Alexandros Charalabopoulos, MD, PhD, FRCS

Consultant Upper GI & General Surgeon
Mid Essex Hospital Services NHS Trust
Broomfield Hospital
Broomfield, Chelmsford
Essex CM1 7ET, UK

Biography

Consultant Upper GI & General Surgeon with an interest in Minimally Invasive Oesophagogastric Cancer Surgery.

Broomfield Hospital, Mid Essex Hospital Services NHS Trust

Permanent full time post from December 2013

As an Upper GI & General Surgery Consultant with a major interest in oesophagogastric cancer resection surgery, I perform all the operations in the spectrum of upper gastrointestinal surgery and mainly in the field of upper GI cancer surgery and its minimally invasive treatment. Broomfield Hospital is a high volume and the regional oesophagogastric cancer center in which more than 100 oesophagogastric resections per year are performed. I perform all types of oesophagectomies with the majority being laparoscopic assisted Ivor-Lewis oesophagogastrectomies and all the types of gastrectomies. Most of the elective operations I perform are laparoscopic. I perform upper GI and general surgical operations like laparoscopic incisional and inguinal (TEP and TAPP) hernia repair, laparoscopic cholecystectomy and CBD exploration, laparoscopic fundoplication, and laparoscopic Heller’s myotomy. I perform robotic upper GI surgery and especially robotic assisted Heller’s myotomy, robotic gastric resections and robotic gastric pacing. I also have a special interest in the treatment of gastroparesis and I am one of the two surgeons in the region who specializes in gastric pacing. I do general surgical on calls in a 1 in 8 rota. I perform upper GI diagnostic and therapeutic endoscopy and do upper GI and general surgical clinics. I am also a key member of the upper GI cancer MDT meetings.
As an Upper GI Surgeon I have been extensively trained in all types of oesophagectomies (Ivor-Lewis, McKeown, transhiatal, thoracoabdominal, minimal invasive), gastrectomies with extensive lymph node dissections (D1, D2 and even D3), bariatric surgery (gastric bypass, sleeve gastrectomy, gastric band, intragastric balloon) and laparoscopic benign upper GI disease. I have received expert training in Upper GI surgery from internationally renowned units. Specifically, cancer resections through fellowships from Broomfield Hospital in Chelmsford, National Cancer Centre Hospital in Tokyo, St Thomas’ Hospital in London and upper GI advanced laparoscopic procedures including bariatric surgery from St Thomas’ and St George’s Hospitals in London. I have also had advanced training in general surgery (mainly HPB, colorectal, endocrine, vascular) and was awarded an MSc and a PhD for my research in experimental acute pancreatitis and gastrointestinal carcinogenesis respectively. So far I have participated in about 3000 operations, the great majority of which is in the field of Upper GI surgery, having performed more than 1800 of those.

Research Interest

His research interests include: oesophagogastric cancer resection surgery, treatment of gastroparesis

Scientific Activities

INVITED SPEAKER

1. Bariatric surgery. Operations and pitfalls. Chairman: Mr A Botha. FY2/CT/SHO Surgical Education Day. Guy?s and St Thomas? Education Centre, London, UK. 07 Feb 2013
2. Complications of bariatric surgery. Round table. Chairman: Dr S Chong. South Thames Gut Club Meeting. Post Grad Lecture Theatre, St Helier Hospital. London, UK. 24 Nov 2011.
3. Round Table: The role of adhesion molecules in cancer. New useful tools. Topic: Cadherins. 15th Scientific Congress of Greek Medical School Students & 3rd International Forum of Medical Students and Young Doctors of Greece. Thessaloniki, Greece, 8-10 May 2009.
4. Surgical anatomy of the liver and types of hepatectomies. Higher Surgical Training Meeting of University of Athens. Attikon University Hospital, Athens, Greece. June 2009.
5. Respiratory failure and its prevention in the surgical patient. Higher Surgical Training Meeting of University of Athens. Attikon University Hospital, Athens, Greece. Feb 2008.
6. Oesophageal resection with colonic interposition. Round table. Chairman: Prof Liakakos. 1st Joined Meeting of the Travelling Surgical Society of Great Britain and Northern Ireland and the Third Academic Department of Surgery of the University of Athens. Attikon University Hospital, Athens, Greece. Sept 2008.
7. Spontaneous kidney rupture. A&E East Anglia Meeting. Peterborough Hospital, Peterborough, UK. April 2006.
8. Surgical pathology of liver and spleen. Basic Surgical Training Meeting. Post graduate center, Peterborough Hospital, Peterborough, UK. July 2005.
8. Surgical pathology of liver and spleen. Basic Surgical Training Meeting. Post graduate center, Peterborough Hospital, Peterborough, UK. July 2005.
9. Sore throat. ENT East Anglia Meeting. Peterborough Hospital, Peterborough, UK. Oct 2005.
10. Sensorineural hearing loss. ENT East Anglia Meeting. Peterborough Hospital, Peterborough, UK. Jan 2006.
11. Management of surgical infection. Basic Surgical Training Meeting. Post graduate center, Peterborough Hospital, Peterborough, UK. July 2005.

MEMBER OF COMMITTEES/SOCIETIES

• Member of AUGIS – Association of Upper Gastrointestinal Surgeons of Great Britain & Ireland
• Member of BOMMS- British Obesity & Metabolic Surgery Society
• Member and Fellow of RCSEng – The Royal College of Surgeons of England
• Member of EA-HPB-A – European-African Hepato-Pancreato-Biliary Association
• Member of HPB-HS – The Hepato-Pancreato-Biliary Hellenic Society

Publications

PUBLICATIONS IN PEER REVIEWED INTERNATIONAL JOURNALS IN THE LAST 5 YEARS INCLUDE:

1. Charalabopoulos A, Golias C. E-cadherin expression in Barretts esophagus and esophageal carcinoma. Esophagus. 2014.
2. Charalabopoulos A, Lambropoulou M, Papalois A, Papachristou F, Simopoulos C, Tsaroucha A. Does apigenin exert a prophylactic effect in acute pancreatitis An experimental study evaluating pancreatic TNF- expression. J Surg Res. 2013.
3. Charalabopoulos A, Botha AJ. Laparoscopic cholecystectomy in the presence of lumboperitoneal shunt. Case Rep Surg. 2013; doi: 10.1155/2013/929082.
4. Machairas A, Tsapralis D, Samaras VD, et al. Basaloid squamous cell carcinoma of the rectum. A rare entity. J Med Cases. 2013; 4(8): 535-539.
5. Machairas A, Petropoulos K, Machairas N, Charalabopoulos A, Misiakos EP. Image of the month. Choledochocele. Arch Surg. 2011; 146(10): 1213-1214. doi: 10.1001/archsurg.2011.263-a.
6. Golias C, Batistatou A, Bablekos G, et al. Physiology and pathophysiology of selectins, integrins, and IgSF cell adhesion molecules focusing on inflammation. A paradigm model on infectious endocarditis. Cell Commun Adhes. 2011; 18(3): 19-32. doi: 10.3109/15419061.2011.606381.
7. Misiakos EP, Siama E, Schizas D, et al. Massive Uterine Leiomyoma in a Patient with Friedreichs Ataxia: Is There a Possible Association. Case Report Med. 2011; 2011:648217. doi: 10.1155/2011/648217.
8. Charalabopoulos K, Makris G, Charalabopoulos A, Golias C, Athanasiou K. Public knowledge, beliefs and practices in Greece about cancer etiology and prevention. East Mediterr Health J. 2011; 17(5): 392-397.
9. Charalabopoulos K, Krivan S, Machairas N, Misiakos , Machairas. Endopancreatic bile duct cholangiocarcinoma in a patient with Peutz-Jeghers syndrome. HPB Surgery. 2011; 2011: 364570. doi: 10.1155/2011/364570.
10. Charalabopoulos , Macheras , Krivan S, Petropoulos K, Misiakos , Macheras A. Arteriovenous malformation of the pancreas. Case Reports Med. 2011; 2011: 612657.
11. Charalabopoulos A, Misiakos E, Macheras A. Colocutaneous fistula complicating sigmoid diverticulitis. Int J Surg Case Rep. 2011; 2: 68-70.
12. Batistatou A, Charalabopoulos A, Charalabopoulos K. Molecular basis of colorectal cancer. N Engl J Med. 2010; 362(13): 1246.
13. Tsapralis D, Charalabopoulos A, Karamitopoulou E, et al. Pancreatic intraductal papillary mucinous neoplasm with concomitant heterotopic pancreatic cystic neoplasia of the stomach: a case report and review of the literature. Diagn Pathol. 010; 5: 4. doi: 10.1186/1746-1596-5-4.
14. Charalampopoulos A, Charalabopoulos A, Batistatou A, et al. Parathormone and 1,25(OH)2D3 but not 25(OH)D3 serum levels, in an inverse correlation, reveal an association with advanced stages of colorectal cancer. Clin Exp Med. 2010; 10(1): 69-72. doi: 10.1007/s10238-009-0069-6.
15. Charalabopoulos A, Misiakos EP, Foukas P, et al. Localized peripancreatic plasma cell Castleman disease. Am J Surg. 2010; 199(5): 51-3. doi: 10.1016/j.amjsurg.2009.05.020.
16. Yiotakis I, Georgolios A, Charalabopoulos A, et al. Primary localized laryngeal amyloidosis presenting with hoarseness and dysphagia: a case report. J Med Case Reports. 2009; 3: 9049. doi: 10.4076/1752-1947-3-9049.
17. Charalabopoulos K, Kotsalos A, Batistatou A, et al. Serum and tissue selenium levels in gastric cancer patients and correlation with CEA. Anticancer Res. 2009; 29(8):3465-7.
18. Batistatou A, Charalabopoulos A, Charalabopoulos K. Molecular basis of metastasis. N Engl J Med. 2009; 360(16): 1679. doi: 10.1056/NEJMra0805239.
19. Charalampopoulos A, Macheras A, Charalabopoulos A, Fotiadis C, Charalabopoulos K. Iliopsoas bscesses: diagnostic, aetiologic and therapeutic approach in five patients with a literature review. Scand J Gastroenterol. 2009; 44(5): 594-599. doi: 10.1080/00365520902745054.
20. Fareed KR, Charalabopoulos A.Minimally invasive oesophagectomy. Surg Res Open J. 2015; 2(1): e1-e2. doi: 10.17140/SROJ-2-e001
21. Rashid F, Charalabopoulos A. Laparoscopic gastrectomy for gastric cancer. Surg Res Open J. 2016; 3(1): e3-e5. doi: 10.17140/SROJ-3-e002