicinal Chemistry – Anti-Cancer Agents. 2005; 5:603-612

Reviews of Single Academic Books
• B R P Birch. Prostate cancer and bone metastases. Eds. Karr J P and Yamanaka H. In Hematology Reviews 1994; 8: 239-240.
• B R P Birch. Superficial bladder cancer. Eds. Pagano F and Fair W R. In Hematology Reviews 1994; 8: 239-240
• B R P Birch. Controversies in the treatment of prostate cancer. Eds. Moser, L; Miller, K and Hinkelbein, W. In Oncology News 2008; 3: 11.
• B R P Birch. The Oxford Handbook of Urology 4th edition April 2017.