Associate Editor


Zeev Blumenfeld, MD

Associate Professor
Reproductive Endocrinology
Department of Obstetrics and Gynaecology
Rambam Health Care Campus
Rappaport School of Medicine
Technion-Faculty of Medicine
Haifa, 31096, Israel

Biography

ACADEMIC DEGREE


• (1976) MD - Hebrew University and Hadassah Medical School, Jerusalem


ACADEMIC APPOINTMENTS


• (1994) Associate Professor of Obstetrics & Gynecology, Faculty of Medicine, Technion
• (1990-1994) Senior Lecturer, Technion
• (1969-1973) Research and teaching assistant at the Department of Anatomy and Embryology; Hebrew University and Hadassah Medical School (Teaching anatomy, embryology, and neuroanatomy)
• (1973-1974) Associate teaching fellow in the Department of Anatomy and Morphologic Sciences, Technion

Research Interest

His research interests include: Prevention of Premature Ovarian Failure (POF) in young women receiving gonadotoxic chemotherapy, Reproductive Endocrinology, Inhibin & Activin in Human Reproduction, Hypophysiotropic and Neuregulatory Modulation of Fetal Human Pituitary, Infertility and Assisted Reproduction (ART) and Immunologic Problems in Infertility.

Scientific Activities

MEMBERSHIP IN PROFESSIONAL SOCIETIES


INTERNATIONAL


• Society for Gynecologic Investigation (Membership # 462-114) (1987-Present)
• The Endocrine Society, (Membership # 138759) Membership (1987-Present)
• Israel National Representative to ESHRE [European Society of Human Reproduction & Embryology] (2012-Present)
• New York Academy of Sciences (Membership # 336939) (1990-2013)
• American Society for Reproductive Medicine (former- American Fertility Society) (1983-Present)
• European Society of Human Reproduction and Embryology (2010-Present)
• Member of the executive committee of ESHRE [European Society of Human Reproduction & Embryology] task force of Fertility Preservation in Severe Diseases (2007-2011)
• Reproductive Biology Professional Group International Society of Gynecological Endocrinology (1989-Present)
• Member of Research Board of Advisors (ABI) (2000-Present)
• Member of Board of Advisors (Fertile Hope) (2000-Present)
• Member of International Society of Fertility Preservation (2008-Present)
• Member of COPE-Committee on Publication Ethics (2012-Present)


NATIONAL


• Israeli Endocrine Society. Member of the executive council (2008-2012)
• Israeli Society for Fertility Research [AYALA-[אילה - member of directory council (1991-1995)


HONORS


• (1970-1973) Maurberger prize [for four years]-excellence in medical studies, Hebrew University, Jerusalem
• (1988) Received the Polishuk award for the research: Luteal Dysfunction in Ovulation Induction - The Role of Repetitive Human Chorionic Gonadotropin Supplementation during the Luteal Phase - The annual meeting of the Israeli Society for Reproduction Research
• (1991) The Zondek Prize for the best abstract 1990-91, the annual meeting of the Israeli Endocrine Society (IES)
• (1991) Growth hormone-binding protein (GH-BP) correlation with estrogen, progesterone, and gonadotropins in human: The effect of ovulation induction with growth hormone, hMG, and gestation
• (1991) Elected as member of the Society for Gynecologic Investigation
• (1992) Prize of the Israel Fertility Society for the research Growth Hormone - Binding Protein regulation in preovulatory follicles: Correlation with serum GH-BP levels
• (1992) Member-Board Examinations, Obstetrics & Gynecology, Israeli Scientific Council
• (1999-2000) Member of European Community Jury-grants evaluation, Brussels, Belgium
• (2007-2010) Member of the ESHRE task force Fertility Preservation in Severe Disease
• (2007) Nomination as Outstanding reviewer of Fertility and Sterility
• (2008) Editor in Chief- Clinical Medicine Insight: Reproductive Health
• (2013) Editor in Chief- Journal of Reproductive Biology and Health
• (2010) The best clinical poster Prize, the 39th annual meeting of the Israeli Endocrine Society (IES):The protective effect of GnRH-a against chemotherapy associated gonadal failure in stem cell transplantation
• (2011) Prize poster, the annual meeting of the Society for Gynecologic investigation (SGI), Miami beach, Florida, US: The protective effect of GnRH-a against chemotherapy associated gonadal failure in stem cell transplantation
• (2011-Present) National representative in ESHRE

Publications

REFEREED PAPERS IN PROFESSIONAL JOURNALS


BASIC


1. Makler A, Blumenfeld Z, Brandes JM, Paldi E. Factors affecting sperm motility. Human sperm velocity and percentage of motility as influenced by semen dilution. Fertil Steril. 1979; 32: 442.
2. Makler A, Blumenfeld Z. Optimum measurements time for human sperm velocity determination. Arch Androl. 1980; 5: 89-194. doi: 10.3109/01485018008986314)
3. Makler A, Blumenfeld Z, David R, Better OS. Factors affecting sperm motility: VII - sperm motility as affected by change of pH and osmolarity of semen and urine specimens. Fertil Steril. 1981; 36: 507.
4. Blumenfeld Z, Kerner H, Thaler I, Deutsch M, Beck D. Increased alpha fetoprotein levels in mixed mesodermal tumors of ovary. Gynecol and Obstet Invest. 1984; 17: 169-173.
5. Blumenfeld Z, Makler A, Gershon H, Brandes JM. An improved sperm immobilization test based on multiple exposure photography technique. Am J Reprod Immunol and Microbiol. 1985; 7: 27-31.
6. Blumenfeld Z, Kuhn RW, Jaffe RB. Corticotropin-releasing factor can stimulate gonadotropin secretion by human fetal pituitaries in superfusion. Am J Obstet Gynecol. 1986; 154: 606-612.
7. Blumenfeld Z, Jaffe RB. Hypophysiotropic and neuroregulatory modulation of ACTH secretion by human fetal pituitary. J Clin Investig. 1986; 78: 288-294.
8. Monroe SE, Blumenfeld Z, Andreyko JL, Schriock E, Henzl MR, Jaffe RB. Dose-Dependent Inhibition of Pituitary-Ovarian Function during Administration of a GnRH Agonistic Analog (Nafarelin). J Clin Endocrinol Metabolism. 1986; 63: 1334-1341. doi: http://dx.doi.org/10.1210/jcem-63-6-1334
9. Blumenfeld Z, Gershon H, Makler A, Stoler J, Brandes JM. Detection of antisperm antibodies: A cytotoxicity immobilization test. Int J Fertil. 1986; 31: 207-212.
10. Mulchahey J, DiBlasio AM, Martin CM, Blumenfeld Z, Jaffe RB. Hormone production and peptide regulation of the human fetal pituitary gland. Endocrine Reviews. 1987; 8: 406-422. doi: http://dx.doi.org/10.1210/edrv-8-4-406
11. Jaffe RB, Mulchahey JJ, DiBlasio AM, Martin C, Blumenfeld Z, Dumesic DA. Peptide regulation of pituitary and target tissue function and growth in the primate fetus. Proceedings of the Laurenthian Hormone Conference. Recent Progress in Hormone Research. 1988; 44: 431-459.
12. Jaffe RB, DiBlasio AM, Blumenfeld Z, Martin MC, Seron-Ferre M. Neuroendocrine regulation of hormonal function and growth in the primate fetal hypothalamic-pituitary-adrenal system. Perinatal Press. 1989.
13. Nahhas F, Blumenfeld Z. The zona-free hamster egg penetration assay: Prognostic indicator in IVF program. Archives of Andrology. 1989; 23: 33-37.
14. Blumenfeld Z, Tapanainen P, Kaplan S, Grumbach M, Jaffe RB. Partial loss of responsiveness of human fetal pituitary cells to hGHRH after chronic exposure. Acta Endocrinologica. 1989; 121: 721-726. doi: 10.1530/acta.0.1210721
15. Blumenfeld Z, Weiner Z, Lorber M, Sujov P, Thaler I. Anticardiolipin antibodies in patients with recurrent pregnancy wastage: Treatment and uterine blood flow. Obstet Gynecol. 1991;78: 584-589.
16. Blumenfeld Z, Amit T, Barkey RJ, Lunenfeld B, Brandes JM. The synergistic effect of growth hormone and gonadotropins in achievement of conceptions in clonidine negative patients with unexplained infertility. New York Academy of Sciences. 1991; 626: 250-266. doi: 10.1111/j.1749-6632.1991.tb37920.x
17. Makler A, Makler-Shiran E, Stoler J, Lissak A, Abramovici H, Blumenfeld Z. Use of a sealed mini-chamber to investigate human sperm motility under aerobic and unaerobic conditions. Archives of Andrology. 1992; 29: 255-261.
18. Blumenfeld Z, Barkey RJ, Youdim MBH, Brandes JM, Amit T. Growth hormone - binding protein regulation by estrogen, progesterone, and gonadotropins in human: The effect of ovulation induction with menopausal gonadotropins, GH and gestation. J Clin Endocrinol Metabol. 1992; 75: 1242-1249.
19. Makler A, Reiss J, Stoler J, Blumenfeld Z, Brandes JM. Use of a sealed mini-chamber for direct observation and evaluation of the in-vitro effect of cigarette smoke on sperm motility. Fertil Steril. 1993; 59: 645-651.
20. Blumenfeld Z, Halachmi S, Pertz B, et al. Premature ovarian failure - The prognostic application of autoimmunity on conception after ovulation induction. Fertility and Sterility. 1993; 59: 750-755.
21. Amit T, Dirnfeld M, Barkey RJ, et al. Growth hormone - binding protein (GH-BP) levels in follicular fluid from human preovulatory follicles: Correlation with serum GH-BP levels. J Clin Endocrinol Metabol. 1993; 77: 33-39. doi: http://dx.doi.org/10.1210/jcem.77.1.8325956
22. Blumenfeld Z, Amit T. The role of GH in ovulation induction. Annals of Medicine. 1994; 9: 209-213.
23. Blumenfeld Z, Dirnfeld M, Gonen Y, Abramovici H, Brandes JM. Growth hormone cotreatment for ovulation induction may enhance conception in the cotreatment and in the succeeding cycles, in clonidine negative but not in clonidine positive patients. Human Reproduction. 1994; 94: 209-213.
24. Makler A, Yoffe N, Reichler A, Stoler J, Blumenfeld Z. Inability of human sperm to change their orientation in response to external chemical stimuli. Fertil Steril. 1995; 63: 1077-1082.
25. Shiran E, Stoller J, Blumenfeld Z, Feigin FD, Makler A. Evaluation of the accuracy of different counting chambers using strict counts of photographed beads. J Assist. Reprod and Genetics. 1995; 12: 434-442.
26. Blumenfeld Z, Amit T. The role of growth hormone (GH), GH-receptor and GH-binding protein in reproduction and ovulation induction. Journal of Pediat Endocrinol Metabol. 1996; 9: 145-162.
27. Avivi I, Polak S, Gideoni O, Linn S, Blumenfeld Z. Overdiagnosis of 21-hydroxylase late onset congenital adrenal hyperplasia: Correlation of corticotropin test and human leukocyte antigen typing. Fertil Steril. 1996; 66: 557-563.
28. Blumenfeld Z, Avivi I, Linn S, Epelbaum R, Ben-Shahar M, Haim N. Prevention of irreversible chemotherapy-induced ovarian damange in young women with lymphoma by a gonadotropin-releasing hormone agonist in parallel to chemotherapy. Human Reproduction. 1996; 11: 1620-1626.
29. Brenner B, Mandel H, Lanir N, et al. Activated protein C resistance can be associated with recurrent fetal loss. Br J Haematology. 1997; 97: 551-554.
30. Brenner B, Blumenfeld Z. Thrombophilia and fetal loss. Blood reviews. 1997; 1: 72-79.
31. Blumenfeld Z, Haim N. Prevention of gonadal damage during cytotoxic therapy. Annals of Medicine. 1997; 29: 199-206.
32. Jabareen A. Blumenfeld Z. Younis J, Lanir N, Brenner B. Prevention of recurrent fetal loss and gestational thromboembolism by enoxaparine. Thromb. Haemostasis. 1997; 783.
33. Ornoy A, Yacobi S, Avraham S, Blumenfeld Z. The effect of sera from women with systemic lupus erythematosus and/or antiphospholipid syndrome on rat embryos in culture. Reproductive Toxicology. 1998; 12: 185-191. doi: 10.1016/S0890-6238(97)00149-4
34. Blumenfeld Z, Ritter M, Shen-Or Z, Shariki K, Ben-Shahar M, Haim N. Inhibin-A concentrations in the sera of young women during and after chemotherapy for lymphoma: Correlation with ovarian toxicity. Am J Reprod Immunol. 1998; 39: 33-40.
35. Krause I, Blumenfeld Z, Malchinsky M, et al. Anti-endothelial cell antibodies in the sera of hyperprolactinemic women. Lupus. 1998; 7: 377-382.
36. Brenner B, Sarig G. Weiner Z, Younis J, Blumenfeld Z, Lanir N. Thrombophilic polymorphisms are common in women with fetal loss without apparent cause. Throm Haemost. 1999; 82: 6-9.
37. Sun QY, Blumenfeld Z, Rubinstein S, Goldman S, Gonen Y, Breitbart H. Mitogen-activated protein kinase in human eggs. Zygote, 1999; 7: 181-185.
38. Blumenfeld Z, Avivi I, Ritter M, Rowe JM. Preservation of fertility and ovarian function and minimizing chemotherapy-induced gonadotoxicity in young women. J Soc Gynecol Invest. 1999; 6: 229-239.
39. Blumenfeld Z, Brenner B. Thrombophilia associated pregnancy wastage. Fertil Steril. 1999; 72: 765-774. doi: http://dx.doi.org/10.1016/S0015-0282(99)00360-X
40. Brenner B, Hoffman R, Blumenfeld Z, Weiner Z, Younis J. Enoxaparin improves gestational outcome in thrombophilic women with recurrent pregnancy loss. Throm Haemost. 2000; 83: 693-697.
41. Yacobi S, Ornoy A, Blumenfeld Z. Miller RK. The effect of sera from women with systemic lupus erythematosus (SLE) and recurrent abortions on the proliferation and death of human trophoblastic cells in culture. Placenta. 2000; 21: A37.
42. Blumenfeld Z. Ovarian rescue/protection from chemotherapeutic agents. J Soc.Gynecol Invest. 2001; 8: S60-S64.
43. Blumenfeld Z, Ritter M. Inhibin, Activin, and Follistatin in Human Fetal Pituitary and Gonadal Physiology. Ann NY Acad Sci. 2001; 943: 34-48. doi: 10.1111/j.1749-6632.2001.tb03788.x
44. Blumenfeld Z. Response of human fetal pituitary cells to activin, inhibin, hypophysiotropic and neuroregulatory factors in vitro. Early Pregnancy. 2001; 5: 41-42.
45. Sarig G, Younis J, Hoffman R, Lanir N, Blumenfeld Z, Brenner B. Thrombophilia is common in women with pregnancy loss and is associated with late pregnancy wastage. Fertil Steril. 2002; 77: 342-347. doi: http://dx.doi.org/10.1016/S0015-0282(01)02971-5
46. Blumenfeld Z. Preservation of fertility and ovarian function and minimalization of chemotherapy associated gonadotoxicity and premature ovarian failure: the role of inhibin –A and –B as markers. Molecular Cellular Endocrinology. 2002; 187: 93-105. doi: 10.1016/S0303-7207(01)00712-2
47. Blumenfeld Z, Dann E, Avivi I, Epelbaum R, Rowe JM. Fertility after treatment for Hodgkins disease. Annals of Oncology. 2002; 13(Suppl 1): 138-147. doi: 10.1093/annonc/13.S1.138
48. Yacobi S, Ornoy A, Blumenfeld Z, Miller RK. The effect of sera from women with Systemic Lupus Erythematosus or Antiphospholipid Syndrome and recurrent abortions on human placental explants in culture. Teratology. 2002; 66: 300-308. doi: 10.1002/tera.10107
49. Blumenfeld Z. Review-Fertility after chemotherapy. Hungarian J of Gynecologic Oncology. 2002; 7: 27-40. doi: 10.1177/107815529600200201
50. Matalon ST, Shoenfeld Y, Blank M, Yacobi S, Blumenfeld Z, Ornoy A. The effects of IgG purified from women with SLE and associated pregnancy loss on rat embryos in culture. Am J Reprod Immunol. 2002; 48: 296-304. doi: 10.1034/j.1600-0897.2002.01084.x
51. Ornoy A, Yacobi S, Matalon ST, et al. The effects of antiphospholipid antibodies obtained from women with SLE/APS and associated pregnancy loss on rat embryos and placental explants in culture. Lupus. 2003; 12: 573-578.
52. Blumenfeld Z. Hormonal suppressive therapy for endometriosis may not improve patient health. Fertility and Sterility. 2004; 81: 487-492. doi: http://dx.doi.org/10.1016/j.fertnstert.2003.07.038
53. Boulman N, Levy Y, et al. Increased C-Reactive Protein levels in the PCOS- a marker of cardiovascular disease. J Clin Endocrinol Metabol. 2004; 89: 2160-2165. doi: http://dx.doi.org/10.1210/jc.2003-031096
54. Blumenfeld Z, Eckman A. Preservation of Fertility and Ovarian Function and Minimizing. Chemotherapy Induced Gonadotoxicity in Young Women by GnRH-A. J National Cancer Institute Monogr. 2005; 34: 40-43. doi: 10.1093/jncimonographs/lgi015
55. Kupershmidt L, Amit T, Bar-Am O, Youdim MB, Blumenfeld Z. The neuroprotective effect of Activin A and B: implication for neurodegenerative diseases. J Neurochem. 2007; 103: 962-971. doi: 10.1111/j.1471-4159.2007.04785.x
56. Rosenberg N, Soudry M, Rosenberg O, Blumenfeld I, Blumenfeld Z. The Role of Activin A in The Human Osteoblast Cell Cycle: A Preliminary Experimental in Vitro Study. Exp Clin Endocrinol Diabetes. 2010; 118: 708-712. doi: 10.1055/s-0030-1249007
57. Evron A, Blumenfeld Z. Ovarian Stem Cells-the Pros and Cons. Clin Med Insights: Reprod Health. 2013; 7: 43-47.
58. Diamond OM, Turgeman O, Blumenfeld Z. Minimizing the Doxorubicin-Induced Gonadotoxicity by Sphingosine-1-Phosphate analogue FTY720. Am J Clin Exp Obstet Gynecol. 2015; 2(1).


CLINICAL


59. Weisz GM, Blumenfeld Z, Barzilai A. Electrocardiographic changes in traumatized patients. J American College of Emergency Physicians and the Univ Ass for Emergency Med Services. 1976; 5: 329-331.
60. Blumenfeld Z, Makler A, Zimmer E, Peer E, Brandes JM. Treatment of hirsutism with Cyproterone Acetate (Androcur). Harefuah. 1980; 99: 303.
61. Blumenfeld Z, Brandes JM, Timor-Tritsch IE. Pregnancy and extrahepatic portal hypertension. Harefuah. 1980; 98: 116.
62. Dickstein G, Blumenfeld Z, Barzilai D. The diagnosis and therpeutic approach in Cushing Syndrome - A critical review. Harefuah. 1980; 98: 268.
63. Makler A, Blumenfeld Z, Zimmer E. Evaluating the treatment of the hirsutic women and acne with cyproterone acetate (Hebrew). Harefuah. 1980; 99: 303-306.
64. Kerner N, Blumenfeld Z, Friedman M, Peretz BA, Brandes JM. Brenner tumors – A clinicopathologic study of benign, borderline and malignant types. J Obstet Gynecol. 1981; 1: 251.
65. Aviram M, Blumenfeld Z, Brook J, Lavi A. High-density lipoproteins subfractions in cord blood. Singapore J Obstet Gynecol. 1982; 13: 107-114.
66. Blumenfeld Z, Toledano C, Eitan A, Barzilai A, Brandes JM. Tubo-ovarian abscess in the postmenopausal women. World J Surg. 1982; 6: 634-636.
67. Naor N, Blumenfeld Z, Merzbach D, Timor-Tritsch IE, Seltzer M. Prevalence of group B streptococci in parturient mothers and their infants. Eur J Pediatr. 1982; 138: 166-167.
68. Makler A, Jakobi P, Deutsch M, Blumenfeld Z. Homologous intra uterine insemination with centrifugated sperm resuspended within umbilical cord serum. Harefuah. 1982; 102: 137.
69. Blumenfeld Z, Brook JG, Aviram M, Brandes JM. Changes in lipoproteins and subfractions following oophorectomy and oestrogen replacement in perimenopausal women. Maturitas. 1983; 5: 77-83.
70. Brandes JM, Blumenfeld Z, Beck D, Eshkol A, Levithan E. Correlation of computed  fetoprotein clearance with actual clearance in a case of endodermal sinus tumour. J Obstet Gynecol. 1984; 4: 261.
71. Blumenfeld Z, Kerner H, Thaler I, Deutsch M, Beck D. Increased alpha fetoprotein levels in mixed mesodermal tumors of ovary. Gynecol and Obstet Invest. 1984; 17: 169-173.
72. Thaler I, Timor-Tritsch IE, Blumenfeld Z. Effect of acute hypoxemia on the human fetal heart rate - the significance of increased heart rate variability. Acta Ob Gyn Scandinavica. 1985; 64: 47-51. doi: 10.3109/00016348509154687
73. Blumenfeld Z, Kerner H, Makler A, Eshkol A, Brandes JM. Clinical endocrine and ultrastructural study of XY-gonadal dysgenesis. J Reprod Med. 1985; 30: 211.
74. Blumenfeld Z. Clinical uses of Gonadotropin-releasing hormone (GnRH) and its analogues. BAKI - Clinical Biochemistry. 1986; 5: 170.
75. Edoute Y, Blumenfeld Z, Aharoni L, Moskowitz M. Peripartum congestive cardiomyopathy and endocardial fibroelastosis associated with ritodrine treatment. J Reprod Medicine. 1987; 23(10): 793-797.
76. Andreyko JL, Blumenfeld Z, Marshall LA, Monroe SE, Hricak H, Jaffe RB. Use of an agonistic analog of Gonadotropin-releasing hormone (Nafarelin) to treat Leiomyomata: assessment by magnetic resonance imaging. Am J Obstet Gynecol. 1988; 158: 903-910.
77. Blumenfeld Z, Makler A, Frisch L, Brandes JM. Induction of spermatogenesis and fertility in hypogonadotropic azoospermic men by intravenous pulsatile GnRH. Gynecological Endocrinology. 1988; 2: 151-164.
78. Blumenfeld Z, Nahhas F. Luteal dysfunction in ovulation induction - the role of repetitive human chorionic gonadotropin supplementation during the luteal phase. Fertil Steril. 1988; 50: 403.
79. Blumenfeld Z, Frisch L, Conn PM. Gonadotropin-releasing hormone (GnRH) antibodies formation in hypogonadotropic azoospermic men treated with pulsatile GnRH - Diagnosis and possible alternative treatment. Fertil Steril. 1988; 50: 4.
80. Blumenfeld Z, Nahhas F. Pretreatment of sperm with human follicular fluid (hFF) for borderline male infertility. Fertil Steril. 1989; 51: 863-868.
81. Blumenfeld Z, Thaler I, Gilhar A. Mode of delivery in Ehler-Danlos syndrome - A reappraisal of the current status. Int J Dermatology. 1989; 28: 621-623. doi: 10.1111/j.1365-4362.1989.tb02549.x
82. Blumenfeld Z, Lunenfeld B. The potentiating effect of growth hormone on follicle stimulation with human menopausal gonadotropin in a panhypopituitary patient. Fertil Steril. 1989; 52: 328-331.
83. Bronshtein M, Rottem S, Yoffe N, Blumenfeld Z. First and early second trimester diagnosis of nuchal cystic hygroma by transvaginal sonography: Diverse prognosis of the septated from the non-septated lesion. American Journal of Obstetrics and Gynecology. 1989; 161: 78-82. doi: http://dx.doi.org/10.1016/0002-9378(89)90237-8
84. Bronshtein M, Yoffe N, Brandes JM, Blumenfeld Z. First and early second trimester diagnosis of fetal urinary tract anomalies using transvaginal sonography. Prenatal Diagnosis. 1990; 10: 653-666.
85. Yoffe N, Blumenfeld Z. Gestation and spontaneous delivery in an hydrocephalic patient with ventriculo-peritoneal shunt. Harefuah. 1990; 118: 209-210.
86. Bronshtein M, Rottem S, Yoffe N, Blumenfeld Z, Brandes JM. Early determination of fetal sex using transvaginal sonography: Technique and pitfalls. J Clin Ultrasound. 1990; 18: 302-306. doi: 10.1002/jcu.1870180414
87. Bronshtein M, Yoffe N, Blumenfeld Z, Brandes JM. The hair as a sonographic marker of ovarian teratomas - Improved identification by using transvaginal sonography and simulating model. J Clin Ultrasound. 1991; 19: 351-355.
88. Blumenfeld Z, Yoffe N, and Bronshtein M. Transvaginal sonography in infertility and reproductive endocrinology. Obstet Gynecol Survey. 1991; 46: 36-49.
89. Bronshtein M, Zimmer E, Gershoni-Baruch R, Yoffe N, Meyer, Blumenfeld Z. First and second trimester diagnosis of fetal ocular defects and associated anomalies: Report of eight cases. Obstet Gynecol. 1991; 77: 443-449.
90. Yoffe N, Bronshtein M, Brandes JM, Blumenfeld Z. Hemorrhagic ovarian cyst detection by transvaginal sonography: The great imitator. Gynecological Endocrinology. 1991; 5: 123.
91. Bronshtein M, Mashiah N, Blumenfeld I, Blumenfeld Z. Pseudoprognathism - An auxiliary sonographic sign for transvaginal sonographic diagnosis of cleft lip and palate in the early second trimester. Am J Obstet Gynecol. 1991; 165: 1314-1316. doi: :10.1016/S0002-9378(12)90751-6
92. Brenner B, Blumenfeld Z, Markiewicz W, Reisner SA. Cardiac involvement in patients with primary antiphospholipid syndrome. Journal of American College of Cardiology. 1991; 18: 931-936. doi: 10.1016/0735-1097(91)90749-Y
93. Blumenfeld Z. Growth hormone-A cogonadotropin? Its role in ovulation induction. Journal of In-Vitro Fertilization and Embryo Transfer. 1991; 8: 127-136.
94. Bronshtein M, Blumenfeld Z. First- and early second-trimester oligohydramnios- A predictor of poor fetal outcome except in iatrogenic olygohydramnios post chorionic villi biopsy. Ultrasound in Obstetrics and Gynecology. 1991; 1(4): 245-249. doi: 10.1046/j.1469-0705.1991.01040245.x
95. Bronshtein M, Lieberson A, Lieberson S, Blumenfeld Z. Clubfeet associated with hydrocephalus - New evidence of gradual dynamic development in utero. Obstet Gynecol. 1992; 79(suppl): 864-867.
96. Bronshtein M, Blumenfeld Z. Transvaginal Sonography - Detection of findings suggestive of fetal chromosomal anomalies by transvaginal sonography in the first and early second trimester. Prenatal Diagnosis. 1992; 12: 587-593.
97. Blumenfeld Z, Dirnfeld M, Abramovici H, Amit A, Bronshetein M, Brandes JM. Spontaneous fetal reduction in multiple gestations assessed by transvaginal ultrasound. Br J Ob Gyn. 1992; 99: 333-337.
98. Bronshtein M, Tzidony D, Dimant M, Hajos J, Jaeger M, Blumenfeld Z. Transvaginal sonographic measurements of the fetal adrenal glands at 12-17 weeks gestation. Am J Ob Gyn. 1993; 169: 1205-1210.
99. Bronshtein M, Yoffe N, Zimmer E, Blumenfeld Z. Early detection of fetal anomalies by transvaginal sonography. Fetal and Maternal Medicine Review. 1993; 5: 137-146.
100. Makler A, Stoler J, Blumenfeld Z, Feigin PD, Brandes JM. Investigation in real time the effect of gravitation on human spermatozoa and their tendency to swim up and to swim down. Int J Androl. 1993; 16: 251-257.
101. Ruach M, Blumenfeld Z. Late onset congenital adrenal hyperplasia - The diversity of the various diagnostic methods. Harefuah. 1993; 124: 249-253.
102. Bronshtein M, Bar-Hava I, Blumenfeld I, Bejar J, Toder V, Blumenfeld Z. The difference between septated and non-septated nuchal cystic hygroma in the early second trimester. Obstet Gynecol. 1993; 81: 683-687.
103. Baruch Y, Weiner Z, Enat R, Ronen A, Blumenfeld Z. Pregnancy after liver transplantation. Int J Gynecol Obstet. 1993; 41: 273-276.
104. Bronshtein M, Weiner Z, Abramovici H, Filmar S, Erlik Y, Blumenfeld Z. Second trimester diagnosis of fetal gallbladder anomalies by transvaginal sonography - Report of seventeen cases. Prenatal Diagnosis. 1993; 13: 851-861.
105. Blumenfeld Z, Siegler E, Bronshtein M. The early diagnosis of neural tube defect. Prenatal Diagnosis. 1993; 13: 863-871. doi: 10.1002/pd.1970130910
106. Bronshtein M, Bar-Hava I, Blumenfeld Z. Differential diagnosis of the non-visualized fetal urinary bladder by transvaginal sonography in the early second trimester. Obstet Gynecol. 1993; 82: 490-493.
107. Bronshtein M, Blumenfeld I, Cohen I, Blumenfeld Z. Fetal ultrasonographic detection of hypodontia in the Neu-Laxova syndrome. J Clin Ultrasound. 1993; 21: 648-650. doi: 10.1002/jcu.1870210915
108. Bronshtein M, Amit A, Achiron R, Noy I, Blumenfeld Z. The early prenatal sonographic diagnosis of renal agenesis: Technique and possible pitfalls. Prenatal Diagnosis. 1994; 14: 291-297. doi: 10.1002/pd.1970140409
109. Blumenfeld Z, Lorber M, Yoffe N, Scharf Y. Systemic lupus erythematosus - a predisposition for uterine cervical dysplasia. Lupus. 1994; 3: 59-61. doi: 10.1177/096120339400300112
110. Blumenfeld Z, Bentur L, Yoffe N, Alroy G, Rubin AR. Menstrual asthma - Use of a gonadotropin-releasing hormone analogue for the treatment of cyclic aggravation of bronchial asthma. Fertil Steril. 1994; 62: 197-200.
111. Blumenfeld Z. PCO - from basic science to clinical practice. European J Obstet Gynecol and Reprod Biol. 1994; 55: 29-30.
112. Bronshtein M, Blumenfeld I, Kohn J, Blumenfeld Z. Detection of cleft lip and palate by early second trimester transvaginal sonography. Obstet Gynecol. 1994; 84: 73-76.
113. Blumenfeld Z, Lang N, Kahana L, Yoffe N. Native GnRH for triggering follicular maturation in PCOS patients undergoing hMG ovulation induction. Fertil Steril. 1994; 62: 456-460.
114. Abramovici H, Dirnfeld M, Auslander R, Bornshtein J, Blumenfeld Z, Sorokin Y. Pregnancies following treatment by GnRH-a (Decapeptyl) and myomectomy in infertile women with uterine leiomyomata. Int J Fertility. 1994; 39: 150-155.
115. Makler A, Poppa E, Rosenberg B, Blumenfeld Z. Investigation in real-time of the effect of inhalational anesthetics on the motility of human spermatozoa. Isr J Obstet Gynecol. 1995; 6: 34-40.
116. Bronshtein M, Zimmer E, Blumenfeld Z. Transvaginal sonography (TVS) of the fetal urinary tract. Ultrasonoor Bulletin. 1995; 19-23.
117. Blumenfeld Z, Zimmer E, Bronshtein M. The multidirectional sonographic approach to midtrimester elevated amniotic alpha-fetoprotein or positive acetyl cholinesterase: Transvaginal, transumbilical, and transabdominal. Obstet Gynecol. 1995; 86: 565-568.
118. Bronshtein M, Zimmer EY, Blumenfeld Z. Transvaginal sonography (TVS) of the fetal urinary tract. European Journal of Ultrasound. 1996; 3: 1-7.
119. Avivi I, Blumenfeld I, Blumenfeld Z. The therapeutic potential of ozone - possible side effects. Harefuah. 1996; 130: 327-330.
120. Bronshtein M, Blumenfeld I, Blumenfeld Z. The early prenatal diagnosis of cleft lip and the decision making process for termination of pregnancy. Br J Oral Maxillofacial Surgery. 1996; 34: 486-487. doi: http://dx.doi.org/10.1597/1545-1569(1999)036<0105:TEPDCL>2.3.CO;2
121. Stahl S, Blumenfeld Z, Yarnitsky D. Carpal tunnel syndrome in pregnancy. Journal of Neurological Sciences. 1996; 136: 182-184.
122. Blumenfeld Z. The role of growth hormone (GH), GH-receptor and GH-binding protein in ovulation induction and ovarian physiology. Review Article. Isr J Obstet Gynecol. 1996; 7: 200-210.
123. Ullmann Y, Blumenfeld Z, Hakim M, Mahoul I, Sujov P, Peled I. Urgent delivery, the treatment of choice in term pregnant women with extended burn injury. Burns. 1997; 23: 157-159.
124. Blumenfeld Z, Shen-Or Z, Harel H, et al. Corticotropin-releasing factor & adrenocorticotropin tests in chronic anovulatory women: Polycystic ovary syndrome, late onset congenital adrenal hyperplasia & acanthosis-nigricans. Isr J Ob Gyn. 1997; 8: 158.
125. Assy N, Blumenfeld Z, Berkovitz D, et al. Long-term follow-up of liver transplant patients in a nonliver transplantation center. Transplantation Proceedings. 1997; 29: 2664-2666.
126. Bronshtein M, Blumenfeld I, Zimmer E, Ben-Ami M, Blumenfeld Z. Prenatal sonographic diagnosis of nasal malformations. Prenatal Diagnosis. 1998; 18: 447-454. doi: 10.1002/(SICI)1097-0223(199805)18:5<447::AID-PD280>3.0.CO;2-F
127. Blumenfeld Z, Shabadash V, Shen-Orr Z. Pathophysiology and origin of ascites in ovarian hyperstimulation syndrome. Assisted Reproduction Reviews. 1998; 8: 102-110.
128. Blumenfeld Z, Ritter M, Avivi I, Eibschitz I. Minimizing chemotherapy induced gonadotoxicity - the role of inhibin-a as a possible marker. Isr J Obstet Gynecol. 1998; 9: 108-119.
129. Blumenfeld Z, Amit A, Kerner H, Bronshtein M, Auslander R, Deutsch M. Ovarian calcifications detection by transvaginal sonography - a possible solitary marker of borderline ovarian malignancy. Israel J. Obstet. Gynecol. 1998; 9: 276-279.
130. Blumenfeld Z, Blumenfeld I, Bronshtein M. The early prenatal diagonsis of cleft lip and the decision making process. Cleft Palate - Craniofacial Journal. 1999; 105-107. doi: http://dx.doi.org/10.1597/1545-1569(1999)036<0105:TEPDCL>2.3.CO;2
131. Bronshtein M, Blumenfeld Z. Split thalami -possible auxiliary sonographic sign for the early diagnosis of agenesis of corpus callosum. Israel J Ob Gyn. 1999; 10(2): 55-58.
132. Blazer S, Zimmer EZ, Blumenfeld Z, Zelikovic I, Bronshtein M. Natural history of fetal simple renal cysts detected in early pregnancy. J Urol. 1999; 162: 812-814. doi: 10.1203/00006450-199904020-01958
133. Dirnfeld M, Bider D, Abramovici H, Calderon I, Blumenfeld. Subsequent successful pregnancy and delivery after intracytoplasmic sperm injection in a patient with XY gonadal dysgenesis. Europ J Obstet Gynecol Reprod Biol. 2000, 88: 101-102. doi: http://dx.doi.org/10.1016/S0301-2115(99)00110-4
134. Blumenfeld Z, Shapiro D, Shteinberg M, Avivi I, Nahir M. Preservation of fertility and ovarian function and minimizing gonadotoxicity in young women with systemic lupus erythematosus treated by chemotherapy. Lupus. 2000; 9(6): 401-405.
135. Lobushitzky R, Levy M, Shen-Or Z, Blumenfeld Z, Herer P, Lavie P. Long-term melatonin administration does not alter pituitary gonadal hormone secretion in normal adult men. Human Reprod. 2000; 15: 60-65.
136. Blumenfeld Z. Hirsutism – evaluation and treatment. Isr Med Assoc J. 2000; 2: 632-634.
137. Blumenfeld Z. GnRH- Antagonists instead of agonists: Change a common practice for a better-not for merely a newer one. Fertility Sterility. 76: 443-444.
138. Weiner Z, Younis JS, Blumenfeld Z, Shalev E. Assessment of uterine placental circulation in thrombophilic women. Seminars in Thrombosis & Hemostasis. 2003; 29: 213-218. doi: 10.1055/s-2003-38837
139. Blumenfeld Z. Gynecologic Concerns for young women exposed to gonadotoxic chemotherapy. Curr Opin Obstet Gynecol. 2003; 15: 359-370.
140. De Schepper J, Schiettecatte J, Veldeniers B, et al. Clinical and biological characterization of macroprolactinemia with and without prolactin-IgG complexes. Eur J Endocrinol. 2003; 149: 201-207. doi: 10.1530/eje.0.1490201
141. Quint EH, Breech L, Blumenfeld Z. Case 2005: ovarian suppression with chemotherapy in adolescents. J Pediatr Adolesc Gynecol. 2004; 17(6): 413-416. doi: http://dx.doi.org/10.1016/j.jpag.2004.09.006
142. Brenner B, Hoffman R, Carp H, Dulitsky M, Younis J, LIVE-ENOX Investigators. Efficacy and safety of two doses of enoxaparin in women with thrombophilia and recurrent pregnancy loss: the LIVE-ENOX study. J Thromb Haemost. 2005; 3(2): 227-229. doi: 10.1111/j.1538-7836.2004.01090.x
143. Bronshtein M, Arad A, Solt I, Blumenfeld Z. Pilonidal Sinus- The Tale of the Fetal Tail. European Journal of Obstetrics& Gynecology & ReproductiveBiology. 2005; 119: 255-256. doi: http://dx.doi.org/10.1016/j.ejogrb.2004.06.034
144. Dann EJ, Epelbaum R, Haim N, Ben Shahar M, Rowe JM, Blumenfeld Z. Fertility and ovarian function are preserved in women treated with an intensified regimen of cyclophosphamide, adriamycin, vincristine and prednisone (Mega-CHOP) for Non Hodgkin Lymphoma. Human Reprod. 2005; 20: 2247-2249. doi: 10.1093/humrep/dei018
145. Blumenfeld Z, Eckman A. Oncological treatments and follicular survival. Medicina Reproductiva. 2005; 11: 33-43.
146. Blumenfeld Z, Eckman A. Preservation of ovarian ferdilidad and funccion and minimization of gonadotoxicity quimiotherapia induced in young women. Medicina Reproductiva. 2005; 11: 57-76. 147. Blumenfeld Z, Eckman A. Preservation of Fertility by Gonadotropin-Releasing Hormone Agonists. GnRH-Agonisten und Ovarschutz. 2005; Suppl 1: S42-S51.
148. Blumenfeld Z. Invited Chapter Editor on: Fertility Drugs, IVF and the risk of Gynaecologic Malignancies. Chapter Editors Introduction. CME Journal of Gynecologic Oncology. 2005; 9: 235-264.
149. Lowenstein L, Solt I, Blumenfeld Z. Invited Chapter Editor on ART and Gynecologic Cancer: Drawbacks of Assisted Reproductive Technology in the Offsprings: retinoblastoma, Beckwith-Wiedemann, and Angelman syndromes. CME Journal of Gynecologic Oncology. 2005; 9: 253-255.
150. Blumenfeld Z. Invited Chapter Editor on ART and Gynecologic Cancer. Drawbacks of Assisted Reproductive Technology-Chapter Editors Conclusions. CME Journal of Gynaecologic. Oncology. 2005; 9: 264.
151. Sarig G, Blumenfeld Z, Leiba R, Lanir N, Brenner B. Modulation of Systemic Hemostatic Parameters by Low Molecular Weight Heparin during Gestation of women with Pregnancy Loss. Thromb Haemost. 2005; 94(5): 980-985. doi: http://dx.doi.org/10.1160/TH05-03-0212
152. Blumenfeld Z, Lowenstein L, Brook O, Gonen R, Ophir E, Samueloff A. Does Maternal Height Affect Triplets Birth Weight?. Med Sci Monit. 2006; 12: CR40-CR43.
153. Elis A, Tevet A, Yerushalmi R, et al. Fertility status among women treated for aggressive non-Hodgkins lymphoma. Leukemia & Lymphoma. 2006; 47: 623-627. doi: 10.1080/10428190500353877
154. Sarig G, Aberbach I, Schliamser L, Blumenfeld Z, Brenner B. Evaluation of ProC Global assay in women with a history of venous thromboembolism on hormonal therapy. Thromb Haemost. 2006; 96: 578-583. doi: http://dx.doi.org/10.1160/TH06-05-0285
155. Blumenfeld Z, Boulman N, Leiba R, et al. High C-reactive protein Levels are associated with Oral Hormonal Menopausal Therapy but Not with Intrauterine Levonorgestrel and Transdermal Estradiol. The Scandinavian Journal of Clinical & Laboratory Investigation. 2007; 67: 257-263. doi: 10.1080/00365510601113241
156. Blumenfeld Z. Gender difference: fertility preservation in young women but not in men exposed to gonadotoxic chemotherapy. Minerva Endocrinol. 2007; 32: 23-34.
157. Blumenfeld Z, Avivi I, Eckman A, Epelbaum R, Rowe JM, Dann EJ. Gonadotropin Releasing Hormone Agonist Decreases Chemotherapy Induced Gonadotoxicity and Premature Ovarian Failure in Young Female Patients With Hodgkin Lymphoma. Fertil Steril. 2008; 89: 166-173. doi: http://dx.doi.org/10.1016/j.fertnstert.2007.02.010
158. Sills ES, Qublan HS, Blumenfeld Z, et al. A collaborative transnational pilot survey of in vitro fertilization programs in the Middle East. J Exp Clin Assist Reprod. 2007; 4(1): 3.
159. A,B,C,D- Blumenfeld Z. Debate: How to preserve fertility in young women exposed to chemotherapy? The role of GnRH-agonist in addition to cryopreservation of embryos, oocytes, or ovaries. The Oncologist. 2007; 12: 1044-1054. doi: 10.1634/theoncologist.12-9-1044
160. Blumenfeld Z Fertility Preservation sands exposed to chemotherapy. Cancer Medicine. 2007; 5: 14-17.
161. Blumenfeld Z. Fertility Preservation sands exposed to chemotherapy. Ob. Gyn. Medicine. 2008.
162. Blumenfeld Z, Von Wolff M. GnRH-analogues and oral contraceptives for fertility preservation in women during chemotherapy. Human reproduction Update. 2008; 14: 543-152. doi: 10.1093/humupd/dmn022.
163. Blumenfeld Z. Editorial-Recent Developments in Clinical Medicine: Reproductive Health. Clinical Medicine: Reproductive Health. 2008: 2: 1-3.
164. Blumenfeld Z. GnRH-agonists in fertility preservation. Current Opinion in Endocrinology, Diabetes, and Obesity. 2008; 15(6): 523-528. doi: 10.1097/MED.0b013e32831a46e9
165. Blumenfeld Z, Abdallah W, Sela-Guttmann O, Brook OR. Triplet Gestation- Prevention, Risks, & Management Dilemmas. The Open Women Health Journal. 2008; 2: 11-21.
166. Blumenfeld Z, Abdallah W, Kaplan D, Nevo O. Endometrial thickness- a practical prospective marker for the risk of surgical intervention after RU486 induced abortion. Clinical Medicine: Reproductive Health. 2008: 2; 25-30.
167. Blumenfeld Z. Premature ovarian failure: etiology and possible prevention. Expert Review of Endocrinology & Metabolism. 2009; 4: 173-181. doi: 10.1586/17446651.4.2.173
168. Blumenfeld Z. Premature ovarian failure - a possible etiology and prevention. מדיסין. 2009.
169. Bronshtein M, Khatib N, Blumenfeld Z. Prenatal Diagnosis and Outcome of Isolated Interrupted Inferior Vena Cava. Amer J Obstet Gynecology, Am J Obstet Gynecol. 2010; 202: 398.e1-e4. doi: 10.1016/j.ajog.2009.11.014
170. Blumenfeld Z, Zuckerman T. Repeated spontaneous pregnancies and successful deliveries after repeated autologous stem cell transplantation and GnRH-agonist. Oncologist. 2010; 15: 59-60.
171. Younis J, Shukha M, Ben-Ami M, et al. Prospective Evaluation of the Protein C Global Assay during Pregnancy Following Assisted Reproduction. Obstet Gynecol. 2010; 115: 969-974. doi: 10.1097/AOG.0b013e3181db67f3
172. Blumenfeld Z. Fertility Treatment in Women with Premature Ovarian Failure. Expert Rev. Obstet. Gynecol. 2011; 6; 321-330.
173. Blumenfeld Z, Mischari O, Schultz N, Boulman N, Balbir-Gurman A. Gonadotropin Releasing Hormone Agonists May Minimize Cyclophosphamide associated Gonadotoxicity in SLE and Autoimmune Diseases. Semin Arthritis Rheum. 2011; 41: 346-352. doi: 10.1016/j.semarthrit.2011.05.008.
174. Bronshtein M, Zimmer Z, Blazer S, Blumenfeld Z. Right Ductus Arteriosus- Facts and Theory. Eur J Obstet Gynecol. 2011; 159: 282-288. doi: 10.1016/j.ejogrb.2011.07.047
175. Dann EJ, Blumenfeld Z, Bar-Shalom R, et al. A 10-year experience with treatment of high and standard risk Hodgkin disease: Six cycles of tailored BEACOPP, with interim scintigraphy, are effective and female fertility is preserved. Am J Hematol. 2012; (87)1: 32-36. doi: 10.1002/ajh.22187
176. Blumenfeld Z. Chemotherapy and Fertility. Best Pract Res Clin Obstet Gynaecol. 2012; 26: 379-390. doi: 10.1016/j.bpobgyn.2011.11.008
177. Zimmer Z, Blazer S, Blumenfeld Z, Bronshtein M. Fetal Transient Clitoromegaly and Transient Hypertrophy of Labia Minora in Early and Mid Pregnancy. J Ultrasound Med. 2012; 31: 409-415.
178. Blumenfeld Z. Gonadotropin-releasing hormone analog cotreatment for preservation of ovarian function. Oncologist. 2012; 17: 162-163. doi: 10.1016/j.fertnstert.2010.11.017
179. Bronshtein M, Zimmer EZ, Blazer S, Blumenfeld Z. Transient abnormal fetal cardiac flow patterns at 13 to 17 gestational weeks. Prenat Diagn. 2012; 32: 444-449. doi: 10.1002/pd.3836
180. Blumenfeld Z. Epigenetics and vitrification of embryos: one step forward and many raised equivocal questions. Fertil Steril. 2012; 98: 41-42. doi: 10.1016/j.fertnstert.2012.04.031
181. Blumenfeld Z. GnRH-a for Preservation of Ovarian Function during (Neo) Adjuvant Chemotherapy for Breast Cancer. J Clin Oncol. 2012; 30: 3310.
182. Blumenfeld Z, Patel B, Leiba R, Zuckerman T. Gonadotropin Releasing Hormone agonist may minimize premature ovarian failure in young women undergoing autologous stem cell transplantation. Fertil Steril. 2012; 98: 1266-1270. doi: 10.1016/j.fertnstert.2012.07.1144
183. Khatib N, Blumenfeld Z, Bronshtein M. Early Prenatal Diagnosis of Tricuspid Stenosis. Am J Obstet Gynecol. 2012; 207(5): e6-e8. doi: 10.1016/j.ajog.2012.08.030.
184. Blumenfeld Z. Preservation of ovarian function and fertility despite gonadotoxic chemotherapy. Expert Review Endocrinol Metabol. 2012; 7: 567-576. doi: 10.1586/eem.12.40)
185. Tripto-Shkolnik L, Blumenfeld Z, Bronshtein M, Salmon A, Jaffe A. Pregnancy in a Patient with Adrenal Carcinoma Treated with Mitotane: A Case Report and Review of Literature. J Clin Endocrinol Metab. 2013; 98: 443-447. doi: 10.1210/jc.2012-2839
186. Blumenfeld Z, Katz G, Evron A. An ounce of prevention is worth a pound of cure- The case for and against GnRH-agonist for fertility preservation. Annals of Oncology. 2014; 25: 1719-1728.
187. Bronshtein M, Solt I, Blumenfeld Z. The advantages of early midtrimester targeted fetal systematic organ screening for the detection of fetal anomalies- will a global change start in Israel? Harefuah. 2014; 153: 320-324, 368.
188. Blumenfeld Z, Khatib N, Zimmer EZ, Bronshtein M. Fetal demise in the early second trimester: sonographic findings. J Clin Ultrasound. 2015; 43: 109-122. doi: 10.1002/jcu.22204